دانلود مقالات ISI درباره Gpcrs + ترجمه فارسی

C-tail mediated modulation of somatostatin receptor type-4 homo- and heterodimerizations and signaling

Keywords: cAMP; cyclic adenosine monophosphate; Co-IP; co-immunoprecipitation; D and A; donor and acceptor; D-PBS; Dulbecco's phosphate buffered saline; ERKs; extracellular signal-regulated kinases; FSK; forskolin; GPCRs; G-protein coupled receptors; hSSTR; human s

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2009 سفارش ترجمه

Dark and photoactivated rhodopsin share common binding modes to transducin

Keywords: Molecular recognition; Protein-protein docking; Computational modeling; GPCRs; G protein;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Cell responses regulated by early reorganization of actin cytoskeleton

Keywords: Actin cytoskeleton; Cell response; TNFα; GPCRs; Ion channel; Membrane-androgen receptorTNFα, tumor necrosis factor-α; GPCRs, G-protein coupled receptors

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Pharmacological profile of somatostatin and cortistatin receptors

Keywords: Somatostatin; Cortistatin; MrgX2; GHS-R1a; GPCRs; Radioligand binding; Second messengers

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Deorphanisation of G protein-coupled receptors: A tool to provide new insights in nervous system pathophysiology and new targets for psycho-active drugs

Keywords: GPCRs; Deorphanisation; Psycho-active drugs; Central nervous system;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Homology modeling of MT1 and MT2 receptors

Keywords: Melatonin; GPCRs; Activation; DockingGPCR, G-protein coupled receptor; TM, transmembrane domain

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2008 سفارش ترجمه

Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a

Keywords: Niacin; GPR109a; GPR109b; GPCRs; Lipolysis; Free fatty acids; Selectfluor; Cutaneous flushing; Pyrazole carboxylic acids; HM74; HM74a; PUMA-G

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: Insights from computational analysis

Keywords: Molecular recognition; Docking; GPCRs; G proteinsGt, transducin; GPCRs, G protein-coupled receptors; Rho, rhodopsin; PSB, protonated Schiff base; MII, Meta II; MI, Meta I; H, helix; AFM, atomic force microscopy; ZD, ZDOCK; PDB, Protein Data Bank; Cα-RMSD,

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Yeast-based screening to identify modulators of G-protein signaling using uncontrolled cell division cycle by overexpression of Stm1

Keywords: GPCRs; Stm1; Mitotic haploidization; Schizosaccharomyces pombe; Yeast-based screening;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

The CCK-2/gastrin splice variant receptor retaining intron 4 transactivates the COX-2 promoter in vitro

Keywords: CCK; cholecystokinin; CCK-2R; cholecystokinin-2/gastrin receptor; CCK-2i4svR; a splice variant of the CCK-2R retaining intron 4; CCK-2R wild type; C/EBPs; CCAAT/enhancer-binding proteins; COX; cyclooxygenase; COX-2; cyclooxygenase-2; G-17; gastrin-17; GPC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

PACAP, VIP and their receptors in the metazoa: Insights about the origin and evolution of the ligand–receptor pair

Keywords: Evolution; GPCRs; Ligand–receptor; Metazoan; PACAP; VIP

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors

Keywords: Melanocortins; Peptide mimetics; GPCRs

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Progestin, estrogen and androgen G-protein coupled receptors in fish gonads

Keywords: Progestin membrane receptors; Estrogen membrane receptors; Androgen membrane receptors; GPCRs; Sperm motility; Fish gonads; Nongenomic steroid actions

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Sustained neurotensin exposure promotes cell surface recruitment of NTS2 receptors

Keywords: Neurotensin; GPCRs; Long-term stimulation; Down-regulation; Intracellular stores; Recycling; Internalization

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Identification of small molecule antagonists of the human mas-related gene-X1 receptor

Keywords: GPCRs; MRG-X1; High-throughput screening; Reporter gene assay; Receptor trafficking; GFP; Azabicyclo-octanes

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Pharmacological characterization and autoradiographic distribution of α2-adrenoceptor antagonist [3H]RX 821002 binding sites in the chicken brain

Keywords: chicken brain; α2-adrenoceptor; RX 821002; membrane homogenate binding; autoradiography; competition; ARC 239; 2-(2-4-(O-methoxyphenyl)-piperazin-1-yl)-ethyl-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione; Bmax; maximal number of binding sites; BRL 44408; 2-(

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Computational prediction of homodimerization of the A3 adenosine receptor

Keywords: GPCRs; Purine receptors; Rhodopsin; Homology modeling; Protein–protein docking

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

SAR studies of 2-arylthiazolidine-4-carboxylic acid amides: A novel class of cytotoxic agents for prostate cancer

Keywords: Prostate cancer; GPCRs; Synthesis; SAR

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Receptor systems: Will mining the receptorome yield novel targets for pharmacotherapy?

Keywords: Receptorome; Drugs of abuse; GPCRs; Drug screening; HTS;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception

Keywords: MRG; mas-related gene; GPCR; G-protein-coupled receptor; GPCRs; Human-specific substitution; Darwinian positive selection; Drug target;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Entamoeba histolytica: Identification of EhGPCR-1, a novel putative G protein-coupled receptor that binds to EhRabB

Keywords: GDI; GDP-dissociation inhibitor; GEF; guanine exchange factor; GPCRs; G protein-coupled receptors; ORF; open reading frame; SD; synthetic dropout medium; TM; transmembranal; Entamoeba histolytica; EhRabB; GPCRs; Phagocytosis; Rab GTPase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators

Keywords: GPCRs; Glutamate; mGlu receptors; Allosteric; Schizophrenia;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Regulation of the amyloid precursor protein ectodomain shedding by the 5-HT4 receptor and Epac

Keywords: ACh; acetylcholine; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease; Aβ; amyloid β-peptide; APP; amyloid precursor protein; sAPPα; soluble form of the amyloid precursor protein; FSK; forskolin; GEF; guanine nucleotide exchange factor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

The GRAFS classification system of G-protein coupled receptors in comparative perspective

Keywords: Evolution; GPCRs; MSH; ACTH; NPY;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Role of MEK-ERK pathway in sphingosylphosphorylcholine-induced cell death in human adipose tissue-derived mesenchymal stem cells

Keywords: MSCs; mesenchymal stem cells; SPC; sphingosylphosphorylcholine; MAPKs; mitogen-activated protein kinases; ERK; extracellular signal-regulated kinase; JNK; c-Jun NH2-terminal protein kinase; GPCRs; G protein-coupled receptors; hATSCs; human adipose tissue-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

The conformation of the cytoplasmic helix 8 of the CB1 cannabinoid receptor using NMR and circular dichroism

Keywords: CD; circular dichroism; CNS; Central nervous system; DPC; Dodecylphosphocholine; SDS; sodium dodecyl sulfate; GPCRs; G-protein coupled receptors; MP-X; mastoparan-X; TM; transmembrane helix; Cannabinoid receptor; CB1; NMR; Helix 8; Circular dichroism; The

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Sphingosylphosphorylcholine generates reactive oxygen species through calcium-, protein kinase Cδ- and phospholipase D-dependent pathways

Keywords: SPC; sphingosylphosphorylcholine; GPCRs; G protein-coupled receptors; PLC; phospholipase C; PIP2; phosphatidylinositol 4, 5-bisphosphate; [Ca2+]i; intracellular Ca2+; PLD; phospholipase D; LPA; lysophosphatidic acid; PKC; protein kinase C; ARF; ADP-ribosy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Human H9 cells proliferation is differently controlled by Vasoactive Intestinal Peptide or Peptide Histidine Methionine: implication of a GTP-insensitive form of VPAC1 receptor

Keywords: PHM; Peptide Histidine Methionine; VIP; Vasoactive Intestinal Peptide; cAMP; cyclic AMP; AC; Adenylate Cyclase; PHI; Peptide Histidine Isoleucine; PACAP; Pituitary Adenylate Cyclase-Activating Peptide; PHV; Peptide Histidine Valine; GPCRs; G protein-coupl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors

Keywords: ADH; Adhesion family; BLAST; basic local alignment search tool; BLAT; blast like alignment tool; CASR; calcium-sensing receptor; CNS; central nervous system; EST; expressed sequence tag; GABA; gamma-aminobutyric acid; GPCRs; G protein-coupled receptors; G

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه