دانلود مقالات ISI درباره Hek293 + ترجمه فارسی

High level over-expression of different NCX isoforms in HEK293 cell lines and primary neuronal cultures is protective following oxygen glucose deprivation

Keywords: Sodium–calcium exchanger; Calcium homeostasis; Cerebral ischaemia; Over-expression; Neurons; HEK293; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Phenylalanine 368 of multidrug resistance-associated protein 4 (MRP4/ABCC4) plays a crucial role in substrate-specific transport activity

Keywords: MRP; multidrug resistance-associated protein; eYFP; enhanced yellow fluorescent protein; HEK293; human embryonic kidney 293 cells; DMEM; Dulbecco Eagle's modified medium; F368/Phe368; phenylalanine at position 368 of MRP4; W995/Trp995; tryptophan at posit

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A novel role for P2X7 receptor signalling in the survival of mouse embryonic stem cells

Keywords: ES; embryonic stem; m; mouse; HEK293; human embryonic kidney 293; Ion channel; ATP; Stem cell; Receptor; Survival; P2X receptor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The clustered protocadherins Pcdhα and Pcdhγ form a heteromeric complex in zebrafish

Keywords: BSA; bovine serum albumin; CLB; cell lysis buffer; dpf; days post-fertilization; EC; ectodomain; EDTA; ethylenediaminetetraacetic acid; GST; glutathione S-transferase; GFP; green fluorescent protein; hb; hindbrain; HEK293; human embryonic kidney; HRP; hor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein

Keywords: 17-N-Allylamino-17-demethoxygeldanamycin (17-AAG):GABAA receptor-protein-like 1 (GABARAPL1); Glandular epithelial cell 1 (GEC1); Heat shock protein 90 (HSP90); Michigan cancer foundation-7 (MCF-7); Proteasome inhibitors; 17-AAG; 17-N-Allylamino-17-demetho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Extracellular cysteine (Cys)/cystine (CySS) redox regulates metabotropic glutamate receptor 5 activity

Keywords: Extracellular cysteine (Cys)/cystine (CySS); Metabotropic glutamate receptor 5; Parkinson's disease; AMS; 4-Acetamide-4′-maleimidylstilbene-2,2′-disulfonic acid, disodium salt; BCA; Bradford Protein Assay; CRD; cysteine-rich domain; Cys; cysteine; C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation

Keywords: Ab; antibody; GK; glucokinase; GKRP; glucokinase regulatory protein; Glc; α-d-glucose; HEK293; human embryonic kidney 293 cells; hGK; human glucokinase; MIN6; mouse insulinoma cell; MODY; maturity-onset diabetes of the young; PDB; protein data bank; PNS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Calcium phosphate embedded PLGA nanoparticles: A promising gene delivery vector with high gene loading and transfection efficiency

Keywords: CaPi-pDNA-PLGA-NPs; PLGA nanoparticle; Calcium phosphate; Plasmid DNA; HEK293

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Proteolytic cleavage of the disease-related lysosomal membrane glycoprotein CLN7

Keywords: BFA; brefeldin A; CHX; cycloheximide; Ctsb; cathepsin B; Ctsl; cathepsin L; DMEM; Dulbecco's minimal essential medium; endo H; endoglycosidase H; ER; endoplasmic reticulum; GFP; green fluorescent protein; HEK293; human embryonic kidney 293; HGSNAT; hepari

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner

Keywords: AC; adenylyl cyclase; Bmax; maximal binding capacity; BSA; bovine serum albumin; β2-AR; β2-adrenergic receptor; CA; [3H]-cAMP formed; CT; cytoplasmic tail; DA; dopamine; DMSO; dimethyl sulfoxide; EL3; third extracellular loop; EC50; effective concentrat

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Signalling pathway of goldfish melanin-concentrating hormone receptors 1 and 2

Keywords: cAMP; cyclic AMP; ERK1/2; extracellular signal-related kinase 1/2; gfMCHR; goldfish melanin-concentrating hormone receptor; HEK293; human embryonic kidney 293; MCH; melanin-concentrating hormone; MCHR1; MCH-1 receptor; MCHR2; MCH-2 receptor; PTX; pertussi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Transient gene expression in HEK293 and vero cells immobilised on microcarriers

Keywords: TGE; transient gene expression; PEI; polyethylenimine; r-proteins; recombinant proteins; CHO; Chinese hamster ovary cells; NS0; mouse myeloma cells; BHK; baby hamster kidney cells; HEK293; human embryo kidney; oriP; Epstein-Barr virus replication origin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Efficient expression screening of human membrane proteins in transiently transfected Human Embryonic Kidney 293S cells

Keywords: Human membrane proteins; Overexpression; HEK293; Transient transfection; FSEC; Detergent screening

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

A simplified polyethylenimine-mediated transfection process for large-scale and high-throughput applications

Keywords: Transfection; Suspension culture; Polyethylenimine; Serum-free; HEK293; EBNA1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor

Keywords: AC; adenylyl cyclase; BGH; bovine growth hormone; cAMP; Cyclic adenosine monophosphate; CB1; cannabinoid receptor subtype 1; CB2; cannabinoid receptor subtype 2; CNS; central nervous system; DTT; dithiothreitol; GPCR; G protein-coupled receptor; HA; influ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

ZAS3 accentuates transforming growth factor β signaling in epithelial cells

Keywords: ZAS3; TGFβ; Ski; SnoN; HEK293

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Generation and evaluation of mammalian secreted and membrane protein expression libraries for high-throughput target discovery

Keywords: High-throughput; 96-Well mammalian protein expression; HEK293; Secretome; Membrane proteins; ‘Tag after stop codon’; Receptor–ligand

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Vascular peroxidase-1 is rapidly secreted, circulates in plasma, and supports dityrosine cross-linking reactions

Keywords: VPO1; vascular peroxidase 1; MPO; myeloperoxidase; EPO; eosinophil peroxidase; LPO; lactoperoxidase; TPO; thyroid peroxidase; HEK293; human embryonic kidney 293 cell line; TMB; 3,5,5′-tetramethylbenzodine; SDS-PAGE; sodium dodecyl sulfate-polyacryla

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β2-adrenergic receptor

Keywords: β2-AR; β2-adrenergic receptor; Bmax; Binding maximum of the ligand for the receptor; COS-1; Monkey kidney cells; GPCRs; G protein-coupled receptors; HEK293; human embryonic kidney cells; [3H] DHA; tritium labeled dihydroalprenolol; Kd; equilibrium disso

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

A novel expression and purification system for the production of enzymatic and biologically active human granzyme B

Keywords: Ac-IEPD-pNA; N-acetyl-Ile-Glu-Pro-Asp-p-nitroanilide; bps; base pairs; ctrl; control; deglyc; deglycosylated; HEK293; human embryonic kidney cells; grB; granzyme B protein; GrB; granzyme B gene sequence; NANA; neuraminic acid; Granzyme B; Purification; En

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Monitoring lentiviral vector production kinetics using online permittivity measurements

Keywords: Lentiviral vector production; HEK293; Perfusion culture; Online monitoring; Permittivity measurements; Dielectric spectroscopy; Process Analytical Technology (PAT)

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1

Keywords: AMPK; AMP-activated protein kinase; HEK293; human embryo kidney 293 cells; IIS; insulin/insulin-like signaling; IRS; insulin receptor substrate; MAPK; mitogen activated protein kinase; PGC-1α; PPARγ general co-activator 1α; PI3K; phosphoinositide 3-kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Block of the hERG channel by bupivacaine: Electrophysiological and modeling insights towards stereochemical optimization

Keywords: Bupivacaine; Cardiotoxicity; Electrophysiology; hERG channel; Molecular docking; Stereoselectivity; AP; action potential; cLQTS; congenital long QT syndrome; diLQTS; drug-induced long QT syndrome; ECG; electrocardiogram; ES; extracellular solution; GB/SA;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

KChIP1 modulation of Kv4.3-mediated A-type K+ currents and repetitive firing in hippocampal interneurons

Keywords: CA1 hippocampus; inhibitory neurons; excitability; K+ channels; accessory proteins; ACSF; artificial cerebrospinal fluid; AHP; afterhyperpolarization; DMEM; Dulbelcco's modified Eagle's medium; DPPL; dipeptidyl-peptidase-like protein; ERK; extracellular s

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases

Keywords: ACE2; angiotensin-converting enzyme 2; ADP; adenosine diphosphate; AGE; advanced glycation end-products; APV; DL-2-amino-5-phosphonovaleric acid; AT1; angiotensin II type I receptor; Aβ25-35; β-amyloid; Bcl-2; B-cell leukemia/lymphoma-2; BKCa; large-con

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluating regulatory elements of human cytomegalovirus major immediate early gene for enhancing transgene expression levels in CHO K1 and HEK293 cells

Keywords: hCMV MIE; 1st Exon; Intron A; HEK293; CHO K1; Erythropoietin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

GDP-Capture Compound — A novel tool for the profiling of GTPases in pro- and eukaryotes by capture compound mass spectrometry (CCMS)

Keywords: Functional proteomics; Capture Compound Mass Spectrometry; GTP; GTPases; Hek293; LC–MS/MS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Heterologous functional expression system for odorant receptors

Keywords: Odorant receptor; Heterologous functional expression; HEK293; Calcium imaging; Gα; RTP; OR-S6

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of cellular genes critical to recombinant protein production using a Gaussia luciferase-based siRNA screening system

Keywords: CEBPG; CHO; HEK293; EPO; Monoclonal antibody; siRNA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Developmental NeuroscienceResearch PaperRor1-Ror2 complexes modulate synapse formation in hippocampal neurons

Keywords: Ror1; Ror2; synaptogenesis; siRNAs; antisense oligonucleotides; E16; embryonic day 16; HEK293; Human embryonic kidney; MEM; minimum essential medium; MUT; mutated; PBS; phosphate buffer saline; RTKs; receptor tyrosine kinases; SCR; scrambled; siRNAs; smal

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of brain aquaporins

Keywords: ANP; atrial natriuretic peptide; AQP; aquaporin; ATP; adenosine triphosphate; BBB; blood-brain barrier; BSE; bovine spongiform encephalopathy; CaMKII; calcium/calmodulin dependent protein kinase II; cAMP; cyclic adenosine monophosphate; cGMP; cyclic gua

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2010 سفارش ترجمه

Effect of compound plate composition on measurement of hERG current IC50 using PatchXpress

Keywords: cLogP; Compound plate adsorption; HEK293; hERG; PatchXpress; Incubation time

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Identification and expression analysis of miRNAs during batch culture of HEK-293 cells

Keywords: microRNA (miRNA); HEK293; Batch cell culture; CHO

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells

Keywords: TRPC6; Podocytes; HEK293; Flufenamic acid; Calcium signalling

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Interaction of porphyrins with human organic anion transporting polypeptide 1B1

Keywords: BSP; bromosulfophthalein; HEK293; human embryonic kidney; ICG; indocyanine green; OATP1B1; organic anion transporting polypeptide 1B1; OATP1B1 inhibitor; Porphyria; Bilirubin; Porphyrin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice

Keywords: ROS; reactive oxygen species; SOD; superoxide dismutase; FALS; familial amyotrophic lateral sclerosis; GST; glutathione S-transferase; 4-HNE; 4-hydroxynonenal; CDNB; 1-chloro-2,4-dinitrobenzene; MDA; malondialdehyde; Fe-NTA; ferric nitrilotriacetate; HE

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Measurement of cellular β-site of APP cleaving enzyme 1 activity and its modulation in neuronal assay systems

Keywords: BACE1; Amyloid-β peptide (Aβ); APP; SEAP; CGC; HEK293

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Effects on capacitance by overexpression of membrane proteins

Keywords: Patch-clamp; Electrorotation; Freeze-fracture electron microscopy; HEK293; Overexpression; Membrane capacitance; Channelrhodopsin-2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells

Keywords: Iron; IRP2; HOIL-1; Ubiquitylation; Degradation; HEK293;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain

Keywords: TAK-242; Macrophage; LPS; TLR4; CD4-TLR4, NF-κB; HEK293

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

p120-catenin is a novel desmoglein 3 interacting partner: Identification of the p120-catenin association site of desmoglein 3

Keywords: AA; amino acid; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's Medium; DTD; desmoglein terminal domain; Dscs; desmocollins; Dsg; desmoglein; Dsgs; desmogleins; EA; extracellular anchor; EC; extracellular; FCS; fetal calf serum; HA; hemagglut

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Single cell transfection using plasmid decorated AFM probes

Keywords: Individual cell transfection; Atomic force microscopy; HEK293; EGFP; Membrane penetration

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Expression and significance of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-1 in an animal model of renal interstitial fibrosis induced by unilateral ureteral obstruction

Keywords: ADAMTS-1; Renal interstitial fibrosis; Unilateral ureteral obstruction; In situ hybridization; HEK293; NRK-49F; Thymidine uptake

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of tau phosphorylation on proteasome activity

Keywords: AD; Alzheimer's disease; NFT; neurofibrillary tangle; HEK293; human embryonic kidney cell; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide thiazolyl blue; BCA; bicinchoninic acid; PKA; protein kinase A; PP1; protein phosphotase 1; PP2A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Activation of muscarinic receptors reduces store-operated Ca2+ entry in HEK293 cells

Keywords: Acetylcholine; Ca2+ release-activated Ca2+ current; HEK293; ICRAC; Muscarinic receptor; SOCE; Store-operated Ca2+ entry

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Generation and application of a fluorescein-specific single chain antibody

Keywords: FITC; Single chain antibody; hCG; HEK293; Periplasmic expression; Phage display; Immunoassay;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells

Keywords: Adeno-associated virus; AAV; Transfection; PEI; Serum-free medium; Suspension cells; HEK293; Bioreactor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Histochemical evidence for wide expression of the metalloendopeptidase nardilysin in human brain neurons

Keywords: metalloendopeptidase; western blot analysis; cellular distribution; human brain; p42IP4; centaurin-α1; EDTA; ethylene diamine tetraacetate; GFAP; glial fibrillary acidic protein; HB-EGF; heparin-binding epidermal growth factor-like growth factor; HEK293;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of tyrosines in the putative regulatory site of the Ca2+ channel TRPV6

Keywords: HEK293; human embryonic kidney 293; PTP1B; tyrosine phosphatase 1B; DMHV; bis-(N,N-dimethyl-hydroxamido) hydroxo-vanadate; SOC; store operated Ca2+ channel; BiFC; bimolecular fluorescence complementation; PV; pervanadate; ROS; reactive oxygen species; GST

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Monad, a WD40 repeat protein, promotes apoptosis induced by TNF-α

Keywords: WD40; Apoptosis; Caspase; TNF-α; Monad; Apaf-1; Testis; HEK293; NF-κB

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه