Keywords: فاکتور تبادل گوانین; Immunology; primary immunodeficiency; whole-exome sequencing; hematopoietic stem cell transplantation; common variable immunodeficiency; severe combined immunodeficiency; hyper-IgE syndrome; AIP1; Actin-interacting protein 1; APDS; Activated PI3Kδ syndro
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Keywords: فاکتور تبادل گوانین; AbA; Aureobasidin A; ABC; ATP-binding cassette; AMPK; AMP-activated protein kinase; ATG; Autophagy-related; ATP; Adenosine triphosphate; C1P; Ceramide-1-phosphate; CERS; Ceramide synthase; CK2; Casein kinase II; CLS; Chronological lifespan; CMA; Chaperone
Keywords: فاکتور تبادل گوانین; Dendritic spine; Synaptic plasticity; Neurodegenerative diseases; Psychiatric disorders; Glutamate receptor; Calcium signaling; ADHD; attention deficit hypersensitive disorders; FXS; Fragile X-syndrome; CNS; central nervous system; GABA; gamma amino butyr
Relevance of small GTPase Rac1 pathway in drug and radio-resistance mechanisms: Opportunities in cancer therapeutics
Keywords: فاکتور تبادل گوانین; GEF; Guanine Exchange Factor; GAP; GTPase-activating protein; EGF; epidermal growth factor; PDGF; platelet-derived growth factor; EGFR; epidermal growth factor receptor; Pak; p21-activated kinase; EMT; epithelial to mesenchymal transition; SCC; squamous c
Paving the Rho in cancer metastasis: Rho GTPases and beyond
Keywords: فاکتور تبادل گوانین; ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena
Imaging flow cytometry and GST pulldown assays provide new insights into channel catfish leukocyte immune-type receptor-mediated phagocytic pathways
Keywords: فاکتور تبادل گوانین; Phagocytosis; Immunoregulatory receptors; Intracellular signaling; Actin polymerization machinery; Imaging flow cytometry; Innate immunity; Channel catfish; Leukocyte immune-type receptors; IpLITR; channel catfish leukocyte immune-type receptor; CYT; cyto
Interaction of KRas4b with anionic membranes: A special role for PIP2
Keywords: فاکتور تبادل گوانین; KRas4b; Nanodisc; Cancer signaling; Lipid specificity; PIP2; CD; Catalytic Domain; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DMPS; 1,2-dimyristoyl-sn-glycero-3-phospho-l-serine; GAP; GTPase activating proteins; GDP; Guanosine diphosphate; GEF; Gu
Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex
Keywords: فاکتور تبادل گوانین; Arg1; Arginase 1; DH-PH domain; the diffuse B-cell lymphoma (Dbl) domain and pleckstrin-homology domain; GDP; guanosine diphosphate; GEF; guanine exchange factor; GM130; 130 kDa cis Golgi matrix protein; GTP; guanosine triphosphate; INF-γ; Interferonγ;
DOCK8 deficiency: Insights into pathophysiology, clinical features and management
Keywords: فاکتور تبادل گوانین; Actin; CDC42; Combined immunodeficiency; Dedicator of cytokinesis; DOCK2; DOCK8; Hyper IgE syndrome; Primary immunodeficiency; RAC1; STAT3; AR-HIES; autosomal recessive hyper IgE syndrome; AD-HIES; autosomal dominant hyper IgE syndrome; CDC42; cell divisi
Noonan syndrome-causing genes: Molecular update and an assessment of the mutation rate
Keywords: فاکتور تبادل گوانین; Molecular etiology; MAP kinase signaling pathways; Mutation rate; Noonan syndrome; PTPN11; RAS family; CDC25; cell division cycle 25; CHD; congenital heart defects; CR; conserved region; CRD; cysteine-rich domain; GAP; GTPase activating protein; GDP; guan
The Rho guanine exchange factor RHGF-2 acts through the Rho-binding kinase LET-502 to mediate embryonic elongation in C. elegans
Keywords: فاکتور تبادل گوانین; C. elegans; Embryo; Morphogenesis; Genetics; Guanine exchange factor; Rho
Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells
Keywords: فاکتور تبادل گوانین; EPAC; exchange protein directly activated by cAMP; ROCK; RhoA activated Protein Kinase; PKA; protein kinase A; HUVEC; human umbilical vein endothelial cells; GEF; guanine exchange factor; ERM; ezrin-radixin-moesin family; FERM; 4.1 ezrin-radixin-m
Guanine nucleotide exchange in the ribosomal GTPase EFL1 is modulated by the protein mutated in the Shwachman-Diamond Syndrome
Keywords: فاکتور تبادل گوانین; GTPase; Guanine exchange factor; EFL1; Shwachman-Diamond Syndrome protein;
Localization of Ras signaling complex in budding yeast
Keywords: فاکتور تبادل گوانین; cAMP; 3â²-5â²-cyclic adenosine monophosphate; GEF; guanine exchange factor; GAP; GTPase activating protein; ER; endoplasmic reticulum; PKA; protein kinase A; GPCR; G-protein coupled receptor; Saccharomyces cerevisiae; Cdc25; Ira; Adenylate cyclase; Memb
Invadopodia and rolling-type motility are specific features of highly invasive p190bcr-abl leukemic cells
Keywords: فاکتور تبادل گوانین; Cytoskeleton; Invadopodia; Bcr-Abl; Leukemia; Mobility; RhoGTPase; Guanine exchange factor; Invasion; Matrix remodeling
Rab GTPases implicated in inherited and acquired disorders
Keywords: فاکتور تبادل گوانین; ER; endoplasmic reticulum; EEA; early endosome antigen; GDP; guanosine diphosphate; GDI; GDP dissociation inhibitor; GEF; guanine exchange factor; GAP; GTPase activating protein; GLUT4; glucose transporter 4; GTP; guanosine triphosphate; MAPK; mitogen act
The Fc receptor-cytoskeleton complex from human neutrophils
Keywords: فاکتور تبادل گوانین; AEBSF; 4-(2-Aminoethyl) benzenesulfonyl fluoride; CID; Collision-induced dissociation; Da; Dalton; ESI; electro spray ionization; GAP; GTPase activating protein; GEF; guanine exchange factor; HPMI; HEPES Park Memorial Institute; LARC; live-cell affinity r
RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways
Keywords: فاکتور تبادل گوانین; RGS; regulators of G protein signalling; RBD; Ras/Rap binding domain; GPCR; G protein coupled receptor; MAPkinase; Mitogen-activated protein kinases; GPR/GoLoco (GL); G protein regulatory motif; GEF; guanine exchange factor; GDI; guanine nucleotide dissoc
Differential distribution of exchange proteins directly activated by cyclic AMP within the adult rat retina
Keywords: فاکتور تبادل گوانین; PKA; immunohistochemistry; PDE; CNG; Rap; H89; BCA; bicinchoninic acid; cAMP; cyclic AMP; cDNA; complimentary DNA; cGMP; cyclic guanosine monophosphate; ChAT; choline acetalytransferase; CNB; cyclic nucleotide binding site; CNG; cyclic nucleotide gated ch
Expression and function of phospholipase C in breast carcinoma
Keywords: فاکتور تبادل گوانین; Phosphoinositide-specific phospholipase C; (PLC); DMEM; Dulbecco's modified essential media; Foxn1; forkhead transcription factor N1; GDP; guanosine diphosphate; GTP; guanosine triphosphate; GEF; guanine exchange factor; PGK1; phosphoglycerate 1-kinase; P
Highlighting the role of Ras and Rap during Dictyostelium chemotaxis
Keywords: فاکتور تبادل گوانین; Dictyostelium; Chemotaxis; Ras; Rap; Guanine exchange factor; GTP-binding protein;
Entamoeba histolytica: Identification of EhGPCR-1, a novel putative G protein-coupled receptor that binds to EhRabB
Keywords: فاکتور تبادل گوانین; GDI; GDP-dissociation inhibitor; GEF; guanine exchange factor; GPCRs; G protein-coupled receptors; ORF; open reading frame; SD; synthetic dropout medium; TM; transmembranal; Entamoeba histolytica; EhRabB; GPCRs; Phagocytosis; Rab GTPase;
Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain
Keywords: فاکتور تبادل گوانین; EST; expressed sequence tag; GEF; guanine exchange factor; PH; pleckstrin domain; Yeast two-hybrid screen; FLJ protein; Alternative splicing; Perinuclear localization;