The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation

Novel C-5 substituted pyrimidine (6-15) and purine (18-20) derivatives of l-ascorbic acid containing free hydroxy groups at C-2′ or C-2′ and C-3′ positions of the lactone ring were synthesized and evaluated for their cytostatic and antiviral activities.