Keywords: DA، dopaminergic; DA, dopaminergic; DBS, deep brain stimulation; GPe, external globus pallidus; GPi, internal globus pallidus; PD, Parkinson’s disease; PPN, pedunculopontine; SNc, substantia nigra pars compacta; SNr, substantia nigra pars reticulata; STN, subthalamic nucle
مقالات ISI DA، dopaminergic (ترجمه نشده)
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Keywords: DA، dopaminergic; α-Syn, alpha-synuclein; Aβ, amyloid-beta protein; BBB, blood–brain barrier; CNS, central nervous system; CSF, cerebrospinal fluid; DA, dopaminergic; ICV, intracerebroventricular; LBs, Lewy bodies; LPS, lipopolysaccharide; LRP-1, low-density lipoprotein re
Keywords: DA، dopaminergic; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; DA, dopaminergic; ER, endoplasmic reticulum; 4E-BP1, eukaryotic initiation factor 4E (eIF4E)-binding protein; HD, Huntington's disease; LRRK2, leucine-rich repeat kinase 2; MPTP, 1-methyl-4-phen
Keywords: DA، dopaminergic; 5-LOX, 5-lipoxygenase; CNS, central nervous system; COX, cyclooxygenase; CysLT1R, cysteinyl leukotriene receptor 1; CysLTs, cysteinyl leukotrienes; DA, dopaminergic; DAPI, 4′, 6-diamidino-2-phenylindole; DMEM, Dulbecco׳s modified Eagle׳s medium; ELISA, en
Role of pedunculopontine cholinergic neurons in the vulnerability of nigral dopaminergic neurons in Parkinson's disease
Keywords: DA، dopaminergic; ChAT, choline acetyl transferase; DA, dopaminergic; Dtx-UII, diphtheria toxin coupled to urotensin II; Iba-1, ionized calcium-binding adaptor molecule 1; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NADPH, nicotinamide adenine dinucleotide phosphat
A simple method for differentiation of H9 cells into neuroectoderm
Keywords: DA، dopaminergic; ESC, embryonic stem cell; NE, neuroectoderm; RT-PCR, reverse transcription with polymerase chain reaction; IF, immunofluorescence; IB, immunoblotting; TH, tyrosine hydroxylase; DA, dopaminergic; PD, Parkinson's disease; LCD, localized cell density; AA, as
Coordinated interaction of Down syndrome cell adhesion molecule and deleted in colorectal cancer with dynamic TUBB3 mediates Netrin-1-induced axon branching
Keywords: DA، dopaminergic; APC, adenomatous polyposis coli protein; BSA, bovine serum albumin; CDK5, cyclin-dependent kinase 5; DA, dopaminergic; DCC, deleted in colorectal cancer; DCX, doublecortin; DMEM, Dulbecco’s modified Eagle’s medium; DSCAM, Down syndrome cell adhesion molec
Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption
Keywords: DA، dopaminergic; DJ-1; Thioredoxin; Thioredoxin reductase; Oxidative stress; Mitochondria; Parkinson’s diseasePD, Parkinson’s disease; DA, dopaminergic; Trx, thioredoxin; TrxR, thioredoxin reductase; Trx1, cytosolic trx; Trx2, mitochondrial trx; TrxR1, cytosolic TrxR; Trx
Immunohistochemical demonstration of urocortin 1 in Edinger–Westphal nucleus of the human neonate: Colocalization with tyrosine hydroxylase under acute perinatal hypoxia
Keywords: DA، dopaminergic; ChAT, choline acetyltransferase; CRF, corticotropin-releasing factor; DA, dopaminergic; DAB, 3,3′-diaminobenzidine tetrahydrochloride; EW, Edinger–Westphal nucleus; EWcp, EW centrally projecting population; EWpg, EW preganglionic population; GBB, Greek Br
Sertraline and rapid eye movement sleep without atonia: An 8-week, open-label study of depressed patients
Keywords: DA، dopaminergic; 5-HT, serotonin; AASM-2007, American Academy of Sleep Medicine 2007 version; AHI, apnea–hypopnea index; AI, arousal index; ANOVA, one-way analysis of variance; BMI, body mass index; CT, computed tomography; DA, dopaminergic; DSM-IV, Diagnostic and Statist
BMP-Smad 1/5/8 signalling in the development of the nervous system
Keywords: DA، dopaminergic; ALK, Activin Receptor-like Kinases; BMP(s), Bone Morphogenetic Protein(s); BMPR, BMP receptor(s); CNS, Central Nervous System; Co-Smads, Common-mediator Smads; DA, Dopaminergic; DG, Dentate Gyrus; dI, Dorsal Interneuron; DRG, Dorsal Root Ganglion; E, Embr
Transient receptor potential vanilloid subtype 1 contributes to mesencephalic dopaminergic neuronal survival by inhibiting microglia-originated oxidative stress
Keywords: DA، dopaminergic; TRPV1, transient receptor potential vanilloid subtype 1; CAP, capsaicin; CZP, capsazepine; MFB, median forebrain bundle; SN, substantia nigra; DA, dopaminergic; ROS, reactive oxygen speciesParkinson's disease; 1-Methyl-4-phenylpyridinium (MPP+); Capsaicin
A new alternative NF-ΚB Pathway mediated the neuroprotection of GDNF on 6-OHDA-induced DA neurons neurotoxicity
Keywords: DA، dopaminergic; GDNF, glial cell line-derived neurotrophic factor; DA, dopaminergic; SNc, substantia nigra pars compacta; NIK, NF-κB-inducing kinase; I B, inhibitor of B; IKK, I B kinase; TH, tyrosine hydroxylaseGDNF; DA neurons; NIK; IKKα; NF-κB
Involvement of microglial RhoA/Rho-Kinase pathway activation in the dopaminergic neuron death. Role of angiotensin via angiotensin type 1 receptors
Keywords: DA، dopaminergic; ACE, Angiotensin converting enzyme; AII, angiotensin II; ARBs, AT1 receptor blockers; AT1, Type 1 receptors; cDNA, Complementary DNA; Ct, Cycle threshold; DA, Dopaminergic; DIV, Days in vitro; dNTP, Deoxynucleotide triphosphate; GSI-B4, Isolectin B4; ir,
Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: Implications for early intervention on disease progression
Keywords: DA، dopaminergic; MAO-B, monoamine oxidase B; dox, doxycycline; PD, Parkinson's disease; SN, substantia nigra; CI, mitochondrial complex I; TH, tyrosine hydroxylase; ST, striatum; ROS, reactive oxygen species; DR, dox removal; DA, dopaminergic; NDA, non dopaminergicMonoami
Calbindin-D28K inhibits apoptosis in dopaminergic neurons by activation of the PI3-kinase-Akt signaling pathway
Keywords: DA، dopaminergic; calbindin-D28K; Parkinson's disease; dopaminergic neuron; PI-3K/Akt signaling pathwayCaBP, calbindin-D28k; DA, dopaminergic; DMEM/F12, Dulbecco’s modified eagle’s medium/ham’s nutrient mixture F12; FITC, fluorescein isothiocyanate; GDNF, glial cell line-d
Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y
Keywords: DA، dopaminergic; Parkinson's disease; autophagy enhancer; rotenone; SH-SY5Y cells; valproic acid; carbamazepineCBZ, carbamazepine; Chl, chloroquine; DA, dopaminergic; DMSO, dimethyl sulfoxide; LC3, microtubule-associated protein1 light chain 3; LiCl, lithium; MMP, mitocho
Embryonic stem cells in non-human primates: An overview of neural differentiation potential
Keywords: DA، dopaminergic; Embryonic stem cells ESC; Non-human Primate; Self-renewal; Neural differentiation; Neural stem cellsBMP, bone morphogenetic protein; DA, dopaminergic; EB, embryoid body; EC, embryonal carcinoma; ES, embryonic stem; EGF, epidermal growth factor; FBS, foeta
Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: Implications for early intervention on disease progression
Keywords: DA، dopaminergic; MAO-B, monoamine oxidase B; dox, doxycycline; PD, Parkinson's disease; SN, substantia nigra; CI, mitochondrial complex I; TH, tyrosine hydroxylase; ST, striatum; ROS, reactive oxygen species; DR, dox removal; DA, dopaminergic; NDA, non dopaminergicMonoami
dGIPC is required for the locomotive activity and longevity in Drosophila
Keywords: DA، dopaminergic; DA, dopaminergic; GAIP, Gα interacting protein; TH, tyrosine hydroxylase; GIPC, GAIP interacting protein, C terminus; GPCR, G-protein coupled receptorP element mutagenesis; Central nervous system; Lifespan; Glia; PDZ domain; Drosophila
Glial cell line-derived neurotrophic factor gene therapy ameliorates chronic hyperprolactinemia in senile rats
Keywords: DA، dopaminergic; aging; DA neurodegeneration; TIDA neurons; chronic hyperprolactinemia; GDNF; gene therapyAAV, adeno-associated viral; ARC, arcuate nucleus; AVP, arginine–vasopressin; DA, dopaminergic; EBM, Eagle's Basal Medium; GDNF, glial cell line-derived neurotrophic
Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1β mutants
Keywords: DA، dopaminergic; PD, Parkinson's disease; ROS, reactive oxygen species; DA, dopaminergic; BHT, butilated hydroxytoluene; DCFH-DA, 2,7-dichlorofluorescein diacetate; DMSO, dimethylsulfoxide; TCA, trichloroacetic acid; MDA, malodialdehyde; PMSF, pheylmethylsulfonyl fluoride
Protective effects of xyloketal B against MPP+-induced neurotoxicity in Caenorhabditiselegans and PC12 cells
Keywords: DA، dopaminergic; PD, Parkinson's disease; MPP+, 1-methyl-4-phenylpyridinium ion; PC12 cells, Rat pheochromocytoma; DA, dopaminergic; ROS, Reactive oxygen species; GSH, Glutathione; DCF-DA, Dichlorofluorescein diacetate; SN, Substantia nigraXyloketal B; MPP+; Mitochondria;
Aggressive behavior during social interaction in mice is controlled by the modulation of tyrosine hydroxylase expression in the prefrontal cortex
Keywords: DA، dopaminergic; noradrenaline; tyrosine hydroxylase; locus coeruleus; prefrontal cortex; aggression; social behaviorsABC, avidin-biotine-peroxydase complex; Cg1, cingular; DA, dopaminergic; DSP-4, N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrocloride; LC, locus coeru
Proteomic analysis of expression and protein interactions in a 6-hydroxydopamine-induced rat brain lesion model
Keywords: DA، dopaminergic; 2-DE, two-dimensional gel electrophoresis; 6-OHDA, 6-hydroxydopamine; DA, dopaminergic; GFAP, glial fibrillary acidic protein; NDUFS3 subunit, NADH-ubiquinone oxidoreductase 30 kDa subunit; PD, Parkinson's disease; SD rat, Sprague–Dawley rat; SN, substant
The ependymal route for insulin-like growth factor-1 gene therapy in the brain
Keywords: DA، dopaminergic; ependymal cells; gene delivery; TK/GFPfus; IGF-1; adenoviral vectors; mCMV promoterCSF, cerebrospinal fluid; DA, dopaminergic; DAPI, 4′,6-diamidino-2-phenylindole; EAE, experimental autoimmune encephalomyelitis; GFP, green fluorescent protein; IF, immunof
Modulation of connexin 43 in rotenone-induced model of Parkinson's disease
Keywords: DA، dopaminergic; gap junction; connexin 43; astrocyte; Parkinson's disease; dopaminergic; basal gangliaCx43, connexin43; DA, dopaminergic; DMSO, dimethyl sulfoxide; FRAP, fluorescence recovery after photobleaching; GJIC, gap junctional intercellular communication; PBST, P
Blockade of the translocation and activation of c-Jun N-terminal kinase 3 (JNK3) attenuates dopaminergic neuronal damage in mouse model of Parkinson's disease
Keywords: DA، dopaminergic; PD, Parkinson's disease; DA, dopaminergic; SNc, substantia nigra pars compacta; NMDA, N-methyl-d-aspartate; DNQX, 6,7-dinitroquinoxaline-2,3(1H,4H)-dione; MAPK, mitogen-activated protein kinase; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; JNK, c-J
Effects of GDNF pretreatment on function and survival of transplanted fetal ventral mesencephalic cells in the 6-OHDA rat model of Parkinson's disease
Keywords: DA، dopaminergic; 6-OHDA, 6-hydroxy-dopamine; ANOVA, analysis of variance; BDNF, brain-derived neurotrophic factor; CNS, central nervous system; DA, dopaminergic; DIV, days in vitro; E, embryonic day; FFRT, free-floating roller tubes; GDNF, glial cell line-derived neurotro
A new road to neuroinflammation in Parkinson's disease?
Keywords: DA، dopaminergic; CyR, cytokine receptor; DA, dopaminergic; ECD, ectodomain; Ig, immunoglobulin; GABA, gamma-aminobutyric acid; G-protein, guanine nucleotide-binding protein; GPCR, G-protein coupled receptor; JAK, Janus kinase; LRR, leucine-rich repeat; MCP, monocyte chemo
Catalpol protects mesencephalic neurons against MPTP induced neurotoxicity via attenuation of mitochondrial dysfunction and MAO-B activity
Keywords: DA، dopaminergic; CNS, central nervous system; DA, dopaminergic; DCFH, 2′,7′-dichlorofluorescein; DCFH-DA, 2′,7′-dichlorofluorosecin diacetate; DMEM/F12, Dulbecco’s modified Eagle’s medium/nutrient F12; DMSO, dimethyl sulfoxide; ETC, electron transport chain; FBS, fetal bo
Individual dopamine midbrain neurons: Functional diversity and flexibility in health and disease
Keywords: DA، dopaminergic; Cav1.3, voltage-gated calcium channel; DA, dopaminergic; D2R, dopamine receptor subtype 2; GIRK2, G-protein-coupled inwardly rectifying potassium channel; HCN, hyperpolarization and cyclic nucleotide gate cation channel; ISI, interspike interval; K-ATP, A
The β-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons
Keywords: DA، dopaminergic; CCL2, β-chemokine ligand 2; CCL7, β-chemokine ligand 7; DA, Dopaminergic; TH, thyrosine hydroxylase; BrdU, bromodioxyuridine; VM, ventral mesencephalon; Nurr1, nurr77-related receptor; PD, Parkinson's diseaseChemokines; CNS; Midbrain; Dopamine; Stem cells
Dopaminergic mesencephalic systems and behavioral performance in very old rats
Keywords: DA، dopaminergic; aging; mesencephalic; tyrosine hydroxylase; morphometry; motor tests; open fieldANOVA, analysis of variance; DA, dopaminergic; DAB, 3,3-diaminobenzidine tetrahydrochloride; IA, interaural; ml, medial lemniscus; mp, mammillary peduncle; SN, substantia nigr
A nitric oxide synthase inhibitor decreases 6-hydroxydopamine effects on tyrosine hydroxylase and neuronal nitric oxide synthase in the rat nigrostriatal pathway
Keywords: DA، dopaminergic; 6-OHDA, 6-hydroxydopamine; l-NOARG, NG-nitro-l-arginine; DA, dopaminergic; NOS, nitric oxide synthase; nNOS, neuronal nitric oxide synthase; TH, tyrosine-hydroxylase; PD, Parkinson's disease; TH+, tyrosine-hydroxylase positive; nNOS+, neuronal nitric oxid
Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: Persisting effects on locomotor activity, learning and nicotine self-administration
Keywords: DA، dopaminergic; 6-OHDA; radial-arm maze; dopamine; 5-HT; nucleus accumbens; striatumACSF, artificial cerebrospinal fluid; DA, dopaminergic; VTA, ventral tegmental area; 6-OHDA, 6-hydroxydopamine
Progress in Parkinson's disease—Where do we stand?
Keywords: DA، dopaminergic; AAV2, adeno-associated type 2 virus; ALS, amyotrophic lateral sclerosis; CNS, central nervous system; COMT, catecholamine-O-methyl transferase; CoQ10, Co-enzyme Q10; DA, dopaminergic; DATATOP, deprenyl and tocopherol antioxidative therapy for Parkinson's
Modulation of parkin gene expression in noradrenergic neuronal cells
Keywords: DA، dopaminergic; AR-JP, autosomal recessive juvenile Parkisonism; DA, dopaminergic; LC, locus coeruleus; NA, noradrenergic; PD, Parkinson's disease; SN, substantia nigra; TCA, trichloroacetic acid; UCH-L1, ubiquitin carboxyl-terminal hydrolaseParkin; DBH; Differentiation;
Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits
Keywords: DA، dopaminergic; PD, Parkinson's disease; DA, dopaminergic; pI, isoelectric point; SNc, susbtantia nigra pars compacta; DM; dorsomedial; JNK, Jun N-terminal Kinase.Parkinson's disease; Paraquat; Neurodegeneration; Climbing ability
A choice behavior for morphine reveals experience-dependent drug preference and underlying neural substrates in developing larval zebrafish
Keywords: DA، dopaminergic; choice behavior; zebrafish; reward; addiction; opioid system; dopamine systemANOVA, analysis of variance; CPP, conditioned place preference; DA, dopaminergic; LC/MS/MS, high performance liquid chromatography–tandem mass spectrometry; MOR, μ-opioid recepto
The physiological and pharmacological role of basic fibroblast growth factor in the dopaminergic nigrostriatal system
Keywords: DA، dopaminergic; DA, dopaminergic; FGF-2, basic fibroblast growth factor; FGFR, FGF receptor; PD, Parkinson's disease; SN, substantia nigra; SNpc, SN pars compactaMidbrain; Neurotoxin-induced lesion; Substantia nigra; Parkinson's disease; Grafting; Rat; Mutant mice; FGF r
The role of Ret receptor tyrosine kinase in dopaminergic neuron development
Keywords: DA، dopaminergic; Ret receptor tyrosine kinase; glial cell line–derived neurotrophic factor; dopamine transporter; antisense oligonucleotides; apoptosisAS-ODN, antisense oligonucleotides; DA, dopaminergic; DAB, 3,3′-diaminobenzidine; DAT, dopamine transporter; E11.5, embry
A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice
Keywords: DA، dopaminergic; ALS, amyotrophic lateral sclerosis; GDNF, glial cell line-derived neurotrophic factor; TTC, tetanus toxin fragment C; DA, dopaminergic; TH, tyrosine hydroxylaseProtein delivery; Glial cell line-derived neurotrophic factor; Tetanus toxin fragment C; Motor
Nociceptive responses of midbrain dopaminergic neurones are modulated by the superior colliculus in the rat
Keywords: DA، dopaminergic; electrophysiology; dopamine; pain; nociception; sensory regulationANOVA, analysis of variance; BSA, bovine serum albumin; CED, Cambridge Electronic Design; DA, dopaminergic; DAB, diaminobenzidine; FLI, Fos-like immunoreactivity; NGS, normal goat serum; NH
Developmental origin and fate of meso-diencephalic dopamine neurons
Keywords: DA، dopaminergic; 6-OHDA, 6-hydroxydopamine; A/P, anterior–posterior; D/V, dorsoventral; DA, dopaminergic; ES-cell, embryonic stem cell; l-DOPA, 3,4-dihydroxyphenylalanine; mDA, mesencepalic dopaminegic; mdDA, meso-diencephalic dopaminergic; MPTP, 1-methyl-4-phenyl-1,2,3,6