Four new quassinoids from the roots of Eurycoma longifolia Jack
Keywords: فعالیت سیتوتوکسیک; Quassinoids; Cytotoxic activity; Single crystal X-ray diffraction
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Chemical composition, anti-inflammatory activity and cytotoxic activity of the liposoluble constituents from different parts of Acanthopanax evodiaefolius by the Herbal Blitzkrieg Extractor
Keywords: فعالیت سیتوتوکسیک; Acanthopanax evodiaefolius; Liposoluble constituents; Herbal Blitzkrieg Extractor; Anti-inflammatory; Cytotoxic activity; Nitric oxide
Polyketides from the mangrove-derived endophytic fungus Acremonium strictum
Keywords: فعالیت سیتوتوکسیک; Acremonium strictum; Cytotoxic activity; Endophytic fungus; Polyketides; Rhizophora apiculata;
Physalins and withanolides from the fruits of Physalis alkekengi L. var. franchetii (Mast.) Makino and the inhibitory activities against human tumor cells
Keywords: فعالیت سیتوتوکسیک; Physalis alkekengi L. var. franchetii (Mast.) Makino; Steroids; Structural identification; Cytotoxic activity;
Topoisomerase II inhibitors from the roots of Stellera chamaejasme L.
Keywords: فعالیت سیتوتوکسیک; BYRNGJPMZGEDAM-PYKMWLBDSA-NStellera chamaejasme L.; Cytotoxic activity; Topoisomerase II; Apoptosis
New triterpene saponins from the seed cake of Camellia Oleifera and their cytotoxic activity
Keywords: فعالیت سیتوتوکسیک; New triterpene saponins; Seed cake of Camellia oleifera Abel.; Cytotoxic activity;
Phenolic compounds from Dalbergia odorifera
Keywords: فعالیت سیتوتوکسیک; Leguminosae; Dalbergia odorifera T. Chen; Phenolic compounds; Cytotoxic activity; Antibacterial activity;
Sesterterpenoids and other constituents from Salvia lachnocalyx Hedge
Keywords: فعالیت سیتوتوکسیک; Salvia lachnocalyx; Sesterterpenoid; Cytotoxic activity
Cytotoxic biflavones from Stellera chamaejasme
Keywords: فعالیت سیتوتوکسیک; Stellera chamaejasme; Chamaejasmenin E; Chamaejasmin D; ECD; Cytotoxic activity
New sesquiterpenoids from Aglaia odorata var. microphyllina and their cytotoxic activity
Keywords: فعالیت سیتوتوکسیک; Aglaia odorata var. microphyllina C. DC. Monogr; Sesquiterpenoids; Cytotoxic activity; Meliaceae
Complexes of platinum and palladium with β-diketones and DMSO: Synthesis, characterization, molecular modeling, and biological studies
Keywords: فعالیت سیتوتوکسیک; Metal complexes; Molecular modeling; β-Diketones; Mycobacterium tuberculosis; Cytotoxic activity
Toward synthesis of third-generation spin-labeled podophyllotoxin derivatives using isocyanide multicomponent reactions
Keywords: فعالیت سیتوتوکسیک; Podophyllotoxin; C-4 position; Spin labeled; Isocyanide multicomponent reactions; Cytotoxic activity
Flavonoid constituents, cytotoxic and antioxidant activities of Gleditsia triacanthos L. leaves
Keywords: فعالیت سیتوتوکسیک; Gleditsia triacanthos L.; Cytotoxic activity; Cancer cell lines; Flavone glycosides
Platinum(II) complexes with R2edda ligands (R = Me, Et, n-Pr; edda = ethylenediamine-N,N′-diacetate): Synthesis and characterization
Keywords: فعالیت سیتوتوکسیک; Platinum(II) complexes; Platinum(IV) complexes; R2edda-type ligands; Diastereoisomers; Crystal structure; Cytotoxic activity
Synthesis, structural characterization and cytotoxic activity of ternary copper(II)–dipeptide–phenanthroline complexes. A step towards the development of new copper compounds for the treatment of cancer
Keywords: فعالیت سیتوتوکسیک; Copper complexes; Dipeptide; Phen; DNA interaction; Cytotoxic activity
Phytochemical investigation of sesquiterpenes from the fruits of Schisandra chinensis and their cytotoxic activity
Keywords: فعالیت سیتوتوکسیک; Schisandra chinensis; Schisandraceae; Sesquiterpenes; Cytotoxic activity;
Cytotoxic activity of lignans from Justicia procumbens
Keywords: فعالیت سیتوتوکسیک; Justicia procumbens; Lignans; Cytotoxic activity; Structure-activity relationship;
Cytotoxic activity and DNA binding of naphthalimide derivatives with amino acid and dichloroacetamide functionalizations
Keywords: فعالیت سیتوتوکسیک; Naphthalimide; Dichloroacetamide; Cytotoxic activity; DNA binding
New cytotoxic compounds from flowers of Lawsonia inermis L.
Keywords: فعالیت سیتوتوکسیک; Lawsonia inermis L.; Cytotoxic activity;
Five new cyotoxic steroidal glycosides from the fruits of Solanum torvum
Keywords: فعالیت سیتوتوکسیک; Solanum torvum; Steroidal glycosides; Cytotoxic activity;
Volatile oil from striped African pepper (Xylopia parviflora, Annonaceae) possesses notable chemopreventive, anti-inflammatory and antimicrobial potential
Keywords: فعالیت سیتوتوکسیک; Xylopia parviflora; Essential oil; Cytotoxic activity; Anti-inflammatory; Antimicrobial;
Design, synthesis and cytotoxic activity of novel sulfonylurea derivatives of podophyllotoxin
Keywords: فعالیت سیتوتوکسیک; Podophyllotoxin; Sulfonylurea; Synthesis; Cytotoxic activity;
One strain-many compounds (OSMAC) method for production of polyketides, azaphilones, and an isochromanone using the endophytic fungus Dothideomycete sp.
Keywords: فعالیت سیتوتوکسیک; Dothideomycete sp.; Endophytic fungi; One strain-many compounds; OSMAC; Polyketide; Azaphilone; Isochromanone; Cytotoxic activity; Fungal metabolites;
Endosulfan decreases cytotoxic activity of nonspecific cytotoxic cells and expression of granzyme gene in Oreochromis niloticus
Keywords: فعالیت سیتوتوکسیک; Endosulfan; Nile tilapia; NCC; Cytotoxic activity; Granzyme;
Synthesis, antimicrobial and cytotoxic activity of novel azetidine-2-one derivatives of 1H-benzimidazole
Keywords: فعالیت سیتوتوکسیک; Antibacterial activity; Cytotoxic activity; Schiff bases; 2-Amino benzimidazole
Heteronuclear gold(I)–silver(I) sulfanylcarboxylates: Synthesis, structure and cytotoxic activity against cancer cell lines
Keywords: فعالیت سیتوتوکسیک; Gold(I) complexes; Silver(I) complexes; Heteronuclear complexes; Sulfanylpropenoic acids; Cytotoxic activity
Synthesis, characterization and ROS-mediated cytotoxic action of novel (S,S)-1,3-propanediamine-N,N′-di-2-(3-cyclohexyl)propanoic acid and corresponding esters
Keywords: فعالیت سیتوتوکسیک; Amine ligands; Apoptosis; n-Butyl ester; Cyclohexyl analogues; Cytotoxic activity; Oxidative stress
Synthesis and evaluation of 4-anilinoquinazoline bioisosteres as potential anti-breast cancer agents
Keywords: فعالیت سیتوتوکسیک; Breast cancer; Cytotoxic activity; Scaffold hopping; Synthesis; ThienopyrimidinesTKIs, tyrosine kinase inhibitors; HER2, human epidermal growth factor receptor 2; EGFR TK, epidermal growth factor receptor tyrosine kinase; EGFR PTK, epidermal growth factor
β-Ionone derived apoptosis inducing endoperoxides; Discovery of potent leads for anticancer agents
Keywords: فعالیت سیتوتوکسیک; Endoperoxides; Cytotoxic activity; Apoptosis; Anticancer activity;
Synthesis, spectroscopic, X-ray crystal structure, biological and DNA interaction studies of organotin(IV) complexes of 2-(4-ethoxybenzylidene) butanoic acid
Keywords: فعالیت سیتوتوکسیک; Distannoxane; Antimicrobial activity; Antitumor activity; Cytotoxic activity
Sesquiterpene lactones from Mikania micrantha and Mikaniacordifolia and their cytotoxic and anti-inflammatory evaluation
Keywords: فعالیت سیتوتوکسیک; Mikania micrantha; Mikania cordifolia; Sesquiterpene lactones; Cytotoxic activity; Anti-inflammatory activity;
Synthesis, structure, DNA binding, cleavage and biological activity of cobalt (III) complexes derived from triethylenetetramine and 1,10 phenanthroline ligands
Keywords: فعالیت سیتوتوکسیک; Triethylenetetramine; Crystal structure; DNA binding; Groove binding; Cytotoxic activity; Antimicrobial activity
Expression analysis and biological activity of moronecidin from rock bream, Oplegnathus fasciatus
Keywords: فعالیت سیتوتوکسیک; Rock bream; Moronecidin; Antimicrobial peptides; Antimicrobial activity; Cytotoxic activity;
Methyl angolensate and mexicanolide-type limonoids from the seeds of Cipadessa baccifera
Keywords: فعالیت سیتوتوکسیک; Cipadessa baccifera; Limonoids; Cytotoxic activity; Cancer cell lines;
Steroidal glycosides from the underground parts of Dracaena thalioides and their cytotoxic activity
Keywords: فعالیت سیتوتوکسیک; Dracaena thalioides; Agavaceae; Steroidal glycosides; Spirostanol glycosides; Cytotoxic activity; HL-60 cells; Apoptosis;
Synthesis, characterization and cytotoxic activity of novel Cu(II) and Co(II) complexes with 3-amino-5,5-dimethylhydantoin
Keywords: فعالیت سیتوتوکسیک; Copper and cobalt complexes; 5,5-Disubstituted hydantoins; Cytotoxic activity; Human tumor cell lines; Voltammetry
Synthesis, crystal studies, anti-tuberculosis and cytotoxic studies of 1-[(2E)-3-phenylprop-2-enoyl]-1H-benzimidazole derivatives
Keywords: فعالیت سیتوتوکسیک; 1H-benzimidazoles; Anti-tuberculosis; Cytotoxic activity; Crystal structure
4,4â²-Diaminodiphenyl ether derivatives: Synthesis, spectral, optical, thermal characterization and in-vitro cytotoxicity against Hep 3B and IMR 32 human cell lines
Keywords: فعالیت سیتوتوکسیک; 4,4â²-Diaminodiphenyl ether derivatives; Cytotoxic activity; MTT assay; Optical properties;
Synthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines
Keywords: فعالیت سیتوتوکسیک; Naphthoquinone; 1,2,3-Triazole; Organic synthesis; Cytotoxic activity; Leukemia; Cancer
The cytotoxic activity of Vitex agnus castus L. essential oils and their biochemical mechanisms
Keywords: فعالیت سیتوتوکسیک; Vitex agnus castus; Chasteberry; Cytotoxic activity; Essential oil; Apoptosis;
Synthesis, spectral characterization and biological evaluation of Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes with thiosemicarbazone ending by pyrazole and pyridyl rings
Keywords: فعالیت سیتوتوکسیک; Thiosemicarbazone complexes; ABTS antioxidant; Cytotoxic activity
Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity
Keywords: فعالیت سیتوتوکسیک; (R)- and (S)-Sulforaphane and homologues; Enantiodivergent synthesis; Activation of Nrf2 factor; Cytotoxic activity; DAG-methodology;
Formulation and In Vitro Characterization of Thermosensitive Liposomes for the Delivery of Irinotecan
Keywords: فعالیت سیتوتوکسیک; Liposomes; Irinotecan; drug delivery; responsive delivery systems; controlled release; Caco-2 cells; drug uptake; cytotoxic activity;
Synthesis, crystal structures, in vitro DNA binding, antibacterial and cytotoxic activities of new di- and polynuclear silver(I) saccharinate complexes with tertiary monophosphanes
Keywords: فعالیت سیتوتوکسیک; Silver(I); Saccharinate; Phosphine; DNA binding; Antibacterial activity; Cytotoxic activity
Synthesis and characterization of a series of gold(III) complexes with the 4,4′-dimethyl-2,2′-bipyridine ligand: Counterion influence on the cytotoxicity of gold(III) complexes
Keywords: فعالیت سیتوتوکسیک; Gold(III) complexes; 4,4′-Dimethyl-2,2′-bipyridine; Crystal structure; Cytotoxic activity; Cyclic voltammetry
Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties
Keywords: فعالیت سیتوتوکسیک; Pyrrolopyrimidines; Sulfonamide; Cytotoxic activity; Carbonic anhydrase inhibitors; Molecular docking
Semisynthesis and in vitro cytotoxic evaluation of new analogues of 1-O-acetylbritannilactone, a sesquiterpene from Inula britannica
Keywords: فعالیت سیتوتوکسیک; 1-O-Acetylbritannilactone sesquiterpene; Cytotoxic activity; Structure–activity relationship
Synthesis, characterization, antibacterial and antitumoral activities of mononuclear zinc complexes containing tridentate amine based ligands with N3 or N2O donor groups
Keywords: فعالیت سیتوتوکسیک; Mononuclear Zn complexes; ESI(+)-MS/MS; Crystal structure; Antibacterial activity; Cytotoxic activity; Transmission electron microscopy (TEM)
Triterpene glycosides and other polar constituents of shea (Vitellaria paradoxa) kernels and their bioactivities
Keywords: فعالیت سیتوتوکسیک; Shea butter; Vitellaria paradoxa; Sapotaceae; Shea kernel; Oleanane-type triterpene glycoside; Antioxidant activity; Anti-inflammatory activity; Melanogenesis-inhibitory activity; Epstein-Barr virus early antigen (EBV-EA); Cytotoxic activity;
Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho
Keywords: فعالیت سیتوتوکسیک; Asa-cyclotetraphosphazenes; Chirality; Crystal structure; Cytotoxic activity; Antituberculosis activity; Biological activity;