Keywords: فعالیت سیتواستاتیک; 3-Deazapurines; 7-Deazapurines; 9-Deazapurines; l-Ascorbic acid; Imino-l-ascorbic acid; Cytostatic activity; Antiviral activity
مقالات ISI فعالیت سیتواستاتیک (ترجمه نشده)
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Keywords: فعالیت سیتواستاتیک; Ferrocene; Cinchona; 1,2,3-Triazole; Click reaction; Cytostatic activity
Synthesis, molecular modeling and biological evaluation of potent analogs of 2-methoxyestradiol
Keywords: فعالیت سیتواستاتیک; 2-Methoxyestradiol; Cytostatic activity; Anti-angiogenic effects; Tubulin inhibition; Anti-cancer agents; Friedel-Crafts alkylation;
Hydroalcoholic extract of the widely used Mexican plant Justicia spicigera Schltdl. exerts a cytostatic effect on LNCaP prostate cancer cells
Keywords: فعالیت سیتواستاتیک; HJsE; hydroalcoholic J. spicigera extract; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; TLC; thin-layer chromatography; RPMI-1640; Roswell Park Memorial Institute medium 1640; PBS; phosphate-buffered saline; DMSO; dimethylsulfoxide;
Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole-coumarin hybrids
Keywords: فعالیت سیتواستاتیک; 1,2,3-triazole-coumarin hybrids; Click chemistry; Cytostatic activity; Antibacterial activity; 5-Lipoxygenase (5-LO); Acid ceramidase (ASAH);
Novel organotin complexes containing the 2,2′-bipyridine-3,3′,6,6′-tetracarboxylate. Helical supramolecular structure and cytostatic activity
Keywords: فعالیت سیتواستاتیک; Dibutyltin; Tributyltin; 2,2′-bipyridine-3,3′,6,6′-tetracarboxylate; AMP; Cytostatic activity; X-ray structurebptcH4, 2,2′-bipyridine-3,3′,6,6′-tetracarboxylic acid; AMP, adenosine 5′-monophosphate, 5′-adenylic acid; Bu, n-butyl
Investigation of fatty acid conjugates of 3,5-bisarylmethylene-4-piperidone derivatives as antitumor agents and human topoisomerase-IIα inhibitors
Keywords: فعالیت سیتواستاتیک; Curcumin analogs; Fatty acid amides; 3,5-Bisarylmethylene-4-piperidones; Michael acceptor; Anti-oxidant; Cytostatic activity; Topoisomerase IIα inhibitors; QSAR
Curcumin-inspired cytotoxic 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors
Keywords: فعالیت سیتواستاتیک; Curcumin analogs; 4-Piperidones; Maleamic acids; Cytostatic activity; QSAR; Topoisomerase IIα inhibition
3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties
Keywords: فعالیت سیتواستاتیک; Harmine derivatives; Antiproliferative activity; Cytostatic activity; Comparative molecular field analysis;
A novel and easy two-step, microwave-assisted method for the synthesis of halophenyl pyrrolo[2,3-b]quinoxalines via their pyrrolo precursors. Evaluation of their bioactivity
Keywords: فعالیت سیتواستاتیک; Pyrroloquinoxaline; Pyrrolidine; Multicomponent reaction; Antioxidant activity; Antiviral activity; Cytostatic activity;
All trans 1-(3-arylacryloyl)-3,5-bis(pyridin-4-ylmethylene)piperidin-4-ones as curcumin-inspired antineoplastics
Keywords: فعالیت سیتواستاتیک; Curcumin; Michael acceptor; Anti-oxidant; Cytostatic activity; Topoisomerase II inhibitors; QSAR;
Novel semicarbazides and ureas of primaquine with bulky aryl or hydroxyalkyl substituents: Synthesis, cytostatic and antioxidative activity
Keywords: فعالیت سیتواستاتیک; Primaquine; Urea; Semicarbazide; Cytostatic activity; Antioxidative activityAAPH, 2,2′-azobis(2-amidinopropane) hydrochloride; BtcCl, 1-benzotriazole carboxylic acid chloride; BtH, 1H-benzo[d][1,2,3]triazole; CEM, acute lymphoblastic leukemia; CYP-1, cyto
Butyltin(IV) 2-sulfobenzoates: Synthesis, structural characterization and their cytostatic and antibacterial activities
Keywords: فعالیت سیتواستاتیک; Butyltin 2-sulfobenzoates; Dibutyltin; Tributyltin; Cytostatic activity; Antibacterial activity
Antiproliferative steroidal glycosides from Digitalis ciliata
Keywords: فعالیت سیتواستاتیک; Digitalis ciliata; Steroidal glycosides; Antiproliferative activity; Cytostatic activity;
Novel NSAID 1-acyl-4-cycloalkyl/arylsemicarbazides and 1-acyl-5-benzyloxy/hydroxy carbamoylcarbazides as potential anticancer agents and antioxidants
Keywords: فعالیت سیتواستاتیک; NSAID; Semicarbazide; Carbazide; Cytostatic activity; Lipoxygenase; Lipid peroxidation;
A dinuclear silver compound with 5,6,7-trimethyl-[1,2,4]triazolo[1,5-a]pyrimidine with a short Ag-Ag bond. Synthesis, characterization, single-crystal structure analysis and cytostatic activity
Keywords: فعالیت سیتواستاتیک; Silver; Cytostatic activity; Triazolopyrimidine;
Facile transformation of Biginelli pyrimidin-2(1H)-ones to pyrimidines. In vitro evaluation as inhibitors of Mycobacterium tuberculosis and modulators of cytostatic activity
Keywords: فعالیت سیتواستاتیک; Biginelli compounds; Pyrimidines; Tuberculosis; MABA; Inhibitors; Cytostatic activity;
Synthesis and cytostatic activity of purine nucleosides derivatives of allofuranose
Keywords: فعالیت سیتواستاتیک; Allofuranose; Cancer; Cytostatic activity; Hexofuranosyl nucleosides; Purine
The unsaturated acyclic nucleoside analogues bearing a sterically constrained (Z)-4′-benzamido-2′-butenyl moiety: Synthesis, X-ray crystal structure study, cytostatic and antiviral activity evaluations
Keywords: فعالیت سیتواستاتیک; Unsaturated acyclic nucleoside analogues; X-ray diffraction; Supramolecular self-assembling; Cytostatic activity; Antiviral activity
Synthesis and anticancer activity evaluation of 2(4-alkoxyphenyl)cyclopropyl hydrazides and triazolo phthalazines
Keywords: فعالیت سیتواستاتیک; Cinnamic acid; Cyclopropyl backbone; Anticancer; Cytostatic activity; Apoptosis-resistant;
Design, synthesis and bioevaluation of novel maleamic amino acid ester conjugates of 3,5-bisarylmethylene-4-piperidones as cytostatic agents
Keywords: فعالیت سیتواستاتیک; 3,5-Bisarylmethylene-4-piperidones; Cytostatic activity; Anticancer; Topoisomerase inhibitions; QSAR
Tetrameric 1:1 and monomeric 1:3 complexes of silver(I) halides with tri(p-tolyl)-phosphine: A structural and biological study
Keywords: فعالیت سیتواستاتیک; Bioinorganic chemistry; Silver(I) complexes; Tri(p-tolyl)phosphine; Crystal structures; Cytostatic activity
The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: Synthesis, cytostatic and antiviral activity evaluations
Keywords: فعالیت سیتواستاتیک; Nonsteroidal anti-inflammatory drugs (NSAID); 3-Hydroxypropylamides; Phosphoramidates; Cytostatic activity
Sodium and potassium benzeneazophosphonate complexes with crown ethers: Solid-state microwave synthesis, characterization and biological activity
Keywords: فعالیت سیتواستاتیک; Crown ether; Sodium; Potassium; Benzeneazophosphonate complex; Cytostatic activity; Antiviral activity
Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides
Keywords: فعالیت سیتواستاتیک; Purines; Nucleosides; Conjugate additions; Cytostatic activity
Cytostatic evaluations of nucleoside analogs related to unnatural base pairs for a genetic expansion system
Keywords: فعالیت سیتواستاتیک; Unnatural base pairs; Base analogs; Cytostatic activity; Nucleoside analogs; Antitumor drug
Cytostatic activity of novel 4′-aminochalcone-based imides
Keywords: فعالیت سیتواستاتیک; Chalcone; Maleimides; Cytostatic activity; Thiol-alkylators; QSAR
Design, synthesis, and cytostatic activity of novel cyclic curcumin analogues
Keywords: فعالیت سیتواستاتیک; Curcumin analogues; Cytostatic activity; Anticancer; QSAR; Anti-oxidant
Synthesis and in vitro antitumoral activity of new 3,5-dicyanopyridine derivatives
Keywords: فعالیت سیتواستاتیک; Pyridines; Dicyanopyridines; Anticancer activity; Cytostatic activity
E,E,E-1-(4-Arylamino-4-oxo-2-butenoyl)-3,5-bis(arylidene)-4-piperidones: A topographical study of some novel potent cytotoxins
Keywords: فعالیت سیتواستاتیک; 3,5-Bis(arylidene)-4-piperidones; Cytostatic activity; Molecular modeling; Human N-myristoyltransferase; Murine toxicity
Limitations of the Wittig-Horner-type annulation of fluorobutenolide moiety to 3-hydroxyquinoline-2,4(2H,3H)-diones. Novel modifications of the Perkow reaction including fluorinated acyloxy leaving groups
Keywords: فعالیت سیتواستاتیک; Wittig-Horner synthesis; Lithium 2-(diethoxyphosphoryl)-2-fluoroacetate; 3-Halogenoacyloxyquinoline-2,4(1H,3H)-diones; Fluorofuranone; But-2-enolide, Perkow reaction; 19F NMR reaction profile; Cytostatic activity; Chronic myeloid leukemia; Breast carcin
4-Methylideneisoxazolidin-5-ones—A new class of α-methylidene-γ-lactones with high cytostatic activity
Keywords: فعالیت سیتواستاتیک; α-Methylidene-β-lactones; Isoxazolidin-5-ones; Cytostatic activity; Horner–Wadsworth–Emmons olefination
Synthesis and biological activity of tricyclic analogues of 9-{[cis-1′,2′-bis(hydroxymethyl)cycloprop-1′-yl]methyl}guanine
Keywords: فعالیت سیتواستاتیک; A-5021; Tricyclic analogues; Synthesis; Fluorescence; Anti-VZV activity; Anti-HSV-1; HSV-2 activity; Cytostatic activity
Synthesis, structural studies, and cytostatic evaluation of 5,6-di-O-modified l-ascorbic acid derivatives
Keywords: فعالیت سیتواستاتیک; l-Ascorbic acid; Configurational analysis; Conformational analysis; Single crystal X-ray diffraction; Cytostatic activity
Synthesis, X-ray crystal structural study, antiviral and cytostatic evaluations of the novel unsaturated acyclic and epoxide nucleoside analogues
Keywords: فعالیت سیتواستاتیک; Olefinic nucleoside analogues; Epoxide purine derivatives; Cytostatic activity; Anti-HIV-1 activity;
1,4,9,10-Anthradiquinone as precursor for antitumor compounds
Keywords: فعالیت سیتواستاتیک; Ring enlargement; Nenitzescu reaction; Quinones; Enamines, Azonine; Cytostatic activity
Fluorosubstitution and 7-alkylation as prospective modifications of biologically active 6-aryl derivatives of tricyclic acyclovir and ganciclovir analogues
Keywords: فعالیت سیتواستاتیک; Cytostatic activity; HSV-1 TK gene therapy; Tricyclic acyclovir analogues; Fluorosubstitution; Anti-HSV-1, HSV-2 activity
Synthesis and antiproliferative activity of 2,6-Dibenzylamino-3,5-dicyanopyridines on human cancer cell lines
Keywords: فعالیت سیتواستاتیک; Pyridines; Dicyanopyridines; Anticancer activity; Cytostatic activity;
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation
Keywords: فعالیت سیتواستاتیک; Pyrimidine and purine derivatives of l-ascorbic acid; E and Z isomers; Cytostatic activity; Antiviral activity; Apoptosis;