دانلود مقالات ISI درباره Hdac + ترجمه فارسی

Edible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes

Keywords: apoE−/−; apolipoprotein E knock out; BGA; blue-green algae; BMM; bone marrow-derived macrophages; CBP; CREB-binding protein; CREB; cAMP-response element-binding protein; C-PC; C-phycocyanin; CVD; cardiovascular disease; HAT; histone acetyltransferase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Reactivation of latent HIV by histone deacetylase inhibitors

Keywords: HIV; latency; HDAC; HDAC inhibitors

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic regulation of the innate immune response to LPS in bovine peripheral blood mononuclear cells (PBMC)

Keywords: Acetylation; Bovine; Innate immunity; Trichostatin A; HDAC; DNMT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

LC–MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma

Keywords: HDAC; Belinostat; Tandem mass spectrometry; Metabolites; Assay; Validation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Metabolic reprogramming by class I and II histone deacetylases

Keywords: HDAC; HAT; lipogenesis; gluconeogenesis; AMPK; HDAC3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Largazole, a class I histone deacetylase inhibitor, enhances TNF-α-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts

Keywords: HDAC; Rheumatoid arthritis; Synovial fibroblasts; ICAM-1; VCAM-1; Angiogenesis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors

Keywords: HDAC; BDNF; SAHA; MS-275; MC1568; CRE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation

Keywords: EGCG; epigallocatechin gallate; SFN; sulforaphane; PARP; poly(ADP-ribose) polymerase; HDAC; histone deacetylase; DMSO; dimethyl sulfoxide; DNMT1; DNA methyltransferase 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PI; propidium iod

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair

Keywords: 8-oxoG; 8-oxo-7,8-dihydroguanine; Ac; acetylated; AcOgg1; acetylated 8-oxoguanine DNA glycosylase-1; AP; abasic; APE1; apurinic apyrimidinic endonuclease1; BER; base excision repair; BrdU; 5-bromo-2′-deoxyuridine; DNPH; 4-dinitrophenylhydrazine; ERK; ex

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Linear and cyclic glycopeptide as HIV protease inhibitors

Keywords: HIV-1 protease; Linear and cyclic glycopeptides; Solid and solution peptide synthesis; Molecular docking; AIDS; acquired immunodeficiency syndrome; CTC; 2-chlorotrityl chloride; DCM; dichloromethane; DIPEA; N,N-diisopropyl ethylamine; DMF; N,N-dimethylfor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regulate the NY-ESO1 gene expression

Keywords: Dnmt; Epigenetic; HDAC; NY-ESO1; Glioma; Mesothelioma

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Unique functional roles for class I and class II histone deacetylases in central nervous system development and function

Keywords: Epigenetic; HDAC; Synaptic function; Learning; LTP

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

SIRT1 activation protects against autoimmune T cell-driven retinal disease in mice via inhibition of IL-2/Stat5 signaling

Keywords: HDAC; SIRT1; EAU; Uveitis; Behçet's; STAT5A/BEAU, Experimental autoimmune uveoretinitis; IRBP, Interphotoreceptor retinoid-binding protein; MDSC, Myeloid derived suppressor cells; HAT, Histone acetyl transferase; HDAC, Histone deacetylase; OBD, Ocular Beh

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation

Keywords: TH2 responses; IL-4; dendritic cells; monocyte-derived dendritic cells; house dust mite-induced allergic reactions; AAMΦ; Alternatively activated macrophage; BMDC; Bone marrow-derived dendritic cell; BMMΦ; Bone marrow macrophage; cDC; Conventional d

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2013 سفارش ترجمه

Vitamin D in thyroid tumorigenesis and development

Keywords: 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 25-OHD3; 25-hydroxyvitamin D3; ATC; anaplastic thyroid cancer; CDK; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; CEA; carcinoembryogenic antigen; CT; calcitonin; CYP24A1; 24-hydroxylase; CYP27B

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2013 سفارش ترجمه

Spermidine inhibits MMP-2 via modulation of histone acetyltransferase and histone deacetylase in HDFs

Keywords: Spermidine; MMP-2; HAT; HDAC; NF-κB; HDFs;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Valproate induces epigenetic modifications in lymphomonocytes from epileptic patients

Keywords: CNS; central nervous system; GABA; gamma-aminobutyric acid; GAD; glutamic acid decarboxylase; H3; histone 3; HDAC; histone deacetylase; PBMC; peripheral blood mononuclear cells; TSA; trichostatin-A; VPA; valproate; DNA methylation; Epimutations; Histone a

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei

Keywords: HAT; human African trypanosomiasis; VSG; variant surface glycoprotein; HDAC; histone deacetylases; DAC; deacetylases; SAR; Structure-activity relationship; Anti-parasitic activity; Trypanosoma brucei; Histone deacetylase inhibitors; Hydroxamic acids;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylase (HDAC) inhibitors and regulation of TRAIL-induced apoptosis

Keywords: Apoptosis; HDAC; TRAIL;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Phase I Trial of Vorinostat Combined With Bortezomib for the Treatment of Relapsing and/or Refractory Multiple Myeloma

Keywords: Cell cycle; HDAC; HDAC inhibitor; Proteasome inhibitor; Suberoylanilide hydroxamic acid (SAHA); Synergistic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components

Keywords: Histone demethylases; LSD1; HDAC; Transcription; Inflammation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Acetylation of sphingosine kinase 1 regulates cell growth and cell-cycle progression

Keywords: Acetylation; Cell growth; Cell-cycle progression; Sphingosine kinase 1; acetyl-CoA; acetyl coenzyme A; Ad; adenovirus; CBP; CREB-binding protein; CREB; cAMP-response element-binding protein; EGFP; enhanced green fluorescent protein; FBS; fetal bovine seru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of polymorphisms in the porcine microRNA miR-1 locus on muscle fiber type composition and miR-1 expression

Keywords: bp; base pair; HDAC; histone deacetylase; MEF2; myocyte enhancer factor-2; miRNA; microRNA; pre-miRNA; precursor microRNA; pri-miRNA; primary microRNA; PCR; polymerase chain reaction; RFLP; restriction fragment length polymorphism; SNP; single nucleotide

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging

Keywords: ALDH2; aldehyde dehydrogenase 2; AMPK; adenosine monophosphate kinase; CREB; cyclic AMP response element binding protein; GNAT; Gcn5-related N-acetyltransferase; HAT; histone acetyltransferase; HDAC; histone deacetylase; LCAD; long chain acetyl-CoA dehydr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

ATP-binding cassette transporter A1 and HDL metabolism: effects of fatty acids

Keywords: ApoA-I; apolipoprotein A-I; ABCA1; ATP-binding cassette transporter A1; CETP; cholesterol ester transfer protein; CHD; coronary heart disease; EPA; eicosapentaenoic acid; HDAC; histone deacetylase; HDL; high-density lipoprotein; HDL-C; HDL cholesterol; LC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Identification and validation of bioactive small molecule target through phenotypic screening

Keywords: ADME; absorption, distribution, metabolism, and excretion; CsA; cyclosporin A; HBC; 4-[3,5-bis-[2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-4,5-dihydro-pyrazol-1-yl]-benzoic acid; HDAC; histone deacetylase; HUVEC; human umbilical vascular endothelial cell; KF;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

ABCA1, ABCG1, and SR-BI: Transit of HDL-associated sphingosine-1-phosphate

Keywords: S1P; sphingosine-1-phosphate; HDL-S1P; HDL-associated S1P; ABCA1; ATP-binding cassette transporter A1; SR-BI; scavenger receptor class B memberI; C1P; ceramide-1-phosphate; HDAC; histone deacetylases; TRAF2; TNF receptor-associated factor 2; SPHK; sphingo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Imidazo–benzothiazoles a potent microRNA modulator involved in cell proliferation

Keywords: miRNAs, microRNAs; RISC, RNA induced silencing complex; UTR, untranslated region; siRNAs, small interfering RNAs; HDACs, histone deacetylases; DIAP1, Drosophila inhibitor of apoptosis1MicroRNA; HDAC; Bantam; Imidazo–benzothiazoles; Colon cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic and Epigenetic Biomarkers of Colorectal Cancer

Keywords: Colon Cancer; Mutation; Epimutation; Methylation; 5-FU; 5-fluorouracil; APC; adenomatous polyposis coli; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; DNMT; DNA methyltransferases; EGFR; epidermal growth fact

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A fluorescent screening platform for the rapid evaluation of chemicals in cellular reprogramming

Keywords: CDy1; compound of designation yellow 1; HDAC; histone deacetylase; MEF; mouse embryonic fibroblast; LIF; leukemia inhibitory factor; 5′-azaC; 5′-azacytidine; TSA; trichostatin A.;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging Therapies in Hematopoietic Stem Cell Transplantation

Keywords: Allogeneic; Proteasome; Bortezomib; HDAC; Hypomethylating agent; Azacytidine; Review

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Acetylation of histone H3 prevents resistance development caused by chronic mTOR inhibition in renal cell carcinoma cells

Keywords: Renal cell carcinoma; HDAC; RAD001; Resistance development; Histone H3 acetylation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleThe therapeutic effect of histone deacetylase inhibitor PCI-24781 on gallbladder carcinoma in BK5.erbB2 mice

Keywords: GBCa; gallbladder carcinoma; HDAC; histone deacetylase; EGFR; epidermal growth factor receptor; BTC; biliary tract cancer; BK5; bovine keratin 5; BrdU; bromodeoxyuridine; USBM; ultrasound biomicroscopy; TUNEL; terminal deoxynucleotidyl transferase dUTP ni

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

ReviewAn updated view on stem cell differentiation into smooth muscle cells

Keywords: Stem cells; Smooth muscle cells; ROS; HDAC; Chromatin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleCombination therapy for hepatocellular carcinoma: Additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib

Keywords: BCLC; Barcelona Clinic Liver Cancer; CI; confidence interval; FACS; fluorescent-activated cell sorting; HCC; hepatocellular carcinoma; HBV; hepatitis B virus; HCV; hepatitis C virus; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitor; HSP90;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

SnoN oncoprotein enhances estrogen receptor-α transcriptional activity

Keywords: ChIP; chromatin immunoprecipitation; ER; estrogen receptor; ERE; estrogen response element; E2; 17-β-estradiol; HA; hemagglutinin; HDAC; histone deacetylases; NBD; nuclear receptor binding domain; SnoN; ski-related novel gene; TGF-ß; transforming growth

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT2 interferes with autophagy-mediated degradation of protein aggregates in neuronal cells under proteasome inhibition

Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; BSA; bovine serum albumin; CMA; chaperone-mediated autophagy; DMEM; Dulbecco's modified eagle's medium; ECL; enhanced chemiluminescence; FBS; fetal bovine serum; HD; Huntington's disease; HDAC; histone d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Redox modification of cell signaling in the cardiovascular system

Keywords: AngII; angiotensin II; ASK1; apoptosis signal-regulating kinase 1; BDNF; brain-derived neurotrophic factor; BH4; tetrahydrobiopterin; CaMKII; Ca2+/calmodulin-dependent protein kinase II; cGMP; cyclic guanosine monophosphate; ETC; electron transport chain;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Can we improve outcomes in patients with acute myelogenous leukemia? Incorporating HDAC inhibitors into front-line therapy

Keywords: acute myelogenous leukemia; AML; histone deacetylase inhibitors; HDAC; treatment; vorinostat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The HAT/HDAC interplay: Multilevel control of STAT signaling

Keywords: STAT; Acetylation; HDAC; HAT; Signal transduction; Transcriptional regulation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The role of classical and non-classical HLA class I antigens in human tumors

Keywords: APM; antigen processing machinery; β2-m; β2-microglobulin; CALR; calreticulin; CANX; calnexin; CTL; cytotoxic T lymphocyte; DAC; 5-aza-2′-deoxycytidine; ER; endoplasmic reticulum; ERAP; ER aminopeptidase associated with antigen processing; HC; heavy c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Chromatin as an oxygen sensor and active player in the hypoxia response

Keywords: HIF; Hypoxia inducible factor; ARNT; Aryl hydrocarbon nuclear translocator; VHL; von Hippel Lindau; PHD; Prolyl-hydroxylase; FIH; Factor inhibiting HIF; ChIP; Chromatin immunoprecipitation; SWI/SNF; Switch/Sucrose NonFermentable; ISWI; Imitation switch; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Computational identification of novel histone deacetylase inhibitors by docking based QSAR

Keywords: HDAC; Anti-cancer; Benzimidazole and imidazole inhibitors; Pharmacophore; 3D–QSAR; Virtual screening; Docking

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Valproic acid increases white matter repair and neurogenesis after stroke

Keywords: BSA; bovine serum albumin; BrdU; bromodeoxyuridine; CNPase; 2″,3″-cyclic nucleotide 3′-phosphodiesterase; DAPI; 4′,6′-diamidino-2-phenylindole; DCX; doublecortin; GFAP; glial fibrillary acidic protein; GLT1; glutamate transporter 1; HDAC; histon

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Valproic acid mediates the synaptic excitatory/inhibitory balance through astrocytes - A preliminary study

Keywords: BDNF; brain derived neurotrophic factor; CAM; cell adhesion molecules; E/I; excitatory/inhibitory; EAAT2; excitatory amino acid transporter 2; ECM; extracellular matrix; GDNF; glial derived neurotrophic factor; GSK; glycogen synthase kinase; HDAC; histone

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Nuclear hormone receptor co-repressors: Structure and function

Keywords: HDAC; histone deacetylase; HID; histone interaction domain; LBD; ligand binding domain; ID; interaction domain; RRM; RNA recognition motif; Nuclear receptor; Co-repressor; SMRT/NCoR; TBL1; GPS2; HDAC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylases are required for amphibian tail and limb regeneration but not development

Keywords: HDAC, histone deacetylase; VPA, valproic acid; NaBu, sodium butyrate; MMR, Marc’s modified ringers; RI, regeneration index; RS, mean regeneration score; hpa, hours post amputationXenopus laevis; Ambystoma mexicanum; HDAC; Regeneration; Epigenetic reprogra

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment

Keywords: HDAC; histone deacetylase; IMS; infant maternal separation; SFR; standard facility reared; EPM; Elevated Plus Maze; FST; Forced Swim Test; Early life stress; Mouse; Adolescent development; Frontal cortex; Histone deacetylases; Histone H4 acetylation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Retinoid metabolism and its effects on the vasculature

Keywords: ADH; alcohol dehydrogenase; ADMA; asymmetric dimethylarginine; AP-1; activated protein-1; apo14; β-apo-14′-carotenal; ARVM; adult rat ventricular myocytes; ATBC; Alpha-tocopherol Beta-carotene Cancer Prevention Study; atRA; all-trans retinoic acid; BCO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Valproic acid induces the glutamate transporter excitatory amino acid transporter-3 in human oligodendroglioma cells

Keywords: DHK; dihydrokainate; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DTT; 1,4-dithiothreitol; EAAC1; excitatory amino acid carrier 1; EBSS; Earle's balanced salt solution; EAAT1-2-3; excitatory amino acid transporter 1-2-3; FBS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه