Keywords: شکستن شرط; Arginase deficiency; Hyperargininemia; Ammonia; Urea cycle disorder; Treatment; Cellular transplant; FAH; fumarylacetoacetate hydrolase; FRG; Fahâ/â/Rag2â/â/Il2rγâ/â mouse; CKO; conditional knockout; NTBC; 2-(2-nitro-4-trifluoromethylbenzoyl)
مقالات ISI شکستن شرط (ترجمه نشده)
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Keywords: شکستن شرط; Steroidogenesis; Mitochondria; Translocator Protein (TSPO); Steroidogenic Acute Regulatory Protein (StAR); Conditional knockout; Global knockout;
Keywords: شکستن شرط; ASD; autism spectrum disorders; BTBR; BTBR T+Itpr3tf/J mouse strain; cKO; conditional knockout; CNS; central nervous system; CNTNAP2; contactin-associated protein-like 2; DREADD; designer receptors exclusively activated by designer drugs; DSM-5; Diagnosti
Keywords: شکستن شرط; TFPI-2; Conditional knockout; Atherosclerosis; Matrix metalloproteinase; PPAR-α; PPAR-γ;
Keywords: شکستن شرط; aCSF; artificial cerebrospinal fluid; cKO; conditional knockout; EGTA; ethylene glycol tetraacetic acid; fEPSPs; field excitatory postsynaptic potentials; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; LTP; long-term potentiation; MGE; medial
Keywords: شکستن شرط; Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Keywords: شکستن شرط; LECs; lens epithelial cells; LFCs; lens fiber cells; ECM; extracellular matrix; IGF; insulin-like growth factor; OCFs; outer cortical fibers; ICFs; inner cortical fibers; F-actin; filamentous actin; cKO; conditional knockout; ILK; integrin linked kinase;
Keywords: شکستن شرط; AAV; adeno-associated virus; ANOVA; analysis of variance; ARG; arginase; HPF; high-power field; OAT; ornithine amino transferase; PCR; polymerase chain reaction; RT-PCR; reverse transcription-polymerase chain reaction; TBS; Tris-buffered saline; Arginase
Hepatic conditional knockout of ATF6 exacerbates liver metabolic damage by repressing autophage through MTOR pathway
Keywords: شکستن شرط; Metabolism; ATF6; Conditional knockout; Autophage; ATF6; activating transcription factor 6; UPR; unfolded protein response; GTT; glucose tolerance test; ITT; insulin tolerance test; RES; resveratrol; DEX; dexamethasone; FSK; forskolin; TG; triglyceride; T
The p38α MAPK Deletion in Oligodendroglia does not Attenuate Myelination Defects in a Mouse Model of Periventricular Leukomalacia
Keywords: شکستن شرط; CKO; conditional knockout; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; GFP; green fluorescent protein; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; MBP; myelin basic protein; NG2; neuron-glial antigen 2
Conditional loss of Kcnj13 in the retinal pigment epithelium causes photoreceptor degeneration
Keywords: شکستن شرط; Leber congenital amaurosis; KCNJ13; Kir7.1; Photoreceptors; Retinal degeneration; Conditional knockout; RPE; Retinal function;
In vivo identification of Bmp2-correlation networks during fracture healing by means of a limb-specific conditional inactivation of Bmp2
Keywords: شکستن شرط; Bmp2; Fracture healing; Co-expression; Differential gene expression; Conditional knockout; Networks;
Myelin volume fraction imaging with MRI
Keywords: شکستن شرط; MRI; magnetic resonance imaging; MWF; myelin water fraction; BPF; bound pool fraction; fM,T2; myelin volume fraction from MWF; fM,MT; myelin volume fraction from BPF; MVF; myelin volume fraction; AVF; axon volume fraction; fM,HIST; myelin volume fraction
Functional significance of O-GlcNAc modification in regulating neuronal properties
Keywords: شکستن شرط; PTM; post-translational modification; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; GalNAc; N-acetylgalactosamine; Gal; galactose; PSD; postsynaptic density; NF
The histone demethylase Kdm6b regulates a mature gene expression program in differentiating cerebellar granule neurons
Keywords: شکستن شرط; CGNs; cerebellar granule neurons; GNPs; granule neuron precursors; EGL; external granule layer; IGL; internal granule layer; H3K4me1 or H3K4me3; histone H3 lysine 4 monomethylation or trimethylation; H3K27me3; histone H3 lysine 27 trimethylation; JmjC; ju
TGF-β Signaling Regulates Development of Midbrain Dopaminergic and Hindbrain Serotonergic Neuron Subgroups
Keywords: شکستن شرط; 5-HT; 5-hydroxytryptamine; Aldh1a1; aldehyde dehydrogenase 1 family member A1; Cck; cholecystokinin; cKO; conditional knockout; DIV; day in vitro; DR; dorsal raphe; MR; median raphe; PMR; paramedian raphe; RM; raphe magnus; En1; engrailed 1; ES; embryonic
A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility
Keywords: شکستن شرط; DEPDC5; Focal cortical dysplasia; mTOR; Familial focal epilepsy; Seizures; Conditional knockout; Megalencephaly;
Oocyte-specific deletion of Gsα induces oxidative stress and deteriorates oocyte quality in mice
Keywords: شکستن شرط; Gsα; Conditional knockout; Infertility; Oxidative stress; Mitochondria; Mouse oocyte;
Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing
Keywords: شکستن شرط; cKO; conditional knockout; McSC; melanocyte stem cell; TAM; tamoxifen; Tyr; tyrosinase;
La involvement in tRNA and other RNA processing events including differences among yeast and other eukaryotes
Keywords: شکستن شرط; cKO; conditional knockout; DFC; dense fibrillar component; LaM; La motif; LARP; La-related protein; m7G-cap; 7-methyl-guanosine-cap; RRM; RNA recognition motif; RNAP; RNA polymerase; snRNA; small nuclear RNA; tRFs; tRNA fragments; tRNAome; tRNA gene conte
Conditional loss of Spata7 in photoreceptors causes progressive retinal degeneration in mice
Keywords: شکستن شرط; Retinitis Pigmentosa; Leber Congenital Amaurosis; SPATA7; Photoreceptors; Retinal degeneration; Conditional knockout; RPE; Retinal function;
MiR-31 Mediates Inflammatory Signaling to Promote Re-Epithelialization during Skin Wound Healing
Keywords: شکستن شرط; 3â²-UTR; 3â²-untranslated region; Ccnd1; Cyclin D1; cKO; conditional knockout; MAPK; mitogen-activated protein kinase; PWD; post wounding; siRNA; small interfering RNA; STAT3; signal transducer and activator of transcription 3; TNF-α; tumor necrosis fa
Loss of transforming growth factor-β1 in epithelium cells affects enamel formation in mice
Keywords: شکستن شرط; Transforming growth factor-beta1; Conditional knockout; Enamel mineralization; Ameloblasts; Enamel matrix protein;
Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice
Keywords: شکستن شرط; Pten; Ovary theca cells; Conditional knockout; PI3K; LHCGR; PCOS;
Slug Modulates UV Radiation-Induced Cutaneous Inflammation by Regulating Epidermal Production of Proinflammatory Cytokines
Keywords: شکستن شرط; CKO; conditional knockout; KO; knockout; OSM; oncostatin; TG; transgenic; WT; wild type;
Wls expression in the rhombic lip orchestrates the embryonic development of the mouse cerebellum
Keywords: شکستن شرط; BGC; Bergmann glia cell; cKO; conditional knockout; CN; cerebellar nuclear; CP; choroid plexus; E; embryonic; EGL; external germinal layer; eRL; exterior face of the rhombic lip; GCP; granule cell progenitor; GC; granule cell; IHC; immunohistochemical; iR
Osteogenesis imperfecta: new genes reveal novel mechanisms in bone dysplasia
Keywords: شکستن شرط; ADAMTS; A disintegrin and metalloprotease with thrombospondin motifs; AR-OI; autosomal recessive osteogenesis imperfecta; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; BiP; binding immunoglobulin protein; BMDD; bone mineraliz
MicroRNA control of tooth formation and eruption
Keywords: شکستن شرط; RISC; RNA-induced silencing complex; miRNAs; microRNAs; UTR; untranslated region; cKO; conditional knockout; laCL; labial cervical loop; liCL; lingual cervical loop; DFC(s); dental follicle cell(s); MicroRNA; Tooth development; Amelogenesis; Odontoblast;
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice
Keywords: شکستن شرط; Growth retardation; Hyperkeratosis; Erythrocyte; Conditional knockout; NDRG; N-myc downstream regulated gene; ES; embryonic stem; PP; Peyer's patches; wt; wild-type; wp; white pulp; rp; red pulp;
Dot1l deficiency leads to increased intercalated cells and upregulation of V-ATPase B1 in mice
Keywords: شکستن شرط; V-ATPase; Histone methyltransferase Dot1l; Conditional knockout; Principal cells; Intercalated cells
Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord
Keywords: شکستن شرط; KO; bcl-x conditional knockout; Bcl-2 proteins; Development; Neurogenesis; Apoptosis; Conditional knockout; Mouse;
Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains
Keywords: شکستن شرط; AC; anterior commissure; AD; axial diffusivity; AK; axial kurtosis; CKO; conditional knockout; da; axon diameter; Da; intra-axonal diffusivity; De,||; extra-axonal axial diffusivity; De,â¥; extra-axonal radial diffusivity; DKI; diffusion kurtosis imaging
Neuronal vs glial glutamate uptake: Resolving the conundrum
Keywords: شکستن شرط; Glutamate uptake; EAAT2; Glutamate transporter; Conditional knockout; Synaptosomes; Axon-terminalsCre, Cyclization recombinase (Le and Sauer, 2000); EAAC1, glutamate transporter (EAAT3, slc1a1, Kanai and Hediger, 1992, Bjørås et al., 1996); EAAT, excitato
Short CommunicationDelta opioid receptors expressed in forebrain GABAergic neurons are responsible for SNC80-induced seizures
Keywords: شکستن شرط; DOR; delta opioid receptor; EEG; electroencephalogram; Delta opioid receptor; Conditional knockout; Epileptic seizure; Delta agonist; Biased agonism; In vivo;
β-Catenin is required for maintaining hippocampal morphology during the perinatal period
Keywords: شکستن شرط; BCIP; 5-bromo-4-chloro-3-indolyl-phosphate; BSA; Bovine Serum Albumin; CA; Cornu Ammonis; CKO; conditional knockout; DG; dentate gyrus; EDTA; ethylenediaminetetraacetic acid; GFAP; glial fibrillary acidic protein; ISH; In situ hybridization; NBT; nitro bl
Fgfr2 is required for the expansion of the early adrenocortical primordium
Keywords: شکستن شرط; Adrenocortical primordium; Proliferation; Coelomic epithelium; Conditional knockout; Tbx18; Fgfr2
Connexin26 (GJB2) deficiency reduces active cochlear amplification leading to late-onset hearing loss
Keywords: شکستن شرط; 4-HTMX; 4-hydroxytamoxifen; ABR; auditory brainstem response; cKO; conditional knockout; DPOAE; distortion product otoacoustic emission; EP; endocochlear potential; KO; knockout; NLC; nonlinear capacitance; OHC; outer hair cells; gap junction; connexin; C
Tie1 is required for lymphatic valve and collecting vessel development
Keywords: شکستن شرط; Tie1; Lymphatic valve; Lymphovenous valve; Lymphatic vessel remodeling; Conditional knockout; Prox1;
Thalamic adenylyl cyclase 1 is required for barrel formation in the somatosensory cortex
Keywords: شکستن شرط; 5-HTT; serotonin transporter; AC1; adenylyl cyclase 1; CO; cytochrome oxidase; Cx-AC1KO; cortex-specific AC1 knockout; NMDAR; N-methyl-d-aspartate receptor; PB; phosphate buffer; PFA; paraformaldehyde; PKA; protein kinase A; PMBSF; posterior medial barrel
Original Full Length ArticleAnti-DKK1 antibody promotes bone fracture healing through activation of β-catenin signaling
Keywords: شکستن شرط; Dkk1-Ab; β-Catenin; Conditional knockout; Fracture healing; Mesenchymal progenitor cells;
MicroRNAs in skin tissue engineering
Keywords: شکستن شرط; APC; antigen producing cell; Ago; argonaute protein; αSMA; alpha smooth muscle actin; BSE; bioengineered skin equivalent; CEA; cultured epithelial autograft; cKO; conditional knockout; CREB1; p-cAMP response element-binding protein 1; DMD; Duchenne muscu
APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart
Keywords: شکستن شرط; APC; adenomatosis polyposis coli; cKO; conditional knockout; CM; cardiomyocyte; E; embryonic day; WT; wild type; Adenomatosis polyposis coli (APC); β-catenin; Heart; Development; Wnt; Proliferation;
Conditional removal of selectable markers in Trypanosoma cruzi using a site-specific recombination tool: Proof of concept
Keywords: شکستن شرط; DiCRE; loxP; Selectable markers removal; Conditional knockout; Chagas disease
Protection by vascular prostaglandin E2 signaling in hypoxic-ischemic encephalopathy
Keywords: شکستن شرط; PGE2 EP4 receptor; Hypoxic-ischemic encephalopathy; Endothelium; Cerebral protection; Conditional knockout;
Research ArticleDifferential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice
Keywords: شکستن شرط; hBidâ/â; hepatocyte-specific Bid knockout; cKO; conditional knockout; Bidfl/fl; albumin-cre negative Bid flox/flox control; WT; wild-type; TUNEL; terminal desoxynucleotidyl transferase-mediated dUTP-biotin nick and labeling; MIP; macrophage inflammato
How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?
Keywords: شکستن شرط; Dab1; disabled homolog 1; ApoER2; apolipoprotein E receptor 2; VLDLR; very-low-density lipoprotein receptor; VZ; ventricular zone; SVZ; subventricular zone; MAZ; multipolar cell accumulation zone; CP; cortical plate; IZ; intermediate zone; MZ; marginal zo
Age-dependent neuron loss is associated with impaired adult neurogenesis in forebrain neuron-specific Dicer conditional knockout mice
Keywords: شکستن شرط; miRNA; microRNA; cKO; conditional knockout; AD; Alzheimer's disease; DG; dentate gyrus; SGZ; subgranular zone; SVZ; subventricular zone; GCL; granular cell layer; MAP2; microtubule-associated protein; SVP38; synaptophysin; GFAP; glial fibrillary acidic pr
In Vivo Mn-Enhanced MRI for Early Tumor Detection and Growth Rate Analysis in a Mouse Medulloblastoma Model
Keywords: شکستن شرط; 2D; two-dimensional; 3D; three-dimensional; Cb; cerebellum; CKO; conditional knockout; GCP; granule cell precursor; IHC; immunohistochemistry; MB; medulloblastoma; MEMRI; Mn-enhanced MRI; Mn; manganese; MRI; magnetic resonance imaging; Ptch1; Patched-1; S
Generation and characterization of a conditional deletion allele for Lmna in mice
Keywords: شکستن شرط; Lamins; Laminopathies; Lmna; Conditional knockout; Gene targeting; Cre-loxP;
Role for Lhx2 in corticogenesis through regulation of progenitor differentiation
Keywords: شکستن شرط; cKO; conditional knockout; dTel; dorsal telencephalon; SVZ; subventricular zone; VZ; ventricular zone; WT; wild type; Cortical neurogenesis; Lhx2; Hes1; Notch; floxed Lhx2;