کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10158281 | 1666522 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer
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کلمات کلیدی
IAPSPAMNHEJgRNADMBAGSTDenNrf2Moringa oleiferaHDRCPT1NQO1HO1second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pIAgNPs - AgNP هاAuNPs - AuNP هاhnRNPs - hnRNP هاNAD(P)H:quinone oxidoreductase 1 - NAD (P) H: کینون اکسیدوردوکتاز 1NFκB - NFKBROS - ROSSouth Africa - آفریقای جنوبیSmac/DIABLO - اسمک / DIABLOTem - این استApoptosis - خزان یاختهایguide RNA - راهنمای RNAHeterogeneous nuclear ribonucleoproteins - ریبونولوپروتئین های هسته ای ناهمگنCancer - سرطانAntiproliferative - ضد انفوزیونnon-homologous end-joining - عدم پیوستن به همولوگantioxidant response element - عنصر پاسخ آنتی اکسیدانnuclear factor (erythroid-derived 2)-like 2 - فاکتور هسته ای (erythroid-derived 2) -like 2nuclear factor kappa B - فاکتور هسته ای کاپا Binhibitors of apoptosis proteins - مهارکننده های پروتئین آپوپتوزیسprotospacer adjacent motif - موتیف مجاور protospacerTransmission electron microscopy - میکروسکوپ الکترونی عبوریGold nanoparticles - نانوذرات طلاSilver nanoparticles - نانوذرات نقرهdiethyl nitrosamine - نیتروزانای دی اتیلARE - هستندheme oxygenase 1 - همای اکسیژناز 1carnitine palmitoyltransferase II - کاردینیتین پالمیتویل ترانسفراز IICarnitine palmitoyltransferase I - کارنتین پالمیتویل ترانسفراز Iglutathione S-transferase - گلوتاتیون S-ترانسفرازReactive oxygen species - گونههای فعال اکسیژن
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Cancer is classified as one of the leading causes of global mortality. It has affected millions of people, often with poor prognosis. Having severe side-effects with conventional chemotherapy, alternate drugs and therapies are actively being investigated. There is a need for innovative drug discovery and design as existing cancer therapies are costly and not readily available. Ayurveda and traditional medicine have utilised natural resources such as plants and trees as part of their regime to treat various illness and diseases with positive outcomes. One such tree is Moringa oleifera (MO). Almost all parts have shown to be effective against several ailments including cancer which was attributed to the bioactive constituents. Targeted therapies had led to the development of nanoparticles which are extremely effective in various biomedical applications due to their small size. Green synthesis of gold nanoparticles have great potential as naturally occurring plants and trees such as MO can be used in the synthesis process. The resultant gold phytonanoparticles are useful in cancer therapies with improved survival rates and quality of life. The review highlights the importance of MO in natural medicine, synthesis of phytonanoparticles and the fundamental role as a potential antiproliferative agent against cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 108, December 2018, Pages 457-466
Journal: Biomedicine & Pharmacotherapy - Volume 108, December 2018, Pages 457-466
نویسندگان
Charlette Tiloke, Krishnan Anand, Robert M. Gengan, Anil A. Chuturgoon,