Keywords: HPG; hypothalamic-pituitary-gonadal; GnRH; gonadotropin-releasing hormone; FSH; follicle-stimulating hormone; LH; luteinizing hormone; CNS; central nervous system; HH; hypogonadotropic hypogonadism; PSA-NCAM; polysialic acid form of neural adhesion molecu
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Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
Keywords: Cilia; Ciliopathy; Fuz; Fgf8; Neural crest; Craniofacial; Skull; Calvaria; Coronal suture; Greig cephalopolysyndactyly; Morphogenesis; Craniosynostosis; Wnt1; Mesp1; Mouse;
Keywords: 2210010C04Rik; RIKEN cDNA 2210010C04 gene; 5330417C22Rik; RIKEN cDNA 5330417C22 gene; A1AT; alpha1-antitrypsin; Ago1; argonaute RISC catalytic component 1; Amy2a5; amylase 2a5; Amy2b; amylase, alpha 2B; AP1/JUN; jun proto-oncogene; Bmp; bone morphogenetic
Keywords: AA; ascorbic acid; ALS; amyotrophic lateral sclerosis; BDNF; brain derived neurotropic factor; BMP; bone morphogenetic protein; DNMT; DNA methyltransferase; EB; embryoid body; EBNA1; Epstein-Barr nuclear antigen-1; ERK; extracellular signal-regulated ki
Foxi1 promotes late-stage pharyngeal pouch morphogenesis through ectodermal Wnt4a activation
Keywords: Foxi1; Wnt4; Fgf8; Epithelial morphogenesis; Pharyngeal pouches; Zebrafish;
HDAC8 regulates neural differentiation through embryoid body formation in P19â¯cells
Keywords: Cell cycle; CRISPR-Cas9; HDAC8; HDAC8-Selective inhibitor; NCC-149; Neurodevelopment; CdLS; Cornelia de Lange syndrome; EB; embryoid body; ES cells; embryonic stem cells; FGF8; fibroblast growth factor 8; HDAC; histone deacetylase; HDAC8i; HDAC8-selective
Targeted sequencing identifies novel GATA6 variants in a large cohort of patients with conotruncal heart defects
Keywords: CTDs; Conotruncal heart defects; CHDs; Congenital heart defects; TOF; Tetralogy of Fallot; TGA; Transposition of the great arteries; DORV; Double outlet right ventricle; PA/VSD; Pulmonary atresia with ventricular septal defect; PTA; Persistent truncus art
Extractive from Hypericum ascyron L promotes serotonergic neuronal differentiation in vitro
Keywords: Cell differentiation; Chemical modification; Depression; Chinese medicine; Neural differentiation; Serotonergic neuron; ESCs; embryonic stem cells; 5-HT; 5-hydroxytryptamine; MPLC; medium pressure liquid chromatography; HPLC; high-performance liquid chrom
TGF-β Signaling Regulates Development of Midbrain Dopaminergic and Hindbrain Serotonergic Neuron Subgroups
Keywords: 5-HT; 5-hydroxytryptamine; Aldh1a1; aldehyde dehydrogenase 1 family member A1; Cck; cholecystokinin; cKO; conditional knockout; DIV; day in vitro; DR; dorsal raphe; MR; median raphe; PMR; paramedian raphe; RM; raphe magnus; En1; engrailed 1; ES; embryonic
Proteome response of dental pulp cells to exogenous FGF8
Keywords: FGF8; Dental pulp; Regeneration; ECM remodeling; Angiogenesis; Proteomics;
Dorsal fin development in flounder, Paralichthys olivaceus: Bud formation and its cellular origin
Keywords: Bud formation; Dorsal fin development; Flounder; Cell origin; Median fin; AEF; apical ectodermal fold; AER; apical ectodermal ridge; Col10a1; collagen type l0 alpha 1; DIG; digoxigenin; FGF8; Fibroblast growth factor 8; Hh; hedgehog; Hox; homeobox gene; M
Nuclear receptor corepressors Ncor1 and Ncor2 (Smrt) are required for retinoic acid-dependent repression of Fgf8 during somitogenesis
Keywords: Caudal progenitors; Somitogenesis; Nuclear receptor corepressor; NCOR; SMRT; Fgf8; Retinoic acid response element; CRISPR/Cas9 gene editing;
Lineage-specific loss of FGF17 within the avian orders Galliformes and Passeriformes
Keywords: BMP; bone morphogenetic protein; Bpp; Bayesian posterior probabilities; cDNA; DNA complementary to RNA; CDS; coding sequence; FGF; fibroblast growth factor; FGFR; fibroblast growth factor receptor; indels; insertions/deletion; LRT; likelihood ratio test;
Negative Fgf8-Bmp2 feed-back is regulated by miR-130 during early cardiac specification
Keywords: Cardiac specification; Electroporation; MiR-130; Bmp2; Fgf8
Role of gabra2, GABAA receptor alpha-2 subunit, in CNS development
Keywords: CNS; central nervous system; fgf8; fibroblast growth factor 8; GABA; γ-aminobutyric acid; GABAA; gamma-aminobutyric acid (GABA) A receptor; gabra2; gamma-aminobutyric acid receptor subunit alpha-2; gad1b; glutamate decarboxylase; hpf; hours post-fertilis
Genetic analysis of the TBX1 gene promoter in indirect inguinal hernia
Keywords: DSVs; DNA sequence variants; FGF8; fibroblast growth factor 8; FGF10; fibroblast growth factor 10; FoxA2; forkhead box factor A2; IIH; indirect inguinal hernia; Pitx2; paired-like homeodomain factor 2; SNPs; single nucleotide polymorphisms; TBX1; T-box tr
Distal expression of sprouty (spry) genes during Xenopus laevis limb development and regeneration
Keywords: Sprouty; Regeneration; Limb bud; fgf8; fgf10; Xenopus
Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity
Keywords: Blood; Endothelium; Pronephros; Intermediate mesoderm; Tbx16; Fgf8;
Regulation of neurogenesis by Fgf8a requires Cdc42 signaling and a novel Cdc42 effector protein
Keywords: Neurogenesis; Fgf8; Cdc42; Cdc42 effector protein; Xenopus;
Midbrain dopaminergic neurons: A review of the molecular circuitry that regulates their development
Keywords: A/P; anterior-posterior; BDNF; brain-derived neurotrophic factor; DA; dopaminergic/dopamine; DAT; dopamine transporter; D/V; dorso-ventral; E; embryonic day; En1/2; Engrailed-1/2; FGF8; fibroblast growth factor 8; Fzd; frizzled; GDNF; glial cell line-de
SP8 regulates signaling centers during craniofacial development
Keywords: Craniofacial development; Neural crest; Anterior neural ridge; SP8; FGF8; FGF17; Cyclopamine; Olfactory pits; Signaling center;
Gli3 is required in Emx1+ progenitors for the development of the corpus callosum
Keywords: Gli3; Fgf8; Slit2; Corpus callosum; Dorsal progenitors
Cytomegalovirus-induced salivary gland pathology: AREG, FGF8, TNF-α, and IL-6 signal dysregulation and neoplasia
Keywords: Cytomegalovirus; CMV-induced pathology; Salivary gland; AREG; FGF8; IL-6; TNF-α
Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules
Keywords: Fgf8; Nasal capsule; Optic capsule; Mouse; Ectoderm; Midface; Craniofacial; Trabecular basal plate; FEZ
Permanent expression of midbrain dopaminergic neurons traits in differentiated amniotic epithelial cells
Keywords: Amniotic epithelial cells; Neuron; Dopamine; FGF8; Sonic hedgehog (Shh);
Teneurin protein family: An emerging role in human tumorigenesis and drug resistance
Keywords: Zic1; zinc finger of the cerebellum-1; MBD-1; methyl-CpG binding domain protein 1; TCAP; teneurin-C-terminus associated peptide; CHOP; CCAAT enhancer-binding protein homologous protein; Emx2; empty spiracles homeobox-2; BRCA1; breast and ovarian cancer su
Paraxial left-sided nodal expression and the start of left–right patterning in the early chick embryo
Keywords: Left–right symmetry breaking; Chick; Gastrulation; Sonic hedgehog; Nodal; fgf8
Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons
Keywords: Cranial neural crest; Epibranchial placode; Postganglionic neurons; Fgf8; Mesoderm; Parasympathetic nervous system
Genetic dissection of midbrain dopamine neuron development in vivo
Keywords: Midbrain; Dopamine neurons; Wnt1; Fgf8; Engrailed; ventral tegmental area
Role of fibroblast growth factor (FGF) signaling in the neuroendocrine control of human reproduction
Keywords: GnRH deficiency; Kallmann syndrome; FGF signaling; FGFR1; FGF8; Oligogenicity
Ectodermal WNT/β-catenin signaling shapes the mouse face
Keywords: Craniofacial; Ectoderm; Wnt/β-catenin; FEZ; FGF8;
Sox2 and Fgf interact with Atoh1 to promote sensory competence throughout the zebrafish inner ear
Keywords: Zebrafish; atoh1a/b; sox2; fgf3; fgf8; Hair cell; Support cell; Heat shock;
Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryo
Keywords: Sprouty; Cranial nerves; Epibranchial placodes; FGF8;
The canonical Wnt/Ã-catenin signaling pathway regulates Fgf signaling for early facial development
Keywords: Wnt/Ã-catenin signaling; Anterior neural ridge (ANR); Facial ectoderm; Foxg1-Cre; Fgf8; Mice;
Directed differentiation of porcine epiblast-derived neural progenitor cells into neurons and glia
Keywords: AA; Ascorbic acid; BDNF; Brain-derived neurotrophic factor; bFGF; Basic fibroblast growth factor; ESC; Embryonic stem cell; FGF8; Fibroblast growth factor 8; GDNF; Glial cell line-derived neurotrophic factor; ICM; Inner cell mass; iPSC; Induced pluripoten
FGF8 signaling is chemotactic for cardiac neural crest cells
Keywords: Cardiac neural crest; FGF8; Heart development; Chemokinesis; Chemotaxis; Migration;
Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression
Keywords: Pattern formation; Dorsoventral; Gastrulation; Zebrafish; Oct4/Pou5f1; vox; BMP; FGF8
Induction of human keratinocytes into enamel-secreting ameloblasts
Keywords: Bioengineered tooth; Human keratinocyte stem cell; Mouse dental mesenchyme; FGF8;
Antagonistic crosstalk of Wnt/β-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation
Keywords: Bone morphogenetic protein (Bmp); Wnt/β-catenin; Fgf8; Digit; Interdigit; Limb
Tbx1 is necessary for palatal elongation and elevation
Keywords: Palate; Tbx1; Fgf8; Tgfb3; Fgf10; Shh; Hyaluronic Acid
Clinical genetics of Kallmann syndrome
Keywords: Syndrome de Kallmann-de Morsier; Syndrome CHARGE; Hypogonadisme hypogonadotrope; Anosmie; KAL1; FGFR1; FGF8; PROKR2; PROK2; CHD7Kallmann syndrome; CHARGE syndrome; Hypogonadotropic hypogonadism; Anosmia; KAL1; FGFR1; FGF8; PROKR2; PROK2; CHD7
Pax2 and Pea3 synergize to activate a novel regulatory enhancer for spalt4 in the developing ear
Keywords: Chick; Sall4; Otic induction; Inner ear; FGF8;
Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum
Keywords: Fgf8; Alternative Splicing; Midbrain; Cerebellum; Organizer; Signaling
Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons
Keywords: in vitro differentiation; ventralization factors; TH; Pitx3; HDAC inhibitor; DA; dopamine; FGF8; fibroblast growth factors; nmNSCs; non mesencephalic neural stem cells; Shh; Sonic Hedgehog; TH; tyrosine hydroxylase; TSA; trichostatin A;
Effect of retinoic acid signaling on Wnt/β-catenin and FGF signaling during body axis extension
Keywords: Retinoic acid signaling; Wnt/β-catenin signaling; FGF signaling; Spry2; Pea3; Axin2; Fgf8; Wnt8a; Wnt3a; Tbx6; Cdx; Axis extension;
Expression analysis of Fgf8a & Fgf8b in early stage of P19 cells during neural differentiation
Keywords: Fgf8; Alternative splicing; P19 embryonic carcinoma cell; Neural differentiation; Retinoic acid; Cellular aggregation;
Balancing segmentation and laterality during vertebrate development
Keywords: Somitogenesis; Left–right asymmetry; Retinoic acid; Fgf8
The role of Fgf8 in telencephalic and diencephalic patterning
Keywords: Cortex; Thalamus; Pattern; Fgf8; Evolution;
Early thyroid development requires a Tbx1–Fgf8 pathway
Keywords: Thyroid development; Tbx1; Fgf8; Mouse