دانلود مقالات ISI درباره Nhej + ترجمه فارسی

The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair

Keywords: APE1; apurinic/apyrimidinic endonuclease; A-T; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; BER; base excision repair; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; DNA double-strand break; ECL; enhanced chemiluminescence; F

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

AtMMS21 regulates DNA damage response and homologous recombination repair in Arabidopsis

Keywords: DSB; double-strand break; NHEJ; non-homologous end-joining; HR; homologous recombination; ATM; ATAXIA-TELANGIECTASIA MUTATED; ATR; ATM/RAD3-RELATED; SMC; structural maintenance of chromosomes; DAG; days after germination; SDSA; synthesis-dependent strand

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Rad51C: A novel suppressor gene modulates the risk of head and neck cancer

Keywords: 5′UTR; 5′ untranslated region; 95%CI; 95% confidence interval; AC; adenocarcinoma; DSBs; double strand breaks; HR; homologous recombination; HBOC; hereditary breast/ovarian cancer; HNSCC; head and neck squamous cell carcinoma; HWE; Hardy-Weinberg eq

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs

Keywords: DSBs; DNA double-strand breaks; NHEJ; non-homologous end-joining; HR; homologous recombination; NCS; neocarzinostatin; ATM; ataxia telangiectasia mutated; MDC1; mediator of DNA damage checkpoint; 53BP1; p53-binding protein 1; BRCA1; breast cancer type 1 s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding

Keywords: BRCT; BRCA1 C-terminal domain; ChIP; chromatin immunoprecipitation; DSB; double-strand break; GAL1-cs; GAL1 promoter cut-site; MRX; Mre11-Rad50-Xrs2 complex; NHEJ; nonhomologous end-joining; PCR; polymerase chain reaction; Double-strand break; Nonhomo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Targeted genome engineering techniques in Drosophila

Keywords: TALEN; CRISPR; Zinc finger nuclease; Gene targeting; Drosophila; Nuclease; NHEJ; Homologous recombination;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress

Keywords: Replication stress; 53BP1; ATM; ATMIN; MEFs; mouse embryonic fibroblasts; Aph; aphidicolin; IR; ionizing radiation; Gy; Gray; MMS; methyl methanesulfonate; HU; hydroxyurea; NCS; neocarzinostatin; DAPI; diamidino-2-phenylindole; HR; homologous recombinatio

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Opportunities for translation: Targeting DNA repair pathways in pancreatic cancer

Keywords: ATR; ATM-Rad3-related; BER; base excision repair; Chk1; checkpoint kinase 1; DDR; DNA damage response and repair; DNA-PKcs; DNA-PK catalytic subunit; DOT1L; DOT1-like; DSB; double strand break; FOLFIRINOX; folinic acid, 5-FU, irinotecan, oxaliplatin; 5-FU

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines

Keywords: DNR; daunorubicin; NHEJ; non-homologous end-joining; MDR; multidrug resistance; DSB; DNA-double-strand break; EMSA; electrophoresis mobility shift assay; ChIP; chromatin immunoprecipitation; Multidrug-resistant cell line; Daunorubicin; NHEJ; DNA-PKcs; DNA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

53BP1: pro choice in DNA repair

Keywords: 53BP1; Rif1; PTIP; NHEJ; HDR; PARPi; telomere; CSR; V(D)J; BRCA1; resection

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Structural insights into NHEJ: Building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time

Keywords: NHEJ; SAXS; MRN; X-ray crystallography;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Functional overlaps between XLF and the ATM-dependent DNA double strand break response

Keywords: Cernunnos; ATM; DNA-PKcs; NHEJ; V(D)J recombination; 53BP1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Phylogenetic analysis and evolutionary origins of DNA polymerase X-family members

Keywords: AP; apurinic/apyrimidinic; ASFV; African swine fever virus; BER; base excision repair; dNTP; deoxynucleoside triphosphate; dRP; deoxyribose phosphate; kDNA; kinetoplast DNA; NHEJ; non-homologous end-joining; PHP; polymerase and histidinol phosphatase; Tdt

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

N-terminal domains of human DNA polymerase lambda promote primer realignment during translesion DNA synthesis

Keywords: 8-oxodG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP; apurinic/apyrimidinic; BER; base excision repair; BSA; bovine serum albumin; BRCT; BRCA1 C-terminal domain; dNTP; 2′-deoxynucleoside 5′-triphosphate; dPolλ; deletion of human DNA polymerase λ (132-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Reprint of “Functional overlaps between XLF and the ATM-dependent DNA double strand break response”

Keywords: Cernunnos; ATM; DNA-PKcs; NHEJ; V(D)J recombination; 53BP1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Interplay of DNA damage and cell cycle signaling at the level of human replication protein A

Keywords: AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; ATRIP; ATR-interacting protein; CDK; cyclin-dependent kinase; CIP; calf intestinal phosphatase; DDR; DNA damage response; DNA-PKcs; D

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - Implication in modification of radiation damage

Keywords: HMGB1; MRN complex; Nrf2-ARE pathway; Radio-modification; TWEAK; IR; ionizing radiation; LET; linear energy transfer; ROS; reactive oxygen species; DSB; double strands break; DDR; DNA damage response; SOD; superoxide dismutase; SSBs; single strand DNA bre

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase inhibitor (HDACI) mechanisms of action: Emerging insights

Keywords: HDAC inhibitor; DNA damage response; DNA repair; Cell cycle checkpoints; Apoptosis; Rational combinations; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; APAF-1; apoptotic protease activating factor 1; ASK1; apoptosis signal-regulating ki

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2014 سفارش ترجمه

C-terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin

Keywords: IR; ionizing radiation; DSB; double-strand break; NHEJ; non-homologous end-joining; PNKP; polynucleotide kinase/phosphatase; LIG4; DNA ligase IV; APLF; aprataxin- and PNK-like factor; BRCT; breast cancer associated 1 C-terminal; FBS; fetal bovine serum; L

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Spatiotemporal dynamics of DNA repair proteins following laser microbeam induced DNA damage - When is a DSB not a DSB?

Keywords: NIR microbeam; near infra-red multiphoton laser microbeam; USX; ultrasoft X-rays; ROS; reactive oxygen species; GFP; green fluorescent protein; YFP; yellow fluorescent protein; RFP; red fluorescent protein; DNA damage; DNA repair; Laser; NHEJ; BER;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting DNA damage response: Threshold, chromatin landscape and beyond

Keywords: DSBs; double strand breaks; γ-H2AX; phosphorylation of histone variant H2AX in Ser139; SUMO; small ubiquitin modifier; ROS; reactive oxygen species; IR; ionizing radiation; Tip60; Tat-interactive 60; HAT; histone acetyltransferase; HDAC; histone deacetyl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up

Keywords: bp; base-pair; DDR; DNA damage response; DNA-PKcs; catalytic subunit of the DNA-dependent protein kinase; DSB; DNA Double-Strand Break; HR; homologous recombination; IR; ionizing radiation; IRIF; ionizing radiation induced foci; LET; Linear Energy Transfe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

DNA double‐strand break response in stem cells: Mechanisms to maintain genomic integrity

Keywords: ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; BRCA1; breast cancer type 1 susceptibility protein; CtBP; C-terminal binding protein; CtIP; CTBP interacting protein; DDR; DNA damage response; DNA-PK; DNA-dependent

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Studying the cerebellar DNA damage response in the tissue culture dish

Keywords: 53BP1; p53 binding protein 1; AOA1/2; ataxia with oculomotor apraxia type 1; A-T; ataxia-telangiectasia; A-TLD; ataxia-telangiectasia-like disorder/disease; ATM; ataxia-telangiectasia, mutated; ATR; ATM- and Rad3-related protein kinase; CaBP; calbindin pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Cadmium sulfate and CdTe-quantum dots alter DNA repair in zebrafish (Danio rerio) liver cells

Keywords: QDs; quantum dots; ZFL; zebrafish liver cells; ROS; reactive oxygen species; BER; base excision repair; NER; nucleotide excision repair; MMR; mismatch repair; NHEJ; non-homologous end joining; Cd; cadmium; CdTe; cadmium telluride; MPA; mercaptopropionic a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Ionizing radiation-induced gene expression changes in TP53 proficient and deficient glioblastoma cell lines

Keywords: GBM; glioblastoma; MT; mutated; WT; wild type; SAM; significance analysis of microarray; FDR; false discovery rate; qPCR; quantitative real-time PCR; SSBs; single-strand breaks; DSBs; double-strand breaks; HRR; homologous recombination repair; NHEJ; non-h

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Association between the XRCC3 T241M polymorphism and risk of cancer: Evidence from 157 case-control studies

Keywords: XRCC3; the X-ray repair cross-complementing group 3; OR; odds ratios; CIs; confidence intervals; BER; base excision repair; NER; nucleotide excision repair; DSBR; double-strand break repair; MMR; mismatch repair; HWE; Hardy-Weinberg equilibrium; HRR; ho

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells

Keywords: AP-1; activator protein; BER; base excision repair; CDK; cyclin-dependant kinase; CDKI; cyclin-dependant kinase inhibitor; CYN; cylindrospermopsin; CYP450; cytochrome P450; DSB; DNA double-strand break; ER; endoplasmic reticulum; GST; glutathione S-transf

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Ionizing radiation and genetic risks. XVII. Formation mechanisms underlying naturally occurring DNA deletions in the human genome and their potential relevance for bridging the gap between induced DNA double-strand breaks and deletions in irradiated germ

Keywords: Genetic risk; DNA damage; DNA deletion; DSB repair; NHEJ; NAHR; DSB;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

DNA repair mechanisms in dividing and non-dividing cells

Keywords: DNA repair; Neural cells; Neurological disorder; Dividing and non-dividing; Endogenous DNA damage; AOA1; ataxia with ocular motor apraxia 1; AP; apurinic/apyrimidinic; APE1; AP endonuclease 1; APTX; aprataxin; ATM; ataxia telangiectasia mutated; CPDs; cyc

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

How life changes itself: The Read-Write (RW) genome

Keywords: Epigenetics; Natural genetic engineering (NGE); Mobile genetic elements (MGEs); Genome inscriptions; nc; non-coding; CDS; coding sequence; CRM; cis-regulatory module; TF; transcription factor; C; cytosine; U; uracil; A; adenine; I; inosine; G; guanine; T;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2013 سفارش ترجمه

A balanced de novo inv(7)(p14.3q22.3) disrupting PDE1C and ATXN7L1 in a 14-year old developmentally delayed boy

Keywords: Developmental disorder; Inversion (7)(p14.3q22.3); ATXN7L1; PDE1C; NHEJ; TTTAAA motif

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in the selenium-induced senescence response

Keywords: ATM; ataxia-telangiectasia mutated; CM-H2DCFDA; 5-(and-6)-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate, acetyl ester; DAPI; 4,6-diamidino-2-phenylindole; DNA-PKcs; the catalytic subunit of DNA-dependent protein kinase; DSBs; double-strand bre

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

p53-dependent radiobiological responses to internalised indium-111 in human cells

Keywords: TRT; Targeted radionuclide therapy; HR; homologous recombination; NHEJ; non-homologous end joining; BER; base excision repair; LET; Linear Energy Transfer; copper-64-ATSM; copper-64-diacyl-bis(N(4)-methylthiosemicarbazone); DMEM; Dulbecco's Modified Eagle

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Repair of chromosomal double-strand breaks by precise ligation in human cells

Keywords: Double-strand break; Precise ligation; NHEJ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of an autonomously replicating sequence in Candida guilliermondii

Keywords: Autonomously replicating sequence; LIG4; NHEJ; Candida guilliermondii

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The BRCT domain and the specific loop 1 of human Polμ are targets of Cdk2/cyclin A phosphorylation

Keywords: DNA polymerase mu; Pol μ; DNA repair; Cdk phosphorylation; Cell cycle regulation; NHEJ

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

A submicroscopic deletion involving part of the CREBBP gene detected by array-CGH in a patient with Rubinstein-Taybi syndrome

Keywords: RSTS; Rubinstein-Taybi syndrome; OMIM; Online Mendelian inheritance in man; CREBBP; CREB binding protein; EP300; E1A binding protein p300; CGH; comparative genomic hybridization; PCR; polymerase chain reaction; Cy3-dUTP; deoxyuridine 5′-triphosphate c

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Enhanced gene replacement frequency in KU70 disruption strain of Stagonospora nodorum

Keywords: Gene disruption; Fungal transformation; Homologous recombination; NHEJ; DSB; SNB

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticlePolymorphisms of DNA repair genes in Korean hepatocellular carcinoma patients with chronic hepatitis B: Possible implications on survival

Keywords: HBV; hepatitis B virus; HCC; hepatocellular carcinoma; SNP; single nucleotide polymorphism; BER; base excision repair; NER; nucleotide excision repair; NHEJ; non-homologous end joining; HBsAg; hepatitis B virus surface antigen; AFP; alpha-fetoprotein; BCL

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The α2 helix in the DNA ligase IV BRCT-1 domain is required for targeted degradation of ligase IV during adenovirus infection

Keywords: Ubiquitin ligase; Adenovirus; DNA Ligase IV; Substrate selection; NHEJ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The BRCA1 alternative splicing variant Δ14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells

Keywords: ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; AURKA; Aurora kinase A; BC; breast cancer; BRCA1/2; breast cancer-associated gene 1/2; BRCT; BRCA1 C-terminal domain; B2M; beta-2-microglobulin; Cdk2; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Telomere dysfunction and chromosome instability

Keywords: A-NHEJ; alternative nonhomologous end joining; B/F/B; breakage/fusion/bridge; C-NHEJ; classical nonhomologous end joining; DSBs; double-strand breaks; GCRs; gross chromosome rearrangements; HSV-tk; herpes simplex thymidine kinase; NHEJ; nonhomologous end

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Réparation des cassures double-brin de l’ADN, un mécanisme peut en cacher un autre : la ligature d’extrémités non homologues alternative

Keywords: Réparation des cassures double-brin de l’ADN; Ligature d’extrémités non homologues; NHEJ; Recombinaison homologue; Instabilité génétique; MutagenèseDNA double-strand break repair; Non-homologous end joining; NHEJ; Homologous recombination; Genetic instabi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Gene regulation in response to DNA damage

Keywords: DNA repair; Homologous recombination; NHEJ; ATM; ATR; BER

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Development of Novel Visual-Plus Quantitative Analysis Systems for Studying DNA Double-Strand Break Repairs in Zebrafish

Keywords: DNA DSB repair; NHEJ; HR; SSA; I-Sce I; ZebrafishDSB, double-strand break; EGFP, enhanced green fluorescent protein; HR, homologous recombination; NHEJ, non-homologous end joining; SSA, single-strand annealing; qPCR, quantitative real-time polymerase chai

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

PARP inhibition potentiates the cytotoxic activity of C-1305, a selective inhibitor of topoisomerase II, in human BRCA1-positive breast cancer cells

Keywords: BER; base excision repair; BRCA1; breast cancer type 1 susceptibility protein; HMC; Hoffman modulation contrast; HR; homologous recombination; NER; nucleotide excision repair; NHEJ; non-homologous end joining; MMP; mitochondrial membrane potential; PARP-1

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

c-Myc Suppression of DNA Double-strand Break Repair

Keywords: HR; homologous recombination; NHEJ; nonhomologous end-joining; DSB; DNA double-strand break; PFGE; pulsed-field gel electrophoresis; siRNA; small interfering RNA; RNAi; RNA interference; DOX; doxycycline; DNA-PKcs; DNA-dependent protein kinase catalytic s

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

Keywords: 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2012 سفارش ترجمه

In vitro studies of cellular response to DNA damage induced by boron neutron capture therapy

Keywords: Damage; DNA; Cell cycle; NHEJ

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه