Keywords: کانال CRAC; Calcium; Stem cells; Neural development; STIM1; Orai1; CRAC channel
مقالات ISI کانال CRAC (ترجمه نشده)
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CRAC channels as targets for drug discovery and development
Keywords: کانال CRAC; CRAC channel; STIM; Orai; Store-operated calcium entry; Pharmacology; Toxicology; Therapeutics;
ReviewPore opening mechanism of CRAC channels
Keywords: کانال CRAC; SOCE; Calcium; Orai1; STIM1; CRAC channel;
Enamel: Molecular identity of its transepithelial ion transport system
Keywords: کانال CRAC; Hap; hydroxyapatite; NCKX; sodium/calcium/potassium exchanger; SLC; solute carrier; STIM; stromal interaction molecule; SOCE; store-operated Ca2+ entry; CRAC; Ca2+ release activated Ca2+; Enamel; Ion transport; pH; CRAC channel;
Combined immunodeficiency due to a homozygous mutation in ORAI1 that deletes the C-terminus that interacts with STIM 1
Keywords: کانال CRAC; ER; endoplasmic reticulum; STIM1; stromal interaction molecule 1; CRAC channel; calcium release-activated calcium channel; SOCE; store-operated calcium entry; SCID; severe combined immunodeficiency; PHA; phytohemagglutinin; WES; whole exome sequencing; OR
Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells
Keywords: کانال CRAC; CRAC channel; calcium-release-activated calcium channel; CRACR2A; CRAC channel regulator 2A; CRACR2A-L; CRACR2A long; HUVEC; human umbilical vein endothelial cell; Calcium channel; Store-operated calcium entry; G protein; Endothelial cell; Angiogenesis;
Discovery of 7-azaindole derivatives as potent Orai inhibitors showing efficacy in a preclinical model of asthma
Keywords: کانال CRAC; Orai inhibitors; IL-2 inhibitors; LAD2; CRAC channel; OVA model;
The STIM1-ORAI1 microdomain
Keywords: کانال CRAC; STIM1; ORAI1; CRAC channel; Store-operated calcium entry; Microdomain; Calcium;
Inhibition of KCa3.1 by depolarisation and 2-aminoethoxydiphenyl borate (2-APB) during Ca2+ release activated Ca2+ (CRAC) entry in human erythroleukemia (HEL) cells: Implications for the interpretation of 2-APB inhibition of CRAC entry
Keywords: کانال CRAC; 2-APB; Membrane potential; KCa3.1; HEL cells; CRAC channel; Patch clamp; Current clamp; Intracellular Ca2+
The role of CRAC channel in asthma
Keywords: کانال CRAC; Asthma; Lymphocytes; CRAC channel; Orai channels NF-AT; ACQ; asthma control questionnaire; BAL; bronchoalveolar lavage; CRAC; calcium released activated channel; Dex; dexamethasone; ELISA; enzyme linked immunosorbent assay; FEV; forced expiratory volume;
Atomic force microscopy (AFM) imaging suggests that stromal interaction molecule 1 (STIM1) binds to Orai1 with sixfold symmetry
Keywords: کانال CRAC; AFM; atomic force microscopy; CRAC; Ca2+ release-activated Ca2+ channel; ER; endoplasmic reticulum; HA; hemagglutinin; PM; plasma membrane; PAGE; polyacrylamide gel electrophoresis; STIM; stromal interaction molecule; SOAR; STIM1-Orai1 activating region
Mitochondrial regulation of CRAC channel-driven cellular responses
Keywords: کانال CRAC; Mitochondria; CRAC channel; Calcium signal;
Calumin, a Ca2+-binding protein on the endoplasmic reticulum, alters the ion permeability of Ca2+ release-activated Ca2+ (CRAC) channels
Keywords: کانال CRAC; CRAC channel; Ion selectivity; Orai1; STIM1; Patch-clamp; Ca2+ imaging;
ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance
Keywords: کانال CRAC; AICD; activation induced cell death; AIRE; autoimmune regulator; APC; antigen-presenting cell; [Ca2+]i; intracellular Ca2+ concentration; CRAC channel; Ca2+ release-activated Ca2+ channel; CREB; cyclic-AMP-responsive element-binding protein; GALT; gut-ass
Microfluidic formation of single cell array for parallel analysis of Ca2+ release-activated Ca2+ (CRAC) channel activation and inhibition
Keywords: کانال CRAC; Microfluidics; Single cell array; Parallel analysis; CRAC channel;
Activation of store-operated ICRAC by hydrogen peroxide
Keywords: کانال CRAC; Store-operated calcium entry; Orai; CRAC channel; H2O2; Reactive oxygen species; TRPM2 channel;
Mitochondrial regulation of store-operated CRAC channels
Keywords: کانال CRAC; Mitochondria; CRAC channel; Calcium buffering
Novel potent and selective Ca2+ release-activated Ca2+ (CRAC) channel inhibitors. Part 3: Synthesis and CRAC channel inhibitory activity of 4′-[(trifluoromethyl)pyrazol-1-yl]carboxanilides
Keywords: کانال CRAC; Anti-inflammatory; Channel inhibitors; Ca2+ release-activated Ca2+ channel; CRAC channel; Interleukin-2
YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models
Keywords: کانال CRAC; YM-58483; T helper type 2 cytokine; Eosinophilic inflammation; Asthma; CRAC channel
Some assembly required: Constructing the elementary units of store-operated Ca2+ entry
Keywords: کانال CRAC; STIM; Orai; CRACM; Junctional ER; Store-operated calcium entry; CRAC channel; Endoplasmic reticulum
Functional consequences of activating store-operated CRAC channels
Keywords: کانال CRAC; Store-operated entry; CRAC channel; Cell function;
Molecular basis of the CRAC channel
Keywords: کانال CRAC; CRAC channel; T lymphocyte; Store-operated calcium; Stim; Orai;
Novel potent and selective calcium-release-activated calcium (CRAC) channel inhibitors. Part 1: Synthesis and inhibitory activity of 5-(1-methyl-3-trifluoromethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamides
Keywords: کانال CRAC; Anti-inflammatory; Channel inhibitors; Ca2+-release-activated Ca2+ channel; CRAC channel; Interleukin-2; Quantitative structure-activity relationship;
Novel potent and selective calcium-release-activated calcium (CRAC) channel inhibitors. Part 2: Synthesis and inhibitory activity of aryl-3-trifluoromethylpyrazoles
Keywords: کانال CRAC; Anti-inflammatory; Channel inhibitors; Ca2+ release-activated Ca2+ channel; CRAC channel; Interleukin-2; X-ray diffraction studies