دانلود مقالات ISI درباره dt40 + ترجمه فارسی

SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus

Keywords: dt40; AID; DT40; Gene conversion; Ig; Somatic hypermutation; SRSF1; AID; activation-induced cytidine deaminase; AIDΔC; C-terminal 10 amino acid-deleted AID; CSR; class switch recombination; GCV; gene conversion; IgV; immunoglobulin variable region; NES; nuclea

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells

Keywords: dt40; B cell development; DT40; Epigenetics; Gene targeting; Histone acetyltransferase; Bach2; BTB and CNC homology 2; Bcl-6; B cell lymphoma-6; Blimp-1; B lymphocyte-induced maturation protein-1; ChIP; chromatin immunoprecipitation; EBF1; early B cell factor 1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Topoisomerase I deficiency causes RNA polymerase II accumulation and increases AID abundance in immunoglobulin variable genes

Keywords: dt40; DT40; Topoisomerase I; RNA polymerase II; Activation-induced deaminase; Somatic hypermutation; Gene conversion;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Protein kinase Cθ gene expression is oppositely regulated by GCN5 and EBF1 in immature B cells

Keywords: dt40; 5′-RACE; 5′-rapid amplification of cDNA ends; BCR; B cell receptor; ChIP; chromatin immunoprecipitation; EBF1; early B cell factor 1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; H3K14; Lys-14 of histone H3; H3K9; Lys-9 of histone H3; HAT; histone

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Analysis of SHPRH functions in DNA repair and immunoglobulin diversification

Keywords: dt40; SHPRH; PCNA; Ubiquitin; DNA repair; DT40;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction

Keywords: dt40; PD; Parkinson's disease; ROS; reactive oxygen species; H2O2; hydrogen peroxide; carboxy-H2DCFDA; 5-(and-6)-carboxy-2′,7′-dichloro-dihydrofluorescein diacetate; AV; Annexin-V; PI; propium iodide; TMRE; tetramethylrhodamine ethyl ester; CCCP; carbonyl c

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial Ca2+ signals in autophagy

Keywords: dt40; mTOR; mammalian target of rapamycin; InsP3R; inositol 1,4,5-trisphosphate receptor; AMPK; adenosine monophosphate activated protein kinase; mTORC1; mammalian target of rapamycin complex 1; GAP; GTPase activating protein; TSC1/TSC2; tuberous sclerosis comp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

SUMO ligase activity of vertebrate Mms21/Nse2 is required for efficient DNA repair but not for Smc5/6 complex stability

Keywords: dt40; SMC proteins; Nse2; DNA repair; DT40; SUMO ligase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells

Keywords: dt40; HERC2; RNF8; RNF168; Ubiquitin; DT40

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

The role of SNM1 family nucleases in etoposide-induced apoptosis

Keywords: dt40; Apoptosis; SNM1A; APOLLO; ARTEMIS; NHEJ; DT40

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Functional relationship between Claspin and Rad17

Keywords: dt40; Claspin; Rad17; DT40; DNA replication;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Oncogenicity of L-type amino-acid transporter 1 (LAT1) revealed by targeted gene disruption in chicken DT40 cells: LAT1 is a promising molecular target for human cancer therapy

Keywords: dt40; CD98hc; CD98lc; DT40; Gene disruption; LAT1; siRNA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs

Keywords: dt40; BCR, B cell receptor; O2−, superoxide; PKC, protein kinase C; PMA, phorbol 12-myristate 13-acetateHelios; Apoptosis; Superoxide; Protein kinase C; DT40; Gene targeting

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Species-specific 5′-genomic structure and multiple transcription start sites in the chicken Pax5 gene

Keywords: dt40; iMet, initiation methionine; Pax5, paired box 5; RACE, rapid amplification of cDNA-ends; RT, reverse transcription; TSS, transcription start sitePax5; DT40; B cell; Chicken

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Mutant cells defective in DNA repair pathways provide a sensitive high-throughput assay for genotoxicity

Keywords: dt40; Genotoxicity assay; DNA repair; DT40; DNA damage; High-throughput screening

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Telomere biology of the chicken: A model for aging research

Keywords: dt40; Telomere; Telomerase; Mega-telomeres; Splice variants; TERT; TR; DF-1; DT40; Reconstitution of telomerase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD2

Keywords: dt40; DT40; Mn-SOD; Cell cycle; SOD2; ROS; SOD1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Lacking of Aiolos accelerates pre-mature B cell apoptosis mediated by BCR signaling through elevation in cytochrome c release

Keywords: dt40; BCR; B cell receptor; GAPDH; glyceraldehydephosphate dehydrogenase; PAGE; polyacrylamide gel electrophoresis; PI; propidium iodide; PMA; phorbol 12-myristate 13-acetate; PVDF; polyvinyliden difluoride; RT-PCR; reverse transcription-polymerase chain reacti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Expression profiling of chicken DT40 lymphoma cells indicates clonal selection of knockout and gene reconstituted cells

Keywords: dt40; Bruton’s tyrosine kinase; B cells; Expression profiling; DT40; X-linked agammaglobulinemia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion

Keywords: dt40; ASCIZ; ATMIN; DT40; Base excision repair; Immunoglobulin gene conversion; DNA polymerase β; Genetics

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Cell sorting analysis of cell cycle-dependent X-ray sensitivity in end joining-deficient human cells

Keywords: dt40; Flow cytometry; Cell sorter; Cell cycle; DNA double-strand breaks; Nonhomologous end joining; X-ray sensitivity; DT40; Nalm-6

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase IIIα

Keywords: dt40; RECQL1; RECQL5; BLM; RECQ; DT40

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

AID-mediated diversification within the IgL locus of chicken DT40 cells is restricted to the transcribed IgL gene

Keywords: dt40; Somatic hypermutation; Gene conversion; Immunoglobulin; DT40

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

GCN5 and BCR signalling collaborate to induce pre-mature B cell apoptosis through depletion of ICAD and IAP2 and activation of caspase activities

Keywords: dt40; BCR; B cell receptor; HAT; histone acetyltransferase; PMA; phorbol 12-myristate 13-acetate; PVDF; polyvinyliden difluoride.; Caspase; DT40; Gene targeting; NF-κB; PKC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Bipartite nuclear localization signal of matrin 3 is essential for vertebrate cells

Keywords: dt40; Matrin 3; Nuclear import; Nuclear localization signal; DT40; RNAi; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage

Keywords: dt40; DNA repair gene; Homologous recombination; Single nucleotide polymorphism; DT40; Cancer risk; Cisplatin; RAD51; XRCC2; XRCC3

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

WRN counteracts the NHEJ pathway upon camptothecin exposure

Keywords: dt40; RecQ; WRN; Ku70; DNA-PKcs; DT40; BLM; CPT; TopI; Etoposide; PARP-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

DDB1 gene disruption causes a severe growth defect and apoptosis in chicken DT40 cells

Keywords: dt40; DDB1; DT40; Conditional knockout; Cell viability; Apoptosis; Cell cycle arrest

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Calcium mobilization via type III inositol 1,4,5-trisphosphate receptors is not altered by PKA-mediated phosphorylation of serines 916, 934, and 1832

Keywords: dt40; Inositol 1,4,5-trisphosphate receptor; cAMP-dependent protein kinase; Phosphorylation; Calcium mobilization; DT40

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

ERK binds, phosphorylates InsP3 type 1 receptor and regulates intracellular calcium dynamics in DT40 cells

Keywords: dt40; IP3R1; ERK1/2; DT40; FRET; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Rapid assessment of two major repair activities against DNA double-strand breaks in vertebrate cells

Keywords: dt40; DNA double-strand break; Non-homologous end joining; Homologous recombinational repair; Single-strand annealing; DT40

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Epitope Tagging of Proteins at the Native Chromosomal Loci of Genes in Mice and in Cultured Vertebrate Cells

Keywords: dt40; ES, embryonic stem; CLEP, chromosomal locus epitope; TAP, tandem affinity purificationepitope tagging; DT40; spliceosome; snRNPs; mass spectrometry

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks

Keywords: dt40; 53BP1; Non-homologous end joining; Ku; Artemis; DT40; Genetics

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Differential usage of non-homologous end-joining and homologous recombination in double strand break repair

Keywords: dt40; DSB; HR; NHEJ; Ku70; DT40

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Regulation of cytokinesis by mgcRacGAP in B lymphocytes is independent of GAP activity

Keywords: dt40; mgcRacGAP; Small GTPase; Cytokinesis; DT40

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Histone acetyltransferase 1 is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells

Keywords: dt40; HAT1; H4 acetylation; DNA repair; DT40; Camptothecin; Methyl methanesulfonate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Analyses of the interaction of WRNIP1 with Werner syndrome protein (WRN) in vitro and in the cell

Keywords: dt40; WRN; Mgs1; WRNIP1; RecQ; FEN1; DT40; Polδ

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line

Keywords: dt40; DT40; Immunoglobulin gene; Hypermutation; Gene conversion; Antibody; Activation-induced cytidine deaminase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes

Keywords: dt40; BrdUrd; 5-bromodeoxyuridine; FACS; fluorescence-activated cell sorting; FITC; fluorescein isothiocyanate-conjugated tyamide; GAPDH; glyceraldehydephosphate dehydrogenase; HAT; histone acetyltransferase; HDAC; histone deacetylase; PCR; polymerase chain rea

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه