Preparation, evaluation and optimization of nanoparticles composed of thiolated triethyl chitosan: A potential approach for buccal delivery of insulin
Keywords: Insulin nanoparticles; Thiolated chitosan; Box-Behnken response surface methodology; Buccal drug delivery; Cys; L-cysteine; TEC; triethyl chitosan; TEC-Cys; thiolated N-triethyl chitosan; NMP; N-methyl pyrrolidone; NHS; N-hydroxysuccinimide; DTNB; 5, 5â²