Keywords: 6-4PPs; pyrimidine(6-4) pyrimidone photoproducts; BER; base excision repair; CMS; cigarette mainstream smoke; CPDs; cyclobutane pyrimidine dimers; CS; cigarette smoke; CSS; cigarette sidestream smoke; DCFHDA; 6-carboxy-2â²,7â²-dichlorodihydrofluorescein
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: AAV; adeno-associated viruses; ADA; adenosine deaminase deficiency; APCs; antigen presenting cells; AuNC; gold nanoclusters; AuNPs; gold nanoparticles; AuNRs; gold nanorods; BBB; blood-brain barrier; Bcl-2; B-cell lymphoma 2; Cas; CRISPR-associated; ChNPs
Keywords: Therapeutic genome editing; Non-viral delivery; Nuclease-mediated genome editing; Oligonucleotide-mediated genome editing; CRISPR/Cas9; Peptide nucleic acid; BBB; blood brain barrier; CMV; cell-derived membrane vesicle; CRISPR; Clustered Regularly Intersp
Keywords: EB; epidermolysis bullosa; BMZ; basement membrane zone; EBS; epidermolysis bullosa simplex; JEB; junctional epidermolysis bullosa; DEB; dystrophic epidermolysis bullosa; KS; kindler syndrome; DEJ; dermal-epidermal junction; PTC; premature termination codo
Keywords: RIBE; radiation-induced bystander effect; TIBE; tumour-induced bystander effect; SCE; sister chromatid exchange; ROS; reactive oxygen species; NO; nitric oxide; NF-kappaB; nuclear factor-kappa B; COX-2; cyclooxygenase-2; FA; Fanconi anaemia; ATM; ataxia-t
Keywords: AA; alopecia areata; CRISPR/Cas9; clustered, regularly interspaced, short palindromic repeat/cas 9; HR; homologous recombination; iPSC; induced pluripotent stem cell; MSC; mesenchymal stromal cell; NHEJ; nonhomologous end-joining; RDEB; recessive dystroph
Keywords: Recombinase-based gene circuits; CRISPR-based gene circuits; Cellular computing; ADC; analog-to-digital converter; att; attachment sites; BLADE; Boolean logic and arithmetic through DNA excision; Cas; CRISPR-associated nuclease; CRISPR; clustered regularl
Keywords: TNR; trinucleotide repeat; HR; homologous recombination; EJ; end joining; DSB; double stranded break; SCR; sister chromatid recombination; NHEJ; non homologous end-joining; MMEJ; microhomology-mediated end-joining; DM1; myotonic Dystrophy type I; HD; Hunt
Keywords: CRISPR-Cas9; Kluyveromyces lactis; Kluyveromyces marxianus; Scheffersomyces stipitis; Yarrowia lipolytica; Hansenula polymorpha; Pichia pastoris; HR; homologous recombination; NHEJ; nonhomologous end-joining; DSB; double strand break; CRISPR; Clustered re
Keywords: REM; RNA-guided endonuclease mediated; EEM; Engineered endonuclease mediated; CRISPR/Cas; Clustered regularly interspersed short palindromic repeats/ CRISPR associated sequence; TALE; Transcription Activator-like Effectors; TALEN; Transcription Activator-
Keywords: ATM; ataxia-telangiectasia mutated; BCL2L1; BCL2 like 1; CGH; comparative genomic hybridization; CHK; checkpoint kinase 1; CIN; chromosomal instability; CNVs; copy number variations; DNMT3B; DNA methyltransferase 3B; DPPA3; developmental pluripotency asso
Keywords: Bt; Bacillus thuringiensis; CRISPR/Cas9; Clustered Regularly Interspaced Short Palindromic Repeat; DSB; Double stranded breaks; GM; Genetically modified; gRNA; Guide RNA; GURTs; Gene Use Restriction Technologies; HR; Homologous recombination; NHEJ; Non-ho
Keywords: ALK; anaplastic lymphoma receptor tyrosine kinase; ABCB1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; APE1; apurinic/apyimidinic endonuclease 1; AKT; v-akt murine thymoma viral oncogene; BER; base excision repair; BRCA1; breast cancer 1; BRCA2
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AT; ataxia telangiectasia; BER; base excision repair; BFB; breakage-fusion-bridge; BMDCs; bone marrow-derived cells; BS; Bloom syndrome; CIN; chromosome instability; CNS; central nervous syste
Keywords: MN; micronuclei; MNE; micronucleated erythrocytes; MNEF; micronucleated erythrocytes frequency; SSB; single-strand break; DSB; double-strand break; TE; total erythrocytes; BM; body mass; ML; maximum longevity; NHEJ; non-homologous end joining; HR; homolog
Keywords: CI; confidence interval; CV; coefficient of variation; DSB; double strand break; DSBR; double strand break repair; HR; homologous recombination; NHEJ; non-homologous end-joining; OR; odds ratio; PBL; peripheral blood lymphocytes; PCR-RFLP; polymerase chai
Keywords: HPCs; hepatic progenitor cells; mtROS; mitochondrial reactive oxygen species; DEN; diethylnitrosamine; SPCs; stem/progenitor cells; HSCs; hematopoietic stem cells; NSCs; neural stem cells; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum;
Keywords: ARS; autonomously replicating sequence; CEN; centromere; CRISPR; Clustered, Regularly Interspaced, Short Palindromic Repeats; DSB; double strand break; GFP; green fluorescent protein; GRAS; Generally Regarded As Safe; gRNA; guide RNA (for CRISPR); HR; hom
Keywords: DSBs; double strand breaks; SSBs; single strand breaks; HR; homologous recombination; NHEJ; non-homologous end-joining; CSA; Cockayne syndrome protein A; CSB; Cockayne syndrome protein B; TC-NER; transcription-coupled nucleotide excision repair; TC-DSBR;
Keywords: DSB; double-strand breaks; HR; homologous recombination; ssDNA; single-stranded DNA; NAHR; non-allelic homologous recombination; SSA; single-strand annealing; VDE; VMA1-derived homing endonuclease; NHEJ; nonhomologous end joining; MMEJ; microhomology-medi
Keywords: DSB; double-strand break; HR; homologous recombination; HDR; homology-directed repair; BIR; break-induced replication; NHEJ; nonhomologous end-joining; Alt-NHEJ; alternative-NHEJ; MMEJ; microhomology-mediated end-joining; ssDNA; single-stranded DNA; Doubl
Keywords: Cancer stem cell; Chemotherapy; Chemoresistance; Targeted therapy; 5-FU; 5-fluorouracil; ABCT; ATP-binding cassette transporter; ALDH; Aldehyde dehydrogenase; AML; Acute myeloid leukemia; ASC; Adult stem cell; BCRP or ABCG; Breast cancer resistance protei
Keywords: Chromosome condensation; Endoreplication; Genome chaos; Replication; Re-replication; APC; Anaphase Promoting Complex; BIR; Break-induced replication; DPP; developmentally programmed polyploidy; GCS; generalized chromosome shattering; GINS; go-ichi-ni-san;
Keywords: Severe combined immunodeficiency; radiation sensitivity; hematopoietic cell transplantation; nonhomologous end joining; DNA repair; ART-SCID; Artemis-deficient severe combined immunodeficiency; ATG; Antithymocyte globulin; DNA-PKcs; DNA-dependent protein
Keywords: nt; nucleotide; dNTP; deoxyribonucleoside triphosphate; rNTP; ribonucleoside triphosphate; pol; DNA polymerase; RNase H; ribonuclease H; Top1; topoisomerase 1; Fen1; flap endonuclease 1; PCNA; proliferating cell nuclear antigen; Exo1; exonuclease 1; Cho;
Keywords: NHEJ; HR; I-SceI; DSB repair;
Keywords: Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Keywords: 17-AAG; 17-(Allylamino)-17-demethoxygeldanamycin; 17-DMAG; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin; AKT; v-akt murine thymoma viral oncogene homolog; APC; antigen presenting cell; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia
Keywords: PI3K/Akt; DNA repair; NHEJ; DNA-PKcs; Ionizing radiation; Radiotherapy;
Keywords: Engineered nuclease; ZFN; TALEN; RGEN; NHEJ; Knockout mouse; Microinjection
Keywords: ATM; ataxia telangiectasia-mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; CI; combination index; CLL; chronic lymphocytic leukemic cells; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit;
Keywords: DNA damage; DNA repair; Radiation sensitivity; DNA repair pathways; Polymorphisms; OTM; Olive tail moment; %tail-DNA; percent DNA in the tail; DRC; DNA repair capacity; DMSO; dimethylsulfoxide; PBS; phosphate-buffered saline; PBSF; phosphate-buffered sali
Keywords: AD; Alzheimer's disease; AP site; apurinic/apyrimidinic site; APE1; apurinic/apyrimidinic endonuclease 1; Aβ; amyloid beta; BER; base excision repair; CaMKII; Ca2 +/Calmodulin-Dependent Protein Kinase II; CDK; cyclin-dependent kinase; CREB; cAMP respons
Keywords: Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex
Curcumin sensitizes lymphoma cells to DNA damage agents through regulating Rad51-dependent homologous recombination
Keywords: DSB; double-strand breaks; HR; homologous recombination; NHEJ; non-homologous end-joining; PARP; poly(ADP-ribose) polymerase; PAR; poly(ADP-ribose); MTT; methyl thiazolyl; PI; propidium iodide; SD; standard deviations; SSB; single strand break; γH2AX; ph
Modified T-cells (using TCR and CTAs), chimeric antigen receptor (CAR) and other molecular tools in recent gene therapy
Keywords: Clinical trials; Disorders; Gene therapy; Molecular biology; Pharmacotherapy; Vector; PID; Primary immunodeficiencies; ADA; Adenosine deaminase; CAR; Chimeric antigen receptors; TCR; T cell receptor; CTAs; Cancer testis antigens; TALEN; Transcription acti
The Implications of CRISPR-Cas9 Genome Editing for IR
Keywords: CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; DSB; double-strand break; HDR; homology-directed repair; HR; homologous recombination; NHEJ; nonhomologous end-joining; PAM; protospacer-adjacent motif; sgRNA; single guide RNA;
Pol I DNA polymerases stimulate DNA end-joining by Escherichia coli DNA ligase
Keywords: DNA ligase; DNA polymerase; DNA repair; DNA replication; Double strand break repair; Non-homologous end-joining; KLN; Klenow DNA polymerase; KTQ; Klentaq DNA polymerase; BSA; bovine serum albumin; NHEJ; non-homologous end-joining;
Associations of GBP2 gene copy number variations with growth traits and transcriptional expression in Chinese cattle
Keywords: CNVs; Copy number variations; AJ; Angusâ¯Ãâ¯Jiaxian cattle; CDM; Chaidamu cattle; CJ; Charlotteâ¯Ãâ¯Jiaxian; FoSTeS; Fork Stalling and Template Switching; GBP2; guanylate binding protein 2; GWAS; genome-wide association study; JA; Jian cattle; JJ; J
High-throughput system for quantifying and characterizing homologous recombination in Chlamydomonas reinhardtii
Keywords: HR; homologous recombination; NHR; non-homologous recombination; NHEJ; non-homologous end-joining; Chlamydomonas reinhardtii; Nuclear genetic engineering; Homologous recombination; High-throughput screen; Split marker system; Intron homology sequence;
Exploring the deleterious SNPs in XRCC4 gene using computational approach and studying their association with breast cancer in the population of West India
Keywords: ARMS; amplification-refractory mutation system; BER; base excision repair; CI; confidence interval; DDG; Gibbs free energy change; HWE; Hardy-Weinberg equilibrium; HMM; Hidden Markov Model; NCBI; National Centre for Biological Information; NHEJ; non-hom
In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining
Keywords: In vivo gene correction; Microhomology-mediated end-joining (MMEJ); Targeted sequence substitution (TSS); Hereditary tyrosinemia; Homology-directed repair (HDR); HDR; Homology-directed repair; NHEJ; Non-homologous end-joining; MMEJ; Microhomology-mediate
Heterologous expression of the human polybromo-1 protein in the methylotrophic yeast Pichia pastoris
Keywords: PBRM1; BAF180; Recombinant protein expression; Pichia pastoris; BRD; Bromodomain; BAH; Bromo-adjacent homology domain; HMG; High mobility group; NHEJ; Non-homologous end-joining; PRR; Post-replication repair; AEX; Anion exchange chromatography; GAP; Glyce
Beyond interstrand crosslinks repair: contribution of FANCD2 and other Fanconi Anemia proteins to the replication of DNA
Keywords: A-EJ; alternative end joing; APH; aphidicolin; BIR; break induced replication; BTRR; BLM helicase/topoisomerase IIIa (TOPOIIIa)/RMI1 and RMI2 cofactors; CFS; common fragile sites; Cis; cisplatin; DEB; diepoxybutane; DSBs; double strand breaks; DSEs; one e
Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer
Keywords: ARE; antioxidant response element; CPT1; carnitine palmitoyltransferase I; CPTII; carnitine palmitoyltransferase II; associated 9 (Cas9); clustered regulatory interspaced short palindromic repeat (CRISPR); DEN; diethyl nitrosamine; DMBA; 7, 12 dimethylben
Application and development of genome editing technologies to the Solanaceae plants
Keywords: Genome editing; Nuclease; Targeted mutagenesis; AGL; agamous-like; AID; activation-induced cytidine deaminase; ALOG; Arabidopsis LSH1 and Oryza G1; ANT; anthocyanin mutant; ARF; auxin-response factor; Aux; auxin-induced; BAK; brassinosteroid kinase; BOP;
Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis Pigmentosa
Keywords: AAV; adeno-associated virus; adRP; autosomal dominant retinitis pigmentosa; bp; base pair; CRISPR; clustered regularly interspaced short palindromic repeat; CRISPRd; clustered regularly interspaced short palindromic repeats using Cas9 and double guide RNA
DNA damage, metabolism and aging in pro-inflammatory T cells
Keywords: EC; endothelial cell; ROS; reactive oxygen species; ATP; adenosine 5â²-triphosphate; ER; endoplasmic reticulum; mtDNA; mitochondrial DNA; ETC; electron transport chain; mROS; mitochondrial ROS; NADPH; nicotinamide adenine dinucleotide phosphate; TNF-α;
Strategies for controlling CRISPR/Cas9 off-target effects and biological variations in mammalian genome editing experiments
Keywords: CRISPR; clustered regularly interspaced short palindromic repeats; gRNA; guide RNA; OTE; off-target effects; KO; knock out; NHEJ; non-homologous end joining; KI; knock in; HDR; homology directed repair; GOI; gene of interest; LOI; locus of interest; iPSC;
Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase
Keywords: XRCC4; X-ray repair cross-complementing group 4; STS; staurosporine; CAD; caspase-activated DNase; ICAD; inhibitor of CAD; SRSF; serine/arginine-rich splicing factor; SRPK; SR protein kinase; Bcl; B-cell lymphoma; CLK; Cdc2-like kinase; Lig4; DNA ligase I