دانلود مقالات ISI درباره Hepg2 + ترجمه فارسی

Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways

Keywords: HepG2; human hepatoblastoma; ROS; reactive oxygen species; 3-MA; 3-methyladenine; RAP; rapamycin; NAC; NAcetyl-l-cysteine; PARP; poly (ADP-ribose) polymerase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MDC; Monodansylcadaverine; MM

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Phosphoramidate protides of five flavones and their antiproliferative activity against HepG2 and L-O2 cell lines

Keywords: Flavone; Phosphoramidate; HepG2; G2/M arrest; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of novel pyrazolo[1,5-a]pyrimidine derivatives bearing nitrogen mustard moiety and evaluation of their antitumor activity in vitro and in vivo

Keywords: Pyrazolo[1,5-a]pyrimidine; Nitrogen mustard derivatives; Anti-tumor; Cell cycle; Apoptosis; Xenograft mice model; MTT; (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; A549; human alveolar adenocarcinoma cell line; SH-SY5Y; human neuroblasto

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Magnolia officinalis (Hou Po) bark extract stimulates the Nrf2-pathway in hepatocytes and protects against oxidative stress

Keywords: ARE; antioxidant response element; GCLC; glutamate-cysteine ligase catalytic subunit; Hepa1c1c7; murine hepatoma cells; HepG2; human hepatoma cells; HMOX1; heme oxygenase-1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; Keap1; Kelch-like ECH-associated

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells

Keywords: Hepcidin; Iron; HepG2; Hepatocyte; Transferrin;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Mitophagy inhibits proliferation by decreasing cyclooxygenase-2 (COX-2) in arsenic trioxide-treated HepG2 cells

Keywords: Proliferation; Mitophagy; Cyclooxygenase-2; Arsenic trioxide; HepG2;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Clausenidin from Clausena excavata induces apoptosis in hepG2 cells via the mitochondrial pathway

Keywords: RPMI; Rosewell Park Memorial Institute; HepG2; liver hepatocellular carcinoma; DNA; Deoxyribonucleic acid; DMSO; Dimethyl sulfoxide; JNK; c-Jun N-terminal kinases; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide; Apaf-1; Apoptotic protea

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells

Keywords: ALA; alpha-lipoic acid; ER stress; endoplasmic reticulum (ER) stress; HepG2; hepatoblastoma cell line; Tun; tunicamycin; OXPHOS; oxidative phosphorylation; Olig; oligomycin; T2DM; type 2 diabetes mellitus; IRS; insulin receptor substrate; PI3K; phosphatid

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

AkP from mushroom Termitomyces clypeatus is a proteoglycan specific protease with apoptotic effect on HepG2

Keywords: AkP; alkaline serine protease of T. clypeatus; HepG2; human hepatocellular carcinoma; L-02; human hepatocyte line; HSPG; heparan sulfate proteoglycan; IEF; isoelectric focusing; β-ME; β-mercaptoethanol; pI; isoelectric point; PMSF; phenyl methane sulfon

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological evaluation of PEGylated CuO nanoparticles

Keywords: NPs; nanoparticles; PEG 1000; polyethylene glycol 1000; PEG 8000; polyethylene glycol 8000; Cu NPs; copper nanoparticles; CuO; cupric oxide; HepG2; human hepatocellular carcinoma cells; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; RO

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Cytotoxic and genotoxic effects of ethanolic extract of Euphorbia hyssopifolia L. on HepG2 cells

Keywords: HepG2; human hepatoma cell culture; MTT assay; colorimetric MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay; CBMN assay; cytokinesis-block micronucleus assay; FBS; fetal bovine serum; DMSO; dimethyl sulfoxide; PBS; phosphate buffe

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

In-vitro assessment of cytotoxicity of halloysite nanotubes against HepG2, HCT116 and human peripheral blood lymphocytes

Keywords: Halloysite nanotubes; HepG2; HCT116; Peripheral blood lymphocytes; In-vitro cytotoxicity; Pharmaceutical excipients; Size distribution;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Investigation of the dominant positive effect of porcine farnesoid X receptor (FXR) splice variant 1

Keywords: CAR; constitutive androstane receptor; PXR; pregnane X receptor; FXR; farnesoid X receptor; CYP3A4; cytochrome P450 3A4; SULT2A1; hydroxysteroid sulfotransferase; UGT2B4; UDP-glucuronosyltransferase 2B4; GRβ; glucocorticoid receptor β; ERE; estrogen res

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Research PaperGrowth inhibition of human liver carcinoma HepG2 cells and α-glucosidase inhibitory activity of Murdannia bracteata (C.B. Clarke) Kuntze ex J.K. Morton extracts

Keywords: Murdannia bracteata; HepG2; Caspase-3; α-Glucosidase inhibitory activity; α-Tocopherol; Apigenin derivative;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatocellular carcinoma cells express 25(OH)D-1α-hydroxylase and are able to convert 25(OH)D to 1α,25(OH)2D, leading to the 25(OH)D-induced growth inhibition

Keywords: HCC; HepG2; CYP27B1; CYP24A1; 25-Hydroxyvitamin D; Gene therapy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells

Keywords: De-novo lipogenesis; VLDL; SH2 domain-containing inositol 5-phosphatase (SHIP2); Insulin resistance; HepG2; Liver; ACC; acyl COA carboxylase; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GFP; green fluorescent protein; MTP; microsomal transfe

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Irbesartan, an FDA approved drug for hypertension and diabetic nephropathy, is a potent inhibitor for hepatitis B virus entry by disturbing Na+-dependent taurocholate cotransporting polypeptide activity

Keywords: Irbesartan; Hepatitis B virus; Viral entry inhibitor; NTCP; HepG2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cytotoxicity, oxidative stress, and apoptosis in HepG2 cells induced by ionic liquid 1-methyl-3-octylimidazolium bromide

Keywords: Ionic liquids; HepG2; Cytotoxicity; Oxidative stress; Apoptosis; Caspase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Anticancer activity of Aloe vera and Calligonum comosum extracts separetely on hepatocellular carcinoma cells

Keywords: HepG2; Hepatocellular carcinoma; Aloe vera; Calligonum comosum; Apoptosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro inhibitory activities of six gypenosides on human liver cancer cell line HepG2 and possible role of HIF-1α pathway in them

Keywords: Gypenosides; Gynostemma pentaphyllum; Cytotoxic activity; HepG2; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Encapsulation of honokiol into self-assembled pectin nanoparticles for drug delivery to HepG2 cells

Keywords: Honokiol; Hydroxypropyl-β-cyclodextrin; Pectin; Nanoparticle; HepG2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cytotoxic, caspase-3 induction and in vivo hepatoprotective effects of phyllanthin, a major constituent of Phyllanthus niruri

Keywords: Phyllanthin; Phyllanthus niruri; Antiproliferation; HepG2; Apoptosis; Hepatoprotective effect;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The potentiation effect makes the difference: Non-toxic concentrations of ZnO nanoparticles enhance Cu nanoparticle toxicity in vitro

Keywords: ZnONPs; CuNPs; HepG2; Potentiation effect; Cytotoxicity assays;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

PRDX1 is involved in palmitate induced insulin resistance via regulating the activity of p38MAPK in HepG2 cells

Keywords: PRDX1; Insulin resistance; p38MAPK; HepG2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Phenolic compounds ameliorate the glucose uptake in HepG2 cells' insulin resistance via activating AMPK: Anti-diabetic effect of phenolic compounds in HepG2 cells

Keywords: Phenolics; HepG2; insulin resistance; AKT pathway; AMPK

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells

Keywords: PD; Platycodin D; CQ; chloroquine; DMSO; dimethylsulfoxide; MTT; 3-[4,5-Dimethyl-2-thiazolyl]-2,5-diphenyltetrazolium bromide; MDC; monodansylcadaverin; ERK; extracellular signal-regulated kinase; BAF; bafilomycin A1; LC3; microtubule-associated protein 1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The modulating effect of ATM, ATR, DNA-PK inhibitors on the cytotoxicity and genotoxicity of benzo[a]pyrene in human hepatocellular cancer cell line HepG2

Keywords: Benzo[a]pyrene; PIKK inhibitors; DNA damage signaling; HepG2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatitis C virus NS3 protein enhances cancer cell invasion by activating matrix metalloproteinase-9 and cyclooxygenase-2 through ERK/p38/NF-κB signal cascade

Keywords: AP-1; activation protein-1; CMA; cell matrix adhesion; COX-2; cyclooxygenase-2; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; HBV; hepatitis B v

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking

Keywords: Design; HepG2; Urea; VEGFR-2; DockingBWDUFTFGRLWGPS-UHFFFAOYSA-N; RJXKVRUPSNTEFX-UHFFFAOYSA-N; OKLQCYFQMONOPW-UHFFFAOYSA-N; DNZXILGNPOQNRU-UHFFFAOYSA-N; UVYSLYUGYAMGFT-UHFFFAOYSA-N; WJTWGCCKHAGBQI-UHFFFAOYSA-N; AFQLIQQRPCOQKP-UHFFFAOYSA-N; LVOLDCCULPVRSN-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: Potential role in liver fibrosis

Keywords: TNF; tumor necrosis factor; IL; interleukin; HepG2; liver hepatocellular carcinoma cell line; EDTA; ethylenediaminetetraacetic acid; DTT; dithiothreitol; NaCl; sodium chloride; NaF; sodium fluoride; ChIP; chromatin immunoprecipitation; qRT-PCR; quantitati

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Low concentrations of cylindrospermopsin induce increases of reactive oxygen species levels, metabolism and proliferation in human hepatoma cells (HepG2)

Keywords: Cyanotoxin; Cylindrospermopsin; Cell lineage; HepG2; CYPs

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of cyanobacterial endolith Leptolyngbya sp. ISTCY101, for integrated wastewater treatment and biodiesel production: A toxicological perspective

Keywords: Wastewater treatment; Endolith; Leptolyngbya sp. ISTCY101; Marble; Genotoxicity; HepG2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Compound Astragalus and Salvia miltiorrhiza extracts modulate MAPK-regulated TGF-β/Smad signaling in hepatocellular carcinoma by multi-target mechanism

Keywords: CASE; Hepatocellular carcinoma; HepG2; HSC; MAPK; TGF-β1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Hydroxyl metabolite of PCB 180 induces DNA damage signaling and enhances the DNA damaging effect of benzo[a]pyrene

Keywords: PCBs; polychlorinated biphenyls; PAHs; polycyclic aromatic hydrocarbons; BaP; benzo[a]pyrene; DL-PCBs; dioxin-like PCBs; NDL-PCBs; non-dioxin-like PCBs; HepG2; human hepatocellular carcinoma cell line; ANF; α-Naphthoflavone; Est; 17β-estradiol; NAC; N-A

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

NF-κB increased expression of 17β-hydroxysteroid dehydrogenase 4 promotes HepG2 proliferation via inactivating estradiol

Keywords: NF-κB; HSD17B4; HepG2; E2; HCC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Prolyl isomerase Pin1 regulates cadmium-induced autophagy via ubiquitin-mediated post-translational stabilization of phospho-Ser GSK3αβ in human hepatocellular carcinoma cells

Keywords: Cadmium (PubChem CID: 10986); SB216763 (PubChem CID:176158); Juglone (PubChem CID:3806); MG132 (PubChem CID:462283); Cycloheximide (PubChem CID:6197)Pin1; Autophagy; Cadmium; HepG2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis and in vitro antitumor activity of novel N-substituted-4-phenyl/benzylphthalazin-1-ones

Keywords: Phthalazin-1-one; Antitumor activity; HepG2; Apoptosis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The influence of ATM, ATR, DNA-PK inhibitors on the cytotoxic and genotoxic effects of dibenzo[def,p]chrysene on human hepatocellular cancer cell line HepG2

Keywords: Dibenzo[def,p]chrysene; PIKK inhibitors; DNA damage signaling; HepG2;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Keywords: ACFs; aberrant crypt foci; AO/EB; acridine orange/ethidium bromide; CPCSEA; Committee for the Purpose of Control and Supervision of Experiments on Animals; CMC; carboxymethylcellulose; DMEM; Dulbecco's minimum essential media; DMSO; dimethyl sulfoxide;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells

Keywords: AML; acute myeloid leukemia; BSA; bovine serum albumin; DCFH-DA; 2′,7′-dichlorofluorescensin diacetate; DCM; dilated cardiomyopathy; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; FZD; furazolidone; HepG2; hepatoblastoma cell line; IGF-1; insulin-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Gingerols and shogaols: Important nutraceutical principles from ginger

Keywords: BSA; bovine serum albumin; COX; cyclooxygenase; GN; gingerol; HepG2; human hepatoma G2; iNOS; inducible NO synthase; LPS; lipopolysaccharide; MBC; minimum bactericidal concentration; MIC; minimal inhibitory concentration; NF-κB; nuclear factor-kappa B; N

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells

Keywords: Curcumin; Cancer; HepG2; Apoptosis; Cell cycle; DNA damage

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells

Keywords: Lipoapoptosis; SHIP2; Palmitate; ROS; Akt; FOXO-1; Liver; HepG2; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

SH2 domain-containing inositol 5-phosphatase (SHIP2) inhibition ameliorates high glucose-induced de-novo lipogenesis and VLDL production through regulating AMPK/mTOR/SREBP1 pathway and ROS production in HepG2 cells

Keywords: AMPK; AMP-activated protein kinase; ACC; Acyl COA Carboxylase; BSA; Bovine Serum Albumin; DHE; Dihydroethidium; DPI; Diphenylene iodonium; ERK; Extracellular signal-regulated kinase; FAS; Fatty Acid Synthase; FBS; Fetal bovine serum; FOXO1; Forkhead box p

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Litchi chinensis: medicinal uses, phytochemistry, and pharmacology

Keywords: Aq; aqueous; A549; human lung cancer; ABTS; 2,2′-Azinobis(3-ethylbenzothiazoline-6-sulfonate); ADP; adenosine diphosphate; AGS; human gastric epithelial; ADPRTL1; ADP-ribosyltransferase (NAD+poly (ADP-ribose) polymerase)-like 1); ADAM9; metalloproteinas

دانلود رایگان متن کامل مقاله ISI 106 صفحه سال انتشار : 2015 سفارش ترجمه

A natural phenylpropionate derivative from Mirabilis himalaica inhibits cell proliferation and induces apoptosis in HepG2 cells

Keywords: Mirabilis himalaica; Cell proliferation; Cell cycle; Apoptosis; HepG2;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Chemotypes sensitivity and predictivity of in vivo outcomes for cytotoxic assays in THLE and HepG2 cell lines

Keywords: Chemotype sensitivity; Cytotoxicity assay; THLE; HepG2; ATP depletion assay; Exploratory Toxicology Studies; c Log P; TPSA

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Proposing a Caco-2/HepG2 cell model for in vitro iron absorption studies

Keywords: Caco-2; HepG2; Hepcidin; Coculture; Intestinal; Cell model;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Biotransformation of 20(R)-panaxadiol by the fungus Rhizopus chinensis

Keywords: Ginseng; Panax ginseng; Araliaceae; Rhizopus chinensis; 20(R)-Panaxadiol; Biotransformation; HepG2; NF-κB;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of the effects of ellagic acid (EA) on 7,12-dimethylbenz(α) anthracene (DMBA) induced micronuclei in mammalian cells in vitro and in vivo

Keywords: Ellagic acid; Micronucleus assay; DMBA; HepG2; Bone marrow;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه