دانلود مقالات ISI درباره گیرنده گاما Fc + ترجمه فارسی

بیو تراپی در توسعه غیر بالینی: تقویت رابط بین ایمنی، فارماکوکینتیک، فارماکودینامیک و تولید

Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing

Keywords: گیرنده گاما Fc; Biotherapeutics; Gene and cell therapy; Pharmacokinetics; Non-clinical safety; Immunogenicity; Cross-reactive species; ATMP; advanced therapy medicinal products; CAR; chimeric antigen receptor; CD; cluster of differentiation; CMC; chemistry manufacturing

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

کنترل فوگوسوم و بازآفرینی آنتی ژن

The phagosome and redox control of antigen processing

Keywords: گیرنده گاما Fc; APC; antigen presenting cell; CGD; chronic granulomatous disease; DC; dendritic cell; FcγR; Fc gamma receptor; GILT; γ-interferon-inducible lysosomal thiol reductase; GPI; glucose-6-phosphate isomerase; HEL; hen egg lysozyme; IFN-γ; interferon-gamma; I

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Comparability study of Rituximab originator and follow-on biopharmaceutical

Keywords: گیرنده گاما Fc; AA; amino acid; ABC; ammonium bicarbonate; ACN; acetonitrile; ADCC; antibody-dependent cellular cytotoxicity; CD; circular dichroism; CDC; complement-dependent cytotoxicity; CDRs; complementarity determining regions; CH; constant region of heavy chain; CH

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

یک فرضیه جدید برای مکانیسم 'نجات' قلیایی فسفاتاز در پاسخ ایمنی فاز حاد کبدی

A novel hypothesis for an alkaline phosphatase 'rescue' mechanism in the hepatic acute phase immune response

Keywords: گیرنده گاما Fc; ADP; adenosine diphosphate; AE2; anion exchanger 2; Ala; alanine; AMP; adenosine monophosphate; AP; alkaline phosphatase; Arg; arginine; ATP; adenosine triphosphate; ASGP-R; asialoglycoprotein receptor; Asn; asparagine; ASOR; asialoorosomucoid; BDL; bile

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of amino acid substitutions on the biological activity of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori)

Keywords: گیرنده گاما Fc; Monoclonal antibody; Transgenic silkworm; Amino acid substitution; N-glycosylation; Fc-mediated effector function; ADCC; antibody-dependent cellular cytotoxicity; ADCP; antibody-dependent cellular phagocytosis; CBB; Coomassie Brilliant Blue; CDC; compleme

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice

Keywords: گیرنده گاما Fc; Asn; asparagine; Bisection; bisecting GlcNAc; Fc; fragment crystallizable; FcγR; Fc gamma receptor; GlcNAc; N-acetylglucosamine; HEK; human embryonic kidney; hFcγR; human FcγR; hIgG; human IgG; IgG; immunoglobulin G; mFcγR; -mouse FcγR; mIgG; mouse

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

A simple method for measuring immune complex-mediated, Fc gamma receptor dependent antigen-specific activation of primary human T cells

Keywords: گیرنده گاما Fc; IVIg; Intravenous Immunoglobulin; IC; immune complex; TT; tetanus toxoid; FcγR; Fc gamma receptor; APC; antigen presenting cell; PBMC; peripheral blood mononuclear cells; DC; dendritic cell; MOA; mode of action; CTV; CellTrace Violet; IFN-γ; Interferon-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Boosting half-life and effector functions of therapeutic antibodies by Fc-engineering: An interaction-function review

Keywords: گیرنده گاما Fc; Antibody Fc region; Fc-engineering; Fc gamma receptor; Monoclonal antibody; Neonatal Fc receptor; Serum half-life;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Optimizing conventional DMARD therapy for Sjögren's syndrome

Keywords: گیرنده گاما Fc; 6-MP; 6-mercaptopurine; 6-T-GTP; 6-thioguanine triphosphate; ABT; abatacept; Ach; acetylcholine; ALAT; alanine amino transferase; AZA; azathioprine; BAFF; B cell activating factor; Bcl-6; B cell lymphoma 6; bDMARDs; biological disease modifying antirheuma

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Correlation between cell aggregation and antibody production in IgE-producing plasma cells

Keywords: گیرنده گاما Fc; PC; plasma cell; mAb; monoclonal antibody; TNP; 2,4,6-trinitrophenyl; SN; supernatant; AP; alkaline phosphatase; AI; aggregation index; IgE; Plasma cell; Cell aggregation; Antibody production; Fc gamma receptor; Antigen;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A simple enzyme–substrate localized conjugation method to generate immobilized, functional glutathione S-transferase fusion protein columns for affinity enrichment

Keywords: گیرنده گاما Fc; Glutathione S-transferase; 1-Ethyl-3-(dimethylaminopropyl)carbodiimide (EDC); Antibody; Fc gamma receptor; Nonfucosylation; Glutathione SepharoseGST, glutathione S-transferase; GSH, glutathione; FcγRIIIa, Fc gamma receptor IIIa; IgG1, immunoglobulin G1; N

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewThe double-edge role of B cells in mediating antitumor T-cell immunity: Pharmacological strategies for cancer immunotherapy

Keywords: گیرنده گاما Fc; DC; dendritic cell; NK; natural killer cell; BCR; B-cell receptor; TNF; tumor necrosis factor; MHC; major histocompatibility complex; LMP; liver-metastatic pancreatic; FcγR; Fc gamma receptor; TRAMP; the transgenic adenocarcinoma of the mouse prostate mo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Structural consequences of aglycosylated IgG Fc variants evolved for FcγRI binding

Keywords: گیرنده گاما Fc; Fc; fragment crystallizable; IgG; immunoglobulin G; Fab; fragment antigen binding; FcγR; Fc gamma receptor; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; CDC; complement-dependent cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

PerspectiveAntibody modulation: Limiting the efficacy of therapeutic antibodies

Keywords: گیرنده گاما Fc; FcγR; Fc gamma receptor; mAb; monoclonal antibody; Antibodies; Fc gamma receptor; FcγRIIB; Modulation; Shaving; Immunotherapy; CD20; Tumour resistance;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cells

Keywords: گیرنده گاما Fc; APC; antigen-presenting cell; c-IgG; complexed IgG; DC; dendritic cell; FcγR; Fc gamma receptor; HAGG; heat aggregated IgG; IFNγR; interferon gamma receptor; IL-1R; interleukin-1 receptor; PRR; pattern-recognition receptor; SNP; single nucleotide polymo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1

Keywords: گیرنده گاما Fc; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; AP; alkaline phosphatase; CDC; complement-mediated cytotoxicity; CH2; constant domain 2; DNP; 2,4-dinitrophenyl; EDTA; ethylenediaminetetraacetic aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Impact of Detachment Methods on M2 Macrophage Phenotype and Function

Keywords: گیرنده گاما Fc; MDM; monocyte differentiated macrophage; IFNγ; interferon gamma; LPS; lipopolysaccharide; MHC; major histocompatibility complex; PBMC; Peripheral blood mononuclear cells; M-CSF; macrophage colony-stimulating factor; 7-AAD; 7-amino-actinomycin D; FcγR; F

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

FCGR2A rs1801274 polymorphism is associated with risk of childhood-onset idiopathic (immune) thrombocytopenic purpura: Evidence from a meta-analysis

Keywords: گیرنده گاما Fc; Idiopathic Thrombocytopenic Purpura; Fc gamma receptor; Polymorphism; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Association of serum IgG N-glycome and transforming growth factor-β1 with hepatitis B virus e antigen seroconversion during entecavir therapy

Keywords: گیرنده گاما Fc; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CHB; chronic hepatitis B; CID; collision-induced dissociation; Fc; crystallizable fragment; FcγR; Fc gamma receptor; G0; galactose-deficient; G1; partially galactosylated; G2; fully galactos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A novel FcγRIIa Q27W gene variant is associated with common variable immune deficiency through defective FcγRIIa downstream signaling

Keywords: گیرنده گاما Fc; FcγR; Fc gamma receptor; CVID; common variable immunodeficiency; ITAM; immunoreceptor tyrosine-based activation motif; BCR; B cell receptor; DC; dendritic cells; MAPK; mitogen-activated protein kinase; PBMC; peripheral blood mononuclear cells; ADCC; anti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations

Keywords: گیرنده گاما Fc; ADCC; antibody-dependent cellular cytotoxicity; ADCP; antibody-dependent cellular phagocytosis; BSA; bovine serum albumin; CDC; complement dependent cytotoxicity; D-PBS; Dulbecco's phosphate-buffered saline; ECD; extracellular domain; FACS; fluorescence

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Imaging and measuring the biophysical properties of Fc gamma receptors on single macrophages using atomic force microscopy

Keywords: گیرنده گاما Fc; Atomic force microscopy; Immunotherapy; Antibody; Macrophage; Fc gamma receptor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Chemically dimerized intravenous immunoglobulin has potent ameliorating activity in a mouse immune thrombocytopenic purpura model

Keywords: گیرنده گاما Fc; Intravenous immunoglobulin; Immune thrombocytopenic purpura; Fc gamma receptor; Chemical dimerization; Platelet

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of zinc on human IgG1 and its FcγR interactions

Keywords: گیرنده گاما Fc; CH2 domain; CH3 domain; Fc fragment; Fc gamma receptor; Histidine; Zinc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Cellular immunity and immunopathology in autoimmune Addison's disease

Keywords: گیرنده گاما Fc; 17OH; steroid cytochrome P450 17-alpha-hydroxylase; 21OH; steroid cytochrome P450 21-hydroxylase; AAD; autoimmune Addison's disease; ACA; adrenal cortex autoantibodies; ADCC; antibody dependent cellular cytotoxicity; AIRE; autoimmune regulator; APC; antig

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Development of an antibody-dependent enhancement assay for dengue virus using stable BHK-21 cell lines expressing FcγRIIA

Keywords: گیرنده گاما Fc; Dengue virus; Antibody-dependent enhancement (ADE); Fc gamma receptor; FcγRIIA (CD32a); Stable expression; DF/DHF/DSS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleExperimentally induced liver metastases from colorectal cancer can be prevented by mononuclear phagocyte-mediated monoclonal antibody therapy

Keywords: گیرنده گاما Fc; ADCC; antibody dependent cellular cytotoxicity; ADPh; antibody dependent phagocytosis; CRC; colorectal cancer; FcγR; Fc gamma receptor; FCS; fetal calf serum; Ig; immunoglobulin; i.p.; intraperitoneal; KC; Kupffer cell; mAb; monoclonal antibody; NK; natu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcγRIIa) mediated signaling

Keywords: گیرنده گاما Fc; ADCC; antibody dependent cellular cytotoxicity; FcγR; Fc gamma receptor; GM-CSF; granulocyte macrophage colony-stimulating factor; IFN-γ; interferon gamma; ITAM; immune receptor tyrosine-based activating motif; ITIM; immune receptor tyrosine-based inhib

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Altered balance of inhibitory and active Fc gamma receptors in murine autoimmune glomerulonephritis

Keywords: گیرنده گاما Fc; autoimmunity; Fc gamma receptor; glomerulonephritis; kidney; MRL mice

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Fc receptor-mediated, antibody-dependent enhancement of bacteriophage lambda-mediated gene transfer in mammalian cells

Keywords: گیرنده گاما Fc; Bacteriophage lambda; Antibody-dependent enhancement; Fc gamma receptor; Gene transfer; Virus vector; Endocytosis; CD64; FcγRI; Microtubule; Actin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Association of Fc gamma receptor IIIB polymorphism with renal-allogrft in Chinese

Keywords: گیرنده گاما Fc; Fc gamma receptor; Polymorphism; Acute rejection; Renal allograft

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Human macrophages simultaneously express membrane-C1q and Fc-receptors for IgG

Keywords: گیرنده گاما Fc; FcγR; Fc gamma receptor; Membrane-C1q; MC1q; MΦ; macrophage; sMFI; specific mean fluorescence intensity; PBS; phosphate buffered saline; C1q; Fc-receptors; Monocyte/macrophage; Phagocytosis; Complement; Differentiation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides

Keywords: گیرنده گاما Fc; ADCC; antibody-dependent cellular cytotoxicity; CDC; complement-dependent cytotoxicity; FcγR; Fc gamma receptor; CHO; Chinese hamster ovary; ELISA; Enzyme-linked immunosorbent assay; Antibody oligosaccharide; Antibody-dependent cellular cytotoxicity; IgG

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه