دانلود مقالات ISI درباره Hdac + ترجمه فارسی

Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: Restoring effects of inhibitors of HDACs, p38 MAPK and GSK3β

Keywords: γGCL; gamma-glutamylcysteine ligase; γGCL-C; gamma-glutamylcysteine ligase catalytic subunit; γGCL-M; gamma-glutamylcysteine ligase modulatory subunit; GSH; glutathione; GSK3β; glycogen synthase kinase-3 beta; HAT; histone acetyltransferase; HDAC; his

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes

Keywords: NRSE; neuron-restrictive silencer element; NRSF; neuron-restrictive silencer factor; Zfp; zinc finger protein; DBD; DNA-binding domain; CHF; chronic heart failure; ANP; atrial natriuretic peptide; BNP; brain natriuretic peptide; MeCP2; methyl CpG-binding

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts

Keywords: Histone deacetylase inhibitor; Hdac; Osteoblasts; Zolinza; γH2AX

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Nuclear receptor mRNA expression by HBV in human hepatoblastoma cell lines

Keywords: Nuclear receptor; HCC; HBV; HDAC; Hepatocarcinogenesis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

The role of DDX3 in regulating Snail

Keywords: DDX3; Snail; HDAC; Camptothecin; Metastasis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Sphingolipids and expression regulation of genes in cancer

Keywords: C1P; ceramide 1-phosphate; CAPP; ceramide-activated protein phosphatase; CerK; ceramide kinase; CerS; ceramide synthase; CERT; ceramide transfer protein; COX-2; cyclooxygenase-2; CPPase; ceramide phosphate phosphatase; CSC; cancer stem cell; ES; embryo st

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity

Keywords: Epigenetics; Chromatin; Neuroplasticity; Memory; HDAC; Therapeutics

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting autophagy during cancer therapy to improve clinical outcomes

Keywords: AMPK; AMP activated protein kinase; ATG; autophagy-related genes; Bif-1; endophilin B1; BNIP3; Bcl-2/adenovirus E1B 19 kDa-interacting protein; CML; chronic myeloid leukemia; CQ; chloroquine; DAP1; death-associated protein 1; HCQ; hydroxychloroquine; HDA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Shooting the messenger: Targeting signal transduction pathways in leukemia and related disorders

Keywords: Leukemia; Myeloproliferative disorders; Signaling pathways; Therapeutics; BCR-ABL; JAK2; STAT5; PI 3-kinase; HDAC

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Epigenetic profiling of the antitumor natural product psammaplin A and its analogues

Keywords: Psammaplin A; Epigenetics; HDAC; DNMT; Total synthesis; Natural products

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

IκB kinase-driven nuclear factor-κB activation in patients with asthma and chronic obstructive pulmonary disease

Keywords: Asthma; chronic obstructive pulmonary disease; inflammation; IκB kinase/nuclear factor κB pathway; ATS; American Thoracic Society; COPD; Chronic obstructive pulmonary disease; CSE; Cigarette smoke extract; FP; Fluticasone propionate; FVC; Forced vital c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Analysis of expression and structure of the rat GH-secretagogue/ghrelin receptor (Ghsr) gene: Roles of epigenetic modifications in transcriptional regulation

Keywords: 5-aza-dC; 5-aza-2-deoxycytidine; ChIP; chromatin immunoprecipitation; ERK1/2; extracellular signal-regulated kinase 1/2; DMEM; Dulbecco's modified Eagle's medium; DNMT; DNA methyltransferase; EST; expressed sequence tag; FBS; fetal bovine serum; GH; g

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

Keywords: Hh; Hedgehog; KCASH; KCTD containing; Cullin3 adaptor; suppressor of Hedgehog; HDAC; histone deacetylase; Cul; Cullin;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Urocortin modulates dopaminergic neuronal survival via inhibition of glycogen synthase kinase-3β and histone deacetylase

Keywords: Urocortin; Corticotropin-releasing hormone; Neuropeptide; Dopaminergic neurons; Substantia nigra; cAMP; GSK-3β; HDAC

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Role of Notch and its oncogenic signaling crosstalk in breast cancer

Keywords: 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Redox signaling in cardiac myocytes

Keywords: AIF; apoptosis-inducing factor; ARC; apoptosis repressor with caspase recruitment domain; CamKII; calmodulin kinase II; CTGF; connective tissue growth factor; EB; embryoid body; ECC; excitation-contraction coupling; ER; endoplasmic reticulum; ES; embryo

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

HER2 Interacts With CD44 to Up-regulate CXCR4 via Epigenetic Silencing of microRNA-139 in Gastric Cancer Cells

Keywords: Trastuzumab/Herceptin; Cancer Cell Signaling; Histone Deacetylase; Metastasis-Associated Protein-1; CXCR4; C-X-C chemokine receptor type 4; GSP; gene-specific primer; H3K9; the ninth lysine of histone H3; HDAC; histone deacetylase; HER2; human epidermal g

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2011 سفارش ترجمه

Energy metabolism in adult neural stem cell fate

Keywords: ACC; adenylate cyclase complex; AICAR; aminoimidazole carboxamide ribonucleotide; AMPK; AMP-activated protein kinase; Aspm; abnormal spindle-like microcephaly-associated; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; bHLH;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2011 سفارش ترجمه

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides

Keywords: Histone deacetylase inhibitors; HDAC; Oncology

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Design and synthesis of novel pyrimidine hydroxamic acid inhibitors of histone deacetylases

Keywords: HDAC; Cancer; Optimisation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Selenium-containing analogs of SAHA induce cytotoxicity in lung cancer cells

Keywords: SAHA; HDAC; Lung cancer

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Benzimidazole and imidazole inhibitors of histone deacetylases: Synthesis and biological activity

Keywords: Histone deacetylase inhibitors; HDAC; Oncology

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway

Keywords: DSB; DNA double-strand break; IR; ionizing radiation; HAT; histone acetyltransferase; HDAC; histone deacetylase; H2AXK36Ac; H2AX acetylated on lysine 36; TSA; trichostatin A; H2AX; Acetylation; Chromatin; DNA double-strand break; Histone acetyltransferase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Trichostatin A blocks type I interferon production by activated plasmacytoid dendritic cells

Keywords: Autoimmunity; Cytokines; HDAC; Interferon; Plasmacytoid dendritic cells;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

CommentaryModulation of cell sensitivity to antitumor agents by targeting survival pathways

Keywords: AMPK; AMP-dependent protein kinase; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinases; GRP78; glucose-regulated protein 78; HDAC; histone deacetylase; mTOR; mammalian target of rapamycin; MAPK; mitogen-activated protein kinase; PI3K;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Depolarization induces acetylation of histone H2B in the hippocampus

Keywords: histone acetylation; CaM kinase; ERK; DNA methyltransferase; aCSF; artificial cerebrospinal fluid; CaMK; calcium/calmodulin-dependent kinase; CS; cutting saline; DNMT; DNA methyltransferase; ERK; extracellular signal regulated kinase; HDAC; histone deacet

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Histone modifications, DNA methylation, and Schizophrenia

Keywords: Lymphocyte; DNA methylation; Histone; HDAC; DNMT; GAD67; Reelin; Bipolar; Demethylase; Methyltransferase; Chromatin; Psychosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Short- and medium-chain fatty acids enhance the cell surface expression and transport capacity of the bile salt export pump (BSEP/ABCB11)

Keywords: BCRP; Breast cancer resistance protein; BSEP/Bsep; human/rat isoforms of the bile salt export pump; BRIC; benign recurrent intrahepatic cholestasis; CF/CFTR; cystic fibrosis/cystic fibrosis transmembrane conductance regulator; EGFR; epidermal growth facto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment

Keywords: Neuromuscular disorders; HDAC; HDAC inhibitors; Cardiovascular diseases

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

On the inhibition of histone deacetylase 8

Keywords: HDAC; Computational drug design; Molecular dynamics; Enzymology

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of Tumor and Invasion Suppressor Gene Modulators in Bladder Cancer by Different Classes of Histone Deacetylase Inhibitors Using Reverse Phase Protein Arrays

Keywords: urinary bladder; carcinoma; histone deacetylase inhibitors; genes, suppressor; protein array analysis; DI; concentration interpolation; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; FAK; focal adhesion kinase; HDAC; histone deacetylase; HDACi; HDAC inhib

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

PerspectiveBromodomain Histone Readers and Cancer

Keywords: PTM; post-translational modification; HAT; histone acetyltransferase; HDAC; histone deacetylase; BET; bromodomain and extra-terminal; BRD; bromodomain-containing protein; BRDT; Bromodomain testis associated; NUT; nuclear protein in testis; PROTAC; proteol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleThe NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

Keywords: HDAC; histone acetyltransferase; MMP; matrix metalloproteinase; CCl4; carbon tetrachloride; ChIP; chromatin immunoprecipitation; MAP3K; MAP kinase kinase kinase; IκB; inhibitor of kappa B; p50 NF-κB; HDAC-1; Inflammation; MMP-13; GM-CSF; CXCL10; CCL2; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The influence of mediators of intracellular trafficking on transgene expression efficacy of polymer–plasmid DNA complexes

Keywords: Non-viral gene delivery; Histone deacetylase inhibitors; HDAC; Tubacin; Microtubule; Trichostatin A

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Combined proteasome and histone deacetylase inhibition attenuates epithelial-mesenchymal transition through E-cadherin in esophageal cancer cells

Keywords: 7; ARHGDIB; Rho guanosine diphosphate dissociation inhibitor β gene; BRMS1; breast cancer metastasis suppressor 1 gene; CDH1; gene for E-cadherin; EMT; epithelial-mesenchymal transition; HDAC; histone deacetylase; GAPDH; gene for glyceraldehyde-3-phosp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway

Keywords: Guanine nucleotide exchange factor; Cyclic nucleotides; Small G protein; HDAC; CaMKII; Cardiac hypertrophy;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Immunohistochemical detection of histone deacetylases in endometrial carcinoma: involvement of histone deacetylase 2 in the proliferation of endometrial carcinoma cells

Keywords: Endometrial carcinoma; HDAC; Prognosis; Immunohistochemistry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Epigenetic modification of vomeronasal (V2r) precursor neurons by histone deacetylation

Keywords: mouse; vomeronasal organ; VNO; neurogenesis; epigenetic regulation; AOB; accessory olfactory bulb; HDAC; histone deacetylase; IPA; ingenuity pathway analysis; MUP; mouse urinary protein; OMP; olfactory marker protein; PBS; phosphate buffered saline; PCR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy

Keywords: Small cell lung cancer; Valproate; HDAC; Chemotherapy; Mice;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Vitamin D receptor binds to the ε germline gene promoter and exhibits transrepressive activity

Keywords: Vitamin D receptor; calcitriol; ε germline transcript; class-switch recombination; IgE; histone acetylation; AcH; Acetylated histone; As2O3; Arsenic-(III)-oxide; CH; Constant heavy chain; ChIP; Chromatin immunoprecipitation; CSR; Class-switch recombinati

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Short-Chain Fatty Acids Regulate the Enteric Neurons and Control Gastrointestinal Motility in Rats

Keywords: Butyrate; Neuron; Colon; Monocarboxylate Transporters; ANOVA; analysis of variance; AUC; area under the curve; ChAT; choline acetyltransferase; EFS; electrical field stimulation; ENS; enteric nervous system; GI; gastrointestinal; H3K9; histone H3 lysine 9

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Partitioning of Ba, La, Yb and Y between haplogranitic melts and aqueous solutions: An experimental study

Keywords: Fluid–melt partition coefficients; Barium; REE; Quenched experiments; HDAC; SR-μXRF

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs

Keywords: Tregs; HDAC; Suppression; Therapy; FOXP3

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Inside HDAC with HDAC inhibitors

Keywords: Cancer; HDAC; Inhibitors; Molecular modelling; QSARHDAC, Histone deacetylases; HAT, Histone acetyl transferases; PDB, Protein data bank; NAD, Nicotinamide adenine dinucleotide; HDACi, HDAC inhibitors

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2010 سفارش ترجمه

Basic-Liver, Pancreas, and Biliary TractFunctional Switching of TGF-β1 Signaling in Liver Cancer via Epigenetic Modulation of a Single CpG Site in TTP Promoter

Keywords: TTP; TGF-β1; Methylation; HCC; ARE; AU-rich element; AzadC; 5-azadeoxycytidine; ChIP; chromatin immunoprecipitation; DNMT; DNA methyltransferases; HCC; hepatocellular carcinoma; HDAC; histone deacetylase; mRNA; messenger RNA; PCR; polymerase chain reacti

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2010 سفارش ترجمه

Isoxazole moiety in the linker region of HDAC inhibitors adjacent to the Zn-chelating group: Effects on HDAC biology and antiproliferative activity

Keywords: HDAC; Pancreatic cancer; HDAC inhibitor; Isoform

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Design and synthesis of novel hybrid benzamide–peptide histone deacetylase inhibitors

Keywords: HDAC; Cyclic tetrapeptide; Solid-phase peptide synthesis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Huntington disease: pathogenesis, biomarkers, and approaches to experimental therapeutics

Keywords: huntingtin; MRI; Coenzyme Q10; striatum; BDNF; Rhes; HDAC; TRACK-HD; PREDICT-HD; PHAROS

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation

Keywords: HDAC; SAHA; Oxidation; NO; EPR; Free radicals

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Impact of drug discovery on stem cell biology

Keywords: GSK-3, glycogen synthase kinase-3; ROCK, rho-associated kinase; PI3-K, phosphatidylinositol 3-kinase; MEK, mitogen-activated protein kinase; PDE4, phosphodiesterase 4; p38 MAPK, p38 mitogen-activated protein kinase; ALK, activin receptor-like kinase; HDAC

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه