Keywords: ACC1; acetylcoenzyme A carboxylase 1; ASIP; agouti signaling protein; BETA2; transcription factor Beta 2; CYP7a1; cytochrome P450, family 7, subfamily a, polypeptide 1; cFOS; transcription factor C-fos; FASN; fatty acid synthase; FOXA2; forkhead box prote
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Keywords: α-CGRP; alpha-calcitonin gene related peptide; Ang; angiopoietin; AE2; anion exchanger 2; ADP; adenosine diphosphate; ADPKD; autosomal dominant polycystic kidney disease; ATP; adenosine triphosphate; ASBT; sodium-dependent bile acid transporter; AQP; aqu
Keywords: 5-HT; serotonin (5-hydroxytryptamine); A83-01; TGF-β kinase/activin receptor-like kinase inhibitor; ACTB; actin beta/beta-actin; ASCL1; achaete-scute homolog 1 (MASH1); ASOs; anti-sense oligonucleotides; Bcl-xL; b-cell lymphoma-extra large; BDNF; brain d
Keywords: Allantois; Brachyury; FOXa2; Hindgut; MIXl1; OCT-3/4; Primitive streak; Primordial germ cells; Runx1; STELLA;
Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; amyloid-β; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; APOE4; apolipoprotein E4; APP; amyloid precursor protein; ASCL1; achaete-scute family basic helix-loop-helix transcription factor 1; ATP; adenosine trip
Keywords: 2210010C04Rik; RIKEN cDNA 2210010C04 gene; 5330417C22Rik; RIKEN cDNA 5330417C22 gene; A1AT; alpha1-antitrypsin; Ago1; argonaute RISC catalytic component 1; Amy2a5; amylase 2a5; Amy2b; amylase, alpha 2B; AP1/JUN; jun proto-oncogene; Bmp; bone morphogenetic
Keywords: apo; apolipoprotein; HDL; high-density lipoprotein; HNF-1α,4α; hepatocyte nuclear factor-1α,4α; LRH-1; liver receptor homolog-1; Foxa2; forkhead box A2; PAF; platelet activating factor; LXR; liver X receptor; RXR; retinoid X receptor; FXR; farnesoid X
Keywords: TUNEL; terminal deoxynucleotidyl transferase dUTP nick-end labeling; ELISA; enzyme-linked immunosorbent assay; DNA; deoxyribonucleic acid; TNFα; tumor necrosis factor-alpha; Foxa2; forkhead box protein A2; HNF6; hepatocyte nuclear factor 6; C/EBPα; CCAA
Keywords: FOXA1; FOXA2; HNF4A; BIRC5; ENCODE; GWAS
Keywords: ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: Foxa2; forkhead box A2; Hnf4α; hepatocyte nuclear factor 4α; Ncam1; neural cell adhesion molecule 1; PDX-1; pancreatic and duodenal homeobox 1; PPARα; peroxisome proliferator activated receptor alpha; PPARγ; peroxisome proliferator activated receptor
Decreased expression of FOXA2 promotes eutopic endometrial cell proliferation and migration in patients with endometriosis
Keywords: cell apoptosis; cell migration; cell proliferation; endometriosis; FOXA2; progesterone resistance;
microRNA-141-3p fosters the growth, invasion, and tumorigenesis of cervical cancer cells by targeting FOXA2
Keywords: Cervical cancer; FOXA2; Growth; Invasion; miR-141-3p;
Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation
Keywords: Foxa1; Foxa2; T-cell development; TEC; Thymus; Treg;
IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies
Keywords: 2DIR; two-dimensional infra-red spectroscopy; AFM; atomic force microscopy; AGE; advanced glycation end; CD; circular dichroism; CGRP; calcitonin gene-related peptides; DMSO; Dimethyl Sulfoxide; EGCG; epigallocatechin gallate; EPR; electron paramagnetic r
Forkhead box protein A2, a pioneer factor for hepatogenesis, is involved in the expression of hepatic phenotype of alpha-fetoprotein-producing adenocarcinoma
Keywords: AFP-producing adenocarcinoma; Alpha-fetoprotein; FoxA2; Hepatogenesis; Live-enriched nuclear factors;
Regulation of the human lipoprotein lipase gene by the forkhead box transcription factor FOXA2/HNF-3β in hepatic cells
Keywords: Lipoprotein lipase; Promoter; FOXA2; HNF-3β; Transcriptional activation; Insulin; Liver; Triglycerides; Lipoproteins;
Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells
Keywords: Foxa2; Pdx1; β-Cell maturation; β-Cell identity; Trans-differentiation;
Metformin impairs systemic bile acid homeostasis through regulating SIRT1 protein levels
Keywords: Bile acid metabolism; Deacetylate; Foxa2; Metformin; SIRT1;
Physical and functional interactions between nuclear receptor LXRα and the forkhead box transcription factor FOXA2 regulate the response of the human lipoprotein lipase gene to oxysterols in hepatic cells
Keywords: Lipoprotein lipase; Promoter; FOXA2; LXR; Oxysterols; Transcriptional activation; Synergistic interactions; Insulin; Liver;
NAP1L1 regulates NF-κB signaling pathway acting on anti-apoptotic Mcl-1 gene expression
Keywords: NF-κB; nuclear factor-κB; Bcl-2; B cell lymphoma protein 2; Bcl-xl; Bcl-2-related protein long form of Bcl-x; Mcl-1; myeloid cell leukemia 1; Bax; bcl-2-associated X protein; NAPs; nucleosome assembly proteins; NAP1L; NAP1 like protein; ÎÎÎζ; diacyl
Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction
Keywords: Human induced pluripotent stem cells; Hepatocyte; Drug metabolism; ATF5; c/EBPα; PROX1; Human iPS-HLCs; Human induced pluripotent stem cells-derived hepatocyte-like cells; HLCs; Hepatocyte-like cells; ATF5; Activating transcription factor 5; c/EBPα; CCA
Interplay of estrogen receptors and FOXA factors in the liver cancer
Keywords: Estrogen receptor (ER); Sexual dimorphism; FOXA1; FOXA2; Hepatocellular carcinoma (HCC); Liver cancer
Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells
Keywords: Hepatitis B virus; Hepatitis B virus replication; FOXA1; FOXA2; FOXA3; HNF3;
Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis
Keywords: ESC; embryonic stem cell; iPSC; induced pluripotent stem cell; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; FoxA2; forkhead box A2; Sox17; sex determining region Y box 17; Oct-4; octamer-binding transcription factor 4; CDH1; E-cadherin-1; IGFR; i
miR-200 modulates coelomocytes antibacterial activities and LPS priming via targeting Tollip in Apostichopus japonicus
Keywords: miR-200; Toll interacting protein; Antibacterial activity; LPS priming; miR-200; microRNA 200; LPS; lipopolysaccharide; Tollip; Toll interacting protein; TLR; Toll like receptor; SUS; skin ulceration syndrome; qPCR; quantitative PCR; CFU; clonal forming u
Transcription factor FOXA2-centered transcriptional regulation network in non-small cell lung cancer
Keywords: FOXA2; Novel binding proteins; Novel target genes; Transcriptional regulatory network;
Genetic analysis of the TBX1 gene promoter in indirect inguinal hernia
Keywords: DSVs; DNA sequence variants; FGF8; fibroblast growth factor 8; FGF10; fibroblast growth factor 10; FoxA2; forkhead box factor A2; IIH; indirect inguinal hernia; Pitx2; paired-like homeodomain factor 2; SNPs; single nucleotide polymorphisms; TBX1; T-box tr
ABCC8 genetic variants and risk of diabetes mellitus
Keywords: KATP; ATP-sensitive K+; CALPN10; calpain 10; PRKACG; cAMP-dependent protein kinase catalytic subunit G; DM; diabetes mellitus; ENSA; endosulfine alpha; FOXA2; forkhead box A2; GWAS; genome-wide association studies; GDM; gestational diabetes mellitus; HVA;
Association analysis of bovine Foxa2 gene single sequence variant and haplotype combinations with growth traits in Chinese cattle
Keywords: Foxa2; Forkhead box A2; DLK1; Delta-like 1; HNF-3; Hepatocyte nuclear factor 3; PCR-RFLP; Polymerase chain reaction-restriction fragment length polymorphism; PCR-ACRS; PCR-based amplification-created restriction site; SNPs; Single nucleotide polymorph
Novel mechanism of transcriptional repression of the human ATP binding cassette transporter A1 gene in hepatic cells by the winged helix/forkhead box transcription factor A2
Keywords: ABCA1; FOXA2; TATA box; Transcriptional repression
Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells
Keywords: ACO; acyl-CoA oxydase; AMPK; AMP-activated protein kinase; APRT; adenosyl phosphoribosyl transferase); ACC; acetyl-CoA carboxylase); ChREBP; carbohydrate response element binding protein; CYP4A1; cytochrome P450 4A1; FAS; fatty acid synthase; Foxa2; forkh
Arx together with FoxA2, regulates Shh floor plate expression
Keywords: Spinal cord; Neural tube; Floor plate; Development; Shh; Arx; FoxA2; Nkx2.2;
Hepatocyte nuclear factors 1α/4α and forkhead box A2 regulate the solute carrier 2A2 (Slc2a2) gene expression in the liver and kidney of diabetic rats
Keywords: SLC2A2; GLUT2; HNFs; Diabetes; EMSA; Nephropathy; FOXA2
Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing
Keywords: Lung cancer; Non-small-cell lung cancer; Foxa2; Methylation; Transcription factors; Epigenetic; Downregulation; Adenocarcinoma; Mutation; Prognosis
Analysis of gene expression profiles in alveolar epithelial type II-like cells differentiated from human alveolar epithelial progenitor cells
Keywords: ABCA3; ATP-binding cassette, sub-family A (ABC1), member 3; AEPC; alveolar epithelial progenitor cell; ATI; alveolar epithelial type I; ATII; alveolar epithelial type II; CDH1; cadherin 1, type 1; C/EBP; CCAAT/enhancer-binding protein; CEBPD; CCAAT/enhanc
Research ArticleGeneration of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction
Keywords: FOXA2; HNF1α; Hepatocytes; Adenovirus; Drug screening; Drug metabolism; hESCs; hiPSCs;
Loss of Oct4 expression during the development of murine embryoid bodies
Keywords: Oct4; Embryoid body; Induced pluripotent stem cells; Endoderm; Mesoderm; Dab2; Alpha-fetoprotein; HNF4; FoxA2; Brachyury; Cardiac troponin T
Post-translational modification of pregnane x receptor
Keywords: PXR; pregnane x receptor; NR; nuclear receptor; PCN; pregnenalone 16α-carbonitrile; Rif; rifampicin; G6Pase; glucose-6-phosphatase; PEPCK; phosphoenolpyruvate carboxykinase; CYP3A; cytochrome P450 3A; CREs; cyclic AMP response elements; PKA; cyclic AMP-d
Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord
Keywords: Noto; Foxa2; Enhancer; Notochord; ChIP-Seq; Microarray
Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors
Keywords: ALDPC; adult liver-derived progenitor cells; iPS; induced pluripotent stem cells; LETF; liver enriched transcription factors; LD; liver differentiation medium; HBM; hepatocyte basal medium; MM; maintenance medium; ESC; embryonic stem cells; Foxa2; forkhea
Foxa2 regulates the expression of Nato3 in the floor plate by a novel evolutionarily conserved promoter
Keywords: Nato3; Foxa2; bHLH transcription factor; Transcriptional regulation; Floor plate; Spinal cord development; Chick in ovo electroporation;
Transcriptional regulation of the hypocretin/orexin gene by NR6A1
Keywords: NR6A1; nuclear receptor subfamily 6, group A, member 1; OE; orexin response element; POU5f1; POU class 5 homeobox 1; NurRE; nuclear receptor response element; GCNF; germ cell nuclear factor; GFP; green fluorescent protein; Nptx2; neural pentaxin 2; Pdyn;
Foxa2 (HNF-3β) regulates expression of hepatotrophic factor ALR in liver cells
Keywords: ALR, augmenter of liver regeneration; Foxa2, Forkhead box A2; IL-6 RE-BP, IL-6 response element binding protein; C/EBPβ, CCAAT/enhancer binding protein β; HNF-4α, hepatocyte nuclear factor 4αAugmenter of liver regeneration; GFER; Liver regeneration; Foxa2
Tissue-specific Forkhead protein FOXA2 up-regulates SOX14 gene expression
Keywords: SOX14; Foxa2; SHH; GLI
Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid
Keywords: FOXA2; HNF3b; A9; A10; Splice variant; Induced; Pluripotent; Stem; Embryonic; Neural
Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer
Keywords: GATA4; Forkhead proteins; FoxA2; Endoderm progenitors; Enhancer; Transgenic mouse
Foxh1 and Foxa2 are not required for formation of the midgut and hindgut definitive endoderm
Keywords: Definitive endoderm; Visceral endoderm; Midgut; Hindgut; Gastrulation; Anterior primitive streak; Foxh1; Foxa2; Cpn1; Pyy; Trh; Nepn;
Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon
Keywords: Lmx1a; Foxa2; Dopaminergic neuron; Floor plate cell; Red nucleus; Mesencephalon; Neuronal identity; Cell fate; Mouse;
Organization of the human embryonic ventral mesencephalon
Keywords: Midbrain; Floor plate; Basal plate; LMX1A; FOXA2; NGN2; PITX3; TH; Parkinson’s disease; Red nucleus; ISL1; BRN3A; NURR1; Dopamine neuron