Keywords: Immunotherapy; Non-small cell lung cancer; PD-L1; CTLA-4; Ipilimumab; Nivolumab;
مقالات ISI (ترجمه نشده)
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Keywords: Head and neck cancer; Immunotherapy; Monoclonal antibody; STAT; CTLA-4; PD-1; HPV; p53; Cytokine;
Keywords: Oral tolerance; food allergy; mucosal immunology; immunotherapy; regulatory T; CT; Cholera toxin; CTLA-4; Cytotoxic T lymphocyte-associated antigen 4; DBPCFC; Double-blind, placebo-controlled food challenge; DC; Dendritic cell; FoxP3; Forkhead box prote
Keywords: AAV; adeno-associated viruses; Ad6; adenovirus serotype 6; ABCB5Â +; ATP-binding cassette sub-family B member 5; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; APCs; antigen presenting cells; B7.1; (CD80) cluster of differentiation 80; BCG; Ba
Nivolumab-induced alopecia areata: A reversible factor of good prognosis?
Keywords: alopecia areata; anti-programmed cell death protein-1; drug adverse event; immune related; lung cancer; melanoma; nivolumab; AA; alopecia areata; CTLA-4; cytotoxic T-lymphocyte-associated antigen-4; ICI; immune checkpoint inhibitors; PD-1; programmed
HIV-specific CD4+Th17 cells from HIV infected long-term non-progressors exhibit lower CTLA-4 expression and reduced apoptosis
Keywords: HIV; Th17; Exhaustion; Apoptosis; LTNP; CTLA-4;
Detection of high PD-L1 expression in oral cancers by a novel monoclonal antibody L1Mab-4
Keywords: PD-L1; Programmed cell death-ligand 1; PD-1; programmed cell death-1; CBIS; cell-based immunization and screening; SCC; squamous cell carcinoma; ACC; adenoid cystic carcinoma; MEC; mucoepidermoid carcinoma; CTLA-4; cytotoxic T-lymphocyte-associated antige
Analysis of CTLA-4Â +Â 49A/G gene polymorphism in cases with leprosy of Azerbaijan, Northwest Iran
Keywords: Leprosy; CTLA-4; Gene polymorphism; T-ARMS-PCR; Age at the disease onset; Performance status;
Expression of B7-H2 on CD8+ T cells in colorectal cancer microenvironment and its clinical significance
Keywords: MHC; major histocompatibility complex; TCR; T cell receptor; CTLA-4; cytotoxic T lymphocyte associated antigen-4; PD-1; programmed deth-1; PD-L1; programmed deth-1 ligand; TILs; tumor infiltrating lymphocytes; SPF; specific pathogen free; B7-H2; T cells;
Combining radiotherapy and ipilimumab induces clinically relevant radiation-induced abscopal effects in metastatic melanoma patients: A systematic review
Keywords: Abscopal effect; Radiotherapy; Immunotherapy; CTLA-4; Ipilimumab;
Fine tuning subsets of CD4+ T cells by low-dosage of IL-2 and a new therapeutic strategy for autoimmune diseases
Keywords: aa; Amino acids; A region; Acidic region of IL-2Rβ; AKT; Protein kinase B; AA; Alopecia Areata; CTLA-4; Cytotoxic T lymphocyte antigen-4; cDNA; Complementary DNA; Foxp3; Forkhead box P3; GVHD; Chronic graft-versus-host disease; HCV; Hepatitis C virus; hd
Notch signaling pathway dampens tumor-infiltrating CD8+ T cells activity in patients with colorectal carcinoma
Keywords: CCK-8; cell counting kit-8; CTLA-4; cytotoxic T-lymphocyte associated protein-4; DAPT; N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenyl glycinet-butyl ester; FBS; fetal bovine serum; GM-CSF; granulocyte-macrophage colony stimulating factor; IFN-γ; interf
The expression of mCTLA-4 in skin lesion inversely correlates with the severity of psoriasis
Keywords: CTLA4; Cytotoxic T lymphocyte antigen-4; sCTLA-4; soluble Cytotoxic T lymphocyte antigen-4; mCTLA-4; membrane Cytotoxic T lymphocyte antigen-4; IOD; Integrated option density; IMQ; Imiquimod; PASI; psoriasis area and severity index; Treg; regulatory T; CT
PD-1 (PDCD1) Promoter Methylation Is a Prognostic Factor in Patients With Diffuse Lower-Grade Gliomas Harboring Isocitrate Dehydrogenase (IDH) Mutations
Keywords: PD-1; PD-L1; CTLA-4; DNA methylation; Lower-grade glioma; Prognosis;
Combining chemotherapy with PD-1 blockade in NSCLC
Keywords: NSCLC; non-small cell lung cancer; PT-DC; platinum-doublet chemotherapy; ORR; objective response rate; PD-1; programmed cell death-1; PD-L1; programmed death ligand-1; CTLA-4; cytotoxic T-lymphocyte antigen-4; DC; dendritic cell; TME; tumor microenvironme
T-regulatory cells-Triumph of perseverance: The Crafoord Prize for Polyarthritis in 2017
Keywords: Regulatory T cells; Scurfy; IPEX; FoxP3; CTLA-4; Low dose IL-2; Autoimmunity;
Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes
Keywords: Urothelial cancer; Immunotherapy; CTLA-4; Gemcitabine; Cisplatin; Chemotherapy; DNA damage response; DDR; Metastatic;
Regulatory CD4 T cells inhibit HIV-1 expression of other CD4 T cell subsets via interactions with cell surface regulatory proteins
Keywords: Regulatory CD4 T cells; HIV-1; HIV-1 integration; HIV-1 mRNA; CTLA-4; PD-1; GARP;
Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors
Keywords: Cancer immunotherapy; Immune checkpoint blockade; CTLA-4; PD-1; PD-L1;
Molecular adjuvants that modulate regulatory T cell function in vaccination: A critical appraisal
Keywords: ADCC; antibody dependent cell cytotoxicity; CD; cluster of differentiation; mAb; monoclonal antibody; CsA; cyclosporine; CTLA-4; T-lymphocyte antigen 4; GITR; glucocorticoid-induced tumor necrosis factor receptor (TNFR) family related gene; CCR4; C-C chem
microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients
Keywords: miR-125; miR-148; Antitumor Immune Response; Immune Checkpoints; CTL; cytotoxic T lymphocytes; CTLA-4; cytotoxic T lymphocyte associated protein 4; EAC; esophageal adenocarcinoma; gMFI; geometric mean fluorescence intensity; HLA-A/B/C; human leukocyte ant
Epigenetic mechanisms regulating T-cell responses
Keywords: Epigenetics; gene regulation; enhancer; promoter; chromatin accessibility; histone modifications; DNA methylation; transcription factor binding; T-cell development; T-cell function; T-cell exhaustion; regulatory T cells; tissue specificity; ATAC; Assay fo
The mechanism of tumour cell death by metal-based anticancer drugs is not only a matter of DNA interactions
Keywords: 15-LOX-1; 15-lipoxygenase; AIF; apoptosis inducing factor; APC; adenomatous polyposis coli; AKT or PKB; protein kinase B; ATG16L2; autophagy related 16 like 2; AUC; area under the curve; Bad; Bcl-2 associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-
CTLA-4, PD-1 and TIM-3 expression predominantly downregulated in MS patients
Keywords: CTLA-4; PD-1; TIM-3; Multiple sclerosis;
Immunomodulatory effects of BRAF and MEK inhibitors: Implications for Melanoma therapy
Keywords: Binimetinib (PubChem CID: 10288191); Cobimetinib (PubChem CID: 16222096); Dabrafenib (PubChem CID: 44462760); Encorafenib (PubChem CID: 50922675); Trametinib (PubChem CID: 11707110); Vemurafenib (PubChem CID: 42611257); ATC; adoptively transferred T cells
Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity
Keywords: CTLA-4; CD28; Immunodeficiency; Autoimmunity; Mutation; Regulatory T cells;
TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells
Keywords: APC; antigen-presenting cell; BMDCs; bone marrow-derived dendritic cells; CFSE; carboxyfluorescein succinimidyl ester; CTL; cytotoxic T lymphocyte; CTLA-4; cytotoxic T lymphocyte-associated antigen-4; DCs; dendritic cells; ERK; extracellular-signal-regula
Cross-talk between EGFR and IL-6 drives oncogenic signaling and offers therapeutic opportunities in cancer
Keywords: EGFR; epidermal growth factor receptor; IL-6; interleukin 6; ADC; antibody-drug conjugate; HGF; hepatocyte growth factor; c-met/MET; tyrosine-protein kinase Met; CTLA-4; cytotoxic T-lymphocyte-associated protein 4; VEGF; vascular endothelial growth factor
Pediatric-onset Evans syndrome: Heterogeneous presentation and high frequency of monogenic disorders including LRBA and CTLA4 mutations
Keywords: Autoimmune cytopenias; Immune checkpoint deficiencies; Extensive genetic screening; LRBA and CTLA-4 deficiencies; ES; Evans syndrome; AIHA; Autoimmune hemolytic anemia; ITP; Immune thrombocytopenia; ALPS; Autoimmune lymphoproliferative syndrome; CTLA-4; C
Rationale for combination of therapeutic antibodies targeting tumor cells and immune checkpoint receptors: Harnessing innate and adaptive immunity through IgG1 isotype immune effector stimulation
Keywords: ADCC; Cetuximab; CTLA-4; PD-L1; PD-1; Immunotherapy;
Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy
Keywords: Cancer immunotherapy; CTLA-4; Hybrid nanoparticles; Imatinib; tLyp1 peptide; Treg cell;
Implications of uterine NK cells and regulatory T cells in the endometrium of infertile women
Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; ART; assisted reproductive technology; dNK cells; decidual natural killer cells; CTLA-4; cytotoxic T-lymphocyte antigen-4; EVT; extra-villous trophoblast; G-CSF; granulocyte colony-stimulating factor; G
Revealing the atomistic details behind the binding of B7-1 to CD28 and CTLA-4: A comprehensive protein-protein modelling study
Keywords: Immune checkpoints; CD28; B7-1; CTLA-4; Protein-protein docking; Molecular dynamics;
Dendritic cells conditioned by activin A-induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma
Keywords: Activin-A; allergic asthma; regulatory T cells; tolerogenic dendritic cells; immune regulation; Act-A-Treg; Activin-A-induced regulatory T; alum; Aluminum hydroxide; BAL; Bronchoalveolar lavage; BM-DCs; Bone marrow-derived dendritic cell; cDC; Convent
Redox control of cancer cell destruction
Keywords: ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r
Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review
Keywords: AAV; antineutrophil cytoplasmic antibody associated vasculitis; ACE; angiotensin-converting enzyme; Agt; angiotensin; ANCA; antineutrophil cytoplasmic antibody; AT1R; angiotensin II receptor type 1; AT2R; angiotensin II receptor type 2; CCL2; chemokine C-
DNA mismatch repair in cancer
Keywords: 5-FU; 5-fluorouracil; bMMRD; Biallelic mismatch repair deficiency; CD28; cluster of differentiation 28; CIN; Chromosomal instable; CR; complete response; CRC; colorectal cancer; CTL; cytotoxic T-lymphocytes; CTLA-4; cytotoxic T lymphocyte antigen-4; DFS;
The role of T cells in the pathogenesis of Parkinson's disease
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APC; antigen-presenting cell; AQP4; Aquaporin-4; BBB; blood-brain barrier; BCL6; B cell lymphoma 6; BCR; B cell receptor; BEC; brain endothelial cells; CCL20; C-C motif ligand 20; CCR2; C-C
CD25-expressing Th17 cells mediate CD8+ T cell suppression in CTLA-4 dependent mechanisms in pancreatic ductal adenocarcinoma
Keywords: CD25; CTLA-4; Pancreatic cancer; Th17;
Combined blockade of Tim-3 and MEK inhibitor enhances the efficacy against melanoma
Keywords: Trametinib; Tim-3; MAPK pathway; Targeted therapy; Cancer immunotherapy; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated extracellular signal-regulated kinase; OS; overall survival; CTLA-4; cytotoxic T lymphocyte antigen-4; PD-1; programmed
Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization
Keywords: TCI; transcutaneous immunization; CTL; cytotoxic T-cell; TLR7; toll-like receptor 7; CTLA-4; cytotoxic T-lymphocyte associated antigen 4; s.c; subcutaneous; i.p.; intraperitoneal; Treg; regulatory T-cell; IFN; interferon; IL; interleukin; APC; antigen pre
Immuno-oncology and Its Opportunities for Interventional Radiologists: Immune Checkpoint Inhibition and Potential Synergies with Interventional Oncology Procedures
Keywords: APC; antigen-presenting cell; CTLA-4; cytotoxic T-lymphocyte antigen-4; DC; dendritic cell; HCC; hepatocellular carcinoma; HIF-1α; hypoxia-inducible factor-1α; MDSC; myeloid-derived suppressor cell; PD-1; programmed death-1; PDL; programmed death ligand
Functional polymorphisms in PD-L1 gene are associated with the prognosis of patients with early stage non-small cell lung cancer
Keywords: PD-L1; PD-1 ligand; NSCLC; non-small cell lung cancer; SNPs; single nucleotide polymorphisms; PD-1; programed cell death-1; CTLA-4; cytotoxic T lymphocyte-associated antigen 4; OS; overall survival; IHC; immunohistochemistry; HRs; hazard ratios; HWE; Hard
Epigenetic alterations in chronic disease focusing on Behçet's disease: Review
Keywords: ncRNAs; non-coding RNAs; BD; Behçet's disease; MHC; major histocompatibility complex; HLA; Human Leukocyte Antigen; TNF; Tumor Necrosis Factor; IL-10; interleukin-10; MEFV; Mediterranean fever; TH1; T-helper 1; Me5C; 5-methyl cytosine; DNMTs; DNA methy
PD-1, PD-L1 and CTLA-4 in pregnancy-related - and in early-onset breast cancer: A comparative study
Keywords: Pregnancy-related breast cancer; Young women with breast cancer; Prognosis; PD-1; PD-L1; CTLA-4;
Immunothérapie et cancer du poumon : où en sommes-nous ?
Keywords: Cancer du poumon; Immunité anticancéreuse; Anti-PD1; Anti-PD-L1; Vaccins anti-tumoraux; CTLA-4; Biomarqueurs; Lung cancer; Antitumor immunity; PD-L1 expression; PD1 inhibitors; PD-L1 inhibitors; Anti-tumor vaccines; CTLA-4; Biomarkers;
CAR T-cell therapy for lung cancer and malignant pleural mesothelioma
Keywords: ACT; adoptive cell therapy; ADC; adenocarcinoma; ALK; anaplastic lymphoma kinase; CAF; cancer-associated fibroblast; CAR; chimeric antigen receptor; CEA; carcinoembryonic antigen; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DNR; dominant negative
Adjuvanticity of a CTLA-4 3â² UTR complementary oligonucleotide for emulsion formulated recombinant subunit and inactivated vaccines
Keywords: Adjuvant; Oligonucleotide; CTLA-4; 3â² UTR; Vaccine;
Immune Checkpoint Molecule, VISTAÂ Regulates T-Cell-Mediated Skin Inflammatory Responses
Keywords: APC; antigen-presenting cell; CTLA-4; cytotoxic T-lymphocyte-associated Ag-4; DC; dendritic cell; mAb; monoclonal antibody; PD-1; programmed death-1; Treg; regulatory T cell; VISTA; V-domain Ig suppressor of T-cell activation;
Impact of chemotherapy-induced neutropenia (CIN) and febrile neutropenia (FN) on cancer treatment outcomes: An overview about well-established and recently emerging clinical data
Keywords: ABCC1/MRP; ATP binding cassette subfamily C member 1/ multidrug resistance protein; ABVD; doxorubicine-bleomycin-vinblastine-dacarbazine; AC; doxorubicin-cyclophosphamide; ANC; absolute neutrophil count; ASCO; American Society of Clinical Oncology; AUC; a