دانلود مقالات ISI درباره Nhej + ترجمه فارسی

Regulation of DNA repair by non-coding miRNAs

Keywords: miRNAs; DNA damage; DNA repair; Genomic instability; DSB repair; NER; DSB; double strand break; HR; homologous recombination; NHEJ; non-homologous end joining; NER; nucleotide excision repair; BER; base excision repair; TLS; translesion synthesis; FA; Fan

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of extremely low frequency electromagnetic field and cisplatin on mRNA levels of some DNA repair genes

Keywords: Electromagnetic field; Cisplatin; NHEJ; BER; NER; Gene expression;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Modulation of ionizing radiation-induced effects by NU7441, KU55933 and VE821 in peripheral blood lymphocytes

Keywords: Ionizing radiation; Lymphocytes; KU55933; NU7441; VE821; ATM; ataxia-telangiectasia mutated kinase; ATR; ataxia telangiectasia and Rad3-related protein kinase; DMSO; dimethyl sulfoxide; DNA-PK; DNA-dependent protein kinase; DSB; double strand break; Gy; g

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases

Keywords: AID; activation-induced deaminase; APE; apurinic/apyrimidinic endonuclease; BER; base excision repair; bp; base pair; CSR; class switch recombination; D; diversity gene segment; EXO1; exonuclease 1; Ig; immunoglobulin; J; joining gene segment; pol; polyme

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular and immunological characterization of DNA ligase IV deficiency

Keywords: Somatic reversion; Immunodeficiency; LIG4; NHEJ;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of corexit oil dispersants and the WAF of dispersed oil on DNA damage and repair in cultured human bronchial airway cells, BEAS-2B

Keywords: DSBs; Double Strand Breaks; FBS; Fetal Bovine Serum; HR; Homologous Recombination; NER; Nucleotide Excision Repair; NHEJ; Non-Homologous End Joining; PAH; Polycyclic aromatic hydrocarbon; SOA; Secondary Aerosols; SSBs; Singe Strand Breaks; UV; Ultraviolet

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The non-homologous end-joining pathway of S. cerevisiae works effectively in G1-phase cells, and religates cognate ends correctly and non-randomly

Keywords: Double strand breaks; Non-homologous end-joining; DSBs; NHEJ; G1-phase; Cell cycle; Yeast; Karyotype; Translocation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Biochemical characterization of plant Rad52 protein from rice (Oryza sativa)

Keywords: DNA binding; Oryza sativa; OsRad52; Rad52 homologues; Renaturation; Strand annealing; dsDNA; double stranded DNA; HR; homologous recombination; NHEJ; non homologous end joining; OsRad52-2a; Oryza sativa Radiation sensitive 52-2a; ssDNA; single strand DNA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Histone deacetylase inhibitors decrease NHEJ both by acetylation of repair factors and trapping of PARP1 at DNA double-strand breaks in chromatin

Keywords: HDAC; DSB repair; NHEJ; PARP1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Non-DSB clustered DNA lesions. Does theory colocalize with the experiment?

Keywords: BER; Base excision repair; B-NHEJ; backup NHEJ; DDR; DNA damage response; D-NHEJ; referred as canonical or classical NHEJ; DSBR; double-strand break repair; DSBs; DNA Double strand breaks; Flike; Foci-like analysis parameter; IR; Ionizing Radiation; HR; H

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Yap1 and Skn7 genetically interact with Rad51 in response to oxidative stress and DNA double-strand break in Saccharomyces cerevisiae

Keywords: DSB; double-strand break; SSB; single-strand break; ROS; reactive oxygen species; HR; homologous recombination; NHEJ; non-homologous end joining; BER; base excision repair; NER; nucleotide excision repair; PQ; paraquat; PHL; phleomycin; HU; hydroxyurea; M

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

DNA repair by RNA: Templated, or not templated, that is the question

Keywords: DSB; double-strand break; HR; homologous recombination; NHEJ; non-homologous end joining; cDNA; complementary DNA; RT; reverse transcriptase; Ty; transposon-yeast; LINE-1; Long Intersperse Element-1; dsDNA; double-stranded DNA; AGS; Aicardi-Goutières syn

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs

Keywords: House dust mite; asthma; oxidative stress; DNA double-strand breaks; BEAS-2B; cell death; DNA repair; NU7441; AHR; Airway hyperresponsiveness; ATM; Ataxia-telangiectasia mutated; BAL; Bronchoalveolar lavage; CC10; Club cell 10 kDa protein; DCFH-DA; 2,7-D

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Agammaglobulinemia associated to nasal polyposis due to a hypomorphic RAG1 mutation in a 12 years old boy

Keywords: PID; primary immune deficiency; SCID; severe combined immunodeficiency; CVID; common variable immunodeficiency; OS; Omenn syndrome; RAG1; recombination-activating gene 1; RAG2; recombination-activating gene 2; RSSs; recombination signal sequences; DSBs; D

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Advances in therapeutic CRISPR/Cas9 genome editing

Keywords: Cas9; CRISPR-associated protein 9; cccDNA; covalently closed circular DNA; CCR5; chemokine receptor 5; CFTR; cystic fibrosis transmembrane conductance regulator; CRISPRs; clustered regularly interspaced short palindromic repeats; crRNA; CRISPR RNA; Crygc;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Generation of a Double KO Mouse by Simultaneous Targeting of the Neighboring Genes Tmem176a and Tmem176b Using CRISPR/Cas9: Key Steps from Design to Genotyping

Keywords: CRISPR/Cas9; C57BL/6; Double KO; Genotyping; NHEJ; Deletion; Inversion; Off-targets; Mosaicism;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Current status of potential applications of repurposed Cas9 for structural and functional genomics of plants

Keywords: CRISPR; Crop improvement; dCas9; Epigenetics; Gene editing; Gene regulation; CRISPRa; CRISPR activation; CRISPR-Cas; Clustered Regularly Interspaced Short Palindromic Repeats - CRISPR associated proteins; CRISPRi; CRISPR interference; crRNA; CRISPR RNA; D

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

High-resolution genomic assays provide insight into the division of labor between TLS and HDR in mammalian replication of damaged DNA

Keywords: BER; base excision repair; BP-G; benzo[a]pyrene-guanine adduct; CPD; cyclobutane pyrimidine dimer; CRISPR; clustered regularly-interspaced short palindromic repeats; CSTR; complementary strand transfer repair; DDT; DNA damage tolerance; DSB; double strand

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

TDP-43/FUS in motor neuron disease: Complexity and challenges

Keywords: AD; Alzheimer's disease; Ago2; Argonaute 2; ALS; Amyotrophic lateral sclerosis; ALS/PD; amyotrophic lateral sclerosis and Parkinsonism-dementia complex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF3; activating transcription factor 3

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2016 سفارش ترجمه

DNA repair targeted therapy: The past or future of cancer treatment?

Keywords: DNA damage; DNA repair; Cancer; Radiation; Replication protein A; NER; nucleotide excision repair; MMR; DNA mismatch repair; BER; base excision repair; HDR; homology directed repair; FA; Fanconi anemia; HR; homologous recombination; DDR; DNA damage respon

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer TARGETases: DSB repair as a pharmacological target

Keywords: DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel

دانلود رایگان متن کامل مقاله ISI 110 صفحه سال انتشار : 2016 سفارش ترجمه

De novo double reciprocal translocations in addition to partial monosomy at another chromosome: A very rare case

Keywords: CCRs; complex chromosome rearrangements; ABCR; apparently balanced structural chromosome rearrangements; FISH; fluorescence in situ hybridization; NHEJ; nonhomologous end joining; Reciprocal translocation; Apparently balanced chromosome rearrangements; Co

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Suppression of OsKu80 results in defects in developmental growth and increased telomere length in rice (Oryza sativa L.)

Keywords: Rice (Oryza sativa L.); Ku80; Ku70/Ku80 heterodimer; Developmental growth; Telomere; Genome stability; BiFC; bimolecular fluorescence complementation; ChIP; chromatin immuno-precipitation; DSB; double strand break; HR; homologous recombination; NHEJ; non-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Disruption of lig4 improves gene targeting efficiency in the oleaginous fungus Mortierella alpina 1S-4

Keywords: HR; homologous recombination; NHEJ; none homologousend joining; DSBs; DNA double-strand breaks; OA; oleic acid; LA; linoleic acid; GLA; γ-linolenic acid; DGLA; dihomo-γ-linolenic acid; ARA; arachidonic acid; DNA ligase 4 (lig4); Homologous recombination

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Nrf2 promotes survival following exposure to ionizing radiation

Keywords: ARE; antioxidant response element; ARS; acute radiation syndrome; ATM; ataxia telangiectasia mutated; BRCA1; breast cancer type 1 susceptibility protein; ChIP; chromatin immunoprecipitation; CnC; cap 'n׳ collar family of basic leucine zipper transcript

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Human RAD50 makes a functional DNA-binding complex

Keywords: MR(N) complex; Scanning force microscopy; Atomic force microscopy; DNA break repair; RAD50 purification; MR(N); MRE11-RAD50-(NBS1) protein complex; SFM; scanning force microscopy; HR; homologous recombination; NHEJ; non-homologous end-joining;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Targeted mutagenesis and functional analysis of adipokinetic hormone-encoding gene in Drosophila

Keywords: Neuropeptide; Carbohydrate metabolism; Drome-Akh; NHEJ; Stress; Trehalose

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Immunocytochemical localization of DNA double-strand breaks in human and rat brains

Keywords: ATM; ataxia telangiectasia, mutated; EDTA; ethylenediaminetetraacetic acid; GAD-67; glutamic acid decarboxylase 67; GFAP; glial fibrillary acidic protein; KPBS; potassium phosphate buffer saline; NHEJ; non-homologous end-joining; anterior hypothalamus; co

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response

Keywords: 53BP1; p53 binding protein 1; ATM; ataxia-telangiectasia mutated; ATR; ataxia telangiectasia and Rad3 related; BLM; blooms syndrome RecQ helicase-like, human homolog of SGS1; BRCA1; breast cancer 1, early onset; CDC; cell division cycle; CDK; cyclin depen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

ATR signaling cooperates with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam

Keywords: IR; ionizing radiation; LET; linear energy transfer; HRS; hyper-radiosensitivity; IRR; induced radioresistance; DSB; DNA double strand break; ATM; ataxia telangiectasia mutated homolog; ATR; ataxia telangiectasia and Rad3 related; DNA-PKcs; DNA-dependent

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Lysine 271 but not lysine 210 of XRCC4 is required for the nuclear localization of XRCC4 and DNA ligase IV

Keywords: DNA double-strand break repair; Non-homologous end-joining; XRCC4; DNA ligase IV; Nuclear localization; DAPI; 4,6-diamidino-2-phenylindole dihydrochloride; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; D-PBS(−); Ca2+- and Mg2+-free Dulbecco'

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Quality control mechanisms in cellular and systemic DNA damage responses

Keywords: DNA damage; Ageing; Ubiquitin proteasome system; DNA repair; Progeroid syndromes; Genome stability; ARF; adenosine diphosphate ribosylation factor; AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BER; base excis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Radiation-induced hyperproliferation of intestinal crypts results in elevated genome instability with inactive p53-related genomic surveillance

Keywords: NHEJ; Hyperproliferation; Intestinal crypt

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains

Keywords: APLF; aprataxin- and PNK-like factor; PNKP; polynucleotide kinase phosphatase; FHA; forkhead-associated; XRCC1; X-ray repair cross-complementing protein 1; XRCC4; X-ray repair cross-complementing protein 4; PARP-1; poly(ADP-ribose)polymerase 1; NHEJ; non-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Modulation of TCR responsiveness by the Grb2-family adaptor, Gads

Keywords: DAG; diacylglycerolDSB, double strand break; Gads; Grb2-related adaptor downstream of Shc; Indel; insertion and deletion mutation; GFP; green fluorescent protein; Grap; Grb2-related adaptor protein; Grb2; growth factor receptor-bound 2; IRES; internal rib

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives

Keywords: C; Cytosine; DNMT; DNA methyl transferase; BER; Base Excision Repair; NER; Nucleotide Excision Repair; TET; Ten Eleven Translocation protein; 5mC; 5methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; ESC; Embryo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos

Keywords: DSB; double-strand break; ES; embryonic stem (cell); HR; homologous recombination; NHEJ; non-homologous end joining; sg; single guide; TAL; transcription activator-like; TALEN; TAL effector nucleases; ZFN; zinc-finger nucleases; TALENs; Disease model; One

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency

Keywords: DNA double-strand break repair; nonhomologous end-joining; double-strand break repair deficiency; XRCC4/LIG4; immunodeficiency; microcephaly; CID; Combined immunodeficiency; CS; Cockayne syndrome; CSR; Class-switch recombination; DNA-PK; DNA-dependent pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair

Keywords: Mre11-Rad50-Nbs1; CtIP; Allostery; Double strand break repair; Dynamics; Conformational change; AFM; atomic force microscopy; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; BRCT; BRCA1 C-terminus domain; DSB; DNA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9

Keywords: 3-BrPA; 3 bromopyruvate; AOP; adverse outcome pathway; ARF4; ADP-ribosylation factor 4; BFA; brefeldin A; BT; 1,2,4-benzenetriol; CML; chronic myeloid leukemia; COSMID; CRISPR off-target sites with mismatches, insertions, and deletions; CRISPR-Cas9; clust

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Cell cycle regulation of human DNA repair and chromatin remodeling genes

Keywords: MMR; mismatch repair; NER; nucleotide excision repair; BER; base excision repair; DSB; DNA double-strand break; NHEJ; non-homologous end joining; HR; homologous recombination; FA; Fanconi anemia; SS; serum starvation; TT; double thymidine block; NZ; nocod

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

RecQ helicases and PARP1 team up in maintaining genome integrity

Keywords: ARTD; ADP-ribosyltransferase diphtheria toxin-like; BER; base excision repair; BG; Baller-Gerold syndrome; BLM; Bloom syndrome protein; BRCT; BRCA1 C-terminus domain; BS; Bloom syndrome; CPT; camptothecin; dHJ; double Holliday junction; DSB; DNA double-st

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency

Keywords: V(D)J recombination; nonhomologous end-joining; DNA repair; ARTEMIS deficiency; DCLRE1C mutations; severe combined immunodeficiency; A-MuLV; Abelson murine leukemia virus; ExAC; Exome Aggregation Consortium; GFP; Green fluorescent protein; IR; Ionizing ra

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response

Keywords: TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labelling; EdU; 5-ethynyl-2′-deoxyuridine; PI; Propidium iodide; DAPI; 4′,6-diamidino-2-phenylindole; HR; Homologous recombination; NHEJ; Non homologous end joining; SA-β-gal; Senescence asso

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

An overview of microRNAs

Keywords: RISC; RNA induced silencing complex; MCM7; Minichromosome maintenance protein 7; DGCR8; DiGeorge syndrome critical region 8; TRBP; TAR RNA binding protein; NGS; Next generation sequencing; C3PO; Component 3 promoter of RISC; TNRC6; Trinucleotide repeat co

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Genome engineering with TALENs and ZFNs: Repair pathways and donor design

Keywords: ZFNs; TALENs; DNA repair; Gene targeting; NHEJ; Homologous recombination;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatment

Keywords: TNBC; triple negative breast cancers; BRCA1; breast cancer susceptibility gene 1; PARPi; poly(ADP-ribose) polymerase inhibitors; CTSL; cathepsin L; DSBs; double strand breaks; HR; homologous recombination; NHEJ; non homologous end joining; VDR; vitamin D

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

DR-GAS: A database of functional genetic variants and their phosphorylation states in human DNA repair systems

Keywords: GAS; Haplotype; nsSNP; LD; Phosphorylation; BER; base excision repair; NER; nucleotide excision repair; MMR; mismatch repair; HRR; homologous recombination repair; NHEJ; non-homologous end joining; TLS; trans lesion synthesis; DDS; DNA damage signaling; H

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

DNA Ligase IV regulates XRCC4 nuclear localization

Keywords: DNA Ligase IV; XRCC4; NHEJ; DNA repair; V(D)J recombination

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Manipulation of epigenetic factors and the DNA repair machinery for improving the frequency of plant transformation

Keywords: C-NHEJ; canonical NHEJ; DSBs; DNA double-strand breaks; gDNA; genomic DNA; GT; gene targeting; HR; homologous recombination; NHEJ; non-homologous end joining; PTGS; posttranscriptional gene silencing; RNAi; RNA interference; rat; resistant to Agrobacteriu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه