DHEA prevents ribavirin-induced anemia via inhibition of glucose-6-phosphate dehydrogenase
Keywords: DHEA; Ribavirin; Anemia; Hemolysis; Glycolysis;
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Maintaining physiological testosterone levels by adding dehydroepiandrosterone to combined oral contraceptives: I. Endocrine effects
Keywords: Oral contraception; Free testosterone; SHBG; DHEA; Androgens;
Obesity is positively associated with arachidonic acid-derived 5- and 11-hydroxyeicosatetraenoic acid (HETE)
Keywords: AEA; arachidonoyl ethanolamide; AG; arachidonoyl glycerol; ALA; alpha-linolenic acid; ARA; arachidonic acid; BHT; butylated hydroxytoluene; BMI; body mass index; COX; cyclooxygenase; CYP; cytochrome P450 enzymes; DGLA; dihomo-gamma-linolenic acid; DHA; do
Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue
Keywords: ConA; Concanavalin A; OA-5-HT; oleoyl serotonin; SA-5-HT; stearoyl serotonin; PA-5-HT; palmitoyl serotonin; AA-5-HT; arachidonoyl serotonin; AEA; arachidonoyl ethanolamide (anandamide); DHA; docosahexaenoic acid; DHA-5-HT; docosahexaenoyl serotonin; DHEA;
N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation
Keywords: ABHD4; α/β-hydrolase domain 4; AEA; N-arachidonoylethanolamine; DHEA; N-docosahexaenoylethanolamine; DTEA; N-docosatetraenoylethanolamine; FAAH; fatty acid amide hydrolase; GDE1; glycerophosphodiester phosphodiesterase 1; NAAA; N-acylethanolamine-hydrol
Efficacy of Dehydroepiandrosterone (DHEA) to overcome the effect of ovarian ageing (DITTO): A proof of principle double blinded randomized placebo controlled trial
Keywords: Infertility; DHEA; In-vitro fertilisation; Low ovarian reserve; Poor responders; randomised controlled trial;
Î4-3-ketosteroids as a new class of substrates for the cytosolic sulfotransferases
Keywords: SULT; Cytosolic sulfotransferase; PAPS; 3â²-phosphoadenosine 5â²-phosphosulfate; DHEA; dehydroepiandrosterone; KSI; Ketosteroid isomerase; Sulfotransferase; Ketosteroid; 4-androstene-3,17-dione; Ketosteroid isomerase;
Cortisol and DHEA in development and psychopathology
Keywords: 11β-HSD1; 11β-hydroxysteroid dehydrogenase type 1; 11β-HSD2; 11β-hydroxysteroid dehydrogenase type 2; 3βHSD; 3β-hydroxysteroid dehydrogenase; ACTH; Adrenocorticotropic hormone; ADHD; Attention deficit hyperactivity disorder; AVP; Arginine vasopressi
Oleic acid-derived oleoylethanolamide: A nutritional science perspective
Keywords: ABHD4; α/β-hydrolase domain-containing protein 4; AEA; arachidonoylethanolamide; A:G; android-to-gynoid; CHO; carbohydrate; DHEA; docosahexaenoylethanolamide; DXA; dual-energy X-ray absorptiometry; E; energy; EEA; elaidoylethanolamide; FAAH; fatty acid
BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the “weaver” mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor
Keywords: Parkinson's-disease; Microneurotrophin; Neuroprotection; TrkB-receptor-signaling; NGL (NF-κB; GFP.Luc)-mice; Arg1; Arginase; BBB; blood-brain-barrier; BDNF; Brain-Derived Neutrotrophic Factor; BNN-20; 17-beta-spiro-[5-androsten-17,2'-oxiran]-3beta-ol; CS
Human dehydrogenase/reductase (SDR family) member 11 is a novel type of 17β-hydroxysteroid dehydrogenase
Keywords: DHRS11; 17β-Hydroxysteroid dehydrogenase; 3β-Hydroxysteroid dehydrogenase; Dehydroepiandrosterone; Neurosteroid; Isolithocholic acid; SDR; short-chain dehydrogenase/reductase; DHRS11; dehydrogenase/reductase (SDR family) member 11; spDHRS11; spliced iso
A validated LC-MS/MS method for the sensitive quantitation of serum 7alpha hydroxy-, 7beta hydroxy- and 7keto-dehydroepiandrosterone using a novel derivatization reagent
Keywords: DHEA; 7α OH-DHEA; 7β OH-DHEA; 7 oxo-DHEA; LC-MS/MS;
Exploratory study of the association of steroid profiles in stimulated ovarian follicular fluid with outcomes of IVF treatment
Keywords: IVF; in vitro fertilization; sFF; stimulated follicular fluid; IAs; immunoassays; Pr; pregnenolone; 17OHPr; 17 hydroxy pregnenolone; A4; androstenedione; Te; testosterone; DHEA; dehydroepiandrosterone; E1; estrone; E2; estradiol; E3; estriol; P4; progeste
Associations of bisphenol A and polychlorinated biphenyls with spermatogenesis and steroidogenesis in two biological fluids from men attending an infertility clinic
Keywords: DHEA; dehydroepiandrosterone; T; testosterone; ADIONE; androstenedione; PREG; pregnenolone; 17-OH-PREG; 17-hydroxy-pregnenolone; DHT; dihydrotestosterone; E1; estrone; E2; estradiol; E3; estriol; LH; luteinizing hormone; FSH; follicle stimulating hormone;
Estrone sulfate and dehydroepiandrosterone sulfate: Transactivation of the estrogen and androgen receptor
Keywords: AR; androgen receptor; DC; dextran/charcoal; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone sulfate; DHT; dihydrotestosterone; E1; estrone; E1S; estrone sulfate; E2; 17β-estradiol; ER; estrogen receptor; FCS; fetal calf serum; HF; hydroxyflu
The feto-placental unit, and potential roles of dehydroepiandrosterone (DHEA) in prenatal and postnatal brain development: A re-examination using the spiny mouse
Keywords: 3β-HSD; 3β-hydroxysteroid dehydrogenase; 17-OH-PREG; 17-hydroxypregnenolone; ACTH; adrenocorticotrophic hormone; CNS; central nervous system; CRH; corticotropin releasing hormone; DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosteronesulphate; GAB
Exposure to acute stress enhances decision-making competence: Evidence for the role of DHEA
Keywords: Stress; Decision-making competence; DHEA; Cortisol; Decision-making; Acute stress;
Chemical derivatization for enhancing sensitivity during LC/ESI-MS/MS quantification of steroids in biological samples: a review
Keywords: 1,25(OH)2D2; 1α,25-dihydroxyvitamin D2; 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 17(OH)P4; 17α-hydroxyprogesterone; 17(OH)P5; 17α-hydroxypregnenolone; 24,25(OH)2D3; 24R,25-dihydroxyvitamin D3; 25(OH)D2; 25-hydroxyvitamin D2; 25(OH)D3; 25-hydroxyvitamin
An improved micro-method for the measurement of steroid profiles by APPI-LC-MS/MS and its use in assessing diurnal effects on steroid concentrations and optimizing the diagnosis and treatment of adrenal insufficiency and CAH
Keywords: DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; 17 OHP; 17α-hydroxyprogesterone; 21-OHD; 21-hydroxylase deficiency; CAH; ongenital adrenal hyperplasia; HSD; 3α-hydroxysteroid dehydrogenase; LC-MS/MS; liquid chromatography-tandem mass spectro
MicroRNAs related to androgen metabolism and polycystic ovary syndrome
Keywords: Polycystic ovary syndrome; MicroRNA; Androgens; DHEA; DHEAS; Ovarian steroid metabolism; Biomarker; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone sulfate; PCOS; polycystic ovary syndrome; T2D; type 2 diabetes mellitus; CYP; Cytochrome P450;
Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis
Keywords: CYP17A1; Cytochrome b5; Redox donor; Androgen synthesis; Nanodiscs; Cyt b5; cytochrome b5; Mn-b5; manganese protoporphyrin IX substituted cyt b5; DHEA; dehydroepiandrosterone; PREG; pregnenolone; OH-PREG; 17α-hydroxypregenolone;
Oxylipins, endocannabinoids, and related compounds in human milk: Levels and effects of storage conditions
Keywords: DHET; dihydroxy-eicosatrienoic acid; HETE; hydroxy-eicosatetraenoic acid; LTB4; leukotriene B4; EpOME; epoxy-octadecenoic acid; EET; epoxy-eicosatrienoic acid; TXB2; thromboxane B2; PGD2; prostaglandin D2; HODE; hydroxy-octadecadienoic acid; DiHOME; dihyd
Regulators of mitochondrial complex I activity: A review of literature and evaluation in postmortem prefrontal cortex from patients with bipolar disorder
Keywords: BD; bipolar disorder; DHEA; Dehydropiandrosterone; DJ-1; protein deglycase; DOPAC 3,4; dihydroxyphenylacetic acid; FMN; flavine mononucleotide; Grx2; glutaredoxin 2; GSH; glutathione; 6-OHDA; 6-hydroxydopamine; IMP-2; insulin-like growth factor 2 [IGF2] m
Electrical muscle stimulation elevates intramuscular BDNF and GDNF mRNA following peripheral nerve injury and repair in rats
Keywords: BDNF; brain-derived neurotrophic factor; CNTF; ciliary neurotrophic factor; DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; EMS; electrical muscle stimulation; GDNF; glial cell line-derived neurotrophic factor; iCNAP; integrated compound nerve act
Pro-sexual and androgen enhancing effects of Tribulus terrestris L.: Fact or Fiction
Keywords: TT; Tribulus terrestris L.; DHEA; Dehydroepiandrosterone; DHEA-S; Dehydroepiandrosterone-sulfate; LH; Luteinizing hormone; TS; Testosterone; DT; Dihydrotestosterone; FSH; follicle stimulating hormone; ED; Estradiol; PR; Progesterone; ES; Estrogen; PL; Pro
Docosahexaenoyl serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23-IL-17 signaling in macrophages
Keywords: AA-5-HT; arachidonoyl serotonin; AEA; arachidonoyl ethanolamide (anandamide); COX-2; cyclooxygenase 2; DHA; docosahexaenoic acid (22:6n-3); DHA-5-HT; docosahexaenoyl serotonin; DHEA; docosahexaenoyl ethanolamine; EPA-5-HT; eicosapentaenoyl serotonin; FAA;
Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line
Keywords: Androst-4-en-3-one derivatives; LNCaP cells; PC3 cells; Rat peripheral blood mononuclear cells (PBMC); Prostate cancer; Sulforhodamine B assay; 5αR; 5α-reductase enzyme; AR; androgen receptor; BPH; benign prostatic hyperplasia; DHEA; dehydroepiandroster
Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation
Keywords: Neurotrophins; Nerve growth factor (NGF); TrkA; Neurodegeneration; Neurotrophin receptors signaling; Neuronal apoptosis; Steroid; STD NMR; Molecular modeling; NGF; nerve growth factor; BDNF; brain-derived neurotrophic factor; NT-3; neurotrophin-3; CYP17;
Determination of steroid hormones in human plasma by GC-triple quadrupole MS
Keywords: DHEA; Pregnenolone; Testosterone; Dihydrotestosterone; Steroid hormones;
Dehydroepiandrosterone-enhanced dual specificity protein phosphatase (DDSP) prevents diet-induced and genetic obesity
Keywords: Dehydroepiandrosterone; DHEA-enhanced dual specificity protein phosphatase; Obesity; p38 MAPK; Leptin; DHEA; dehydroepiandrosterone; DDSP; DHEA-enhanced dual specificity protein phosphatase; MAPK; mitogen-activated protein kinase; WAT; white adipose tissu
New Techniques for Augmenting Saliva Collection: Bacon Rules and Lozenge Drools
Keywords: saliva; bacon; cortisol; testosterone; DHEA; interference;
Mechanisms of drug resistance that target the androgen axis in castration resistant prostate cancer (CRPC)
Keywords: ADMET; absorption distribution, metabolism, elimination and toxicity; Î4-A; 4-androstene-3,17-dione; Î5-Adiol; 5-androstene-3β,17β-diol; 3α-Adiol; 5α-androstane-3α,17β-diol; Adione; 5α-androstane-3,17-dione; ADT; androgen deprivation therapy; AR;
Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor
Keywords: 5αRed1; 5α-reductase type 1; 3β-HSD(1); 3β-hydroxysteroid dehydrogenase (type 1); 17β-HSD(3); 17β- hydroxysteroid dehydrogenase (type 3); cAMP; 8-bromoadenosine 3â²,5â²-cyclic monophosphate; AR; androgen receptor; BPA; bisphenol A; BPF; bisphenol
Dehydroepiandrosterone prevents linoleic acid-induced endothelial cell senescence by increasing autophagy
Keywords: ANOVA; one-way analysis of variance; AMPK; AMP-activated protein kinase; ATG; autophagy related genes; CVD; cardiovascular disease; DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosterone sulfate; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric ox
Detection, identification and quantification by 1H NMR of adulterants in 150 herbal dietary supplements marketed for improving sexual performance
Keywords: AminTad; aminotadalafil; DepipTSild; depiperazinothiosildenafil; DHEA; dehydroepiandrosterone; dMcarbo; desmethylcarbodenafil; DOSY NMR; diffusion-ordered spectroscopy NMR; DS; dietary supplements; dTdMcarbo; dithiodesmethylcarbodenafil; MSild; methisosil
Active site proton delivery and the lyase activity of human CYP17A1
Keywords: PREG; pregnenolone; OH-PREG; 17α-hydroxy-pregnenolone; PROG; progesterone; OH-PROG; 17α-hydroxy-progesterone; DHEA; dehydroepiandrosterone; AD; androstenedione; cyt-b5; cytochrome b5; Cpd I; Compound I; CYP17A1; T306A; Proton delivery; Compound I; Nucel
Age- and gender-associated changes in the concentrations of serum TGF-1β, DHEA-S and IGF-1 in healthy captive baboons (Papio hamadryas anubis)
Keywords: TGF-1β; transforming growth factor-1β; DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosterone sulfate; IGF-1; insulin like growth factor-1; IGFBP-3; insulin like growth factor binding protein-3; IL; interleukin; Ig; immunoglobulin; Non-human prima
Next-generation steroidogenesis inhibitors, dutasteride and abiraterone, attenuate but still do not eliminate androgen biosynthesis in 22RV1 cells in vitro
Keywords: DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; LHRH; luteinizing hormone releasing hormone; LH; luteinizing hormone; AR; androgen receptor; CRPC; castration resistant prostate cancer; PSA; prostate specific antigen; SRD5A1/2; 5-alpha-reductase is
A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders
Keywords: DHEA; in vitro fertilization; ovarian response markers; poor responders;
Characterization and engineering of 3-ketosteroid-â³1-dehydrogenase and 3-ketosteroid-9α-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9α-hydroxy-4-androstene-3,17-dione through the catabolism of sterols
Keywords: AD; 4-androstene-3,17-dione; ADD; 1,4-androstadiene-3,17-dione; 9-OHAD; 9α-hydroxy-4-androstene-3,17-dione; 5α-AD; 5α-androstane-3,17-dione; T; 4-androstene-17β-ol-3-one; 5α-T; 5α-androstane-17β-ol-3-one; 1-(5α)-T; 1-(5α)-androstene-17β-ol-3-one
Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells
Keywords: DGK; diacylglycerol kinase; PA; phosphatidic acid; SF1; steroidogenic factor 1; CYP; cytochrome P450; DAG; diacylglycerol; DHEA; dehydroepiandrosterone; StAR; steroidogenic acute regulatory protein; ASAH1; acid ceramidase; SPHK; sphingosine kinase; PLD; p
Methodological considerations in use of the cortisol/DHEA(S) ratio in adolescent populations
Keywords: Cortisol; DHEA; DHEAS; Ratio; HPA axis; Adolescent; Puberty, Adrenarche;
Interaction of Androst-5-ene-3β,17β-diol and 5α-androstane-3β,17β-diol with estrogen and androgen receptors: A combined binding and cell study
Keywords: ADIOL; androst-5-ene-3β,17β-diol; 3β-DIOL; 5α-androstane-3β,17β-diol; DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; BC; breast cancer; ER; estrogen receptor; E2; estradiol; AR; androgen receptor; E1; estrone; T; testosterone; OH-flu; hydro
Identification of a novel mutation in CYP17A1 gene
Keywords: ACTH; adrenocorticotropic hormone; CAH; congenital adrenal hyperplasia; DHEA; dehydroepiandrosterone; P; progesterone; PCR; polymerase chain reaction; RIA; radioimmunoassay; 17OHD; 17α-hydroxylase/17,20-lyase deficiency; 17OHP; 17-hydroxyprogesterone; 17
Evidence that adrenal hexose-6-phosphate dehydrogenase can effect microsomal P450 cytochrome steroidogenic enzymes
Keywords: H6PDH; hexose-6-phosphate dehydrogenase; G6PDH; glucose-6-phosphate dehydrogenase; ER; endoplasmic reticulum; 11β-HSD1; 11 beta hydroxysteroid dehydrogenase 1; CYP21; 21-hydroxylase; CYP17; 17-hydroxylase; G6P; glucose-6-phosphate; F6P; fructose-6-phosph
7α-Hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in EtC cerebellar neurons
Keywords: DHEA; 3β-hydroxy-5-androstene-17-one (dehydroepiandrosterone); 7OH-DHEA; 7-hydroxy-dehydroepiandrosterone; 11β-HSD1 or 2; 11β-hydroxysteroid dehydrogenase isoform 1 or 2; H6PDH; hexose-6-phosphate dehydrogenase; CORT; corticosterone; 11-dehydro-CORT; 1
Perceived stress at work is associated with attenuated DHEA-S response during acute psychosocial stress
Keywords: DHEA-S; DHEA; Cortisol to DHEA-S ratio; Prolonged stress; Work stress; Acute stress response;
TGFβ1 alters androgenic metabolites and hydroxysteroid dehydrogenase enzyme expression in human prostate reactive stromal primary cells: Is steroid metabolism altered by prostate reactive stromal microenvironment?
Keywords: 6S; cancer-derived primary stromal cells; A-dione; 5α-androstanedione; 5-diol; androstenediol; 4-dione; androstenedione; ANOVA; analysis of variance; AR; androgen receptor; DHEA; dehydroepiandrosterone; DHEA sulfate; DHEAS; DHT; dihydrotestosterone; DMEM
Development, validation and application of a stable isotope dilution liquid chromatography electrospray ionization/selected reaction monitoring/mass spectrometry (SID-LC/ESI/SRM/MS) method for quantification of keto-androgens in human serum
Keywords: A; androsterone; Adione; 5α-androstane-3,17-dione; Î4-AD; Î4-androstene-3,17-dione; ADT; androgen deprivation therapy; CD-FBS; charcoal dextran stripped fetal bovine serum; CRPC; castration resistant prostate cancer; CV; coefficient of variation; DHEA;
Nongenomic bronchodilating action elicited by dehydroepiandrosterone (DHEA) in a guinea pig asthma model
Keywords: DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosterone sulfate; ASM; airway smooth muscle; CCh; carbachol; KCl; potassium chloride; OVA; ovalbumin; NO; nitric oxide; KHS; Krebs-Henseleit bicarbonate solution; BK; bradykinin; Emax; maximal effect;