Keywords: Methylmercury; GCLC; GCLM; GSTP1; Neurodevelopment;
مقالات ISI (ترجمه نشده)
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Keywords: AST; aspartate aminotransferase; ALT; alanine aminotransferase; CBS; cystathionine β-synthase; DNMT; DNA methyltransferase; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cysteine ligase modifier subunit; GSH; glutathione; LPO; lipid
Keywords: Arsenite; Mitochondrial superoxide; Nrf2, GSH; Mitochondrial permeability transition; Apoptosis; AA; l-ascorbic acid; BSO; DL-buthionine-[S,R]-sulfoximine; CsA; cyclosporin A; DHR; dihydrorhodamine 123; DTNB; dithiobis-(2-nitrobenzoic acid); EB; extracell
Keywords: ACR; albumincreatinine ratio; ALT; alanine aminotransferase; AST; aspartic transaminase; BUN; blood urea nitrogen; BW; body weight; CAT; catalase; CK; creatine kinase; Col1α1; collagen1α1; CREA; creatinine; GCLC; glutamate-cysteine ligase catalytic subu
Keywords: nPM / PM0.2; Nano-Scale Particulate Matter / Particulate Matter <â¯0.2â¯Âµm diameter; PM2.5; Particulate Matter <â¯2.5â¯Âµm diameter; Nrf2; Nuclear factor (erythroid-derived 2)-like 2; Bach1; BTB Domain And CNC Homolog 1; c-Myc; MYC proto-oncogene; TR
Keywords: Propolis; Fibroblast; Wound healing; Antioxidant activity; EECP; Ethanol extract of Chinese propolis; HPLC; High performance liquid chromatography; H2O2; Hydrogen peroxide; HO-1; Heme oxygenase-1; GCLC; Glutathione-cysteine ligase catalytic subunits; GCLM
Comparison of chemical structures and cytoprotection abilities between direct and indirect antioxidants
Keywords: AAPH; 2,2â²-azobis (2-amidinopropane) dihydrochloride; ARE; antioxidant responsive element; CAT; catalase; DHMBA; 3,5-dihydroxy-4-methoxybenzyl alcohol; DPPH; 2,2-diphenyl-1-picryl-hydrazyl; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosphate dehy
Keywords: 2OAA; 2-hydroxyarachidonic acid; 4-HNE; 4-hydroxynonenal; AA; arachidonic acid; C-Pu; caudate-putamen; CCA; common carotid artery; cPLA2; cytosolic phospholipase A2; COX; cyclooxygenase; DHA; docosahexaenoic acid; ECA; external carotid artery; FFA; free f
Keywords: DTC; dithiocarbamates; EGCG; (-)-epigallocatechin-3-gallate; DSF; disulfiram; DEDTC; diethyldithiocarbamate; PDTC; pyrrolidine dithiocarbamate; SOD; superoxide dismutase; MT; metallothionein; ROS; reactive oxygen species; γH2AX; histone H2AX; ALT; alanin
Keywords: Sirt1; Sirtuin 1; DMN; dimethylnitrosamine; HO-1; Heme oxygenase -1; GST; glutathione-S-transferase; GCLC; glutathione cysteine ligase catalytic subunit; GCLM; glutathione cysteine ligase modifier subunit; Nrf2; NF-E2-related factor 2; ALT; alanine aminot
Keywords: HF; high-fat; CO; control; PCOOH; phosphatidylcholine hydroperoxide; Gpx1; glutathione peroxidase 1; Sod1; superoxide dismutase 1; Gpx4; glutathione peroxidase 4; Cat; catalase; Gclm; glutamate-cysteine ligase modifier subunit; PC; phosphatidylcholine; CL
Keywords: AMP; amphetamine; AMPT; alpha-methyl-p-tyrosine; BD; bipolar disorder; BDNF; brain-derived neurotrophic factor; BPM; behavioral pattern monitor; CDP; chlordiazepoxide; CRF; corticotropin release factor; EEG; electroencephalography; GCLM; Glutamate-cystein
Keywords: Antioxidant; Oxidative stress; Redox; Tumor; Cancer therapy; Akt; protein kinase B; AMPK; 5â²-adenosine monophosphate-activated protein kinase; ATM; ataxia telangiectasia-mutated; DR5; death receptor 5; EC; epicatechin; ECG; epicatechin-3-gallate; EGC; e
Keywords: HHcy; hyperhomocysteinemia; ZDF; Zucker diabetic fatty; CβS; cystathionine β-synthase; BHMT; betaine-homocysteine methyltransferase; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; MS; methionine synthase; GSH; glutathione; CDO; cysteine dioxyge
Keywords: AJ; adherens junction; BBB; blood-brain barrier; DMF; dimethyl fumarate; FAE; fumaric acid esters; Gclc; glutamate-cysteine ligase catalytic subunit; Gclm; glutamate-cysteine ligase modifier subunit; HO-1; heme oxygenase-1; Keap-1; kelch-like erythroid
Keywords: ARE; Antioxidant responsive element; Cul3; Cullin 3; DEVD; Asp-Glu-Val-Asp; DOX; Doxorubicin; GCLC; Catalytic subunit of glutamate-cysteine ligase; GCLM; Modified subunit of glutamate-cysteine ligase; GSTA4-4; Glutathione S-transferase alpha 4;
Keywords: Acetaminophen; Peroxiredoxin-6; Gender; Mitochondria; Glutathione; Gclm
Keywords: Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ÎΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla
Keywords: ARE; antioxidant response element; CBP; CREB-binding protein; ChIP; chromatin immunoprecipitation; co-IP; coimmunoprecipitation; GCL; glutamate-cysteine ligase; Gclc; GCL catalytic subunit; Gclm; GCL modifier subunit; GSH; reduced glutathione; GS; GSH s
Keywords: ACC; acetyl-CoA carboxylase; Ahcy; adenosylhomocysteinase; AT; adipose tissue; ATGL; adipose triglyceride lipase; AMPK; AMP-activated protein kinase; Bhmt; betaine-homocysteine S-methyltransferase; CR; caloric restriction; CBS; cystathionine β-synthase;
Keywords: Glutathione; Gclm; Oxidative stress; Angiogenesis; Peripheral artery disease; Free radicals;
Keywords: 4-HNE; 4-hydroxynonenal; 15d-PGJ2; 15-deoxy-â12,14-prostaglandin J2; AP-1; activator protein-1; As3 +; trivalent arsenite; α-SMA; a-smooth muscle actin; ARE; antioxidant response element; ATRA; all-trans retinoic acid; BDL; bile duct ligation; BHMT; b
Keywords: ROS; reactive oxygen species; GSH; reduced glutathione; Gcl; glutamate-cysteine ligase; Gclc; glutamate-cysteine ligase catalytic subunit; Gclm; glutamate-cysteine ligase modifier subunit; Gss; glutathione synthetase; GSSG; glutathione disulfide; PC
Selenium unmasks protective iron armor: A possible defense against cutaneous inflammation and cancer
Keywords: GPX4; Glutathione Peroxidase 4; System XC; Cystine/Glutamate Antiporter-System XC; TNFα; Tumor necrosis factor alpha; VEGF; Vascular endothelial growth factor; S1P; Sphingosine-1 phosphate; IL-22; Interleukin-22; Trx1; Thioredoxin; Txnrd1; Thioredoxin re
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress
Keywords: AMPK; adenosine 5'-monophosphate (AMP)-activated protein kinase; CK; creatine kinase; DAPI; 4',6'-Diamidino-2-phenylindole; DOX; doxorubicin; ECG; electrocardiograms; FOXO3a; Forkhead box O3; FXR; farnesoid X receptor; GCLM; glutamatecysteine ligase mod
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro
Keywords: Nuclear factor erythroid-2-related factor 2 (Nrf2); Acetaminophen (APAP); Acute liver injury; Oxidative stress; Ginsenoside Rg1; ALT; alanine transaminase; ARE; antioxidant element; AST; aspartate transaminase; CAT; catalase; GCL; glutamate-cysteine ligas
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway
Keywords: ALI; acute liver injury; AST; aspartate transaminase; CD14; cluster of differentiation 14; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cysteine ligase modifier subunit; GSH; reduced glutathione; HO-1; hemeoxygenase-1; iNOS; inducibl
Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes
Keywords: Acadm; medium-chain acyl-CoA dehydrogenase; AMPKα; AMP-activated protein kinase, α subunit; AST; aspartate aminotransferase; ALT; alanine aminotransferase; BSO; buthionine sulfoximine; CBS; cystathionine-β-synthetase; CPT1a; carnitine palmitoyltransfer
MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2
Keywords: ARE; antioxidant response element; CK; creatine kinase; DAPI; 4â²,6â²- Diamidino-2-phenylindole; DOX; doxorubicin; ECG; electrocardiograms; FOXO3a; Forkhead box O3; GCLM; glutamate-cysteine ligase modifier subunit; GSH; glutathione; GSH-Px; glutathione
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway
Keywords: ARE; antioxidative response element; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; BRCA1; breast cancer susceptibility protein 1; BRCT; BRCA1 C-terminal; BER; base excision repair; CaMKII; calcium/calmodulin-dependent protein kinase II; CNS;
Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer
Keywords: Andrographolide; Andrographis paniculata; Diterpene lactone; Anticancer; Chemotherapy; Bioactive lactone; ACS; American Chemical Society; AKT; activated protein kinase; Andro; Andrographolide derivative or conjugate; AP-1; activator protein-1; Cdk; Cyclin
Silver nanoparticle fate in mammals: Bridging in vitro and in vivo studies
Keywords: 3MPS; 3-mercapto-1-propanesulfonate; AF4; asymmetrical flow field-flow fractionation; AgNM; silver nanomaterial; AgNP; silver nanoparticle; Ag2S; silver sulfide; BSA; bovine serum albumin; CRM; confocal reflectance microscopy; CSE; cystathionine γ-lyase;
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice
Keywords: AEL; aqueous extract of L. chuanxiong rhizome; ARE; antioxidant response element; COX-2; cyclooxygenase-2; DI; didox; DN; diabetic nephropathy; EEL; ethanol extract of L. chuanxiong rhizome; ELISA; enzyme linked immunosorbent assay; ESRD; end stage renal
Cardioprotective role of azafrin in against myocardial injury in rats via activation of the Nrf2-ARE pathway
Keywords: Myocardial infarction; Ischaemia-reperfusion injury; Nrf2-ARE pathway; Azafrin; Oxidative stress; ARE; antioxidant response element; AST; aspartate aminotransferase; CK-MB; MB isoenzyme of creatine kinase; cTnI; cardiac troponin I; CVD; cardiovascular dis
Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway
Keywords: ARE; antioxidant response element; Bcl-2; B-cell lymphoma 2; CA; caffeic acid; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; gl
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects
Keywords: Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; ARE; antioxidant response element; HO-1; heme oxygenase-1; NQO1; NADP(H): quinine oxidoreductase 1; GSTs; glutathione S-transferases; TXNRD; thioredoxin reducta
The AMPK-PGC-1α signaling axis regulates the astrocyte glutathione system to protect against oxidative and metabolic injury
Keywords: Astrocyte; PGC-1α; AMPK; Glutathione; Retina; ROS; GCLM; AICAR;
Nrf2 inhibits oxaliplatin-induced peripheral neuropathy via protection of mitochondrial function
Keywords: AOPPs; advanced oxidation protein products; CI; cell index; DCFH-DA; 2â²,7â²-Dichlorofluorescin diacetate; DHE; dihydroethidium; DAB; 3,3â²-diaminobenzidine-tetrahydrochloride-dihydrate; DRG; dorsal root ganglion; GCLC; glutamate-cysteine ligase cataly
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)
Keywords: NASH; Nrf2; TBE-31; ACACA; acetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOT7; acetyl-CoA thioesterase 7; ACOX2; acetyl-CoA oxidase 2; ADRP; adipose differentiation-related protein; AP-1; activator protein 1; ApoB; apolipoprotein B; ATF4; activa
Oral administration of γ-glutamylcysteine increases intracellular glutathione levels above homeostasis in a randomised human trial pilot study
Keywords: FACS; Fluorescence activated cell sorting; γ-GC; gamma-glutamylcysteine; GCL; glutamate cysteine ligase holoenzyme; GCLC; catalytic subunit of glutamate cysteine ligase; GCLM; modifier subunit of glutamate cysteine ligase; GR; glutathione reductase; γ-G
Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells
Keywords: ARE; antioxidant response element; DHSB; 2,3-dehydrosilybin; DHSC; 2,3-dehydrosilychristin; DHSD; 2,3-dehydrosilydianin; DMSO; dimethyl sulfoxide; Gapdh; glyceraldehyde-3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; gl
Schisandra sphenanthera extract (Wuzhi Tablet) protects against chronic-binge and acute alcohol-induced liver injury by regulating the NRF2-ARE pathway in mice
Keywords: ALD; alcoholic liver disease; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ARE; antioxidant response element; CYP2E1; cytochrome P450 2E1 enzyme; EtOH; ethanol; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cyst
Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
Keywords: α-SYN; alpha synuclein; β-TrCP; β-transducin repeat containing E3 ubiquitin protein ligase; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ASK1; apo
Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress
Keywords: Kidney; Aging; CYP2E1; Apoptosis; Fibrosis; Oxidative stress; APAP; acetaminophen; ATP5B; ATP synthase subunit Beta; CAT; catalase; Cytochrome P450; CYP; DNPH; dinitrophenylhydrazine; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cyst
Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver
Keywords: ACC; acetyl CoA carboxylase; ApoB; apolipoprotein B; COX-1; cytochrome c oxidase subunit 1; CPT1-l; carnitine palmitoyltrasnferase; FAS; fatty acid synthase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic; GCL
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells
Keywords: ABC; ATP-binding cassette; ABCC; The ABC subfamily C; ABCC1; ATP-binding cassette subfamily C member 1; AHR; aryl hydrocarbon receptor; AKR1C1; aldo-keto reductase family 1 member C1; AREs; antioxidant-responsive elements; B-Raf; B-Raf proto-oncogene, ser
Expression of genes involved in oxidative stress response in colonies of the ascidian Botryllus schlosseri exposed to various environmental conditions
Keywords: Botryllus schlosseri; Oxidative stress; Biomarkers; GSH; GPx; SOD; CAT; catalase; GCL; γ-glutamil-cysteine ligase; GCLM; modulatory subunit of γ-glutamyl-cysteine ligase; CTAB; cetyltrimethyl ammonium bromide; GPx; glutathione peroxidase; GSH; glutathio
Photo-pollution stress in skin: Traces of pollutants (PAH and particulate matter) impair redox homeostasis in keratinocytes exposed to UVA1
Keywords: PAH; polycyclic aromatic hydrocarbons; UFP; ultrafine particles; PM; particulate matter; PME; particulate matter extract; d-UV; daily ultraviolet; BaP; benzo[a]pyrene; IcdP; indeno[1,2,3-cd]pyrene; GSH; reduced glutathione; BSO; buthionine sulfoximine; Ph
Keap1 knockdown in melanocytes induces cell proliferation and survival via HO-1-associated β-catenin signaling
Keywords: CoPP; cobalt (III) protoporphyrin IX chloride; GCLC; gamma-glutamyl-cysteine-ligase catalytic subunit; GCLM; gamma-glutamyl-cysteine ligase modifying subunit; GO; gene ontology; GSK-3β; glycogen synthase kinase 3 beta; HO-1; heme oxygenase-1; KEAP1; kelc