دانلود مقالات ISI درباره مطالعات داکینگ + ترجمه فارسی

2-Aminothiazole derivatives as antimycobacterial agents: Synthesis, characterization, in vitro and in silico studies

Keywords: مطالعات داکینگ; Mycobacterium tuberculosis; Tuberculosis; 2-Aminothiazole; Drug like molecule; β-Ketoacyl-ACP Synthase; Docking studies; AFUHQKWBXCCDKC-UHFFFAOYSA-N; LOMSSLWUSYZMFI-UHFFFAOYSA-N; ZYCLZXHOEKNHLJ-UHFFFAOYSA-N; CFURRSHMJJMLMZ-UHFFFAOYSA-N; WEMHZNKBYVECDZ-UH

دانلود رایگان متن کامل مقاله ISI 81 صفحه سال انتشار : 2014 سفارش ترجمه

Curcumin-I Knoevenagel's condensates and their Schiff's bases as anticancer agents: Synthesis, pharmacological and simulation studies

Keywords: مطالعات داکینگ; Anticancer agents; Curcumin-I derivatives; Docking studies; DNA binding and hemolysis and cell line profiles;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Insights into potentially toxic effects of 4-aminoantipyrine on the antioxidant enzyme copper-zinc superoxide dismutase

Keywords: مطالعات داکینگ; Antioxidant enzyme; Multi-spectroscopic techniques; Docking studies; Toxicity evaluation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Solvent free synthesis, crystal studies, docking studies and antibacterial properties of some novel fluorinated pyridazinone derivatives

Keywords: مطالعات داکینگ; Organofluorine compounds; Microwave synthesis; Docking studies; Antibacterial studies; X-ray crystal studies;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Multispectroscopic methods reveal different modes of interaction of anti cancer drug mitoxantrone with Poly(dG-dC).Poly(dG-dC) and Poly(dA-dT).Poly(dA-dT)

Keywords: مطالعات داکینگ; Drug-DNA interactions; Anticancer drug mitoxantrone; Poly(dG-dC).Poly(dG-dC) and Poly(dA-dT).Poly(dA-dT); Absorbance and fluorescence; Circular dichroism; Docking studies

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

Keywords: مطالعات داکینگ; (Coumarin-3-yl)carbamate scaffold; Monoamine oxidase (MAO); In vitro assays; In vivo assays; ADME properties; Docking studies

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Flavonoids and Polymer Derivatives as CYP3A4 Inhibitors for Improved Oral Drug Bioavailability

Keywords: مطالعات داکینگ; oral bioavailability; drug delivery; polymers; CYP3A4 inhibitors; computational molecular modeling; cytochrome P450; computer aided drug design; docking studies; drug metabolism; kinetics;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Rational design, efficient syntheses and biological evaluation of N,N′-symmetrically bis-substituted butylimidazole analogs as a new class of potent Angiotensin II receptor blockers

Keywords: مطالعات داکینگ; AT1 receptor blockers; N,N′-Bis-alkylated butylimidazole analogs; Synthesis; Wittig reaction; Hydroxymethylation; Structure elucidation; Docking studies; Molecular dynamics; Biological evaluation

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis, pharmacological evaluation and docking studies of N-(benzo[d]thiazol-2-yl)-2-(piperazin-1-yl)acetamide analogs as COX-2 inhibitors

Keywords: مطالعات داکینگ; Anti-inflammatory activity; Docking studies; Ulcerogenic activity; 2-Amino benzothiazole; Piperazine; Computer aided drug design;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Regioselective synthesis and antimicrobial studies of ester linked 1,4-disubstituted 1,2,3-bistriazoles

Keywords: مطالعات داکینگ; Click chemistry; 1,4-Disubstituted 1,2,3-triazoles; Antibacterial activity; Antifungal activity; Docking studies;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and evaluation of novel 2-pyridone derivatives as inhibitors of phosphodiesterase3 (PDE3): A target for heart failure and platelet aggregation

Keywords: مطالعات داکینگ; Baylis-Hillman acetates; Enamines; 2-Pyridone derivatives; PDE3 inhibition; Docking studies; Leads;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis of tetra-substituted pyrroles, a potential phosphodiesterase 4B inhibitor, through nickel(II) chloride hexahydrate catalyzed one-pot four-component reaction

Keywords: مطالعات داکینگ; Multicomponent reactions; β-Ketoesters; Nickel(II) chloride hexahydrate; Tetra-substituted pyrroles; Docking studies; Phosphodiesterase 4B inhibitor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Structural insights regarding an insecticidal Talisia esculenta protein and its biotechnological potential for Diatraea saccharalis larval control

Keywords: مطالعات داکینگ; Reserve protein; Insecticidal activity; Binding sites; Homology modeling; Docking studies;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis, biological assay in vitro and molecular docking studies of new Schiff base derivatives as potential urease inhibitors

Keywords: مطالعات داکینگ; Competitive inhibition; Docking studies; Electrostatic potential; Schiff base; Thiourea derivatives; Urease inhibition;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Aryl piperazine and pyrrolidine as antimalarial agents. Synthesis and investigation of structure-activity relationships

Keywords: مطالعات داکینگ; Piperazine; Pyrrolidine; Antiplasmodial; Plasmodium; Antimalarial agents; Docking studies;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Interaction mechanism between 4-aminoantipyrine and the enzyme lysozyme

Keywords: مطالعات داکینگ; 4-Aminoantipyrine; Lysozyme; Multi-spectroscopic techniques; Docking studies; Toxicity evaluation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors

Keywords: مطالعات داکینگ; Peptidomimetics; Falcipain-2 inhibitors; Cysteine proteases; Docking studies;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Docking studies and effects of syn-anti isomery of oximes derived from pyridine imidazol bicycled systems as potential human acetylcholinesterase reactivators

Keywords: مطالعات داکینگ; acetylcholinesterase; docking studies; oximes; neurotoxic agents; theoretical calculation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis and docking studies of quinoline-oxazolidinone hybrid molecules and their antitubercular properties

Keywords: مطالعات داکینگ; 4-Aminoquinoline; Oxazolidinone; Antibacterial; Antimycobacterial activity; Docking studies

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Acetylcholinesterase inhibitors from the toadstool Cortinarius infractus

Keywords: مطالعات داکینگ; Alzheimer’s disease; β-Carbolines; Fungi; Docking studies

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents

Keywords: مطالعات داکینگ; Pyrrole derivatives; pyrrolo[2,3-d]pyrimidines; Pyrrolotriazolopyrimidines, pyrrolotetrazolopyrimidines; Synthesis; Docking studies; MIC; Antimicrobial

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Structural determinants of resveratrol for cell proliferation inhibition potency: Experimental and docking studies of new analogs

Keywords: مطالعات داکینگ; Resveratrol; Polymethoxy-stilbenes; Tubulin polymerization; Colon cancer; Docking studies

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors

Keywords: مطالعات داکینگ; Histone deacetylase; Ring closing metathesis reaction; Anticancer drugs; Docking studies; 4-aba; 4-allyloxybenzaldehyde; 4-Pea; 4-pentenoic acid; 6-Epa; 6-eptenoic acid; BAP; borane-pyridine complex; Boc; tert-butyloxycarbonyl; DCM; dichloromethane; DIC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis, anti-inflammatory evaluation and docking studies of some new fluorinated fused quinazolines

Keywords: مطالعات داکینگ; Fluorinated quinazolines; Cyclooxygenase; Anti-inflammatory activity; Docking studies

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular basis of the interaction of novel tributyltin(IV) 2/4-[(E)-2-(aryl)-1-diazenyl]benzoates endowed with an improved cytotoxic profile: Synthesis, structure, biological efficacy and QSAR studies

Keywords: مطالعات داکینگ; Tributyltin(IV) compounds; Arylazobenzoate; Spectroscopy; X-ray crystallography; Cell lines; Anti-cancer drugs; Hydrophobicity; QSAR; Docking studies

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17α-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure

Keywords: مطالعات داکینگ; Prostate cancer; 17α-Hydroxylase-17,20-lyase (CYP17) inhibitors; Steroidomimetics; Hepatic CYPs; Pharmacokinetic studies; Testosterone plasma concentrations; Docking studies; Molecular electrostatic potential maps

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

Design and synthesis of sulfoximine based inhibitors for HIV-1 protease

Keywords: مطالعات داکینگ; HIV protease; HAART; Sulfoximine; Transition state mimic; Indinavir; Docking studies; Crystallographic water; TSM binding

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17

Keywords: مطالعات داکینگ; Prostate cancer; 17α-hydroxylase-17,20-lyase (CYP17) inhibitors; Steroidomimetics; Hepatic CYPs; Docking studies

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

In silico prediction of novel phosphodiesterase type-5 inhibitors derived from Sildenafil, Vardenafil and Tadalafil

Keywords: مطالعات داکینگ; PDE-5 inhibitors; MIA-QSAR; Docking studies; Erectile dysfunction

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Novel anti-HIV cyclotriazadisulfonamide derivatives as modeled by ligand- and receptor-based approaches

Keywords: مطالعات داکینگ; Anti-HIV compounds; CD4 receptor; MIA-QSAR; Docking studies

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Conformationally locked thiosugars as potent α-mannosidase inhibitors: Synthesis, biochemical and docking studies

Keywords: مطالعات داکینگ; Thiosugars; Inhibition; α-Mannosidase; Docking studies;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Homology model of 1α,25-dihydroxyvitamin D3 24-hydroxylase cytochrome P450 24A1 (CYP24A1): Active site architecture and ligand binding

Keywords: مطالعات داکینگ; CYP24; Homology model; MOE; 1,25-Dihydroxyvitamin D3; Docking studies; Inhibitor interactions

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis, docking studies and anti-inflammatory activity of 4,5,6,7-tetrahydro-2H-indazole derivatives

Keywords: مطالعات داکینگ; Tetrahydro-2H-indazoles; Anti-inflammatory activity; Docking studies

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi

Keywords: مطالعات داکینگ; Thiosemicarbazones; Acyl-hydrazones; Aminoacyl-thiazolidones; Anti-Trypanosoma cruzi compounds; Docking studies

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-Substituted P1/P1′ side chains

Keywords: مطالعات داکینگ; HIV-1 protease inhibitors; Microwave; High-speed synthesis; 3D QSAR CoMFA; Palladium; Catalysis; Docking studies

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه