EGFR mutated non-small cell lung cancer patients: More prone to development of bone and brain metastases?
Keywords: NSCLC; EGFR; KRAS; Brain metastases; Bone metastases; Survival;
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EGFR mutational genotyping of liquid based cytology samples obtained via fine needle aspiration (FNA) at endobronchial ultrasound of non-small cell lung cancer (NSCLC)
Keywords: Epidermal growth factor receptor; Non-small cell lung carcinoma; Endobronchial ultrasound guided fine needle aspiration; Fine needle aspiration; Lung cancer; Targeted therapy; ALK; anaplastic lymphoma kinase; ASPCR; allele specific polymerase chain reacti
Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies
Keywords: B2M; beta-2-microglobulin; EGFR; epidermal growth factor receptor; ES; embryonic stem; Fab; fragment of antigen binding; Fc; fragment crystallizable; FCGRT; Fc receptor IgG alpha chain transporter; FcRn; neonatal Fc receptor; HSA; human serum albumin; Ig;
The complex understanding of Annexin A1 phosphorylation
Keywords: Annexin A1; ANXA1; Phosphorylation; PKC; EGFR; PKA;
Hepassocin activates the EGFR/ERK cascade and induces proliferation of L02 cells through the Src-dependent pathway
Keywords: HPS; EGFR; Transactivation; ERK; Src;
HER4 selectively coregulates estrogen stimulated genes associated with breast tumor cell proliferation
Keywords: 4ICD; HER4 intracellular domain; BSA; bovine serum albumin; cDNA; complementary DNA; cRNA; complementary RNA; CS-FBS; charcoal stripped fetal bovine serum; Cy3; cyanine 3; Cy5; cyanine 5; EGFR; epidermal growth factor receptor; ER; estrogen receptor alpha
Influence of epidermal growth factor receptor expression on the cetuximab and panitumumab response rates of head and neck carcinoma cells
Keywords: HNSCC; EGFR; Knockdown; Cetuximab; Panitumumab;
Quality of Life is Improved and Kidney Function Preserved in Patients with Nephropathic Cystinosis Treated for 2 Years with Delayed-Release Cysteamine Bitartrate
Keywords: AE; Adverse event; BMI; Body mass index; DR-CYS; Delayed-release cysteamine bitartrate; eGFR; Estimated glomerular filtration rate; PD; Pharmacodynamics; PedsQL; Pediatric Quality of Life Inventory; PK; Pharmacokinetics; WBC [cystine]; White blood cell co
Variable expression of the forgotten oncogene E5 in HPV-positive oropharyngeal cancer
Keywords: Viral oncogene; E5; Human papillomavirus; Oropharyngeal cancer; EGFR;
Comparison of clinical characteristics between patients with ALK-positive and EGFR-positive lung adenocarcinoma
Keywords: Lung adenocarcinoma; EML4-ALK; EGFR; Bronchoscopy;
Impact of urine concentration adjustment method on associations between urine metals and estimated glomerular filtration rates (eGFR) in adolescents
Keywords: BMI; body mass index; C2C; Cuida tu Corazón (Take Care of your Heart); CV; coefficient of variation; DRC-ICP-MS; dynamic reaction cell inductively coupled plasma-mass spectrometer; eGFR; estimated glomerular filtration rate; HNO3; nitric acid; IQC; inter
Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling
Keywords: 10-HDA; 10-hydroxy-2-decenoic acid; BSA; Bovine Serum Albumin; dRoyalactin; deglycosylated royalactin; dsRNA; double-stranded RNA; EGFR; epidermal growth factor receptor; hRoyalactin; heat-treated royalactin; MRJP1; Major Royal Jelly Protein 1 (royalactin
Improved glomerular filtration rate estimation using New equations combined with standardized cystatin C and creatinine in Chinese adult chronic kidney disease patients
Keywords: eGFR; estimated glomerular filtration rate; CKD-EPI; Chronic Kidney Disease Epidemiology Collaboration; CKD; chronic kidney disease; MDRD; Modification of Diet in Renal Disease; Scr; serum creatinine; ScysC; serum cystatin C; CysC; cystatin C; DTPA; dieth
Autophagy regulation in pancreatic acinar cells is independent of epidermal growth factor receptor signaling
Keywords: Autophagy; EGFR; Acute pancreatitis; SPINK1/Spink3;
The human cathelicidin LL-37 enhances airway mucus production in chronic obstructive pulmonary disease
Keywords: Cathelicidins; COPD; Mucins; Mucous overproduction; EGFR; TACE;
Multiplex detection of KRAS mutations by a matrix-assisted laser desorption/ionization-time of flight mass spectrometry assay
Keywords: KRAS mutation; EGFR; RFMP; KRAS mutation testing;
p38-Mediated phosphorylation of Eps15 endocytic adaptor protein
Keywords: CME; clathrin-mediated endocytosis; EGFR; epidermal growth factor receptor; Eps15; EGFR pathway substrate 15; TAK1; transforming growth factor-β-activated kinase 1; TAB1; TAK1-binding protein 1; TNF-α; tumor necrosis factor-α; UIM; ubiquitin-interactin
Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib
Keywords: EGFR; AMPK; Erlotinib; Lung cancer; Xenograft models;
RASSF3 downregulation increases malignant phenotypes of non-small cell lung cancer
Keywords: Non-small cell lung cancer; Lymph node metastasis; Pleural invasion; Tumor suppressor; RASSF3; EGFR;
Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model
Keywords: Lung cancer; Oncogene addiction; EGFR; JAK2; STAT3; Transgenic mice;
The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines
Keywords: HPV; HNSCC; EGFR; PARP; Chk1; Radiosensitivity;
Clinical Outcome With Platinum-Based Chemotherapy in Patients With Advanced Nonsquamous EGFR Wild-Type Non–Small-Cell Lung Cancer Segregated According to KRAS Mutation Status
Keywords: ALK; EGFR; KRAS; Non–small-cell lung cancer; Platinum-based chemotherapy
Fluctuations in eGFR in relation to unenhanced and enhanced MRI and CT outpatients
Keywords: Fluctuations; Outpatients; eGFR; CIN; Iodine-based contrast media; Gadolinium-based contrast media
ReviewDiagnosis and Predictive Molecular Analysis of Non-Small-Cell Lung Cancer in the Africa-Middle East Region: Challenges and Strategies for Improvement
Keywords: Adenocarcinoma; ALK; Biomarker; EGFR; Molecular testing;
Fibroblast Growth Factor-23 in Obese, Normotensive Adolescents Is Associated with Adverse Cardiac Structure
Keywords: BMI; Body mass index; BP; Blood pressure; CKD; Chronic kidney disease; CV; Cardiovascular; DTI; Diastolic time interval; eGFR; Estimated glomerular filtration rate; FGF23; Fibroblast growth factor-23; hsCRP; High-sensitivity C-reactive protein; LADI; Left
Refining risk stratification for locoregional failure after chemoradiotherapy in human papillomavirus-associated oropharyngeal cancer
Keywords: Oropharyngeal cancer; HPV; EGFR; FDG-PET; Local-regional failure; Risk stratification
Combined heart-kidney transplant improves post-transplant survival compared with isolated heart transplant in recipients with reduced glomerular filtration rate: Analysis of 593 combined heart-kidney transplants from the United Network Organ Sharing Datab
Keywords: 34; eGFR; estimated glomerular filtration rate; HKTx; combined heart-kidney transplant; HTx; heart transplant; LVAD; left ventricular assist device; UNOS; United Network for Organ Sharing;
Renal function largely influences Galectin-3 prognostic value in heart failure
Keywords: CKD-EPI; chronic kidney disease-epidemiology equation; CI; confidence interval; eGFR; estimated glomerular filtration rate; Gal-3; Galectin-3; HF; heart failure; HR; hazard ratio; IQR; interquartile range; LVEF; left ventricular ejection fraction; NYHA; N
Renin-angiotensin system inhibition is not associated with increased sudden cardiac death, cardiovascular mortality or all-cause mortality in patients with aortic stenosis
Keywords: AS; aortic stenosis; ACE; angiotensin-converting enzyme; ARB; angiotensin receptor blockade; AVAI; aortic valve area index; AVR; aortic valve replacement; eGFR; estimated glomerular filtration rate; LDL; low density lipoprotein; HDL; high density lipoprot
Mutation of TP53 and Alteration of p14arf Expression in EGFR- and KRAS-Mutated Lung Adenocarcinomas
Keywords: EGFR; KRAS; Lung adenocarcinoma; p53; p14arf
Prognostic Value of Plasma Soluble Corin in Patients With Acute Myocardial Infarction
Keywords: major adverse cardiac events; natriuretic peptides; prognosis; risk factors; AMI; acute myocardial infarction; ANP; atrial natriuretic peptide; BNP; B-type natriuretic peptide; CABG; coronary artery bypass grafting; eGFR; estimated glomerular filtration r
Incidence, Source, Determinants, and Prognostic Impact of Major Bleeding in Outpatients With Stable Coronary Artery Disease
Keywords: antiplatelet agent; coronary artery disease; major bleeding; oral anticoagulant; outcome; vitamin K antagonist; APT; antiplatelet therapy; BARC; Bleeding Academic Research Consortium; CAD; coronary artery disease; CIs; confidence intervals; eGFR; esti
Pattern of TGFbeta receptor 1 expression differs between kras-mutated keratoacanthomas and squamous cell carcinomas of the skin
Keywords: Skin carcinogenesis; TGFbeta; EGFR; Keratoacanthoma; Squamous cell carcinoma
EGFR mutations and clinical outcomes of chemotherapy for advanced non-small cell lung cancer: A meta-analysis
Keywords: Non-small cell lung cancer; EGFR; Mutation status; Chemotherapy; Response rate; Meta-analysis
Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer
Keywords: CRC; colorectal cancer; APC; adenomatous polyposis coli; KRAS; Kirsten rat sarcoma viral oncogene homolog; TP53; tumor protein p53; IDH1; isocitrate dehydrogenase 1 (NADPÂ +), soluble; IDH2; isocitrate dehydrogenase 2 (NADPÂ +), mitochondrial; DNMT3A; DNA
Chronic kidney disease in type 2 diabetes: Lessons from the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicentre Study
Keywords: Type 2 diabetes; Chronic kidney disease; eGFR; Albuminuria; Diabetic retinopathy; Cardiovascular diseaseCKD, chronic kidney disease; ESRD, end-stage renal disease; CVD, cardiovascular disease; GFR, glomerular filtration rate; RIACE, Renal Insufficiency An
Concurrent Expression of Cyclo-oxygenase-2 and Epidermal Growth Factor Receptor in Canine Malignant Mammary Tumours
Keywords: canine mammary tumours; COX-2; EGFR; therapeutic target
ERCC1 expression correlated with EGFR and clinicopathological variables in patients with non‐small cell lung cancer. An immunocytochemical study on fine‐needle aspiration biopsies samples
Keywords: NSCLC; ERCC1; EGFR; FNABsNSCLC; ERCC1; EGFR; FNABs
Pharmacoperones and the calcium sensing receptor: Exogenous and endogenous regulators
Keywords: ADH; autosomal dominant hypocalcemia; CaSR; calcium sensing receptor; xCT; cystine-glutamate transporter; DHPs; dihydropyridines; EAAT; excitatory amino acid transporter; EGFR; endothelial growth factor receptor; ER; endoplasmic reticulum; ERK1/2; extrace
Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor
Keywords: AUC; area under the curve; Cl; clearance; DAB; 3,3â²-diaminobenzidine; dIF; double immunofluorescence; EGFR; epidermal growth factor receptor; GAG; glycosaminoglycans; GPI; glycosylphosphatidylinositol; FVIII; Factor VIII; FIX; Factor IX; FXa; Factor Xa;
Transcription factor SCL/TAL1 mediates the phosphorylation of MEK/ERK pathway in umbilical cord blood CD34+ stem cells during hematopoietic differentiation
Keywords: UCB; umbilical cord blood; SCL; stem cell leukemia; TAL1; T-cell acute lymphocytic leukemia 1; bHLH; basic helix-loop-helix; EGFR; epidermal growth factor receptor; EPO; erythropoietin; HSCs; hematopoietic stem cells; Transcription factor SCL/TAL1; MEK/ER
SOX4 is associated with poor prognosis in cholangiocarcinoma
Keywords: SOX4; EGFR; Epithelial-mesenchymal transition; Cholangiocarcinoma; Prognosis;
Serum Polyclonal Immunoglobulin Free Light Chain Levels Predict Mortality in People With Chronic Kidney Disease
Keywords: ACR; albumin creatinine ratio; AUC; area under the curve; BP; blood pressure; cFLC; combined free light chain; CKD; chronic kidney disease; CVD; cardiovascular disease; eGFR; estimated glomerular filtration rate; FLC; free light chain; hsCRP; high-sensiti
Quercetin reverses EGF-induced epithelial to mesenchymal transition and invasiveness in prostate cancer (PC-3) cell line via EGFR/PI3K/Akt pathway
Keywords: EMT; epithelial-mesenchymal transition; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; PI3K; phosphatidylinositide 3-kinases.; Epithelial-mesenchymal transition; Epidermal growth facto
Synergistic cytotoxicity of afatinib and cetuximab against EGFR T790M involves Rab11-dependent EGFR recycling
Keywords: EGFR; EGFR-TKI; Cytotoxicity;
Exploring stereoselectivity of 3-indolyl cyclopent[b]indoles: A parallel synthesis and anti-EGFR study on human cancer cells
Keywords: 3-Indolyl cyclopent[b]indole; Cell cycle; Cyclodimerization; EGFR; Lewis acid; Stereoselective;
Use of surface-enhanced Raman scattering to quantify EGFR markers uninhibited by cetuximab antibodies
Keywords: SERS; EGFR; Antibody drug; SERS imaging; Cetuximab
AusSCORE II in predicting 30-day mortality after isolated coronary artery bypass grafting in Australia and New Zealand
Keywords: 23.1.4; AIC; Akaike Information Criteria; ANZSCTS; Australian and New Zealand Society of Cardiac and Thoracic Surgeons; AusSCORE; Australian System for Cardiac Operative Risk Evaluation; CABG; coronary artery bypass grafting; eGFR; glomerular filtration r
Research ArticleEGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition
Keywords: EMT; epithelial-mesenchymal transition; CCA; Cholangiocarcinoma; EGFR; epidermal growth factor receptor; EGF; epidermal growth factor; AJs; adherens junctions; IHC; immunohistochemistry; HPS; hematoxylin phloxine safran; SEM; standard error of the mean; C