Activation profile of CXCL8-stimulated neutrophils and aging
Keywords: Elderly; CXCL8; Neutrophils; Antimicrobial enzymes;
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CXCL8 in thyroid disease: From basic notions to potential applications in clinical practice
Keywords: Thyrocytes; Chemokines; CXCL8; Thyroid cancer; Autoimmune thyroid disease;
Lipopolysaccharide-binding Protein Inhibits Toll-like Receptor 2 Activation by Lipoteichoic Acid in Human Odontoblast-like Cells
Keywords: CD14; CXCL8; human dental pulp; IL-6; innate immunity; LBP; NF-κB; pathogen-associated molecular pattern; p38; Toll-like receptor
Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres
Keywords: Nasopharyngeal carcinoma; Tumour spheres; MIF; CXCL8; CXCR2
Potentiation of Inflammatory CXCL8 Signalling Sustains Cell Survival in PTEN-deficient Prostate Carcinoma
Keywords: Inflammation; Apoptosis; CXCL8; CXCR2; Hypoxia; Prostate cancer; PTEN
Nuclear factor kappa B (NF-κB): A novel cause for diabetes, coronary artery disease and cancer initiation and promotion?
Keywords: CAD; coronary artery disease; CAN; cancer; BMI; body mass index; ACS; acute coronary syndrome; NF-κB; nuclear factor kappa B; VCAM-1; vascular cell adhesion molecule-1; MCP-1; monocyte chemoattractantprotein-1; JUPITER; justification for the use of stati
Combined effects of CXCL8 and CXCR2 gene polymorphisms on susceptibility to systemic sclerosis
Keywords: Receptor; CXCR2; CXCL8; Scleroderma; Systemic;
A novel role for the Rho-associated kinase, ROCK, in IL-1-stimulated intestinal epithelial cell responses
Keywords: FN; fibronectin; GAPD; glyceraldehyde-3-phosphate dehydrogenase; IBD; inflammatory bowel disease; IEC; intestinal epithelial cell; IKK; IκB kinase; IL; interleukin; ITS; insulin, transferrin, selenium; RI; Y27632 ROCK inhibitor; IL-1; Intestinal epitheli
Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells
Keywords: Bladder cancer; Arsenic; Monomethylarsonous acid; IL-8,; CXCL8; CXCR1; Inflammation
Corticosteroid insensitivity of chemokine expression in airway smooth muscle of patients with severe asthma
Keywords: Airway smooth muscle; asthma; corticosteroid insensitivity; CX3CL1; CCL11; CXCL8; ASMC; Airway smooth muscle cell; ChIP; Chromatin immunoprecipitation; ERK; Extracellular signal-regulated kinase; GR; Glucocorticoid receptor; JNK; c-Jun N-terminal kinase;
Serum chemokine levels and developmental outcome in preterm infants
Keywords: FIRS; fetal inflammatory response syndrome; IL; interleukin; TNF; tumor necrosis factor; CP; cerebral palsy; CNS; central nervous system; CC; correlation coefficient; MCP; monocyte chemoattractant protein; VLBW; very low birth weight; AGA; appropriate-for
Targeting of a common receptor shared by CXCL8 and N-Ac-PGP as a therapeutic strategy to alleviate chronic neutrophilic lung diseases
Keywords: N-Ac-PGP; CXCL8; Neutrophil; CXCR1/2
CXCL8 protects human neurons from amyloid-β-induced neurotoxicity: Relevance to Alzheimer's disease
Keywords: MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DAPI; 4â²,6-diamidino-2-phenylindole; AD; Alzheimer's disease; Aβ; amyloid-β; BDNF; brain-derived neurotrophic factor; CNND; Center for Neurovirology and Neurodegenerative Disorders;
CXCL8 attenuates chemoattractant-induced equine neutrophil migration
Keywords: Equine neutrophils; Migration; Adherence; CXCL8; cAMP
N-acetylated Proline–Glycine–Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release
Keywords: N-ac-PGP; Chemotaxis; Neutrophil; Chronic airway inflammation; CXCL8
A CXCL8 receptor antagonist based on the structure of N-acetyl-proline-glycine-proline
Keywords: Inflammation; d-peptide; CXCL8; NAc-PGP; CXCR1; CXCR2
CXCL8 of Scophthalmus maximus: Expression, biological activity and immunoregulatory effect
Keywords: CXCL8; Interleukin-8; Scophthalmus maximus; Inflammation;
Pneumolysin-induced CXCL8 production by nasopharyngeal epithelial cells is dependent on calcium flux and MAPK activation via Toll-like receptor 4
Keywords: Chemokine; Streptococcus pneumoniae; Pneumolysin; CXCL8; Toll-like receptor 4;
Heat-killed Enterococcus faecalis Alters Nitric Oxide and CXCL12 Production but not CXCL8 and CCL3 Production by Cultured Human Dental Pulp Fibroblasts
Keywords: CCL3; chemokines; CXCL8; CXCL12; dental pulp fibroblasts; Enterococcus faecalis; innate immunity; nitric oxide; pulpitis
IL-17 primes airway epithelial cells lacking functional Cystic Fibrosis Transmembrane conductance Regulator (CFTR) to increase NOD1 responses
Keywords: Interleukin; Bacteria; Lung; Inflammation; Signal transduction; Receptors; AECs; airway epithelial cells; CF; cystic fibrosis; CFTR; CF transmembrane conductance regulator; CIKS; Connection to IκB Kinase and Stress-activated protein kinase; CXCL8; Cyst-X
Cellular factors involved in CXCL8 expression induced by glycated serum albumin in vascular smooth muscle cells
Keywords: CXCL8; Glycated serum albumin; Toll-like receptor; Vascular smooth muscle cell;
Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α
Keywords: IL-1β; HIF-1α; CXCL8; Cell migration; Breast cancer;
Pneumococcal proteins PspA and PspC induce CXCL8 production in human neutrophils: implications in pneumococcal infections
Keywords: Streptococcus pneumoniae; Protein; Neutrophil; CXCL8;
A novel CXCL8 protein-based antagonist in acute experimental renal allograft damage
Keywords: Inflammation; Acute rejection; Ischemia-reperfusion injury; Chemokine; CXCL8; Proteoglycan; Kidney transplantation;
Identification of a novel compound that stimulates intracellular calcium increase and CXCL8 production in human neutrophils from Schisandra chinensis
Keywords: Schisandra chinensis; Neutrophils; α-iso-cubebene (a novel compound); Calcium increase; CXCL8
Ovine trophoblast is a primary source of TNFα during Chlamydophila abortus infection
Keywords: Trophoblast; Chlamydophila abortus; TNFα; CXCL8; Infectious abortion
Similar colds in subjects with allergic asthma and nonatopic subjects after inoculation with rhinovirus-16
Keywords: Asthma; viral respiratory tract infections; virus-induced asthma; rhinovirus; eosinophil; CCL2; CXCL8; total serum IgE; allergy; common cold; PEF; Peak expiratory flow; PFU; Plaque-forming units; RV16; Rhinovirus-16; TCID50; 50% Tissue culture infective d
Prostaglandin F2α-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway
Keywords: PGF2α; FP receptor; Chemokine; Calcineurin; Prostaglandin; CXCL8;
Cross talk Initiated by Endothelial Cells Enhances Migration and Inhibits Anoikis of Squamous Cell Carcinoma Cells through STAT3/Akt/ERK Signaling
Keywords: CM; conditioned medium; CXCL8; interleukin-8; EBM; endothelial cell basal medium; EGF; epidermal growth factor; ERK; extracellular signal-regulated kinase; HDMEC; human dermal microvascular endothelial cell; HNSCC; head and neck squamous cell carcinoma; I
ERα-negative and triple negative breast cancer: Molecular features and potential therapeutic approaches
Keywords: Breast cancer; CXC chemokine; CXCL8; ERα; ERβ; Estrogen carcinogenesis; GRCP-30/EGFR; microRNAs; Therapeutic approaches for TN-breast cancer; Triple negative breast cancer;
Growth-Inhibitory and Antiangiogenic Activity of the MEK Inhibitor PD0325901 in Malignant Melanoma with or without BRAF Mutations
Keywords: MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; MEK; MAPK/ERK kinase; VEGF; vascular endothelial growth factor; HIF; hypoxia-inducible factor; CXCL8; interleukin 8;
Interleukin-8 Is Increased in Gingival Crevicular Fluid from Patients with Acute Pulpitis
Keywords: CXCL8; gingival crevicular fluid; irreversible pulpitis; neurogenic inflammation; pain; TNF-α
The other side of the medal: How chemokines promote analgesia
Keywords: CFA; complete Freund's adjuvant; CCL2, MCP-1; monocyte chemoattractant protein 1; CCL3, MIP-1α; macrophage inflammatory protein-1α; CXCL1, KC; keratinocyte derived chemokine; CXCL2/3, MIP-2; macrophage inflammatory protein-2; CXCL8; interleukin-8; DRG;
Mycobacterium bovis BCG Toll-Like Receptors 2 and 4 Cooperation Increases the Innate Epithelial Immune Response
Keywords: CXCL8; MAPK; Mycobacterium bovis; TLR2; TLR4
Chemokine CXCL8 modulates GluR1 phosphorylation
Keywords: CXCL8; Phosphorylation; Glutamate receptor; Chemotaxis
A new protocol for high-yield purification of recombinant human CXCL8(3–72)K11R/G31P expressed in Escherichia coli
Keywords: CXCL8; Antagonist; Expression; Purification; Lipopolysaccharide; Endotoxin
HIV-1-infected and/or immune-activated macrophages regulate astrocyte CXCL8 production through IL-1β and TNF-α: Involvement of mitogen-activated protein kinases and protein kinase R
Keywords: CXCL8; Astrocyte; Macrophage; Inflammation; HIV-1 associated dementia
Intracellular cross-talk between the GPCR CXCR1 and CXCR2: Role of carboxyl terminus phosphorylation sites
Keywords: CXCR1; CXCR2; CXCL8; G protein-coupled receptors; Internalization; Phosphorylation
Mycobacterium bovis bacillus Calmette–Guérin (BCG)-induced CXCL8 production is mediated through PKCα-dependent activation of the IKKαβ signaling pathway in epithelial cells
Keywords: CXCL8; Epithelial cells; IKKαβ; Mycobacterium bovis; PKCα
Description of a fugu CXC chemokine and two CXC receptor genes, and characterization of the effects of different stimulators on their expression
Keywords: CXCL8; CXCR; Genomic organization; Gene expression; Stimulation
In vitro infection of human dendritic cells by Aspergillus fumigatus conidia triggers the secretion of chemokines for neutrophil and Th1 lymphocyte recruitment
Keywords: CXCL8; CCL20; CCL19; Cell recruitment; Fungus
Synthesis and structure–activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists
Keywords: CXCR2; CXCR1; Cyclobutenedione; Squarate; 3,4-Diaminocyclobut-3-ene-1,2-dione; IL-8; CXCL8; Chemokine; Neutrophil
Chemokine Concentrations and Mast Cell Chemotactic Activity in BAL Fluid in Patients With Eosinophilic Bronchitis and Asthma, and in Normal Control Subjects
Keywords: CCL11; CCR3; chemokine receptor; CXCL8; CXCL10; CXCR1; CXCR3;
Neurocysticercal antigens stimulate chemokine secretion from human monocytes via an NF-κB-dependent pathway
Keywords: Cysticercosis; CXCL8; CCL2; Toll-like receptor; NF-κB; Monocyte
CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: Cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner
Keywords: CXCL8; CXCR1; CXCR2; Focal adhesion kinaseCD, Cytochalasin D; DMSO, Dimethyl Sulfoxide; ECM, Extracellular Matrix; FAK, Focal Adhesion Kinase; GPCR, G Protein-Coupled Receptor; HEK, Human Embryonal Kidney; HPF, High Power Field; MT, Microtubules; Noc, Noc
Urinary interleukin-8 is elevated in urinary tract infections independently of the causative germs
Keywords: IL-8; CXCL8; Urinary tract infection; Innate immunity; Infectious marker; Early diagnosis;
CXCL8 modulates human intestinal epithelial cells through a CXCR1 dependent pathway
Keywords: Chemokines; Epithelial cells; CXCL8; Interleukin-8; Wound healing; Transforming growth factor β; DMEM; Dulbecco's Modified Eagle's Medium; DMSO; dimethyl sulfoxide; FCS; fetal calf serum; MTT; 3(4,5-dimethylthiazolyl-2)-2,5-diphenyl tetrazolium bromide;
Mycobacterium bovis BCG induces CXC chemokine ligand 8 secretion via the MEK-dependent signal pathway in human epithelial cells
Keywords: CXCL8; Epithelial cells; Mycobacterium bovis; MEK; p38 MAP kinase;
The activation of IL-8 receptors in cultured guinea pig Müller glial cells is modified by signals from retinal pigment epithelium
Keywords: Müller cell; Glia; CXCL8; CXCR1; CXCR2; Chemokine; Guinea pig;
Perspectives for cytokine antagonist therapy in COPD
Keywords: Drug Discovery; Pharmaceutical Science; Biochemistry; Chemical Biology; Tumor necrosis factor-alpha; Signal transduction; Transcription; CCL2; CCR2; CXCL8; CXCR2;