دانلود مقالات ISI درباره Fgf21 + ترجمه فارسی

Insights into the role of hepatocyte PPARα activity in response to fasting

Keywords: Nuclear receptor; PPARα; Fasting; NAFLD; NASH; Steatosis; FGF21; Ketone bodies; Lipolysis; Transcriptome;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis

Keywords: PTP1B; Steatosis; Steatohepatitis; Inflammation; Oval cells; mRNA; messenger RNA; Fgf21; fibroblast growth factor 21; Cd36; fatty acid translocase; IL1β; Interleukin 1β; IL6; Interleukin 6; Ccl2; chemokine (C-C motif) ligand 2; IL4; Interleukin 4; IL1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

FGF21 protects human umbilical vein endothelial cells against high glucose-induced apoptosis via PI3K/Akt/Fox3a signaling pathway

Keywords: FGF21; eNOS; Oxidative stress; Apoptosis; FoxO3a; Akt;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Homeostatic sensing of dietary protein restriction: A case for FGF21

Keywords: Macronutrient; FGF21; Dietary protein; Nutrition;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Fibroblast growth factor 21 ameliorates vascular calcification by inhibiting osteogenic transition in vitamin D3 plus nicotine-treated rats

Keywords: Fibroblast growth factor 21; Vascular calcification; Vascular smooth muscle cells; Osteogenic transition; FGF21; fibroblast growth factor 21; VDN; vitamin D3 plus nicotine; VC; vascular calcification; FGFR1; fibroblast growth factor receptor 1; ALP; alkal

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Nobiletin induces brown adipocyte-like phenotype and ameliorates stress in 3T3-L1 adipocytes

Keywords: 3T3-L1 adipocytes; Anti-obesity; Stress in adipocytes; Fat browning; Nobiletin; ACO; Peroxisomal acyl-coenzyme A oxidase; AMPK; AMP-activated protein kinase; ATG; autophagy protein; ACC; acetyl-CoA carboxylase; BAT; brown adipose tissue; Cidea; gene encod

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice

Keywords: ALT; alanine transaminase; AST; aspartate transaminase; Atgl; adipose triglyceride lipase; AU; arbitrary unit; AUC; area under the curve; BSA; bovine serum albumin; CHOP; C/EBP homologous protein; Cpt2; carnitine palmitoyltransferase 2; DHE; dihydroethidi

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity

Keywords: FGF19; FGF21; KLB; FGFR isoforms; FGF antagonism; Structure-activity-relationship; Alanine-scan;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Loss of DJ-1 promotes browning of white adipose tissue in diet-induced obese mice

Keywords: ACC; acyl-CoA carboxylase; Actb; beta-actin encoding gene; AMPK; AMP-activated protein kinase; ATG; autophagy-related protein; ATGL; adipose triglyceride lipase; ATP5B; ATP synthase subunit beta; β3-AR; beta 3 adrenergic receptor; C/EBPα; CCAAT/enhancer

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Noninvasive Tests Do Not Accurately Differentiate Nonalcoholic Steatohepatitis From Simple Steatosis: A Systematic Review and Meta-analysis

Keywords: ALT; Diagnostic Accuracy; NAFLD Severity; Sensitivity and Specificity; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CK18; cytokeratin 18; FGF21; fibroblast growth factor 21; Fuc-Hpt; fucosylated haptoglobin; G

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

Keywords: Nrf2; type 2 diabetes; natural products; hyperglycemia; cellular stress; insulin sensitivity; β-cell function; vascular complications; AGE; advanced glycation end products; AhR; arylhydrocarbon receptor; AMPK; AMP-activated kinase; ARE; antioxidant respo

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

Research articleα1-Adrenergic receptor downregulates hepatic FGF21 production and circulating FGF21 levels in mice

Keywords: FGF21; Adrenergic receptor; Phentolamine; Prazosin; Glucose tolerance;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

FGF21 deficiency is associated with childhood obesity, insulin resistance and hypoadiponectinaemia: The BCAMS Study

Keywords: Adipokines; Children; Fibroblast growth factor 21; Insulin resistance; Obesity; Metabolic syndrome; FGF21; Fibroblast growth factor 21; IR; Insulin resistance; T2D; Type 2 diabetes; CVD; Cardiovascular disease; MetS; Metabolic syndrome; BMI; Body Mass

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates

Keywords: FGF21; Diet; Carbohydrates; Lipolysis; Liver; ATGL; adipose triglyceride lipase; AMPK; AMP-activated kinase; BCA; bicinchoninic acid; BM; body mass; BMI; body mass index; CHO; carbohydrate-rich diet; ChREBP; carbohydrate-responsive element binding protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism

Keywords: FGF21; ChREBP; Fructose; Lipogenesis; NAFLD;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients

Keywords: AST; aspartate transaminase; ALT; alanine transaminase; BMD; bone mineral density; BMC; bone mineral content; CTX-1; C-telopeptide of type-I collagen; DXA; dual-energy X-ray Absorptiometry; ELISA; enzyme-linked immunosorbent assay; FGF21; fibroblast growt

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

FGF19 and FGF21 serum concentrations in human obesity and type 2 diabetes behave differently after diet- or surgically-induced weight loss

Keywords: Weight loss; Bariatric surgery; Diet; FGF19; FGF21; Obesity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Up-regulation of selenoprotein P and HIP/PAP mRNAs in hepatocytes by intermittent hypoxia via down-regulation of miR-203

Keywords: AHSG; α2 HS-glycoprotein; ANGPTL6; angiopoietin-related growth factor; DROSHA; ribonuclease type III; DICER; endoribonuclease Dicer; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; FGF21; fibroblast growth factor 21; HIP/PAP; hepatocarci

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacological efficacy of FGF21 analogue, liraglutide and insulin glargine in treatment of type 2 diabetes

Keywords: FGF21; Liraglutide; Insulin glargine; Hypoglycemic effect; Type 2 diabetes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Fatty liver and FGF21 physiology

Keywords: Non-alcoholic fatty liver disease; FGF21; Obesity; Metabolic syndrome; Insulin resistance;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Brief CommunicationFGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue

Keywords: FGF21; Resistance; Betaklotho; Obesity; Adipose;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleRepletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution

Keywords: BCAA; Dietary protein; FGF21; mTORC1; Diabetes; PD; protein dilution; AA; amino acid; BCAA; branched chain amino acid; AAD; amino acid diluted; mTORC1; mammalian target of rapamycin complex 1; ISR; integrated stress response; HF; high fat; NZB; New Zealan

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

FGF21 exerts comparable pharmacological efficacy with Adalimumab in ameliorating collagen-induced rheumatoid arthritis by regulating systematic inflammatory response

Keywords: FGF21; Adalimumab; Rheumatoid arthritis; Pro-inflammation cytokines; Anti-inflammation cytokines;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

d-Psicose, a sugar substitute, suppresses body fat deposition by altering networks of inflammatory response and lipid metabolism in C57BL/6J-ob/ob mice

Keywords: Abcd2; ATP-binding cassette, sub-family D, member 2; aP2; adipocyte protein 2; C/EBP-α; CCAAT/enhancer-binding protein-alpha; CPT-1; carnitine palmitoyltransferase-1; FAS; fatty acid synthase; FC; fold change; Fgf21; fibroblast growth factor 21; Fos; FBJ

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Negative correlation between cerebrospinal fluid FGF21 levels and BDI scores in male Chinese subjects

Keywords: FGF21; BDI; SAS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction

Keywords: APAP; acetaminophen; bp; base pair; ChIP; chromatin immunoprecipitation; Cyp; cytochrome p450 enzyme; DEX; dexamethasone; Fgf21; fibroblast growth factor 21; GR; glucocorticoid receptor; GRE; glucocorticoid receptor response element; GSH; Glutathione; i.p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice

Keywords: ALT; Alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; ATMs; adipose tissue macrophages; BAT; brown adipose tissue; CT; computed tomographic; DIO; high-fat-diet-induced obese; EGP; endogenous glucose production

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes

Keywords: FGF21; Therapeutic antibody; Agonist antibody; Thermogenesis; Brown adipose tissue; AUC; area under the curve; BAT; brown adipose tissue; ECD; extracellular domain; EE; energy expenditure; eWAT; epididymal white adipose tissue; FDG; fluorodeoxyglucose; FG

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo

Keywords: ABA; abscisic acid; ATMSC; adipose tissue mesenchymal stem cells; BAT; brown adipose tissue; CIDE-A; cell death-inducing DNA fragmentation factor; FAS; fatty acid synthase; GAPDH; glyceraldeyde-3-phosphate dehydrogenase; LPL; lipoprotein lipase; PCG-1α;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

FGF21 regulates melanogenesis in alpaca melanocytes via ERK1/2-mediated MITF downregulation

Keywords: FGF21; Melanogenesis; MITF; ERK; FGF21-siRNA; Melanocytes;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Relationship between FGF21 and UCP1 levels under time-restricted feeding and high-fat diet

Keywords: BAT; brown adipose tissue; FGF21; fibroblast growth factor 21; HFD; high-fat diet; KD; ketogenic diet; LFD; low-fat diet; RF; restricted feeding; SCN; suprachiasmatic nucleus; UCP1; uncoupling protein 1; WAT; white adipose tissue.; FGF21; UCP1; Adipose ti

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders

Keywords: Adipose tissue; Brown fat; Nrg4; Adipokine; NAFLD; Diabetes; BAT; Brown adipose tissue; WAT; White adipose tissue; eWAT; epididymal WAT; Nrg4; Neuregulin 4; HFD; High-fat diet; TAG; Triglyceride; WT; Wild type; Tg; Transgenic; KO; Knockout; TNFα; Tumor n

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Targeted mitochondrial uncoupling beyond UCP1 - The fine line between death and metabolic health

Keywords: Energy metabolism; Longevity; Mitochondria; Obesity; Protonophore; Uncoupling protein 1; AMPK; AMP-activated protein kinase; aP2; adipocyte protein 2; ATP; adenosine triphosphate; BAT; brown adipose tissue; CRMP; controlled-released mitochondrial protonop

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis

Keywords: CYP2A6; Cytochrome P450 2A6; CYP2E1; Cytochrome P450 2E1; Cyp2e1−/− mice; Cyp2e1 knockout mice; CYP2A5; Cytochrome P450 2A5; Cyp2a5−/− mice; Cyp2a5 knockout mice; NRF2; nuclear factor-erythroid 2-related factor 2; Nrf2−/− mice; Nrf2 knockout m

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Honokiol exerts dual effects on browning and apoptosis of adipocytes

Keywords: ACO; peroxisomal acylcoenzyme A oxidase; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; BAX; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; Cidea; gene encoding cell death-inducing DFFA-like effector a; Cited1; gene encoding Cbp/p30

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Immunoaffinity capture coupled with capillary electrophoresis - mass spectrometry to study therapeutic protein stability in vivo

Keywords: Immunoaffinity capture; Capillary electrophoresis-mass spectrometry; FGF21; Biotransformation; Intact mass analysis; invivo;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Rush to the fire: FGF21 extinguishes metabolic stress, metaflammation and tissue damage

Keywords: CCK; cholecystokinin; HOMA-IR; homeostatic model assessment of insulin resistance; HS; heparan sulfate; KLB; Klotho beta; LPO; lipid peroxide; MCD; methionine- and choline-deficient; MIST1; muscle, intestine and stomach expression 1; NAFLD; non-alcoholic

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity

Keywords: AMPK; Cell non-autonomous; FGF21; Healthspan; Klotho; Lifespan; PERK;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury

Keywords: Binge ethanol consumption; FGF21; Chronic ethanol consumption; Alcoholic liver disease; ACSS2; acyl-coenzyme a synthetase short-chain family member 2; ADH 1 and 2; alcohol dehydrogenase 1 and 2; ALDH1α1; aldehyde dehydrogenase 1 alpha 1; ALD; alcoholic l

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity

Keywords: ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; CCK8; Cell Counting Kit-8; DAB; 3,3′-diaminobenzidine; DAPI; 4′, 6-diamidino-2-phenylindole; DCFH-DA; 2′,7′-Dichlorofluorescein diacetate; DHE; dihydroethidium; D

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacologic stimulation of central GLP-1 receptors has opposite effects on the alterations of plasma FGF21 levels induced by feeding and fasting

Keywords: GLP-1receptor; Liraglutide; FGF21; Body weight; Food intake;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of an artificial peptide agonist to the fibroblast growth factor receptor 1c/βKlotho complex from random peptide T7 phage display

Keywords: Peptide; Agonist; FGFR; βKlotho; FGF21; Phage display; FGFR; fibroblast growth factor receptor; KLB; βKlotho; FGF21; fibroblast growth factor 21; PEG; polyethyleneglycol; Egr-1; early growth response protein-1; RTK; receptor tyrosine kinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Exenatide treatment decreases fasting fibroblast growth factor 21 levels in patients with newly diagnosed type 2 diabetes mellitus

Keywords: FGF21; fibroblast growth factor 21; T2DM; type 2 diabetes mellitus; HOMA-IR; homoeostasis model assessment for insulin resistance; HOMA-B; homoeostasis model assessment for β-cell function; FGFR; fibroblast growth factor receptor; BMI; body mass index; T

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice

Keywords: DEC1; FGF21; Aging; Liver; Hepatic homeostasis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1

Keywords: NS5ATP6; FGF21; miR-577; SIRT1; SREBP1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Low-protein diet induces, whereas high-protein diet reduces hepatic FGF21 production in mice, but glucose and not amino acids up-regulate FGF21 in cultured hepatocytes

Keywords: ACC; acetyl-CoA carboxylase; AEE; energy cost of activity; BAT; brown adipose tissue; FAS; fatty acid synthase; FGF21; fibroblast growth factor 21; CPT1a; carnitine palmitoyltransferase 1a; Gox; glucose oxidation; HPLC; high-protein low-carbohydrate diet;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Fibroblast growth factor 21 (FGF21) inhibits macrophage-mediated inflammation by activating Nrf2 and suppressing the NF-κB signaling pathway

Keywords: RA; rheumatoid arthritis; FGF21; fibroblast growth factor 21; CIA; collagen-induced arthritis; IL-1β; interleukin-1β; TNF-α; tumor necrosis factor; IL-6; interleukin-6; IL-17; interleukin-17; IL-10; interleukin-10; IFN-γ; interferon-γ; ROS; reactive

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Fibroblast growth factor 21, fibroblast growth factor receptor 1, and β-Klotho expression in bovine growth hormone transgenic and growth hormone receptor knockout mice

Keywords: Fibroblast growth factor 21; FGF21; Fibroblast growth factor receptor 1; FGFR1; β-klotho; KLB; bGH mice; GHR −/− mice

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in Sprague–Dawley rats fed prenatal low protein and postnatal high-fat diets

Keywords: Beige adipocyte; FGF21; G9a; Mitochondrial respiration; Prenatal low-protein diet; Postnatal high-fat diet; Subcutaneous adipose tissue

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Vitamin A deficiency suppresses high fructose-induced triglyceride synthesis and elevates resolvin D1 levels

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HFSC; high fructose corn syrup; ALT; alanine aminotransferase; AST; aspartate aminotransferase; RBP4; retinol binding protein 4; FGF21; fibroblast growth factor 21; CRP; C-reac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه