Human relevance of an in vitro gene signature in HaCaT for skin sensitization
Keywords: Skin sensitization; Human relevance; HaCaT; Gene signature;
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Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells
Keywords: Sanguisorba officinalis L.; HaCaT; Keratinocytes; Anti-inflammation; Chemokine; NF-κB/p65SOL, Sanguisorba officinalis L.; ESOL, ethanol extract of SOL roots; MDC, macrophage-derived chemokine; TARC, thymus and activation regulated chemokine; RANTES, regul
Effects of topical corticosteroids on cell proliferation, cell cycle progression and apoptosis: In vitro comparison on HaCaT
Keywords: HaCaT; Keratinocyte; Topical corticosteroid; Proliferation; Apoptosis; Cell cycle;
Modulating prime molecular expressions and in vitro wound healing rate in keratinocyte (HaCaT) population under characteristic honey dilutions
Keywords: BSA; Bovine Serum Albumin; DMEM-F12; Delbecco׳s Modified Eagle Media-Nutrient Mixture F12 Ham; DPPH; 2, 2-Diphenyl-1-picryylhydrazyl; EMT; Epithelio-Mesenchymal Transition; FBS; Fetal bovine serum; GAE; Gallic Acid Equivalence; GAPDH; Glyceraldehyde 3-ph
Experimental model for ELF-EMF exposure: Concern for human health
Keywords: AD, Alzheimer’s disease; ELF, extremely low frequency; EMFs, electromagnetic fields; HD, Huntington disease; LF, low frequency; MCP-1, monocyte chemoattractant protein-1; PMA, phorbol-12-myristate-13-acetate; PEMF, pulsed EMFELF-EMF; HaCaT; K562; MCP-1; S
Isolation and characterization of gallic acid and methyl gallate from the seed coats of Givotia rottleriformis Griff. and their anti-proliferative effect on human epidermoid carcinoma A431 cells
Keywords: Givotia rottleriformis; Gallic acid; Methyl gallate; A431 cells; Cyclooxygenases; HaCaT
The oxidation of p-phenylenediamine, an ingredient used for permanent hair dyeing purposes, leads to the formation of hydroxyl radicals: Oxidative stress and DNA damage in human immortalized keratinocytes
Keywords: p-Phenylenediamine; Hair dyes; HaCaT; Oxidative stress; DNA damage
Nuclear redox imbalance affects circadian oscillation in HaCaT keratinocytes
Keywords: TTFL; transcriptional/traslational feedback loops; PRDX1-6; peroxiredoxins 1-6; HaCaT; human adult low calcium temperature keratinocytes; NAC; N-acetyl cysteine; NAM; nicotinamide; Circadian rhythms; HaCaT keratinocytes; Peroxiredoxin 2; Sirt1; Oxidat
Wound healing potential of a dimeric InlB variant analyzed by in vitro experiments on re-epithelialization of human skin models
Keywords: A549; adenocarcinomic human alveolar basal epithelial cells; s.d.; standard deviation; HDF; human dermal fibroblasts; HGF/SF; hepatocyte growth factor/scatter factor; HaCaT; human adult keratinocytes, spontaneously immortalized under low calcium condition
Antioxidants in the prevention of UVB-induced keratynocyte apoptosis
Keywords: HaCaT; UVB; Antioxidants; Apoptosis; Ultrastructure; Caspases
Basic Red 51, a permitted semi-permanent hair dye, is cytotoxic to human skin cells: Studies in monolayer and 3D skin model using human keratinocytes (HaCaT)
Keywords: Temporary hair dye; Basic Red 51; 3D organotipic culture; HaCaT
Can nitroxides evoke the Keap1-Nrf2-ARE pathway in skin?
Keywords: SOD; superoxide dismutase; TPO; Tempo (2,2,6,6-tetramethylpiperidine-1-oxyl); 4-OH-TPO; Tempol (4-hydroxy-Tempo); Nrf2; nuclear factor (erythroid-derived 2)-like 2, NF-E2-related factor; ARE; antioxidant-response element; EpRE; electrophile-response eleme
Fragrance chemicals lyral and lilial decrease viability of HaCat cells' by increasing free radical production and lowering intracellular ATP level: Protection by antioxidants
Keywords: Lyral; Lilial; HaCat; ROS; Complex-I; Complex-II; NAC; Trolox; Lipoic acid;
Esterase activity in excised and reconstructed human skin - Biotransformation of prednicarbate and the model dye fluorescein diacetate
Keywords: Ac; acetone; BM; betamethasone; DMSO; dimethyl sulfoxide; CV; coefficient of variation; FDA; fluorescein diacetate; hCE; human carboxylesterase; HaCaT; human keratinocyte cell line; IL-8; interleukin-8; LDH; lactate dehydrogenase; NHDF; normal human derma
Expressed in high metastatic cells (Ehm2) is a positive regulator of keratinocyte adhesion and motility: The implication for wound healing
Keywords: Wound healing; HaCaT; Keratinocytes; ECIS; Ehm2
MiR-23a regulates DNA damage repair and apoptosis in UVB-irradiated HaCaT cells
Keywords: MiR-23a; HaCaT; UVB
Inactivation of Patched1 in Mice Leads to Development of Gastrointestinal Stromal-Like Tumors That Express Pdgfrα but Not Kit
Keywords: GIST Mouse Model; Ptch Mutation; Active Hh Cascade; Pdgfrα Signaling Cascade; BCC; basal cell carcinoma; BM; bone marrow; DOX; doxycycline; GIST; gastrointestinal stromal tumor; GLI; glioma-associated oncogene homolog; HaCaT; human adult low calcium high
The Hsp90 inhibitor 17-AAG represses calcium-induced cytokeratin 1 and 10 expression in HaCaT keratinocytes
Keywords: Cytokeratin 1 and 10; Involucrin; Hsp90; 17-AAG; Keratinocyte differentiation; HaCaT
HBD-1 and hBD-2 expression in HaCaT keratinocytes stimulated with nicotine
Keywords: Human beta-defensins; hBD; Keratinocyte; HaCaT; Nicotine;
The effects of betamethasone dipropionate and fish oil on HaCaT proliferation and apoptosis
Keywords: Betamethasone dipropionate; Fish oil; EPA; Psoriasis; HaCaT; Cell culture; Apoptosis;
Protein indicators for HaCaT cell damage induced by UVB irradiation
Keywords: UVB; HaCaT; 2D DIGE; HPLC-nESI-MS/MS; Proteomics
PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK)
Keywords: PCB153; 2,2â²,4,4â²,5,5â² hexachlorobiphenyl; HaCaT; Immortalized human skin keratinocytes; NFK; normal human foreskin keratinocytes; Polychlorinated biphenyls (PCBs); Telomere; Telomerase; Superoxide; Cell growth; Skin keratinocytes;
A step further toward glyphosate-induced epidermal cell death: Involvement of mitochondrial and oxidative mechanisms
Keywords: HaCaT; Glyphosate; Apoptosis; Flow cytometry; Reactive oxygen species; Mitochondrial membrane potential
Trichloroethanol up-regulates matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in HaCaT cells
Keywords: Trichloroethanol; Matrix metalloproteinases; Tissue inhibitors of metalloproteinases; HaCaT;
Typha latifolia L. fruit polysaccharides induce the differentiation and stimulate the proliferation of human keratinocytes in vitro
Keywords: AGP; arabinogalactan protein; AEC; anion exchange chromatography; CK; cytokeratin; FCS; fetal calf serum; HaCaT; human adult low calcium high temperature keratinocyte; NaPB; sodium phosphate buffer; NHDF; normal human dermal fibroblasts; NHEK; normal huma
Ellagitannins from Phyllanthus muellerianus (Kuntze) Exell.: Geraniin and furosin stimulate cellular activity, differentiation and collagen synthesis of human skin keratinocytes and dermal fibroblasts
Keywords: BrdU; bromodeoxyuridine; ESI; electrospray ionization; FCS; fetal calf serum; HaCaT; Human adult low calcium high temperature keratinocyte cell line; LDH; lactate dehydrogenase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NHDF; prim
HPV E6 proteins target Ubc9, the SUMO conjugating enzyme
Keywords: SUMO; Ubc9; Human papillomavirus; E6; HaCaT; Proteomics
HaCaT keratinocytes express functional receptors for thyroid-stimulating hormone
Keywords: HaCaT; Keratinocytes; Thyroid-stimulating hormone; Receptor;
Cobalt toxicity: Chemical and radiological combined effects on HaCaT keratinocyte cell line
Keywords: Cobalt; HaCaT; Combined chemical and radiochemical toxicity; DNA damage; Additive effects
Phenotypic effects of HPV-16 E2 protein expression in human keratinocytes
Keywords: Papillomavirus; HPV-16; E2 protein; HaCaT; Differentiation
Sustained prolonged topical delivery of bioactive human insulin for potential treatment of cutaneous wounds
Keywords: Wound healing; Insulin; Microspheres; L6 myoblasts; Controlled release; HaCaT; PLGA
Intracellular localisation, geno- and cytotoxic response of polyN-isopropylacrylamide (PNIPAM) nanoparticles to human keratinocyte (HaCaT) and colon cells (SW 480)
Keywords: Nanotoxicology; Aggregation; PNIPAM; HaCaT; SW 480; Lysosomes; Genotoxicity; In vitro
BAG-1 enhances cell–cell adhesion, reduces proliferation and induces chaperone-independent suppression of hepatocyte growth factor-induced epidermal keratinocyte migration
Keywords: Bag-1; Raf-1; Motility; Heat shock protein 70; Hepatocyte growth factor; HaCaT
Structure–activity relationship of seco-tanapartholides isolated from Achillea falcata for inhibition of HaCaT cell growth
Keywords: Structure–activity relationship; Sesquiterpene lactone; Seco-tanapartholide; HaCaT; Cell viability; Asteraceae
Effect of Pinus massoniana bark extract on IFN-γ-induced ICAM-1 expression in HaCaT human keratinocytes
Keywords: Pinus massoniana bark extract; Taxifolin; ICAM-1; HaCaT
Polypeptide from Chlamys farreri modulates UVB-induced activation of NF-κB signaling pathway and protection HaCaT cells from apoptosis
Keywords: Polypeptide from Chlamys farreri (PCF); Nuclear factor kappa B (NF-κB); UVB; HaCaT; Reactive oxygen species (ROS); Apoptosis
Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes
Keywords: IGF-II, insulin-like growth factor II; 12/15-LOX, 12/15-lipoxygenase; PUVA, psoralen plus ultraviolet A12/15-Lipoxygenase (LOX); HaCaT; IGF-II; Psoriasis; UV
Bombesin: A possible role in wound repair
Keywords: HaCat; Bombesin; Wound healing; COX-2;
Inverse inkjet printed gold micro electrodes for the structured deposition of epithelial cells and fibrin
Keywords: Micro electrodes; Inverse inkjet printing; Fibroblasts; HaCaT; Fibrinogen; Fibrin
Co-expression by keratinocytes of migration stimulating factor (MSF) and a functional inhibitor of its bioactivity (MSFI)
Keywords: MSF; NGAL; Lipocalin; Keratinocytes; Fibroblasts; HaCaT; Migration inhibitor; Wound healing; Cancer progression;
Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes
Keywords: Keratinocytes; HaCaT; Cathepsin B; Scratch wounding; Scratch apparatus; ECM remodeling
Mitogen-activated protein kinase kinase 1/extracellular signal-regulated kinase (MEK-1/ERK) inhibitors sensitize reduced glucocorticoid response mediated by TNFα in human epidermal keratinocytes (HaCaT)
Keywords: TNFα; MEK-1/ERK; HaCaT; Human epidermal keratinocytes; Glucocorticoid receptor; Nuclear translocation
Glyphosate-induced antioxidant imbalance in HaCaT: The protective effect of Vitamins C and E
Keywords: HaCaT; Glyphosate-based herbicides; Antioxidant status; Vitamin C; Vitamin E
Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes
Keywords: Antioxidant response element; HaCaT; Signal transduction; Protein kinases; UVBARE, antioxidant response element; GFP, green fluorescent protein; ROS, reactive oxygen species; UVB, ultraviolet B
An interdisciplinary approach to investigate the impact of cobalt in a human keratinocyte cell line
Keywords: Cobalt; HaCaT; Toxicological studies; Structural studies (XAS) and ab initio and thermodynamic modelling; Biochemical speciation; Ion beam analysis; SEC–ICP–AES/UV–VisCFE, colony forming efficiency; CPMD, Car-Parrinello molecular dynamics; Cys, cysteine;
Mechanism of Thymus- and Activation-Regulated Chemokine (TARC)/CCL17 Production and its Modulation by Roxithromycin
Keywords: HaCaT; NFκB; p38; roxithromycin (RXM); thymus- and activation-regulated chemokine (TARC)/CCL17;
Oligo- and polysaccharides exhibit a structure-dependent bioactivity on human keratinocytes in vitro
Keywords: NHK; primary normal human keratinocytes; HaCaT; human adult high calcium low temperature; HMOS; human milk oligosaccharides; CPS; crude polysaccharides; AEC; anion exchange chromatography; LDH; lactatedehydrogenase; TLC; thin layer chromatography; RG; rha