دانلود مقالات ISI درباره Gsk3Β + ترجمه فارسی

Sargaquinoic acid ameliorates hyperpigmentation through cAMP and ERK-mediated downregulation of MITF in α-MSH-stimulated B16F10 cells

Keywords: α-MSH; α-melanocyte stimulating hormone; BISA; bisabolangelone; cAMP; cyclic adenosine monophosphate; CREB; cAMP-responsive element-binding protein; DOPA; 3, 4-dihydroxyphenylalanine; ESS; ethanolic extract of Sargassum serratifolium; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

miR-23c suppresses tumor growth of human hepatocellular carcinoma by attenuating ERBB2IP

Keywords: HCC; hepatocellular carcinoma; TACE; transarterial chemoembolization; miRNA; microRNAs; LIHC; liver hepatocellular carcinoma; ELAVL1; ELAV like RNA binding protein 1; GSK3β; glycogen synthase kinase 3 beta; ECM; extracellular matrix; CRC; colorectal canc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Emerging roles and mechanisms of FOXC2 in cancer

Keywords: FOXC2; Forkhead box protein C2; EMT; epithelial-mesenchymal transition; NSCLC; non-small cell lung cancer; EGFR; epidermal growth factor receptor; siRNA; small (or short) interfering RNA; MAPK; mitogen-activated protein kinase; PI3K; phosphatidylinosito

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p

Keywords: 3-MCPD; 3-chloro-1,2-propanediol; 3′UTR; 3′ un-translated region; AKI; acute kidney injury; BMD10; Benchmark doses; BMDL10; BMD Lower Confidence Limit; BW; body weight; CXCl; chemokine (C-X-C motif) ligand; DE; differentially expressed; DR6; death rec

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

S-oxiracetam ameliorates ischemic stroke induced neuronal apoptosis through up-regulating α7 nAChR and PI3K / Akt / GSK3β signal pathway in rats

Keywords: Ischemic stroke; Apoptosis; S-oxiracetam; α7 nAChR; GSK3β;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Δ9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult

Keywords: 2-AG; 2-arachidonoyl glycerol; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine; A-Taur; N-arachidonoyl taurine; Cdkn1a; cyclin dependent kinase inhibitor 1A; CER; cerebellum specific for this study; cldn5; claudin 5; CTX; cortex specific for this s

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The origin of GSKIP, a multifaceted regulatory factor in the mammalian Wnt pathway

Keywords: Bioinformatics; DUF727; GSKIP; PKA; GSK3β; Wnt pathway;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A

Keywords: AC; adenylyl cyclase; AD; Alzheimer's disease; Akt; protein kinase B; Aβ; beta-amyloid; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin, CRE, cyclic AMP response element; CREB; CRE-binding protein; GABA; γ-aminobutyric acid; GFAF; glial

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Exendin-4 promotes proliferation of adipose-derived stem cells through PI3K/Akt-Wnt signaling pathways

Keywords: Exendin-4; Adipose-derived stem cell; Proliferation; PI3K-Akt; GSK3β; Wnt-β-catenin pathway;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Salvianolic acid B promotes neural differentiation of induced pluripotent stem cells via PI3K/AKT/GSK3β/β-catenin pathway

Keywords: Induced pluripotent stem cells; Salvianolic acid B; Neuronal differentiation; AKT; GSK3β;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity

Keywords: Diabetes; Depression; Liraglutide; ACTH; Long-term potentiation; Neurogenesis; Glucocorticoid receptors; GSK3β;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Two Weeks of Variable Stress Increases Gamma-H2AX Levels in the Mouse Bed Nucleus of the Stria Terminalis

Keywords: BNST; bed nucleus of the stria terminalis; DSBs; double-strand breaks; GSK3β; glycogen synthase kinase 3 β; MAPK; mitogen-activated protein kinase; mPFC; medial prefrontal cortex; PBS; phosphate-buffered saline; γH2AX; Histone H2A-X phosphorylated at s

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Tubulin-dependent secretion of S100A6 and cellular signaling pathways activated by S100A6-integrin β1 interaction

Keywords: BSA; bovine serum albumin; CCCP; carbonyl cyanide chlorophenylhydrazone; DPBS; Dulbecco's Phosphate Buffered Saline; DTT; dithiothreitol; EGFR; epidermal growth factor receptor; FAK; focal adhesion kinase; GSK3β; glycogen synthase kinase-3β; ILK; integr

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Can we increase the speed and efficacy of antidepressant treatments? Part II. Glutamatergic and RNA interference strategies

Keywords: Ketamine; microRNA; Prefrontal cortex; Small interfering RNA; RNA interference; 5-HT; serotonin; 5-HT1A receptor; serotonin 1A receptor; A1; adenosine A1 receptor; AchE; acetylcholinesterase; AGO; argonaute; Akt-mTOR; protein kinase B/Akt- mammalian targe

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Leptin in the nucleus accumbens core disrupts acute cocaine effects: Implications for GSK3β connections

Keywords: Leptin; Cocaine; Nucleus accumbens; GSK3β; Locomotor activity;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer

Keywords: 7-AAD; 7-amino-actinomycin D; ABC; ATP-binding cassette; AEC; 3-amino-9-ethyl carbazole; ATD; acute toxicity determination; Atg5; autophagy protein 5; ATP; adenosine-5′-triphosphate; BCL-2; B-cell lymphoma 2; Bip/GRP78; binding immunoglobulin protein/78

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity

Keywords: Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Methacholine induces extracellular matrix production by human airway smooth muscle cells through β-catenin signaling

Keywords: Methacholine; Collagen I; β-catenin; GSK3β; TGF-β; Human airway smooth muscle cells;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc

Keywords: CaMKII; calmodulin-dependent protein kinase II; CDK; cyclin-dependent kinase; ERK; extracellular signal-regulated kinase; FBXW7; F-box/WD repeat containing protein 7; FN3; fibronectin type III domain; FHA1; forkhead-associated 1 domain; GSK3β; glycogen s

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Hypoglycemic mechanism of a novel proteoglycan, extracted from Ganoderma lucidum, in hepatocytes

Keywords: PTP1B inhibitor; Proteoglycan; Hepatocytes; Ganoderma lucidum; GSK3β;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Blockage of endoplasmic reticulum stress attenuates nilotinib-induced cardiotoxicity by inhibition of the Akt-GSK3β-Nox4 signaling

Keywords: Nilotinib; ER stress; Akt; GSK3β; Nox4; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway

Keywords: BCAP; B-cell adaptor for PI3K; PI3K; phosphatidylinositol 3-Kinase; BMM; bone marrow-derived monocyte/macrophage lineage cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K pathway in prostate cancer: All resistant roads lead to PI3K

Keywords: CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization and function of GSK3β from Litopenaeus vannamei in WSSV infection

Keywords: Litopenaeus vannamei; WSSV; GSK3β; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Raffinose from Costus speciosus attenuates lipid synthesis through modulation of PPARs/SREBP1c and improves insulin sensitivity through PI3K/AKT

Keywords: Anti-diabetes; Anti-adipogenesis; Lipid metabolism; Insulin signaling; ACC; acetyl-CoA carboxylase; ACO; Acyl CoA Oxidase; Comp C; Compound C; CSEW; Costus speciosus ethanolic water extract; DMEM; Dulbecco's Modified Eagle Medium; FAS; fatty acid synthase

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1

Keywords: GSK3β; glycogen synthase kinase 3β; HFD; high-fat diet; HMGA1; high mobility group AT-hook 1; IR; insulin receptor; IRS; insulin receptor substrate; NAFLD; nonalcoholic fatty liver disease; G9a/EHMT2; Hepatic insulin signaling; Insulin receptor; HMGA1;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts

Keywords: ACs; aberrant crypts; ACFs; aberrant crypt foci; AGEs; advanced glycation end products; ALA; alagebrium chloride; AOM; azoxymethane; BW; body weight; ERK; extracellular signal-regulated kinase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GLO; glyoxal

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Mkp-1 protects mice against toxin-induced liver damage by promoting the Nrf2 cytoprotective response

Keywords: ALT; alanine aminotransferase; ARE; antioxidant response element; AST; aspartate transaminase; BHA; butylated hydroxyanisole; CCl4; carbon tetrachloride; β-TrCP; β-transducin repeat-containing protein; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyde-3-p

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway

Keywords: HFD; high fat-diet; STZ; streptozotocin; IRS-1; insulin receptor substrate-1; PI3K; phosphatidylinositol 3-kinase; PEPCK; phosphoenolpyruvate carboxykinase; G6pase; glucose 6-phosphatase; FOXO1; forkhead box O1; GSK3β; glycogen synthase kinase-3β; GS; g

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity

Keywords: Vascular smooth muscle; Vasoproliferative disease; Vascular smooth muscle cell; Phenotype switching; Signalling pathways; AJ; adherens junction; ApoE; apolipoprotein E; BMP; bone morphogenetic protein; CAD; coronary artery diseases; CADASIL; cerebral auto

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Minocycline protects developing brain against ethanol-induced damage

Keywords: Apoptosis; Development; Fetal alcohol syndrome; Inflammation; Microglia; Neurodegeneration; AD; Alzheimer's disease; CNS; central nervous system; FASD; fetal alcohol spectrum disorder; GSK3β; Glycogen synthase kinase 3 beta; Iba-1; ionized calcium bindin

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Cardiac repair by epicardial EMT: Current targets and a potential role for the primary cilium

Keywords: BBS8; Bardet-Biedl syndrome 8; bFGF; basic fibroblast growth factor; BMP; bone morphogenetic protein; BMSCs; bone marrow-derived hematopoietic stem cells; ECM; extracellular matrix; EGF; epidermal growth factor; EMT; epithelial-to-mesenchymal transition;

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2018 سفارش ترجمه

ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK

Keywords: 2-NBDG; 2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl]amino)-2-deoxyglucose; AICAR; 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside; AMPK; AMP-activated protein kinase; AS160; Akt Substrate of 160 kDa; ATF4; Activating Transcription Factor 4; AUC; area un

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

Dual hypopigmentary effects of punicalagin via the ERK and Akt pathways

Keywords: α-MSH; α-melanocyte-stimulating hormone; ERK; extracellular signal-regulated kinase; GSK3β; glycogen synthase kinase3β; MITF; microphthalmia-associated transcription factor; Akt; ERK; Melanogenesis; MITF; Punicalagin; Tyrosinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-181a and its target Smad 7 as potential biomarkers for tracking child acute lymphoblastic leukemia

Keywords: ALL; Acute lymphoblastic leukemia; AML; acute myeloid leukemia; CDKs; cyclin-dependent kinases; CLL; chronic lymphocytic leukemia; ELISA; enzyme linked immunosorbent assay; GSK3β; glycogen synthase kinase 3β; I-Smads; inhibitory Smads; qRT-PCR; quantita

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Cytotoxic activities of Telectadium dongnaiense and its constituents by inhibition of the Wnt/β-catenin signaling pathway

Keywords: Wnt/β-catenin signaling; Cytotoxicity; Colon cancer cells; Asclepiadaceae; Telectadium dongnaiense Pierre ex Costantin; Periplocin; TDB; Telectadium dongnaiense Pierre ex Costantin bark; CK1α; casein kinase 1α; APC; adenomatous polyposis coli; GSK3β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of mitochondrial dynamics by DISC1, a putative risk factor for major mental illness

Keywords: Mitochondrial dynamics; Mitochondrial trafficking; DISC1; NDE1; TRAK1/2; GSK3β; DISC1; Disrupted in Schizophrenia 1; DISC1FP1; DISRUPTED in Schizophrenia 1 Fusion Partner 1; FEZ1; Fasciculation and Elongation Protein Zeta 1; GABAA; Gamma-Aminobutyric Aci

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Dexmedetomidine attenuates propofol-induce neuroapoptosis partly via the activation of the PI3k/Akt/GSK3β pathway in the hippocampus of neonatal rats

Keywords: Propofol; Dexmedetomidine; Apoptosis; AKT; GSK3β;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways

Keywords: AB; (aortic banding); AKT; (protein kinase B),; AMPKα; (AMP­activated protein kinase α),; ANP; (atrial natriuretic peptide),; BW; (body weight),; BNP; (brain natriuretic peptide),; CF; (cardiac fibroblast),; ERK; (extracellular signal-regulated kinase)

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Depsidone and xanthones from Garcinia xanthochymus with hypoglycemic activity and the mechanism of promoting glucose uptake in L6 myotubes

Keywords: GLUT4; glucose transporter type 4; PI3K; phosphatidylinositol-3 kinase; PKB/Akt; serine/threonine kinase protein kinase B; AMPK; AMP-activated protein kinase; DM; diabetes mellitus; T2DM; type 2 diabetes mellitus; DMEM; Dulbecco's modified Eagle's med

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportAntidepressant-like effects of ginsenoside Rg2 in a chronic mild stress model of depression

Keywords: AMPK; AMP-activated protein kinase; BDNF; brain derived neurotrophic factor; CMS; chronic mild stress; CREB; cAMP response element-binding protein; FST; forced swimming test; GSK3β; glycogen synthase kinase-3β; MAOI; monoamine oxidase inhibitors; NARI;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Downregulation of TRB3 protects neurons against apoptosis induced by global cerebral ischemia and reperfusion injury in rats

Keywords: ANOVA; analysis of variance; ATF4; transcription factor 4; Bad; Bcl-2-associated death protein; BCA; bicinchoninic acid assay; CA; cornu ammonis; CHOP; CCAAT/enhancer-binding protein (C/EBP) homologous protein; DAB; diaminobenzidine; DAPI; 4,6,diamidino-2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult

Keywords: 8-OHdG; 8-hydroxygluanine; ARE; antioxidant response element; GSK3β; glycogen synthase kinase 3β; HO-1; hemeoxygenase-1; LDH; lactate dehydrogenase; MDA; malondialdehyde; NQO1; NADPH quinone oxidoreductase 1; Nrf2; nuclear factor erythroid 2-related fac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Protein tyrosine phosphatase SHP-1 modulates osteoblast differentiation through direct association with and dephosphorylation of GSK3β

Keywords: SHP-1; Osteoblast; GSK3β;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

MiR-26a enhances invasive capacity by suppressing GSK3β in human lung cancer cells

Keywords: MiR-26a; Lung cancer; Metastasis; GSK3β; β-catenin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleBruceine D inhibits hepatocellular carcinoma growth by targeting β-catenin/jagged1 pathways

Keywords: BD; Hepatocellular carcinoma; β-catenin; Jagged1; Wnt/Notch crosstalk; Sorafenib; HCC; hepatocellular carcinoma; BD; bruceine D; APC; adenomatous polyposis coli; GSK3β; glycogen synthase kinase-3β; LEF1; lymphoid enhancer binding factor 1; TCF4; T-cell

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Synthetic triterpenoids inhibit GSK3β activity and localization and affect focal adhesions and cell migration

Keywords: CDDO; 2-cyano 3,12-dioxooleana-1,9 (11)-dien-28-oic acid; Im; imidazolide; Me; methyl ester; FAK; focal adhesion kinase; GSK3β; Glycogen Synthase Kinase 3 Beta; APC; adenomatous polyosis coli; DMSO; dimethyl sulfoxide; NaCl; sodium chloride; LiCl; lithiu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Nanoquinacrine caused apoptosis in oral cancer stem cells by disrupting the interaction between GLI1 and β catenin through activation of GSK3β

Keywords: Hedgehog; WNT; CSC; GSK3β; Quinacrine; Oral cancer stem cells;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells

Keywords: Sulforaphane (SFN) (PubChem CID: 5350); Dimethyl Sulfoxide (DMSO) (PubChem CID: 679); Lithium chloride (LiCl) (PubChem CID: 433,294); Lung cancer stem cells; Wnt/β-catenin pathway; miR-19; GSK3β; Sulforaphane;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه