Immune Interactions in Hepatic Fibrosis
Keywords: سلول ستاره ای کبدی; Liver; Inflammation; Stroma; Lymphocytes; Fibrosis; Hepatic stellate cell;
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Hepatic stellate cell damage may lead to decreased plasma ADAMTS13 activity in rats
Keywords: سلول ستاره ای کبدی; ADAMTS13; Hepatic stellate cell; Dimethylnitrosamine; Hepatectomy
Wnt signaling enhances the activation and survival of human hepatic stellate cells
Keywords: سلول ستاره ای کبدی; Hepatic stellate cell; Fibrosis; Wnt; Secreted frizzled-related protein 1; Apoptosis
Bile acid-mediated thrombospondin-1 induction in hepatocytes leads to transforming growth factor-β-dependent hepatic stellate cell activation
Keywords: سلول ستاره ای کبدی; Hepatic stellate cell; Bile acid; Transforming growth factor-β; Thrombospondin-1; CholestasisHSC, hepatic stellate cell; TGF-β, transforming growth factor-β; FXR, farnesoid X receptor; SHP, small heterodimer partner; Mcl-1, myeloid cell leukemia-1; TSP-1,
Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile duct-ligated rats
Keywords: سلول ستاره ای کبدی; Liver fibrosis; Drug targeting; Hepatic stellate cell; Selective delivery; Cytostatic drugs; Mannose-6-phosphate/insulin-like growth factor II receptor
Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts
Keywords: سلول ستاره ای کبدی; Bakuchiol; Hepatic stellate cell; Myofibroblast; Apoptosis; c-Jun NH2-terminal protein kinase
Effects and mechanisms of extract from Paeonia lactiflora and Astragalus membranaceus on liver fibrosis induced by carbon tetrachloride in rats
Keywords: سلول ستاره ای کبدی; Paeonia lactiflora; Astragalus membranaceus; Liver fibrosis; Oxidative stress; Transforming growth factor-β1; Hepatic stellate cell
Reversal Effect of Thalidomide on Established Hepatic Cirrhosis in Rats via Inhibition of Nuclear Factor-κB/Inhibitor of Nuclear Factor-κB Pathway
Keywords: سلول ستاره ای کبدی; Thalidomide; Cirrhosis; Adhesion molecule; Nuclear factor-κB; Inhibitor of nuclear factor-κB; Hepatic stellate cell
Significance and Therapeutic Potential of Endothelial Progenitor Cell Transplantation in a Cirrhotic Liver Rat Model
Keywords: سلول ستاره ای کبدی; α-SMA; α-smooth muscle actin; BM; bone marrow; CCl4; carbon tetrachloride; ECM; extracellular matrix; EGF; epithelial growth factor; EPC; endothelium progenitor cell; Flk-1; fetal liver kinase-1; Flt-1; fms-like tyrosine kinase-1; HGF; hepatocyte growth
Bile acid-mediated induction of cyclooxygenase-2 and Mcl-1 in hepatic stellate cells
Keywords: سلول ستاره ای کبدی; Hepatic stellate cell; Bile acid; Cyclooxygenase-2; Mcl-1; Apoptosis
Angiotensin-II and vascular endothelial growth factor interaction plays an important role in rat liver fibrosis development
Keywords: سلول ستاره ای کبدی; Angiogenesis; Angiotensin-II; Hepatic stellate cell; Liver fibrosis; VEGF;
Reversal of chemical-induced liver fibrosis in Wistar rats by puerarin
Keywords: سلول ستاره ای کبدی; Liver fibrosis; Puerarin; Alcohol; Carbon tetrachloride; Hepatic stellate cell; Apoptosis
Traditional Chinese medicine Bao Gan Ning increase phosphorylation of CREB in liver fibrosis in vivo and in vitro
Keywords: سلول ستاره ای کبدی; ALT, alanine aminotransferase; CRE, cAMP response element; CREB, cAMP response element binding protein; EMSA, electrophoretic mobility shift assay; PKA, protein kinase ATraditional Chinese medicine; Liver fibrosis; Hepatic stellate cell; CREB; Phosphoryla
Effects of rhDecorin on TGF-β1 induced human hepatic stellate cells LX-2 activation
Keywords: سلول ستاره ای کبدی; HSCs, hepatic stellate cells; TGF-β1, transforming growth factor-β1; ECM, extracellular matrix; MMP, metalloproteinase; TIMP, tissue inhibitor of metalloproteinase; α-SMA, smooth muscle-α-actinDecorin; Hepatic stellate cell; LX-2 cell line; Fibrogenesis;
The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-β in smooth muscle and hepatic stellate cells
Keywords: سلول ستاره ای کبدی; LIM domain proteins; Cysteine- and glycine-rich protein; Transforming growth factor-β; Gene regulation; Smooth muscle cell; Hepatic stellate cell; Bisulfite genomic analysis; Smad proteins
Mechanisms of liver fibrosis
Keywords: سلول ستاره ای کبدی; Hepatic stellate cell; Collagen; Extracellular matrix; Intracellular signaling; Matrix metalloproteinases; Transforming growth factor-β;
Anti-proliferative and pro-apoptotic effects of herbal medicine on hepatic stellate cell
Keywords: سلول ستاره ای کبدی; HSC; hepatic stellate cell; TUNEL; terminal transferase uridyl nick end labeling; AS; Angelica sinensis; AM; Astragalus membranaceus; CS; Cordyceps sinensis; CW; Curcuma wenyujin; CT; Carthamus tinctorius; CK; Curcuma kwangsinensis; BC; Bupleurum chinensi
Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells
Keywords: سلول ستاره ای کبدی; BrdU; 5-bromo-2â²-deoxy-uridine; DMEM; Dulbecco's modified Eagle medium; EDTA; ethylenediaminetetraacetate; EGCG; epigallocatechin-3-gallate; FAK; focal adhesion kinase; FCS; fetal-calf serum; GDP; guanosine diphosphate; GTP; guanosine triphosphate; HS
Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice
Keywords: سلول ستاره ای کبدی; Thioredoxin; Hepatic fibrosis; Stellate cell; ADF; adult T cell leukemia-derived factor; ALT; alanine aminotransferase; AP-1; activator protein-1; AST; aspartate aminotransferase; CHX; cycloheximide; DMEM; Dulbecco's modified eagle medium; EB; Epstein-B
Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation
Keywords: سلول ستاره ای کبدی; Alpha-SMAalpha smooth muscle actin; DL; donor livers; ECM; extra-cellular matrix; HAI; histology activity index; HBV-C; HBV cirrhosis; HCV-C; HCV cirrhosis; HCV-PTR; post-transplant HCV recurrent hepatitis; HSC; hepatic stellate cell; Hepatic stellate cel
Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-l-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells
Keywords: سلول ستاره ای کبدی; Hepatic stellate cell; PDGF; ROS; TGF-β; Signaling;
Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell
Keywords: سلول ستاره ای کبدی; Liver fibrosis; Hepatic stellate cell; Mycophenolic acid; Drug targeting; Proliferation of hepatic stellate cells; Activation of hepatic stellate cells; HSC; Hepatic Stellate Cell; MPA; Mycophenolic Acid; M6P-HSA; Mannose-6-phosphate modified human serum
Characterization of the human zinc finger protein 267 promoter: Essential role of nuclear factor Y
Keywords: سلول ستاره ای کبدی; HSCs; hepatic stellate cells; ZNF267; zinc finger protein 267; ECM; extracellular matrix; C/EBP; CCAAT/enhancer-binding protein; NF-Y; nuclear factor Y; KLF; Kruppel-like factor; KRAB; Kruppel associated box; MMP; matrix metalloproteinase; HEK; human embr
Cell Type-Specific Intervention of Transforming Growth Factor β/Smad Signaling Suppresses Collagen Gene Expression and Hepatic Fibrosis in Mice
Keywords: سلول ستاره ای کبدی; GFP; green fluorescent protein; HSC; hepatic stellate cell; IFN; interferon; TbRE; transforming growth factor β-responsive element; TGF; transforming growth factor; α-SMA; α-smooth muscle actin;
Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes
Keywords: سلول ستاره ای کبدی; Animal model; Antifibrotics; Bile duct; Collagen; Liver fibrosis; Knockout mice; PAI-1; PDGF receptor; Procollagen; PSC; TGF-β; TIMP-1; HSC; hepatic stellate cell; HYP; hydroxyproline; Mdr2; multidrug resistance protein 2/canalicular phospholipids export
Herbal medicine Rhei rhizome prevents liver fibrosis in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet
Keywords: سلول ستاره ای کبدی; Herbal medicine; Rhei rhizome; Fibrosis; Hepatic stellate cell
The plasticity of p19ARF null hepatic stellate cells and the dynamics of activation
Keywords: سلول ستاره ای کبدی; Hepatic stellate cell; TGF-β; Fibrogenesis; Myofibroblast;
Upregulation of pleiotrophin expression in rat hepatic stellate cells by PDGF and hypoxia: Implications for its role in experimental biliary liver fibrogenesis
Keywords: سلول ستاره ای کبدی; Pleiotrophin; Anaplastic lymphoma kinase; Heparin affin regulatory peptide; Hepatic stellate cell; Platelet derived growth factor; α-smooth muscle actin;
Connective Tissue Growth Factor (CCN2) in Rat Pancreatic Stellate Cell Function: Integrin α5β1 as a Novel CCN2 Receptor
Keywords: سلول ستاره ای کبدی; α-SMA; α-smooth muscle actin; BSA; bovine serum albumin; CCN2; connective tissue growth factor; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; FN; fibronectin; HRP; horseradish peroxidase; HSC; hepatic stellate cell; HSPG; heparan
Hepatitis C Virus-Replicating Hepatocytes Induce Fibrogenic Activation of Hepatic Stellate Cells
Keywords: سلول ستاره ای کبدی; CTGF; connective tissue growth factor; DMEM; Dulbecco's modified Eagle medium; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; HSC; hepatic stellate cell; MF; myofibroblastic cells; MMP; matrix metalloproteina
Bile acids induce hepatic stellate cell proliferation via activation of the epidermal growth factor receptor
Keywords: سلول ستاره ای کبدی; BrdU; bromodeoxyuridine; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; GCDCA; glycochenodeoxycholic acid; HSC; hepatic stellate cell; JNK; c-Jun N-terminal kinase; MEK; mitogen-activated
Cytokines and Peroxisome Proliferator-Activated Receptor γ Ligand Regulate Phagocytosis by Pancreatic Stellate Cells
Keywords: سلول ستاره ای کبدی; DMEM; Dulbecco's modified Eagle medium; ECM; extracellular matrix; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; GFAP; glial fibrillary acidic protein; HSC; hepatic stellate cell; IL; interleukin; oxLDL; oxidized low-density lipoprotein; PI;
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
Keywords: سلول ستاره ای کبدی; BrdU; bromodeoxyuridine; CC; carcinoma cell; DMEM; Dulbecco's modified Eagle medium; ECM; extracellular matrix; FCS; fetal calf serum; FGF; fibroblast growth factor; FITC; fluorescein isothiocyanate; HRP; horseradish peroxidase; HSC; hepatic stellate ce
Intercellular communication via gap junctions in activated rat hepatic stellate cells
Keywords: سلول ستاره ای کبدی; Cx; connexin; DMEM; Dulbecco's modified Eagle medium; ET-1; endothelin 1; FITC; fluorescein isothiocyanate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; HSC; hepatic stellate cell; IL; interleukin; KC; Kupffer