Keywords: β-gal; beta-galactosidase; BPH; Blood Pressure High; BPL; Blood Pressure Low; BPN; Blood Pressure Normal; ChIP; chromatin immunoprecipitation; Cth; cystathionine γ-lyase; EH; essential hypertension; EMSA; electrophoretic mobility shift assay; HEK-293; h
مقالات ISI (ترجمه نشده)
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Keywords: African swine fever virus; Vaccine development; Reverse vaccinology; Recombinant protein expression; MVA; HEK-293;
Keywords: Kappa opioid receptor; Serotonin; Clearance; Serotonin transporter; Phosphorylation; Trafficking; 5-HT; 5-hydroxytryptamine (serotonin); Akt X; Akt inhibitor X (10-(4â²-(N-diethylamino)butyl)-2-chlorophenoxazine); Akt; protein kinase B/Akt; BNI; nor-bina
Keywords: Polyphenols; Antibiotics; Antioxidants; PACAP; Aβ; β-amyloid; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; CAT; catalase; CNS; central nervous system; COX-2; cyclooxyge
Keywords: Fluorescence; Fluoride; Living cells; Carbohydrazone; Triphenylamine; HEK-293;
Keywords: ESCs; embryonic stem cells; PEI; polyethylenimine; LF2K; Lipofectamine 2000â¢; GFP; green fluorescent protein; HEK-293; Thuman embryonic kidney 293T cells; Polyethylenimine; Mouse embryonic stem cells; Transfection;
Keywords: HEK-293F; FreeStyle⢠293-F; HEK-293; human embryonic kidney 293 cell line; CMV; cytomegalo virus; SVLT; the large T antigen of the SV40 virus; DoE; design of experiments; Medium; FreeStyle⢠293 expression medium; Optimem; opti-MEM® I reduced-serum me
Keywords: Andrographolide; C14 ester analogues; Epoxy diastereomers; Anti-cancer; HEK-293; MCF-7; Normal cells; ApoptosisAG, andrographolide; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DAPI, 4,6-diamidino-2-phenylindole; PARP, poly(ADP-ribos
Keywords: AAV; adeno-associated virus; Aex; ascites-derived exosomes; BACE1; beta secretase 1; BAP-TM; biotin acceptor peptide-transmembrane domain; CAM; cell adhesion molecule; CD; cluster of differentiation; CD; cytosine deaminase; Dex; dendritic cell-derived exo
Keywords: Antitubercular agent; Mycobacterium tuberculosis; Chalcone; Benzopyranone; Coumarin; HEK-293;
Identification of N-Hydroxycinnamamide analogues and their bio-evaluation against breast cancer cell lines
Keywords: Breast cancer; MDA-MB-231; MCF-7; N-Hydroxycinnamamide; HEK-293;
Evaluation of ODE-Bn-PMEG, an acyclic nucleoside phosphonate prodrug, as an antiviral against productive HPV infection in 3D organotypic epithelial cultures
Keywords: PMEG; 9-[(2-phosphonomethoxy)ethyl]guanine; ODE-Bn-PMEG; Octadecycloxyethyl benzyl 9-[(2-phosphonomethoxy)ethyl]guanine; HPMPC; (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, also known as Cidofovir (CDV); HPV; human papillomavirus; HR; high-risk; L
Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease
Keywords: ACN; Acetonitrile; AD; Alzheimer's disease; AMF; ammonium formate; ATP; adenosine-triphosphate; BzATP; 3â²-O-(4-Benzoyl)benzoyl ATP, strong agonist for P2X7 receptor; CNS; central nervous system; DMEM; Dulbecco's Modified Eagle's Medium; DMF; dimethylfor
Spontaneous activity, singly bound states and the impact of alpha1Phe64 mutation on GABAAR gating in the novel kinetic model based on the single-channel recordings
Keywords: GABAA receptor; γ-aminobutyric acid; Single-channel recordings; Kinetic model; Intermediate states; Spontaneous activity; AChR(s); acetylcholine receptor(s); ALA; α1F64Aβ2γ2 mutant(s), α1Phe64Alaβ2γ2 mutant(s); cDNA; complementary deoxyribonucleic
Comparison of two Jatropha species (Euphorbiaceae) used popularly to treat snakebites in Northeastern Brazil: Chemical profile, inhibitory activity against Bothrops erythromelas venom and antibacterial activity
Keywords: AEJg; aqueous extract of Jatropha gossypiifolia; AEJm; aqueous extract of Jatropha mollissima; ATCC; American type culture collection; ANOVA; analysis of variance; AUC0-120Â min; area under the time-course curves after 120Â min; BeV; Bothrops erythromel
The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target
Keywords: Aak2; 5â²AMP-activated protein kinase catalytic subunit alpha-2; ACC; acetyl CoA carboxylase; Acly; ATP citrate lyase; Adipo-IR; adipose tissue insulin resistance index; ADME; absorption, distribution, metabolism, excretion; AGA; appropriate-for-gestatio
Potential bactericidal activity of S. nux-vomica-ZnO nanocomposite against multidrug-resistant bacterial pathogens and wound-healing properties
Keywords: AFM; atomic force microscopy; ANOVA; analysis of Variance; ATCC; American type culture collection; BSA; bovine serum albumin; CAMHB; cation adjusted mueller hinton broth; CLSI; clinical and Laboratory Standards Institute; DFI; diabetic foot infections; DF
Cigarette smoke condensate alters Saccharomyces cerevisiae efflux transporter mRNA and activity and increases caffeine toxicity
Keywords: ABC transporter; Pdr5; Snq2; Cigarette smoke; Caffeine; Saccharomyces cerevisiae; ABC; ATP-binding cassette; AαC; 2-amino-9H-pyrido[23-b]indole; 4- ABP; 4-aminobiphenyl; BaP; benzo(a)pyrene; BLAST; Basic local alignment search tool; BCRP; breast cancer r
Functional genetic variants in the SIRT5 gene promoter in acute myocardial infarction
Keywords: AMI; acute myocardial infarction; CAD; coronary artery disease; CEBPB; CCAAT/enhancer binding protein β; DSVs; DNA sequence variants; EMSA; electrophoretic mobility shift assay; FOXC1; forkhead box C1; H9c2; rat cardiomyocyte line; HEK-293; human embryon
Physicochemical properties of cationic nanoemulsions and liposomes obtained by microfluidization complexed with a single plasmid or along with an oligonucleotide: Implications for CRISPR/Cas technology
Keywords: Nanoemulsion; Liposome; Co-complexation; CRISPR/Cas9; Microfluidization; Plasmid and oligonucleotide; ATCC/USA; American Type Culture Collection/USA; CRISPR/Cas; clustered regularly interspaced short palindromic repeats/CRISPR associated protein; DMEM; Du
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
Keywords: ANOVA; analysis of variance; BAPTA; 1,2-bis(o-aminophenoxy)ethane-N,N,N9,N9-tetraacetic acid; DA; dopamine; DMSO; dimethylsulfoxide; MBS; Barth's solution; nAChR; nicotinic acetylcholine receptor; α1-GLYRs; α1-glycine receptor; ROS; radical oxygen spe
ST2 from rainbow trout quenches TLR signalling, localises at the nuclear membrane and allows the nuclear translocation of MYD88
Keywords: CHSE-214; Evolution; HEK-293; Interleukin 1 receptor-like 1; Oncorhynchus mykiss; Toll-like receptor signalling; TIR-domain;
Subcellular distribution of the 18Â kDa translocator protein and transcript variant PBR-S in human cells
Keywords: 4E-T; eukaryotic translation initiation factor 4E nuclear import factor 1; BJ; human fibroblast cells; cDNA; DNA complementary to RNA; DCP1A; decapping mRNA 1A; DMEM; Dulbecco's modified Eagle's medium; eIF3η; eukaryotic translation initiation factor 3 s
Hemagglutinin and neuraminidase containing virus-like particles produced in HEK-293 suspension culture: An effective influenza vaccine candidate
Keywords: Influenza vaccine; Virus-like particles; Stable cell line; HEK-293; Quantification; Bioreactor production; Tangential flow filtration;
Detection of replication competent adenovirus upon serial passaging of recombinant adenovirus expressing FMDV capsid proteins
Keywords: HEK-293; Human adenovirus type 5; FMD virus; Replication competent adenovirus; PCR; Cell line bioassay;
Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling
Keywords: Breast cancer; Estrogen receptor; Phytoestrogen; Wedelolactone; AP-1; activator protein 1; CHFCS; charcoal stripped fetal bovine serum; CCND1; cyclin D1; CTSD; cathepsin D; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECL; enhan
PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene
Keywords: ARF6; ADP ribosylation factor 6; BAC; bacterial artificial chromosome; BLAST; basic local alignment search tool; BSAP; B-cell lineage specific activator protein; BTK; Bruton's tyrosine kinase; CD; cluster of differentiation; Cq; quantitative PCR cycle; CT
Early growth response-1 facilitates enterovirus 71 replication by direct binding to the viral genome RNA
Keywords: 3â²UTR; 3â²-untranslated region; 5â²UTR; 5â²-untranslated region; CNS; central nervous system; Co-IP; co-immunoprecipitation; CPE; cytopathogenic effect; DMEM; Dulbecco's modified Eagle's medium; EGR1; early growth response-1; eIF4E; eukaryotic initia
μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids
Keywords: MOR; μ-opioid receptor; 6TM MOR; six transmembrane helices μ-opioid receptor; 7TM MOR; seven transmembrane helices μ-opioid receptor; OIH; opioid induced hyperalgesia; VGCC; voltage-gated Ca2 + channels; cAMP; cyclic adenosine monophosphate; AC; adeny
PDE7A1 hydrolyzes cCMP
Keywords: A549; human lung carcinoma cell line; AMP; adenosine 5â²-monophosphate; cAMP; adenosine 3â²,5â²-cyclic monophosphate; B103; rat neuroblastoma cells; CMP; cytidine 5â²-monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; CyaA; Bordetella pertu
S-nitrosylation of TRIM72 at cysteine 144 is critical for protection against oxidation-induced protein degradation and cell death
Keywords: BIAM; Biotin iodoacetamide; DMEM; Dulbecco's modified eagle medium; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; GFP; Green fluorescent protein; GSNO; S-nitrosoglutathione; HEK-293; Homo sapiens embryonic kidney; H2O2; Hydrogen peroxide; IPC; Ischemic
SIRT4 inhibits cigarette smoke extracts-induced mononuclear cell adhesion to human pulmonary microvascular endothelial cells via regulating NF-κB activity
Keywords: COPD; chronic obstructive pulmonary disease; CS; cigarette smoking; CSE; cigarette smoking extracts; VCAM-1; vascular cell adhesion molecule-1; HPMECs; human pulmonary microvascular endothelial cells; FBS; fetal bovine serum; Ad-SIRT4; adenoviral SIRT4; H
Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling
Keywords: GPCR; G protein-coupled receptors; A1AR; A1 adenosine receptor; β1R & β2R; β-adrenergic receptor subtypes; HEK-293; human embryonic kidney cells; IP; immunoprecipitation; IB; immunoblotting; IF; immunofluorescence; cAMP; cyclic adenosine monophosphate;
Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells
Keywords: HEK-293; CHO-DG44; Transient gene expression; Transfection; Recombinant protein; Polyethylenimine; Suspension culture; Orbital shaking; Mammalian cells;
KCC2 transport activity requires the highly conserved L675 in the C-terminal β1 strand
Keywords: Chloride homeostasis; Inhibitory synapse; Regulation; HEK-293; Cation-chloride cotransporter; Evolution
Efficacy of tetracycline encapsulated O-carboxymethyl chitosan nanoparticles against intracellular infections of Staphylococcus aureus
Keywords: Nps; nanoparticles; O-CMC; o-carboxymethyl chitosan; Tet; tetracycline; Tet-O-CMC Nps; tetracycline loaded-O-carboxymethyl chitosan nanoparticles; Rod123; Rhodamine-123; WGA-AF; wheat germ agglutinin-Alexa fluor; SA113; Staphylococcus aureus 113 (specific
Intracerebral delivery of small interfering RNAs (siRNAs) using adenoviral vector protects mice against lethal peripheral rabies challenge
Keywords: Ad; adenovirus; BHK-21; baby hamster kidney-21; CNS; central nervous system; CVS-11; challenge virus standard-11; EGFP; enhanced green fluorescent protein; ffu; fluorescent foci unit; HEK-293; human embryonic kidney-293; L; large polymerase; LD50; lethal
Synthesis, characterization and cytotoxicity studies of methoxy alkyl substituted metallocenes
Keywords: Titanocene compounds; Antitumoral; Cytotoxicity; MCF-7; HEK-293; J774.A1;
RNA-driven genetic changes in bacteria and in human cells
Keywords: RNA; RNA-driven genetic modification; Oligonucleotides; Escherichia coli; HEK-293; Gene targeting
Pharmacophore-based discovery of FXR-agonists. Part II: Identification of bioactive triterpenes from Ganoderma lucidum
Keywords: AAJIHHYEPHRIET-XEFAKFPISA-N; DNVPQKQSNYMLRS-AWYZMFRDSA-N; AZPOACUDFJKUHJ-KRDQJDFUSA-N; LVGCWXNRZNCAJG-AMKDLFIQSA-N; SNZQBBATMLGADX-VVUVUVSISA-N; KASALCUNLBTNAA-LIPCCPSCSA-N; JVGJXXNUVVQEIG-MCKXIFHVSA-N; INIPQDKLXQHEAJ-NCQSLMINSA-N; YTVGSCZIHGRVAV-YQKBFJOX
Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation
Keywords: TUOXXRMLFZBSTB-UHFFFAOYSA-N; JTRRVYQZHXAOGI-UHFFFAOYSA-N; QMDSMBFIKFKGBD-MDZDMXLPSA-N; WPHVYHBQJIXGIJ-UHFFFAOYSA-N; FCSGTZIUJUNGAC-UHFFFAOYSA-N; GKTSXRHLYUJTSU-QHCPKHFHSA-N; SPFSVEKWCKWVLI-DEOSSOPVSA-N; SUHGVDRUULOBLM-ZXVVBBHZSA-N; CPEYWROBUIDLPI-UHFFFAOY
Utility of human embryonic kidney cell line HEK-293 for rapid isolation of fixed and street rabies viruses: comparison with Neuro-2a and BHK-21 cell lines
Keywords: Rabies; Rabies diagnosis; Virus isolation; Fixed rabies virus; Street rabies virus; HEK-293
Synthesis and cytotoxic activities of group 3 metal complexes having monoanionic tridentate ligands
Keywords: Metal complexes; Cytotoxic activity; C6; HEK-293; WHEI-164
The vesicle-trafficking protein munc18b increases the secretory capacity of mammalian cells
Keywords: Exocytosis; Gene therapy; HEK-293; HeLa; HT-1080; Lentiviral particles; Munc18b; SAMY; SEAP; Sec1/Munc18 proteins; Secretion engineering; Vesicle trafficking
Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist
Keywords: antipsychotic; anxiolytic; dopamine receptor; glycogen; 8-OH-DPAT; serotonin receptor; HEK-293; human embryonic kidney 293; JB-788; 8-{4-[(6-Methoxy-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-3-ylmethyl)-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione hydroch
Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing
Keywords: Influenza virus; HEK-293; Suspension culture; Serum-free medium; Bioreactor; Vaccine production;
C-tail mediated modulation of somatostatin receptor type-4 homo- and heterodimerizations and signaling
Keywords: cAMP; cyclic adenosine monophosphate; Co-IP; co-immunoprecipitation; D and A; donor and acceptor; D-PBS; Dulbecco's phosphate buffered saline; ERKs; extracellular signal-regulated kinases; FSK; forskolin; GPCRs; G-protein coupled receptors; hSSTR; human s
Enhancement of odorant detection sensitivity by the expression of odorant-binding protein
Keywords: Odorant-binding protein; Olfactory receptor I7; HEK-293; Olfactory receptor-based olfactory biosensor
Ethanol potentiates dopamine uptake and increases cell surface distribution of dopamine transporters expressed in SK-N-SH and HEK-293 cells
Keywords: Dopamine transporter; Ethanol; HEK-293; SK-N-SH; Dopamine uptake; Cell surface;
Studies on the protective immunity of Schistosoma japonicum bivalent DNA vaccine encoding Sj23 and Sj14
Keywords: Sj14; Sj23; Bivalent DNA vaccine; Protective immunity; Optimal immunization; DNA; deoxyribonucleic acid; PCR; polymerase chain reaction; SOE; splicing by overlap extention; HEK-293; human embryo kidney-293; RT-PCR; reverse transcriptase- polymerase chain