Keywords: 8-OHdG; 8-hydroxy-2-deoxyguanosine; Îym; mitochondrial membrane potential; AMPK; AMP-activated protein kinase; apoB; apolipoprotein B; AST; aspartate transaminase; ALT; alanine transaminase; ATP; adenosine triphosphate; CPT-1; carnitine palmitoyl-transfe
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Keywords: Methionine; Apoptosis; Lipid deposition; Lipid metabolism; Signaling pathway; AKT; RAC-alpha serine/threonine-protein kinase; AMPK; AMP-activated kinase; APO; Apolipoprotein; cAMP; Cyclic AMP; CPT-1; Carnitine palmitoyl transferase-1; CREBCyclic; AMP-resp
Keywords: AKI; acute kidney injury; ATP5a1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha 1; Bax; BCL2 associated X; BUN; blood urea nitrogen; CREA; serum creatinine; CC; creatinine clearance; CCK-8; cell counting kit-8; CD36; cluster of differenti
Keywords: Garlic; Alcoholic liver disease; Reactive oxygen species; Nrf-2; Kupffer cells; Adiponectin; AC; alcoholic cirrhosis; ACC; acetyl-CoA carboxylase; AF; alcoholic fibrosis; AFL; alcoholic fatty liver; AGE; aged garlic extract; AH; alcoholic hepatitis; ALD;
Keywords: ACC; acyl-CoA carboxylase; ACOX; acetyl-CoA oxidase; AFL; alcoholic fatty liver; ALD; alcoholic liver disease; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AMPK; AMP-activated protein kinase; CPT-1; carnitine palmitoyltransferase 1; CYP
Keywords: HMG-CoA; 3-hydroxy-3-methyl-glutaryl-coenzyme A; 3-V Bio; 3-V Biosciences, Inc.; AMPK; AMP activated protein kinase; AR; androgen receptor; ChREBP; carbohydrate-activated transcription factor response element binding protein; CPT-1; carnitine palmitoyltra
Keywords: IL-6; interleukin-6; ND; normal diet; HFD; high fat diet; FAs; fatty acids; CD36; cluster of differentiation 36; MCP-1; monocyte chemoattractant protein 1; PPARα; peroxisome proliferator-activated receptor α; CPT-1; carnitine palmitoyltransferase 1; End
Keywords: ACLI; acute cardiogenic liver injury; ADP; adenosine diphosphate; ATP; adenosine triphosphate; BNP; B-type natriuretic protein; CE; capillary electrophoresis; CH; cardiac hepathopathy; CK; creatine kinase; CPT-1; carnitine palmitoyltransferase-1; CRT; car
Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: Resveratrol; Pigs; Lipid metabolism; Obesity; Visceral adipose tissue; TC; total cholesterol; HDL-C; high density lipoprotein cholesterol; LDL-C; low density lipoprotein cholesterol; GOT; aspartate aminotransferase; GPT; alanine aminotransferase; PPARγ;
Keywords: Adenosine monophosphate-activated protein kinase; Clock genes; Peroxisome proliferator-activated receptor α; Lipogenic genes; Fatty liver; High-fat diet; ACC-1α; acetyl-CoA carboxylase 1α; AMPK; adenosine monophosphate-activated protein kinase; A
Keywords: AgRP; agouti-related peptide; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; CaMKII; calcium/calmodulin dependent protein kinase II; Cox6a2; cytochrome c oxidase subunit VI peptide 2a; CPT-1; carnitine palmitoyltransferase 1; ETC; ele
Keywords: Diabetes; Cancer; Insulin; Anti-diabetics; Cannabinoid; Obesity; 2-AG; 2-arachidonoyl glycerol; ACC; acetyl-CoA carboxylase; AMPK; adenosine monophosphate-activated protein kinase; CB1R; cannabinoid 1 receptor; CB2R; cannabinoid 2 receptor; CPT-1; carniti
Keywords: BMI; body mass index; OVX; ovariectomy; CPT-1; carnitine palmitoyltransferase-1; ACC; acetyl CoA carboxylase; SREBP-1c; sterol regulatory element-binding protein-1c; FAS; fatty acid synthase; LSP; less pungent red pepper; MSP; moderately pungent red peppe
Keywords: DBSs; dried blood spots; CPT-1; carnitine palmitoyltransferase 1; VLCAD; very-long-chain acyl-CoA dehydrogenase; LCHAD; long-chain 3-hydroxyacyl-CoA dehydrogenase; MCAD; medium-chain acyl-CoA dehydrogenase; PA; propionic acidemia; MMA; methylmalonic acide
Keywords: ACC; Acetyl CoA carboxylase; ATP; adenosine triphosphate; ATGL; adipose triglyceride lipase; AMPK; AMP-activated protein kinase; Ang I; angiotensin I; Ang II; angiotensin II; ACE; angiotensin converting enzyme; ACE2; angiotensin converting enzyme 2; AT1R;
Keywords: ROS; reactive oxygen species; NR; nuclear receptor; FA; fatty acid; TAG; triacylglycerol; MCD; malonyl-CoA decarboxylase; ACC; acetyl-CoA carboxylase; FAS; fatty acid synthase; SCD1; stearoyl-CoA desaturase-1; G-3-P; glycerol 3-phosphate; CPT-1; carnitine
Global microRNA and isomiR expression associated with liver metabolism is induced by organophosphorus flame retardant exposure in male Chinese rare minnow (Gobiocypris rarus)
Keywords: OPFRs; Organophosphorus flame retardants; TBOEP; Tris(2âbutoxyethyl) phosphate; TDCIPP; Tris(1,3âdichloroâ2âpropyl) phosphate; TPHP; Triphenyl phosphate; BFRs; Brominated flame retardants; HTS; High-throughput sequencing; miRNA; MicroRNA; CTD; Com
Chlamydia pneumoniae exploits adipocyte lipid chaperone FABP4 to facilitate fat mobilization and intracellular growth in murine adipocytes
Keywords: Chlamydia pneumoniae; Adipocytes; Infection; Lipolysis; Fatty acid-binding protein 4; ATGL; adipose triglyceride lipase; HSL; hormone sensitive lipase; MGL; monoglyceride lipase; FABP4; fatty acid binding protein 4; FFAs; free fatty acids; LD; lipid dropl
Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway
Keywords: ASC; apoptosis-associated speck-like protein; CPT-1; carnitine palmitoyl transferase-1; GST; glutathione S-transferase; HO-1; hemeoxygenase-1; H2O2; hydrogen peroxide; IL; interleukin; Keap1; Kelch-like ECH-associated protein 1; MDA; malondialdehyde; miR-
Platycodon grandiflorum-derived saponin enhances exercise function, skeletal muscle protein synthesis, and mitochondrial function
Keywords: Platycodon grandiflorum; Saponin; Exercise function; Skeletal muscle synthesis and breakdown; Oxidative phosphorylation; CPT-1; carnitine palmitoyltranserase; ERK; extracellular-signal-regulated kinases; mTOR; mammalian target of rapamycin; MHC; myosin he
Extruded sorghum (Sorghum bicolor L.) reduces metabolic risk of hepatic steatosis in obese rats consuming a high fat diet
Keywords: Sorghum; Adipogenese; Anthocyanin; Bioactive compounds; β-Oxidation; Tannins; 3-DXA; 3-deoxyanthocyanidins; ACC; acetyl coenzyme-A carboxylase; ADIPO-R2; adiponectin receptor; BMI; body mass index; CPT-1; carnitine palmitoyl ttransferase; FAS; fatty acid
Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways
Keywords: Arctigenin; Lipotoxicity; Steatosis; Inflammation; Nonalcoholic fatty liver disease; ACC1; acetylcoenzyme A carboxylase 1; ACO; acyl-CoA oxidase; ATG; arctigenin; CPT-1; carnitine palmitoyltransferase 1; FAS; fatty acid synthase; MDA; malondialdehyde; NAF
The polyherbal drug GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica inhibits hepatic steatosis and fibroinflammtion in high-fat diet-induced obese mice
Keywords: α-SMA; α-smooth muscle actin; ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; AST; aspartate transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; ECM; extracellular m
Human-based systems: Mechanistic NASH modelling just around the corner?
Keywords: Elafibranor (PubChem CID: 9864881); Obeticholic acid (PubChem CID: 447715); Pioglitazone (PubChem CID: 4829); Rosiglitazone (PubChem CID: 77999); Fenofibrate (PubChem CID: 3339); Serine (PubChem CID: 5951); ACC1; acetyl-coenzyme A carboxylase 1; AdipoR; a
Non-alcoholic fatty liver disease and its treatment with n-3 polyunsaturated fatty acids
Keywords: NAFLD; Omega-3 fatty acids; Fish oil; Algal oil; Insulin resistance; Metabolic syndrome; ALA; alpha-linolenic acid; ALT; alanine aminotransferase; Apo; apolipoprotein; AST; aspartate aminotransferase; BMI; body mass index; ChREBP; carbohydrate response el
Kaempferol slows intervertebral disc degeneration by modifying LPS-induced osteogenesis/adipogenesis imbalance and inflammation response in BMSCs
Keywords: IVD; intervertebral disc; BMSCs; mesenchymal stem cells; LPS; lipopolysaccharide; PCNA; proliferation cell nuclear antigen; MMP; matrix metalloprotease; CPT-1; carnitine palmitoyl transferase-1; PPAR-γ; peroxisome proliferators-activated receptor-γ; IL;
LIGHT is increased in patients with coronary disease and regulates inflammatory response and lipid metabolism in oxLDL-induced THP-1 macrophages
Keywords: LIGHT; Inflammation; Hyperlipidemia; Atherosclerosis; NF-κB; TNSF14/LIGHT; tumor necrosis factor superfamily member 14; oxLDL; oxidized low-density lipoproteins; NF-κB; nuclear factor-kappa B; LDLs; low-density lipoproteins; TNFSF; tumor necrosis factor
Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene expression
Keywords: Alcoholic liver injury; Cytochrome P450 2E1; Oxidative stress; Peroxisome proliferator-activated receptor alpha; Lipogenic genes; Apigenin; CPT-1; carnitine palmitoyltransferase-1; CYP2E1; cytochrome P450 2E1; DGAT; diacylglycerol acyltransferase; FAS; fa
Saponins from the roots of Platycodon grandiflorum ameliorate high fat diet-induced non-alcoholic steatohepatitis
Keywords: ACOX; acyl-CoA oxidase; ARE; antioxidant response element; CKS; Platycodon grandiflorum root-derived saponins; CPT-1; carnitine palmitoyltransferase-1; HFD; High fat diet; HSCs; hepatic stellate cells; NAFLD; non-alcoholic fatty liver disease; NASH; non-a
Sesame oil lignans inhibit hepatic endoplasmic reticulum stress and apoptosis in high-fat diet-fed mice
Keywords: CHOP; C/EBP homologous protein; CPT-1; carnitine palmitoyl transferase 1; ER; endoplasmic reticulum; FAS; fatty acid synthase; GC; gas chromatography; GRP78; 78-kDa glucose-regulated protein; HFD; high-fat diet; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reduc
d-Psicose, a sugar substitute, suppresses body fat deposition by altering networks of inflammatory response and lipid metabolism in C57BL/6J-ob/ob mice
Keywords: Abcd2; ATP-binding cassette, sub-family D, member 2; aP2; adipocyte protein 2; C/EBP-α; CCAAT/enhancer-binding protein-alpha; CPT-1; carnitine palmitoyltransferase-1; FAS; fatty acid synthase; FC; fold change; Fgf21; fibroblast growth factor 21; Fos; FBJ
Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice
Keywords: ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; DF; Gangjihwan; FAS; fatty acid synthase; HE; hematoxylin-eosin; HFD; high fat di
Saponins from stems and leaves of Panax ginseng prevent obesity via regulating thermogenesis, lipogenesis and lipolysis in high-fat diet-induced obese C57BL/6 mice
Keywords: Anti-obesity; Saponins; Panax ginseng; C57BL/6 mice; Haematoxylin and eosin; RT-PCR; aP2; adipocyte fatty acid binding protein 2; ATGL; adipose triglyceride lipase; CD36; cluster of differentiation 36; CPT-1; carnitine O-palmitoyltransferase 1; FFA; free
Renoprotective effect of a novel selective PPARα modulator K-877 in db/db mice: A role of diacylglycerol-protein kinase C-NAD(P)H oxidase pathway
Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; AMPK; 5â²-AMP activated protein kinase; CPT-1; carnitine palmitoyltransferase-1; DAG; diacylglycerol; DHE; dihydroethidium; ELISA; enzyme-linked immunosorbent assay; ERR-1α; estrogen-related receptor-1
Oleic acid stimulates glucagon-like peptide-1 release from enteroendocrine cells by modulating cell respiration and glycolysis
Keywords: GLP-1; glucagon like peptide-1; OA; sodium salt of oleic acid; EC; enteroendocrine cells; GPR; G protein-coupled receptors; FAT; fatty acid transporters; CD36; class B scavenger receptor cluster-of-differentiation 36/fatty acid translocase; XF24; Seahorse
Inhibitory effects of Phyllanthus emblica L. on hepatic steatosis and liver fibrosis in vitro
Keywords: α-SMA; alpha-smooth muscle actin; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; CPT-1; carnitine palmitoyl transferase-1; EA; ellagic acid; FAS; fatty acid synthase; FFA; free fatty acid; HSCs; hepatic stellate cells; NAFLD; nonalcohol
α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects
Keywords: α-Lip; α-Lipoic acid; LDH; lactate dehydrogenase; mtDNA; mitochondrial DNA; Sirt1; Sirtuin 1; PGC-1α; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; Nrf1; nuclear respiratory factor 1; Tfam; mitochondrial transcription factor; C
Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes
Keywords: AhR; arylhydrocarbon receptor; BaP; benzo[a]pyrene; NAFLD; non-alcoholic fatty liver disease; TCDD; 2,3,7,8-tetrachlorodibenzodioxin; SDS; sodiumdodecyl-sulfate; CAR; constitutive androstane receptor; PXR; pregnane X receptor; ARNT; aryl hydrocarbon recep
Jinlida granule inhibits palmitic acid induced-intracellular lipid accumulation and enhances autophagy in NIT-1 pancreatic β cells through AMPK activation
Keywords: JLDG; Jinlida granule; TCM; traditional Chinese medicine; ACC; acetyl-coA carboxylase; FAS; fatty acid synthase; CPT-1; carnitine acyl transferase 1; AMPK; AMP activated protein kinase; pAMPK; phospho-AMP activated protein kinase; SREBP-1c; sterol regulat
Youngia denticulata attenuates diet-induced obesity-related metabolic dysfunctions by activating AMP-activated protein kinase and regulating lipid metabolism
Keywords: Youngia denticulata; Obesity; Fatty liver; Lipid accumulation; AMP-activated protein kinase; YDE; Youngia denticulata extract; ACC; acetyl-CoA carboxylase; AMPK; AMP activated protein kinase; SREBP1-c; sterol regulatory element-binding transcription facto
Novel role of TLR4 in NAFLD development: Modulation of metabolic enzymes expression
Keywords: NAFLD; non-alcoholic fatty liver disease; TLR; toll like receptor; LDLrKO; low density lipoprotein receptor knockout; HFD; high fat diet; Apo; apolipoprotein; MTTP; microsomal triglyceride transfer protein; GPAT; glycerol phosphate acyltransferase; ACOX;
The genus Sida L. - A traditional medicine: Its ethnopharmacological, phytochemical and pharmacological data for commercial exploitation in herbal drugs industry
Keywords: ABTS; 2,2â²-azinobis-3-ethylbenzothiazoline-6-sulfonic acid; AGS; human gastric adenocarcinoma; AIU; aspirin induced ulcer; ALP; alkaline phosphatase; ALT; serum alanine aminotransferase; AP; aerial part; APPLIU; aspirin plus pylorus ligation induced ulc
Increased expression of oxidative enzymes in adipose tissue following PPARα-activation
Keywords: ACO; Acyl CoA Oxidase; EAT; Epididymal adipose tissue; CPT-1; Carnitine palmitoyltransferase 1; FFA; free fatty acids; PPARs; peroxisome proliferator-activated receptors; Fenofibrate; Glucose tolerance and epididymal adipose tissue;
Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes
Keywords: PGC-1α; peroxisome proliferator-activated receptor-gamma co-activator 1α; PINK1; PTEN-induced putative kinase 1; AD; Alzheimer disease; PD; Parkinson disease; HD; Huntington disease; ALS; amyotrophic lateral sclerosis; STZ; streptozotocin; HEK; human em
The local corticotropin-releasing hormone receptor 2 signalling pathway partly mediates hypoxia-induced increases in lipolysis via the cAMP-protein kinase A signalling pathway in white adipose tissue
Keywords: Hypoxia; Corticotropin-releasing hormone receptor 2; White adipose tissue; Lipolysis; CRHR2; corticotrophin-releasing hormone receptor type 2; Ucn2; urocortin 2; Ucn3; urocortin 3; WAT; white adipose tissue; BAT; brown adipose tissue; PKA; protein kinase
Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice
Keywords: ACC; acetyl-CoA carboxylase; ACOX; acyl-CoA oxidase; ACS; acyl-CoA synthetase; AK; ankaflavin; ALT; alanine aminotranferase; AMPK; AMP-activated kinase; AST; aspartate transaminase; BSA; bovine serum albumin; CPT-1; carnitine palmitoyl transferase I; CV;
Toxicity generated through inhibition of pyruvate carboxylase and carnitine palmitoyl transferase-1 is similar to high glucose/palmitate-induced glucolipotoxicity in INS-1 beta cells
Keywords: AMPK; AMP-activated protein kinase; CHOP; C/EBP homologous protein; CPT-1; Carnitine palmitate transferase-1; DAG; diacylglycerol; ER; endoplasmic reticulum; Eto; etomoxir; FAO; fatty acid oxidation; HG/PA; high glucose/palmitate; JNK; C-Jun N-terminal ki
Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity
Keywords: α-SA; alpha skeletal actin; Atg3; autophagocytosis associated protein 3; β-MHC; beta myosin heavy chain; CPT-1; carnitine palmitoyl transferase 1; FAO; fatty acid oxidation; GLUT1; glucose transporter 1; GLUT4; glucose transporter 4; HDL; high density l
MDG-1, a polysaccharide from Ophiopogon japonicus, prevents high fat diet-induced obesity and increases energy expenditure in mice
Keywords: Ophiopogon japonicus; Polysaccharide; Anti-obesity; Energy expenditure; Diet induced obesity; Mitochondrial function; T2DM; type 2 diabetes mellitus; HFD; high fat diet; qPCR; quantitative real-time polymerase chain reaction; RER; respiratory exchange rat