Keywords: عدم پیوستن به همولوگ; EB; epidermolysis bullosa; BMZ; basement membrane zone; EBS; epidermolysis bullosa simplex; JEB; junctional epidermolysis bullosa; DEB; dystrophic epidermolysis bullosa; KS; kindler syndrome; DEJ; dermal-epidermal junction; PTC; premature termination codo
مقالات ISI عدم پیوستن به همولوگ (ترجمه نشده)
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Keywords: عدم پیوستن به همولوگ; ALK; anaplastic lymphoma receptor tyrosine kinase; ABCB1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; APE1; apurinic/apyimidinic endonuclease 1; AKT; v-akt murine thymoma viral oncogene; BER; base excision repair; BRCA1; breast cancer 1; BRCA2
Keywords: عدم پیوستن به همولوگ; CI; confidence interval; CV; coefficient of variation; DSB; double strand break; DSBR; double strand break repair; HR; homologous recombination; NHEJ; non-homologous end-joining; OR; odds ratio; PBL; peripheral blood lymphocytes; PCR-RFLP; polymerase chai
Keywords: عدم پیوستن به همولوگ; ARS; autonomously replicating sequence; CEN; centromere; CRISPR; Clustered, Regularly Interspaced, Short Palindromic Repeats; DSB; double strand break; GFP; green fluorescent protein; GRAS; Generally Regarded As Safe; gRNA; guide RNA (for CRISPR); HR; hom
Keywords: عدم پیوستن به همولوگ; DSBs; double strand breaks; SSBs; single strand breaks; HR; homologous recombination; NHEJ; non-homologous end-joining; CSA; Cockayne syndrome protein A; CSB; Cockayne syndrome protein B; TC-NER; transcription-coupled nucleotide excision repair; TC-DSBR;
Keywords: عدم پیوستن به همولوگ; DNA double strand breaks; Ionizing radiation; Homologous recombination repair; Alternative end-joining; Non-homologous end-joining; Chromosome translocations;
Keywords: عدم پیوستن به همولوگ; Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex
Keywords: عدم پیوستن به همولوگ; Human DNA ligases; DNA ligase inhibitors; DNA double strand break repair; Non-homologous end-joining
Modified T-cells (using TCR and CTAs), chimeric antigen receptor (CAR) and other molecular tools in recent gene therapy
Keywords: عدم پیوستن به همولوگ; Clinical trials; Disorders; Gene therapy; Molecular biology; Pharmacotherapy; Vector; PID; Primary immunodeficiencies; ADA; Adenosine deaminase; CAR; Chimeric antigen receptors; TCR; T cell receptor; CTAs; Cancer testis antigens; TALEN; Transcription acti
Curcumin sensitizes lymphoma cells to DNA damage agents through regulating Rad51-dependent homologous recombination
Keywords: عدم پیوستن به همولوگ; DSB; double-strand breaks; HR; homologous recombination; NHEJ; non-homologous end-joining; PARP; poly(ADP-ribose) polymerase; PAR; poly(ADP-ribose); MTT; methyl thiazolyl; PI; propidium iodide; SD; standard deviations; SSB; single strand break; γH2AX; ph
Associations of GBP2 gene copy number variations with growth traits and transcriptional expression in Chinese cattle
Keywords: عدم پیوستن به همولوگ; CNVs; Copy number variations; AJ; Angusâ¯Ãâ¯Jiaxian cattle; CDM; Chaidamu cattle; CJ; Charlotteâ¯Ãâ¯Jiaxian; FoSTeS; Fork Stalling and Template Switching; GBP2; guanylate binding protein 2; GWAS; genome-wide association study; JA; Jian cattle; JJ; J
High-throughput system for quantifying and characterizing homologous recombination in Chlamydomonas reinhardtii
Keywords: عدم پیوستن به همولوگ; HR; homologous recombination; NHR; non-homologous recombination; NHEJ; non-homologous end-joining; Chlamydomonas reinhardtii; Nuclear genetic engineering; Homologous recombination; High-throughput screen; Split marker system; Intron homology sequence;
Pol I DNA polymerases stimulate DNA end-joining by Escherichia coli DNA ligase
Keywords: عدم پیوستن به همولوگ; DNA ligase; DNA polymerase; DNA repair; DNA replication; Double strand break repair; Non-homologous end-joining; KLN; Klenow DNA polymerase; KTQ; Klentaq DNA polymerase; BSA; bovine serum albumin; NHEJ; non-homologous end-joining;
Regulation of DNA repair in the absence of classical non-homologous end joining
Keywords: عدم پیوستن به همولوگ; DNA damage signaling; DNA repair; Non-homologous end-joining; Homologous recombination;
Exploring the deleterious SNPs in XRCC4 gene using computational approach and studying their association with breast cancer in the population of West India
Keywords: عدم پیوستن به همولوگ; ARMS; amplification-refractory mutation system; BER; base excision repair; CI; confidence interval; DDG; Gibbs free energy change; HWE; Hardy-Weinberg equilibrium; HMM; Hidden Markov Model; NCBI; National Centre for Biological Information; NHEJ; non-hom
In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining
Keywords: عدم پیوستن به همولوگ; In vivo gene correction; Microhomology-mediated end-joining (MMEJ); Targeted sequence substitution (TSS); Hereditary tyrosinemia; Homology-directed repair (HDR); HDR; Homology-directed repair; NHEJ; Non-homologous end-joining; MMEJ; Microhomology-mediate
Heterologous expression of the human polybromo-1 protein in the methylotrophic yeast Pichia pastoris
Keywords: عدم پیوستن به همولوگ; PBRM1; BAF180; Recombinant protein expression; Pichia pastoris; BRD; Bromodomain; BAH; Bromo-adjacent homology domain; HMG; High mobility group; NHEJ; Non-homologous end-joining; PRR; Post-replication repair; AEX; Anion exchange chromatography; GAP; Glyce
Application and development of genome editing technologies to the Solanaceae plants
Keywords: عدم پیوستن به همولوگ; Genome editing; Nuclease; Targeted mutagenesis; AGL; agamous-like; AID; activation-induced cytidine deaminase; ALOG; Arabidopsis LSH1 and Oryza G1; ANT; anthocyanin mutant; ARF; auxin-response factor; Aux; auxin-induced; BAK; brassinosteroid kinase; BOP;
Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer
Keywords: عدم پیوستن به همولوگ; ARE; antioxidant response element; CPT1; carnitine palmitoyltransferase I; CPTII; carnitine palmitoyltransferase II; associated 9 (Cas9); clustered regulatory interspaced short palindromic repeat (CRISPR); DEN; diethyl nitrosamine; DMBA; 7, 12 dimethylben
Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib
Keywords: عدم پیوستن به همولوگ; PARP; PARG; Tankyrase; Radiosensitization; Homologous recombination; Non-homologous end-joining;
Highly efficient genome editing by homology-directed repair using Cas9 protein in Ceratitis capitata
Keywords: عدم پیوستن به همولوگ; ssODN-mediated homology-directed repair; CRISPR-Cas9 ribonucleoprotein complexes; Mediterranean fruit fly; Tephritids; Sterile insect technique; BFP; blue fluorescent protein; bp; base pair(s); Cas; CRISPR associated; CRISPR; Clustered Regularly Interspac
Genome-scale CRISPR pooled screens
Keywords: عدم پیوستن به همولوگ; Genome engineering; Genetic screens; CRISPR; Cas9; Noncoding; Cancer; RNAi; RNA interference; CRISPR; clustered regularly interspaced short palindromic repeats; sgRNA; single-guide RNA; DSB; double-strand break; NHEJ; non-homologous end-joining; PCR; poly
Increasing genomic instability during cancer therapy in a patient with Li-Fraumeni syndrome
Keywords: عدم پیوستن به همولوگ; CPC; choroid plexus carcinoma; DSBs; double-strands breaks; LFS; Li-Fraumeni syndrome; mFISH; multicolour fluorescence in-situ hybridization; NHEJ; non-homologous end-joining; SEM; scanning electron microscopy; TEM; transmission electron microscopy; γH2A
DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD)
Keywords: عدم پیوستن به همولوگ; 9-1-1 complex; complex of Rad9 Rad1 and Hus1 proteins; A2E; N-retinylidene-N-retinylethanol-amine; AtRal; all-trans retinal; AMD; age-related macular degeneration; AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATM; ataxia-telangiectasia
Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation
Keywords: عدم پیوستن به همولوگ; Genome editing; Non-homologous end-joining; Homology-directed repair; Off-target effects;
Deletion of ligD significantly improves gene targeting frequency in the lignocellulolytic filamentous fungus Penicillium oxalicum
Keywords: عدم پیوستن به همولوگ; DNA ligase IV; Gene targeting; Homologous integration; Non-homologous end-joining; Selectable marker;
Genetic variants of the DNA repair genes from Exome Aggregation Consortium (EXAC) database: significance in cancer
Keywords: عدم پیوستن به همولوگ; AP; Apurinic/Apyrimidinic; BER; Base excision repair; dbSNP; Single Nucleotide Polymorphism database; DNA; Deoxyribonucleic acid; DSB; Double-strand break; ExAC; Exome Aggregation Consortium; FA; ;Fanconi Anemia; GGR; Global Genomic Repair; GWAS; Genome W
Cleavage of Ku80 by caspase-2 promotes non-homologous end joining-mediated DNA repair
Keywords: عدم پیوستن به همولوگ; Ku80 cleavage; Caspase-2; DNA double strand breaks; Non-homologous end-joining;
CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B
Keywords: عدم پیوستن به همولوگ; CRIPSR/Cas9; Pladienolide B; Spliceosome; Pre-mRNA splicing; Drug target validation; Drug discovery; SSNs; Site Specific Nucleases; ZFN; Zing Finger Nucleases; TALENs; Transcription Like Effector Nucleases; CRISPR; Clustered Regulatory Interspaced Short P
Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance
Keywords: عدم پیوستن به همولوگ; DNA double-strand breaks; Non-homologous end-joining; Acetylation; DNA-PKcs;
Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation
Keywords: عدم پیوستن به همولوگ; PTEN; Double-strand breaks; Non-homologous end-joining; Homologous recombination; Ku70; Poly(ADP-ribosyl)ation;
The non-homologous end-joining pathway of S. cerevisiae works effectively in G1-phase cells, and religates cognate ends correctly and non-randomly
Keywords: عدم پیوستن به همولوگ; Double strand breaks; Non-homologous end-joining; DSBs; NHEJ; G1-phase; Cell cycle; Yeast; Karyotype; Translocation
Asparagine 326 in the extremely C-terminal region of XRCC4 is essential for the cell survival after irradiation
Keywords: عدم پیوستن به همولوگ; DNA double-strand break repair; Non-homologous end-joining; XRCC4; Extremely C-terminal region; Nuclear export signal; Leptomycin B;
Research PaperHead and Neck OncologyThe role of XRCC6/Ku70 in nasopharyngeal carcinoma
Keywords: عدم پیوستن به همولوگ; genotype; immunohistochemistry; nasopharyngeal carcinoma; non-homologous end-joining; polymorphism; real-time quantitative reverse transcription; XRCC6/Ku70;
Differential DNA repair pathway choice in cancer cells after proton- and photon-irradiation
Keywords: عدم پیوستن به همولوگ; Photon irradiation; Proton irradiation; Non-homologous end-joining; Homologous recombination; NU7026;
Human RAD50 makes a functional DNA-binding complex
Keywords: عدم پیوستن به همولوگ; MR(N) complex; Scanning force microscopy; Atomic force microscopy; DNA break repair; RAD50 purification; MR(N); MRE11-RAD50-(NBS1) protein complex; SFM; scanning force microscopy; HR; homologous recombination; NHEJ; non-homologous end-joining;
Lysine 271 but not lysine 210 of XRCC4 is required for the nuclear localization of XRCC4 and DNA ligase IV
Keywords: عدم پیوستن به همولوگ; DNA double-strand break repair; Non-homologous end-joining; XRCC4; DNA ligase IV; Nuclear localization; DAPI; 4,6-diamidino-2-phenylindole dihydrochloride; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; D-PBS(â); Ca2+- and Mg2+-free Dulbecco'
ATR signaling cooperates with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam
Keywords: عدم پیوستن به همولوگ; IR; ionizing radiation; LET; linear energy transfer; HRS; hyper-radiosensitivity; IRR; induced radioresistance; DSB; DNA double strand break; ATM; ataxia telangiectasia mutated homolog; ATR; ataxia telangiectasia and Rad3 related; DNA-PKcs; DNA-dependent
Immunocytochemical localization of DNA double-strand breaks in human and rat brains
Keywords: عدم پیوستن به همولوگ; ATM; ataxia telangiectasia, mutated; EDTA; ethylenediaminetetraacetic acid; GAD-67; glutamic acid decarboxylase 67; GFAP; glial fibrillary acidic protein; KPBS; potassium phosphate buffer saline; NHEJ; non-homologous end-joining; anterior hypothalamus; co
Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains
Keywords: عدم پیوستن به همولوگ; APLF; aprataxin- and PNK-like factor; PNKP; polynucleotide kinase phosphatase; FHA; forkhead-associated; XRCC1; X-ray repair cross-complementing protein 1; XRCC4; X-ray repair cross-complementing protein 4; PARP-1; poly(ADP-ribose)polymerase 1; NHEJ; non-
Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair
Keywords: عدم پیوستن به همولوگ; Mre11-Rad50-Nbs1; CtIP; Allostery; Double strand break repair; Dynamics; Conformational change; AFM; atomic force microscopy; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; BRCT; BRCA1 C-terminus domain; DSB; DNA
RecQ helicases and PARP1 team up in maintaining genome integrity
Keywords: عدم پیوستن به همولوگ; ARTD; ADP-ribosyltransferase diphtheria toxin-like; BER; base excision repair; BG; Baller-Gerold syndrome; BLM; Bloom syndrome protein; BRCT; BRCA1 C-terminus domain; BS; Bloom syndrome; CPT; camptothecin; dHJ; double Holliday junction; DSB; DNA double-st
Protein ADP-ribosylation and the cellular response to DNA strand breaks
Keywords: عدم پیوستن به همولوگ; DNA double-strand break; DNA single-strand break; Non-homologous end-joining; Homologous recombination; Single-strand break repair; Base excision repair; Poly(ADP-ribose) polymerase;
Even low doses of radiation lead to DNA damage accumulation in lung tissue according to the genetically-defined DNA repair capacity
Keywords: عدم پیوستن به همولوگ; DNA double-strand breaks; Low-dose radiation; Normal tissue toxicity; Lung tissue; 53BP1 foci; Non-homologous end-joining;
The C-terminus of Nej1 is critical for nuclear localization and non-homologous end-joining
Keywords: عدم پیوستن به همولوگ; CTR, C-terminal region; DAPI, 4′,6-diamidino-2-phenylindole; DSBs, double-strand breaks; NHEJ, non-homologous end-joining; PBS, phosphate buffered saline; UTR, untranslated regionDNA repair; Nej1p; Lif1p; Non-homologous end-joining; Double-strand breaks
AtMMS21 regulates DNA damage response and homologous recombination repair in Arabidopsis
Keywords: عدم پیوستن به همولوگ; DSB; double-strand break; NHEJ; non-homologous end-joining; HR; homologous recombination; ATM; ATAXIA-TELANGIECTASIA MUTATED; ATR; ATM/RAD3-RELATED; SMC; structural maintenance of chromosomes; DAG; days after germination; SDSA; synthesis-dependent strand
ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress
Keywords: عدم پیوستن به همولوگ; Replication stress; 53BP1; ATM; ATMIN; MEFs; mouse embryonic fibroblasts; Aph; aphidicolin; IR; ionizing radiation; Gy; Gray; MMS; methyl methanesulfonate; HU; hydroxyurea; NCS; neocarzinostatin; DAPI; diamidino-2-phenylindole; HR; homologous recombinatio
Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs
Keywords: عدم پیوستن به همولوگ; DSBs; DNA double-strand breaks; NHEJ; non-homologous end-joining; HR; homologous recombination; NCS; neocarzinostatin; ATM; ataxia telangiectasia mutated; MDC1; mediator of DNA damage checkpoint; 53BP1; p53-binding protein 1; BRCA1; breast cancer type 1 s
The repair of environmentally relevant DNA double strand breaks caused by high linear energy transfer irradiation - No simple task
Keywords: عدم پیوستن به همولوگ; DNA double strand break repair; High-LET radiation; Alpha particles; HZE particles; Non-homologous end-joining; Artemis; DNA-PK; Ku;
Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells
Keywords: عدم پیوستن به همولوگ; DSB repair; Non-homologous end-joining; Olaparib; Radiosensitivity; PARP1-dependent end-joining;