Keywords: وابسته به پروتئین کیناز وابسته به DNA; AOM; azoxymethane; Apc; adenomatous polyposis coli; CAC; colitis associated cancer; CRC; colorectal cancer; DNA-PK; DNA-dependent protein kinase; GF; germ free; GI; gastrointestinal; IBD; inflammatory bowel diseases; IL; interleukin; MAIT; mucosa-associat
مقالات ISI وابسته به پروتئین کیناز وابسته به DNA (ترجمه نشده)
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Keywords: وابسته به پروتئین کیناز وابسته به DNA; AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se
Keywords: وابسته به پروتئین کیناز وابسته به DNA; HPCs; hepatic progenitor cells; mtROS; mitochondrial reactive oxygen species; DEN; diethylnitrosamine; SPCs; stem/progenitor cells; HSCs; hematopoietic stem cells; NSCs; neural stem cells; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum;
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ATM; ataxia telangiectasia-mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; CI; combination index; CLL; chronic lymphocytic leukemic cells; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit;
Keywords: وابسته به پروتئین کیناز وابسته به DNA; AIM2; absent in melanoma 2; AP-1; activating protein-1; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; AZT; azidothymidine; CCCR5; C-C chemokine receptor type 5; CDK1; cyclin-dependent kinase 1; CXCR4; C-X-C chemokine receptor t
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex
DNA damage, metabolism and aging in pro-inflammatory T cells
Keywords: وابسته به پروتئین کیناز وابسته به DNA; EC; endothelial cell; ROS; reactive oxygen species; ATP; adenosine 5â²-triphosphate; ER; endoplasmic reticulum; mtDNA; mitochondrial DNA; ETC; electron transport chain; mROS; mitochondrial ROS; NADPH; nicotinamide adenine dinucleotide phosphate; TNF-α;
Threonine 454 phosphorylation in Grainyhead-like 3 is important for its function and regulation by the p38 MAPK pathway
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ATF-2; activating transcription factor 2; BLNK; B-cell linker; CaMK; calcium/calmodulin-dependent protein kinase; CDK; cyclin-dependent kinase; CHK; checkpoint kinase; CK; casein kinase; DNAPK; DNA-dependent protein kinase; EPHX3; epoxide hydrolase 3; ERK
Integrating plant and animal biology for the search of novel DNA damage biomarkers
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ARP; actin related protein; ASK; Arabidopsis SPK1-like; At; Arabidopsis thaliana; ATAF; arabidopsis transcription activation factor; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR-interacting protein; BARD; BRCA1-associated RING
RNA polymerase II pausing and transcriptional regulation of the HSP70 expression
Keywords: وابسته به پروتئین کیناز وابسته به DNA; HSP; heat shock protein; HSF1; heat shock factor 1; Pol II; RNA polymerase II; UPR; unfolded protein response; HSE; heat shock element; P-TEFb; positive transcription elongation factor b; PARP; poly(ADP)-ribose polymerase; PAF1; polymerase associated fact
Nanoparticle-mediated knockdown of DNA repair sensitizes cells to radiotherapy and extends survival in a genetic mouse model of glioblastoma
Keywords: وابسته به پروتئین کیناز وابسته به DNA; GBM; glioblastoma; Ape1; apurinic endonuclease 1; DSB; double strand break; BER; base excision repair; siGFP; siRNA against green fluorescent protein; siApe1; siRNA against Ape1; PEI; polyethyleneimine; CTX; chlorotoxin; CP; chitosan-grafted PEG; NP; nano
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho
Autophagy: The spotlight for cellular stress responses
Keywords: وابسته به پروتئین کیناز وابسته به DNA; HSC70; Heat Shock 70KDa protein; AMPK; AMP-activated protein kinase; ATG; autophagy-related genes; Beclin-1; coiled-coil, myosin-like BCL2-interacting protein; CQ; chloroquine; DNA-PK; DNA-dependent protein kinase; FYVE; Fab1, YOTB, Vac1 and EEA1; GFP; gr
Maximising the potential of AKT inhibitors as anti-cancer treatments
Keywords: وابسته به پروتئین کیناز وابسته به DNA; AE; adverse event; CRPC; castrate resistant prostate cancer; DLT; dose limiting toxicity; DNA-PK; DNA-dependent protein kinase; DSB; double strand break; GSK3β; glycogen synthase kinase beta; INPP4B; polyphosphate 4-phosphatase type II; MTD; maximum tole
Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ATR; ataxia telangiectasia and Rad-3 related protein; PIKK; phosphatidylinositol 3-kinase-related protein kinase; ATM; ataxia telangiectasia mutated; mTOR; mammalian target of Rapamycin; DNA-PK; DNA-dependent protein kinase; 3D; three-dimensional; MCL; ma
The ATM kinase inhibitor KU-55933 provides neuroprotection against hydrogen peroxide-induced cell damage via a γH2AX/p-p53/caspase-3-independent mechanism: Inhibition of calpain and cathepsin D
Keywords: وابسته به پروتئین کیناز وابسته به DNA; AIF; apoptosis inducing factor; A-T; ataxia telangiectasia syndrome; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; CGC; cerebellar granule cells; DNA-PK; DNA-dependent protein kinase; Dox; doxorubicin; DSB; doubl
Modulation of ionizing radiation-induced effects by NU7441, KU55933 and VE821 in peripheral blood lymphocytes
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Ionizing radiation; Lymphocytes; KU55933; NU7441; VE821; ATM; ataxia-telangiectasia mutated kinase; ATR; ataxia telangiectasia and Rad3-related protein kinase; DMSO; dimethyl sulfoxide; DNA-PK; DNA-dependent protein kinase; DSB; double strand break; Gy; g
House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs
Keywords: وابسته به پروتئین کیناز وابسته به DNA; House dust mite; asthma; oxidative stress; DNA double-strand breaks; BEAS-2B; cell death; DNA repair; NU7441; AHR; Airway hyperresponsiveness; ATM; Ataxia-telangiectasia mutated; BAL; Bronchoalveolar lavage; CC10; Club cell 10Â kDa protein; DCFH-DA; 2,7-D
TDP-43/FUS in motor neuron disease: Complexity and challenges
Keywords: وابسته به پروتئین کیناز وابسته به DNA; AD; Alzheimer's disease; Ago2; Argonaute 2; ALS; Amyotrophic lateral sclerosis; ALS/PD; amyotrophic lateral sclerosis and Parkinsonism-dementia complex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF3; activating transcription factor 3
Cancer TARGETases: DSB repair as a pharmacological target
Keywords: وابسته به پروتئین کیناز وابسته به DNA; DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel
BRCA1: Beyond double-strand break repair
Keywords: وابسته به پروتئین کیناز وابسته به DNA; BRCA1; Base-excision repair; 8oxoG; 8-oxo-guanine; 8oxodG; 8-hydroxy-2â²-deoxyguanosine; AP; apurinic/apyrimidinic; APE1 (or APE1/REF1); AP-endonuclease (redox effector factor-1); ATR; ataxia telangiectasia and Rad3 related; ATM; ataxia telangiectasia mu
DNA mismatch repair enzymes: Genetic defects and autoimmunity
Keywords: وابسته به پروتئین کیناز وابسته به DNA; AA; aplastic anemia; ARS; aminoacyl tRNA synthetase; CMMR-D; constitutional mismatch repair-deficiency syndrome; DM; dermatomyositis; DM1; myotonic dystrophy type I; DNA-PKcs; DNA-dependent protein kinase; ELISA; enzyme-linked immunosorbent assay; HD; Hun
Resveratrol induces DNA damage in colon cancer cells by poisoning topoisomerase II and activates the ATM kinase to trigger p53-dependent apoptosis
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ab; antibody; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3 related; DAPI; 4â²,6-diamidino-2-phenylindole; DNA-PK; DNA-dependent protein kinase; DOX; doxorubicin; ERK1/2; extracellular signal-regulated kinase 1/2; H2AX; histone
XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency
Keywords: وابسته به پروتئین کیناز وابسته به DNA; DNA double-strand break repair; nonhomologous end-joining; double-strand break repair deficiency; XRCC4/LIG4; immunodeficiency; microcephaly; CID; Combined immunodeficiency; CS; Cockayne syndrome; CSR; Class-switch recombination; DNA-PK; DNA-dependent pro
Cadmium delays non-homologous end joining (NHEJ) repair via inhibition of DNA-PKcs phosphorylation and downregulation of XRCC4 and Ligase IV
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Heavy metal cadmium (Cd); DNA damage repair (DDR); Non-homologous end joining (NHEJ); DNA-dependent protein kinase; X-ray cross-complementing protein 4; DNA Ligase IV;
The Nuclear Factor κB pathway: A link to the immune system in the radiation response
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Nuclear Factor κB; Immune system; Cellular radiation response; Linear energy transfer; Bystander effect; Chemokines; A20 (TNFAIP3); tumor necrosis factor inducible protein 3; ARD; ankyrin repeat domain; ATM; ataxia telangiectasia mutated protein; β-TrCP
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis
Keywords: وابسته به پروتئین کیناز وابسته به DNA; DNA-dependent protein kinase; Non-homologous end joining; Mitosis; ATM; ataxia telangiectasia mutated; ATR; ATM- and Rad3-related; ds; double-stranded; cryo-EM; cryo-electron microscopy; DSB; DNA double strand break; DNA-PK; DNA-activated/dependent protei
mTOR signaling in tumorigenesis
Keywords: وابسته به پروتئین کیناز وابسته به DNA; mTOR; the mechanistic target of rapamycin or the mammalian target of rapamycin; PIKK; phosphoinositide 3-kinase related protein kinase; ATM; ataxia-telangiectasia mutated; ATR; ataxia-telangiectasia and rad3-related; DNAPK; DNA-dependent protein kinase; R
Distinct functions of steroidogenic factor-1 (NR5A1) in the nucleus and the centrosome
Keywords: وابسته به پروتئین کیناز وابسته به DNA; CDK2; cyclin-dependent kinase 2; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; SF-1; Steroidogenic Factor 1 NR5A1, Ad4BP; SUMO; small ubiquitin like modifier; MT; microtubule; SF-1; Adrenal; Gonad; Centros
Inhibition of constitutive Akt (PKB) phosphorylation by docosahexaenoic acid in the human breast cancer cell line MDA-MB-453
Keywords: وابسته به پروتئین کیناز وابسته به DNA; PUFA; polyunsaturated fatty acid; RTK; receptor tyrosine kinase; FGFR; fibroblast growth factor receptor; IGFR; insulin-like growth factor receptor; PDK1; phosphoinositide-dependent kinase 1; mTOR; mammalian target of rapamycin; PDGF; platelet-derived gro
DNA doubleâstrand break response in stem cells: Mechanisms to maintain genomic integrity
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; BRCA1; breast cancer type 1 susceptibility protein; CtBP; C-terminal binding protein; CtIP; CTBP interacting protein; DDR; DNA damage response; DNA-PK; DNA-dependent
Novel Survivin Inhibitor YM155 elicits Cytotoxicity in Glioblastoma Cell Lines with Normal or Deficiency DNA-Dependent Protein Kinase Activity
Keywords: وابسته به پروتئین کیناز وابسته به DNA; glioblastoma; DNA-dependent protein kinase; securin; surviving; YM155
Intranuclear Delivery of a Novel Antibody-Derived Radiosensitizer Targeting the DNA-Dependent Protein Kinase Catalytic Subunit
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Radiosensitization; scFv; DNA-dependent protein kinase; Folate-mediated delivery; Nonhomologous end joining; DNA repair;
Transcriptional regulation by post-transcriptional modification-Role of phosphorylation in Sp1 transcriptional activity
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Akt; protein kinase B; AT1R; angiotensin II type 1 receptor; ATM; ataxia telangiectasia-mutated protein kinase; CDK; cyclin-dependent kinase; CK-II; casein kinase-II; DNA-PK; DNA-dependent protein kinase; EBV; Epstein-Barr virus; EGF; epidermal growth fac
Regulation and protection of mitochondrial physiology by sirtuins
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Acetyl-CoA; acetyl-coenzyme A; AceCS2; acetyl-coenzyme A synthethase 2; ACC; Acetyl-CoA carboxylase; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; 5â² adenosine monophosphate-activated protein kinase; ANT; adenine nucleotide transloca
Janus kinase 2 - A novel negative regulator of estrogen receptor α function
Keywords: وابسته به پروتئین کیناز وابسته به DNA; CA; constitutive active; CDK2; Cyclin dependent kinase 2; CDK7; Cyclin dependent kinase 7; CK2; Casein kinase 2; DCC; dextran-coated charcoal-treated; DNA-PK; DNA-dependent protein kinase; E2; 17β-estradiol; EGFR; Epidermal growth factor receptor; ER; es
microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling
Keywords: وابسته به پروتئین کیناز وابسته به DNA; miRNA; microRNA; EGFR; epidermal growth factor receptor; PI3K; phosphatidyl inositide 3 kinase; DNA-PKcs; DNA-dependent protein kinase; microRNA-7; EGFR; PI3K; Akt; Radiosensitivity;
Choosing the right path: Does DNA-PK help make the decision?
Keywords: وابسته به پروتئین کیناز وابسته به DNA; a-NHEJ; alternative non-homologous end joining; B-NHEJ; backup non-homologous end joining; c-NHEJ; classical non-homologous end joining; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent kinase catalytic subunit; DSB; double strand break; HR;
Poly(ADP-Ribose) Polymerase-1 and DNA-Dependent Protein Kinase Have Equivalent Roles in Double Strand Break Repair Following Ionizing Radiation
Keywords: وابسته به پروتئین کیناز وابسته به DNA; DNA-dependent protein kinase; Poly(ADP-ribose) polymerase; Ionizing radiation; double strand break repair;
Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Nonhomologous end joining; Calicheamicin; Chromosome aberrations; DNA-dependent protein kinase
Ku, Artemis, and ataxia-telangiectasia-mutated: Signalling networks in DNA damage
Keywords: وابسته به پروتئین کیناز وابسته به DNA; AT; ataxia-telangiectasia; ATM; ataxia-telangiectasia-mutated; ATR; ataxia-telangiectasia and Rad3-related; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; catalytic subunit of DNA-dependent protein kinase; DSBs; double-strand breaks; ROS; reactive oxygen
Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo
Keywords: وابسته به پروتئین کیناز وابسته به DNA; TR; T cell receptor; Ig; immunoglobulin; RSS; recombination signal sequence; SE; signal end; CE; coding end; SJ; signal joint; CJ; coding joint; NHEJ; non-homologous end joining; DSB; double strand break; TdT; terminal nucleotidyl transferase; DNA-PK; DNA
Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase η-deficient human cells treated with cisplatin and oxaliplatin
Keywords: وابسته به پروتئین کیناز وابسته به DNA; ICL; interstrand crosslink; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR interacting protein; PIKK; PI-3 kinase-related protein kinase; DNA-PK; DNA-dependent protein kinase; Polη; DNA polymerase η; RPA; replication protein A
DNA end joining activity is reduced in Alzheimer's disease
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Alzheimer's disease; DNA damage; DNA repair; DNA-dependent protein kinase; DNA end joining; Non-homologous end joining; Cerebral cortex
Heat shock induces phosphorylation of histone H2AX in mammalian cells
Keywords: وابسته به پروتئین کیناز وابسته به DNA; Heat shock; Double-strand breaks; γ-H2AX; Ataxia telangiectasia mutated; DNA-dependent protein kinase;
Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break-inducing agents
Keywords: وابسته به پروتئین کیناز وابسته به DNA; DNA-dependent protein kinase; G2/M checkpoints; Ionizing radiation; Accelerated nitrogen ions; Bleomycin;
Sirtuins (histone deacetylases III) in the cellular response to DNA damage-Facts and hypotheses
Keywords: وابسته به پروتئین کیناز وابسته به DNA; CBP; CREB-binding protein; DNA-PK; DNA-dependent protein kinase; DSB; DNA double strand break; FOXO; forkhead box class O; Gadd45; growth arrest and DNA damage response gene; HAT; histone acetyltransferase; HDAC; histone deacetylase; Mn-SOD; manganese sup
Heterogeneous nuclear ribonucleoprotein B1 protein impairs DNA repair mediated through the inhibition of DNA-dependent protein kinase activity
Keywords: وابسته به پروتئین کیناز وابسته به DNA; RNA binding protein; RNA splicing; hnRNP B1; DNA-dependent protein kinase; DNA double-strand break repair; Lung cancer;
The role of SMG-1 in nonsense-mediated mRNA decay
Keywords: وابسته به پروتئین کیناز وابسته به DNA; NMD; nonsense-mediated mRNA decay; EJC; exon-junction complex; PTC; premature translation termination codon; IC; initial SMG-1-Upf1 complex; PIKK; phosphoinositide 3-kinase related kinase; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3 related;
Sp1: Regulation of gene expression by phosphorylation
Keywords: وابسته به پروتئین کیناز وابسته به DNA; CCSP; Clara cell secretary protein; CDK; cyclin-dependent kinase; CK-II; casein kinase-II; CRH; corticotropin-releasing hormone; DNA-PK; DNA-dependent protein kinase; EGF; epidermal growth factor; ERK; extracellular signal-regulated kinase; FGF-2; fibrobl