دانلود مقالات ISI درباره راهنمای RNA + ترجمه فارسی

درمان های عملکردی برای بهبود زخم های پوستی در اپیدرمولیز بلوز

Functional therapies for cutaneous wound repair in epidermolysis bullosa

Keywords: راهنمای RNA; EB; epidermolysis bullosa; BMZ; basement membrane zone; EBS; epidermolysis bullosa simplex; JEB; junctional epidermolysis bullosa; DEB; dystrophic epidermolysis bullosa; KS; kindler syndrome; DEJ; dermal-epidermal junction; PTC; premature termination codo

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

محاسبه مقیاس و حافظه در سلول های زنده

Scaling computation and memory in living cells

Keywords: راهنمای RNA; Recombinase-based gene circuits; CRISPR-based gene circuits; Cellular computing; ADC; analog-to-digital converter; att; attachment sites; BLADE; Boolean logic and arithmetic through DNA excision; Cas; CRISPR-associated nuclease; CRISPR; clustered regularl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

دستکاری ژنتیکی در محصولات: چالش ها و فرصت ها

Genetic manipulations in crops: Challenges and opportunities

Keywords: راهنمای RNA; Bt; Bacillus thuringiensis; CRISPR/Cas9; Clustered Regularly Interspaced Short Palindromic Repeat; DSB; Double stranded breaks; GM; Genetically modified; gRNA; Guide RNA; GURTs; Gene Use Restriction Technologies; HR; Homologous recombination; NHEJ; Non-ho

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

ترجمه ژنتیک فیبروز کیستیک به پزشکی شخصی

Translating the genetics of cystic fibrosis to personalized medicine

Keywords: راهنمای RNA; AAV; Adeno associated virus; ABC; ATP-binding cassette; ACMG; American College Medical Genetics; AH; Ancestral Haplotype; ASL; airway surface liquid; ATP; Adenosine triphosphate; cas; CRISPR associated; CF; Cystic fibrosis; CFTR; Cystic Fibrosis Transmemb

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی استفاده از ویرایش ژنوم در مطالعه کاهش شنوایی

ReviewThe application of genome editing in studying hearing loss

Keywords: راهنمای RNA; AAV; Adeno-associated virus; ARHL; age-related hearing loss; Cas9; CRISPR-associated nuclease 9; CRISPR; clustered, regularly interspaced, short palindromic repeat; crRNA; CRISPR RNA; dCas9; defective Cas9; DSBs; double-strand breaks; gRNA; guide RNA; HDR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

CRISPy-web: منابع آنلاین برای طراحی sgRNAs برای برنامه های CRISPR

CRISPy-web: An online resource to design sgRNAs for CRISPR applications

Keywords: راهنمای RNA; CRISPR; Cas9; sgRNA; Guide RNA; Genome editing; Genome engineering

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining

Keywords: راهنمای RNA; In vivo gene correction; Microhomology-mediated end-joining (MMEJ); Targeted sequence substitution (TSS); Hereditary tyrosinemia; Homology-directed repair (HDR); HDR; Homology-directed repair; NHEJ; Non-homologous end-joining; MMEJ; Microhomology-mediate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Guide RNA selection for CRISPR-Cas9 transfections in Plasmodium falciparum

Keywords: راهنمای RNA; Plasmodium falciparum; Malaria; DNA transfection; CRISPR-Cas9 design; Multigene families; Guide RNA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis Pigmentosa

Keywords: راهنمای RNA; AAV; adeno-associated virus; adRP; autosomal dominant retinitis pigmentosa; bp; base pair; CRISPR; clustered regularly interspaced short palindromic repeat; CRISPRd; clustered regularly interspaced short palindromic repeats using Cas9 and double guide RNA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer

Keywords: راهنمای RNA; ARE; antioxidant response element; CPT1; carnitine palmitoyltransferase I; CPTII; carnitine palmitoyltransferase II; associated 9 (Cas9); clustered regulatory interspaced short palindromic repeat (CRISPR); DEN; diethyl nitrosamine; DMBA; 7, 12 dimethylben

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Strategies for controlling CRISPR/Cas9 off-target effects and biological variations in mammalian genome editing experiments

Keywords: راهنمای RNA; CRISPR; clustered regularly interspaced short palindromic repeats; gRNA; guide RNA; OTE; off-target effects; KO; knock out; NHEJ; non-homologous end joining; KI; knock in; HDR; homology directed repair; GOI; gene of interest; LOI; locus of interest; iPSC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

CRMP2-Neurofibromin Interface Drives NF1-related Pain

Keywords: راهنمای RNA; ANOVA; analysis of variance; AP; action potential; Cas9; CRISPR-associated protein-9 nuclease; CaV2.2; N-type voltage-gated calcium channel; CGRP; calcitonin gene-related peptide; CNRP1; CRMP2-neurofibromin regulating peptide 1; CRISPR; clustered regula

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

In vivo methods for acute modulation of gene expression in the central nervous system

Keywords: راهنمای RNA; AAV; adeno-associated viruses; ADV; adenoviruses; ApoE; apolypoprotein E; BBB; blood brain barrier; cap; encapsulation; Cas9; CRISPR associated protein 9; cDNA; coding DNA; CMV; cytomegalovirus; CNS; central nervous system; CNT; carbon nanotubes; CRISPR;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Guide RNA genes up-regulated in Leishmania infantum metacyclic promastigotes

Keywords: راهنمای RNA; Minicircles; RNA-editing; Guide RNA; Kinetoplastids; Leishmania infantum; Metacyclic promastigotes; Peanut agglutinin;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Pluripotent stem cell models of Blau syndrome reveal an IFN-γ-dependent inflammatory response in macrophages

Keywords: راهنمای RNA; Blau syndrome; nucleotide-binding oligomerization domain 2; nuclear factor κB; IFN-γ; disease-specific induced pluripotent stem cells; ChIP; Chromatin immunoprecipitation; DAPI; 4′-6-Diamidino-2-phenylindole dihydrochloride; gRNA; Guide RNA; GSEA; Gen

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Highly efficient genome editing by homology-directed repair using Cas9 protein in Ceratitis capitata

Keywords: راهنمای RNA; ssODN-mediated homology-directed repair; CRISPR-Cas9 ribonucleoprotein complexes; Mediterranean fruit fly; Tephritids; Sterile insect technique; BFP; blue fluorescent protein; bp; base pair(s); Cas; CRISPR associated; CRISPR; Clustered Regularly Interspac

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Efficient transgene insertion in a pseudorabies virus vector by CRISPR/Cas9 and marker rescue-enforced recombination

Keywords: راهنمای RNA; ASFV; African swine fever virus; BAC; bacterial artificial chromosome; Cas9; CRISPR associated protein 9; CRISPR; clustered regularly interspaced short palindromic repeats; DSB; double strand break; EGFP; enhanced green fluorescent protein; FBS; fetal bov

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

The potential and challenges of CRISPR-Cas in eradication of hepatitis B virus covalently closed circular DNA

Keywords: راهنمای RNA; CHB; chronic hepatitis B; HBV; hepatitis B virus; NA; nucleos(t)ide analogue; cccDNA; covalently closed circular DNA; guide RNA; gRNA; NTCP; sodium taurocholate cotransporting polypeptide; RC-DNA; relaxed circular DNA; pgRNA; pregenomic RNAs; HBsAg; HBV s

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus

Keywords: راهنمای RNA; Gene-knockout pigs; CD163; Highly pathogenic PRRSV; CRISPR/Cas9; SCNT; Antiviral breeding; AF; Alexa Fluor; DPI; day post inoculation; gRNA; guide RNA; Hb; Hemoglobin; Hp; haptoglobin; HP-PRRSV; highly pathogenic porcine reproductive and respiratory syndr

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells

Keywords: راهنمای RNA; AAV; Adeno-Associated Virus; CRISPR; clusters of regularly interspaced short palindromic repeats; DBDs; DNA binding domains; gRNA; guide RNA; HAC; homology Arm Cassette; HRP; Horse Radish Peroxidase; PAM; Protospacer Adjacent Motif; TAL; Transcription act

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

A two-plasmid inducible CRISPR/Cas9 genome editing tool for Clostridium acetobutylicum

Keywords: راهنمای RNA; aTc; anhydrotetracycline; CRISPR; Clustered regularly interspaced short palindromic repeats; Cas; CRISPR-associated proteins; Cas9n; Cas9 nickase; DSB; Double-strand break; gDNA; genomic DNA; gRNA; guide RNA; HR; Homologous recombination; NHEJ; Non-homolo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting

Keywords: راهنمای RNA; Islet; α-cell; Enteroendocrine L-cell; Glucagon; GLP1; CRISPR; Cre; Cre recombinase; CreERT2; tamoxifen-inducible Cre recombinase-estrogen receptor fusion protein; CRISPR; clustered regularly interspaced short palindromic repeat; DAPI; 4′,6-diamidino-2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA

Keywords: راهنمای RNA; CRISPR; clustered regularly interspaced short palindromic repeats; CAS9; CRISPR associated protein; gRNA; guide RNA; PAM; protospacer adjacent motif; RNP; ribonucleoprotein; HDR; homology directed repair; hESCs; human embryonic stem cells; NHEJ; non-homol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma

Keywords: راهنمای RNA; Liver Cancer; Protein Kinase A; PKA; Genomic Engineering; Mouse Model; CEA; carcinoembryonic antigen; CRISPR/Cas9; clustered regularly interspaced short palindromic repeats/CRISPR-associated 9; FACS; fluorescence-activated cell sorting; FL-HCC; fibrolamel

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function

Keywords: راهنمای RNA; PSC-Based Model; Neural Development; Enteric Nervous System; Congenital; CD; coding; CNS; central nervous system; CRISPR; clustered regularly interspaced short palindromic repeats; ENCC; enteric neural crest cell; FA; focal adhesion; GDNF; glial cell-deri

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2017 سفارش ترجمه

CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B

Keywords: راهنمای RNA; CRIPSR/Cas9; Pladienolide B; Spliceosome; Pre-mRNA splicing; Drug target validation; Drug discovery; SSNs; Site Specific Nucleases; ZFN; Zing Finger Nucleases; TALENs; Transcription Like Effector Nucleases; CRISPR; Clustered Regulatory Interspaced Short P

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleThe A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS production in colorectal cancer cells via adenosine receptor-independent mechanism

Keywords: راهنمای RNA; PSB603; Off-target effect; Cellular redox state; Reactive oxygen species; Chemotherapy; MTT; 5-FU; Fluorouracil; AR(s); Adenosine receptor(s); CRC; Colorectal cancer; ECAR; extracellular acidification rate; gRNA; guide RNA; HBSS; Hank's Balanced Saline So

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Genome Editing with CRISPR-Cas9: Can It Get Any Better?

Keywords: راهنمای RNA; Genome editing; CRISPR-Cas9 system; Guide RNA;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

U-Insertion/Deletion mRNA-Editing Holoenzyme: Definition in Sight

Keywords: راهنمای RNA; Trypanosoma; mitochondria; RNA editing; guide RNA; polyadenylation; translation

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Investigating RNA editing factors from trypanosome mitochondria

Keywords: راهنمای RNA; Trypanosoma; Mitochondria; Protein complexes; RNA editing; Guide RNA; TUTase; RNA ligase;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing

Keywords: راهنمای RNA; CRISPR; clustered regularly interspaced short palindromic repeat; PAM; protospacer adjacent motif; gRNA; guide RNA; DSB; double strand break; ORF; open reading frame; MMR; mismatch repair; MEP; methylerythritol-phosphate; ssDNA; single-strand DNA; dsDNA;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae

Keywords: راهنمای RNA; CRISPR; clustered regularly interspaced short palindromic repeat; PAM; protospacer adjacent motif; BTS1; Geranylgeranyl pyrophosphate synthase; ROX1; Heme-dependent repressor of hypoxic genes; TALEN; transcription activator-like effector nuclease; gRNA; g

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2015 سفارش ترجمه

U-insertion/deletion RNA editing multiprotein complexes and mitochondrial ribosomes in Leishmania tarentolae are located in antipodal nodes adjacent to the kinetoplast DNA

Keywords: راهنمای RNA; gRNA; guide RNA; kDNA; kinetoplast DNA; RECC; RNA editing core complex; RET1; RNA editing TUTase 1; REH1; RNA editing helicase 1; REMC; RNA editing mediator complex; TAC; tripartite attachment complex; RESC; RNA editing substrate binding complex; GRBC; gR

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

RNA helicases involved in U-insertion/deletion-type RNA editing

Keywords: راهنمای RNA; RNA editing; RNA helicase; African trypanosome; Guide RNA; Mitochondrial gene expression; Editosome;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies

Keywords: راهنمای RNA; CDR; complementarity determining region; gRNA; guide RNA; KREL; kinetoplastid RNA-editing ligase; KREPA6; kinetoplastid RNA-editing interaction protein A6; KRET2; kinetoplastid RNA-editing TUTase 2; KREX2; kinetoplastid RNA-editing 3′ → 5′-exonucl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Complete set of mitochondrial pan-edited mRNAs in Leishmania mexicana amazonensis LV78

Keywords: راهنمای RNA; aa; amino acid; CO; cytochrome c oxidase; Cyb; apocytochrome b; gRNA; guide RNA; kDNA; kinetoplast DNA; mRNA; messenger RNA; MURF; maxicircle unassigned reading frame; ORF; open reading frame; RPS12; ribosomal protein S12; rRNA; ribosomal RNA; tRNA; trans

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه