دانلود مقالات ISI درباره Hif-1 + ترجمه فارسی

Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth

Keywords: EGLN; Egl-9 homologue; HIF-1; hypoxia-inducible factor-1; HNSCC; head and neck squamous cell carcinoma; PHD; prolyl hydroxylation domain protein; pVHL; von Hippel-Lindau protein; TMA; tissue microarray; RT-PCR; real-time PCR; Colon carcinoma; HIF-1α; Hyp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Constitutive HIF-1 activity in malignant melanoma

Keywords: Hypoxia; HIF-1; Melanoma; ROS; MAGE

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Hypoxia-Inducible Factor Signaling Provides Protection in Clostridium difficile-Induced Intestinal Injury

Keywords: Vascular Endothelial Growth Factor; Tumor Necrosis Factor; ITF/TFF3; Nitric Oxide Synthase; CDAD; C difficile-associated disease; DMOG; dimethyloxaloylglycine; HIF-1; hypoxia-inducible factor-1; HIF-1α(Ep−/−); targeted epithelial HIF-1α−/− knock

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

STAT1 represses hypoxia-inducible factor-1-mediated transcription

Keywords: Interferon-gamma; Hypoxia; STAT1; HIF-1; CXCR4; Transcriptional regulation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of cancer cell metabolism by hypoxia-inducible factor 1

Keywords: BNIP3; Glucose transporter; Glycolysis; HIF-1; Lactate dehydrogenase; MCT4; Mitochondrial autophagy; NHE1; Oxygen; PDK1; Warburg effect

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Usefulness of HIF-1 Imaging for Determining Optimal Timing of Combining Bevacizumab and Radiotherapy

Keywords: Antiangiogenesis; radiation; hypoxia imaging; hypoxia-inducible factor-1; HIF-1; bevacizumab;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Reduced Morg1 expression in ischemic human brain

Keywords: Morg1; Brain; Ischemia; HIF-1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Placental Stress and Pre-eclampsia: A Revised View

Keywords: Pre-eclampsia; Oxidative stress; Hypoxia; Systemic inflammatory response; sFlt-1; Endoglin; HIF-1; NF-kappaB;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors

Keywords: Nitric oxide; PHD activity; PHD2; HIF-1; pVHL; Feedback loop

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Transcriptional activation of hypoxia-inducible factor-1α by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

Keywords: HIF-1; hypoxia-inducible factor-1; ODD; oxygen-dependent degradation; FIH-1; factor inhibiting HIF-1; HDAC; histone deacetylase; HRE; hypoxia-response element; C-TAD; C-terminal activating domain; ID; inhibitory domain; TSA; trichostatin A; pVHL; von Hipp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Role of the intracellular localization of HIF-prolyl hydroxylases

Keywords: Hypoxia; Prolyl hydroxylase; HIF-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Transport of hypoxia-inducible factor HIF-1α into the nucleus involves importins 4 and 7

Keywords: HIF-1; Hypoxia; Nuclear import; Importin 4; Importin 7

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Thérapies antiangiogéniques et radiothérapie : du concept à l’essai clinique

Keywords: Angiogenèse; Radiothérapie; FGF-2; VEGF; Intégrines; Hypoxie; HIF-1; Cellules souches; Essai cliniqueAngiogenesis; Radiotherapy; FGF-2; VEGF; Integrins; Hypoxia; HIF-1; Stem cells; Clinical trial

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

The function of VEGF-A in lens development: Formation of the hyaloid capillary network and protection against transient nuclear cataracts

Keywords: tunica vasculosa lentis; anterior pupillary membrane; hyaloid vascular system; lens growth; VEGF-A; HIF-1; vascular regression; nuclear cataract

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies

Keywords: Angiogenesis; VEGF; Hypoxia; HIF-1; Bevacizumab; Cancer therapeutics; Topotecan; mTOR inhibitors

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Hypoxia and HIF-1α expression in the epiphyseal cartilage following ischemic injury to the immature femoral head

Keywords: Ischemic osteonecrosis; Avascular necrosis; Hypoxia inducible factor; HIF-1; Epiphyseal cartilage; Femoral head; Legg-Calve-Perthes disease;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

p300 expression is induced by oxygen deficiency and protects neuron cells from damage

Keywords: HIF-1; hypoxia-inducible factor 1; BCIP; 5-bromo-4-chloro-3-indoly-phosphate; NBT; nitroblue tetrazolium chloride; BSA; bovine serum albumin; DMSO; dimethyl sulfoxide; MTT; 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; NGF; nerve growth

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Cobalt induces oxidative stress in isolated liver mitochondria responsible for permeability transition and intrinsic apoptosis in hepatocyte primary cultures

Keywords: AdNT; adenine nucleotide translocase; AIF; apoptosis inducing factor; APF; 2-[6-(4′-amino)phenoxy-3H-xanthen-3-on-9-yl]benzoic acid; BHT; butylhydroxytoluene; BKA; bongkrekic acid; DMF; dimethyl formamide; CsA; cyclosporin A; cyt c; cytochrome c; DTE; d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Hypoxia and the metabolic phenotype of prostate cancer cells

Keywords: ALDO; aldolase; CS; citrate synthase; COX; cytochrome c oxidase; DCA; dichloroacetate; G3PDH; glyceraldehyde-3-phosphate dehydrogenase; G6PDH; glucose-6-phosphate dehydrogenase; HK; hexokinase; HIF; hypoxia-inducible factor; LDH; lactate dehydrogenase; NR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

HIF-1α induces MXI1 by alternate promoter usage in human neuroblastoma cells

Keywords: MXI1; Hypoxia; HIF-1; Hypoxia responsive elements (HRE); Neuroblastoma; MYCN

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib

Keywords: Doxorubicin; Sunitinib; Anti-angiogenesis; P-glycoprotein; Drug transport; Hypoxia; High-dose; Glycolysis; ATP levels; Energy metabolism; Kinases; Tumor stroma; Hedgehog; HIF-1; STAT3; Quantitative resistance assays

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Neural phosphoproteomics of a chronic hypoxia model-Lymnaea stagnalis

Keywords: proteomics; phosphorylation; hypoxia tolerance; Pro-Q Diamond; electrophysiology; behavior; Akt; protein kinase B; AP; action potential; APD50; action potential duration measured as the time from the overshoot to 50% repolarization to resting potential; C

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Hypoxia regulates inflammatory gene expression in endothelial cells

Keywords: Endothelial cell; Inflammatory genes; Leukocyte adhesion; Hypoxia; NF-kB; HIF-1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Cellular and molecular pathways linking inflammation and cancer

Keywords: COX-2; cycloxygenase-2; TGFβ; transforming growth factor-β; HIF-1; hypoxia inducible factor 1; STAT-3; signal transducers and activator of transcription-3; TAMs; tumour-associated macrophages; TNFalpha; tumour necrosis factor alpha; TEMs; Tie2-expressin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors

Keywords: VHL; TGFBI; KLF10; TGF-β; ECM; HIF-1; VHL targets; Clear cell carcinoma; BIGH3; Keratoepithelin; Oncogenic survival

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Preferential expression of the novel alternative isoform I.3 of hypoxia-inducible factor 1α in activated human T lymphocytes

Keywords: T cells; TCR; PBMC; HIF-1; Hypoxia-inducible factor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes

Keywords: Adipocyte; Adipokine; Adipose tissue; HIF-1; Gene expression; Hypoxia; Metallothionein; Obesity; Oxygen tension; PCR arrays;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Hypoxia upregulates the histone demethylase JMJD1A via HIF-1

Keywords: Histone demethylase; Hypoxia; Jumonji domain containing 1A; JMJD1A; JHDM2A; HIF-1; Promoter

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells

Keywords: Hypoxia; HIF-1; Sphingosine-1-phosphate; Sphingosine kinase-1; Endothelial cells; Migration

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Diameter of tumor blood vessels is a good parameter to estimate HIF-1-active regions in solid tumors

Keywords: HIF-1; hypoxia-inducible factor-1; HRE; hypoxia-response element; ODD; oxygen-dependent degradation; luc; luciferase; 5HREp; 5 copies of HRE promoter; GFP; green fluorescent protein; Hypoxia; Angiogenesis; Hypoxia-inducible factor-1 (HIF-1); Vascular endo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Hypoxia induces a novel signature of chromatin modifications and global repression of transcription

Keywords: Hypoxic stress; Chromatin; HIF-1; Transcription; Repression;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Expression of hypoxia inducible factor-1α in tumors of patients with glioblastoma multiforme and transitional meningioma

Keywords: Brain tumors; Glioblastoma multiforme; HIF-1; Hypoxia; Meningioma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Cortical spreading depression induces the expression of iNOS, HIF-1α, and LDH-A

Keywords: CSD; iNOS; HIF-1; LDH-A; mRNA; neuroprotectionCSD, cortical spreading depression; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HIF-1, hypoxia inducible factor-1; iNOS, inducible nitric oxide synthase; LDH-A, lactate dehydrogenase-A; l-NAME, Nω-nitro-l

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Concomitant inhibition of prolyl hydroxylases and ROCK initiates differentiation of mesenchymal stem cells and PC12 towards the neuronal lineage

Keywords: Mesenchymal stem cell; Prolyl hydroxylase; Neural differentiation; PC12; HIF-1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Targeting tumour hypoxia in breast cancer

Keywords: Hypoxia; Breast cancer; HIF-1; Prognostic factor; Radioresistance; Chemoresistance; Gene profile

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

iNOS as a therapeutic target for treatment of human tumors

Keywords: Nitric oxide synthase; Nitric oxide; Hypoxia; Cancer; Radiation; Bioreductive drugs; HIF-1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

2-Oxoglutarate-dependent oxygenases control hepcidin gene expression

Keywords: Hepcidin; 2-Oxoglutarate-dependent oxygenases; Protein hydroxylation; Hypoxia; HIF-1; DFO; Cobalt; DMOG; IL-6;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

HIF-1α controls keratinocyte proliferation by up-regulating p21(WAF1/Cip1)

Keywords: HIF-1; hypoxia-inducible factor 1; ARNT; aryl hydrocarbon nuclear receptor translocator; HBS; HIF-1 binding site; ROS; reactive oxygen species; EPO; erythropoietin; DFO; desferrioxamine; CHX; cycloheximide; NAC; N-acetyl cysteine; DTT; dithiothreitol, ROT

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer

Keywords: DCIS; ductal carcinoma in situ; IDC; invasive ductal carcinoma; FACS; fluorescence activated cell sorting; ASK1; apoptosis signal regulating kinase 1; HIF-1; hypoxia inducible factor 1; MKK4; Map-kinase kinase-4; DNA-PKcs; DNA-dependent ser/thr protein ki

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular aspects of tumour hypoxia

Keywords: Tumour hypoxia; HIF-1; Hypoxic markers; Molecular response; Unfolded protein response, UPR

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Metallothionein rescues hypoxia-inducible factor-1 transcriptional activity in cardiomyocytes under diabetic conditions

Keywords: Diabetes; Metallothionein; HIF-1; VEGF; Cardiomyocytes

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma

Keywords: N-myc downstream-regulated gene 1; Hypoxia; HIF-1; Carcinoma, hepatocellularNDRG1, N-myc downstream regulated gene-1; HIF-1, hypoxia-inducible factor-1; HCC, hepatocellular carcinoma; O2, oxygen; siRNA, short-interfering RNA; DMOG, dimethyloxallyl glycine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPα and STAT-3

Keywords: Hepcidin; Reactive oxygen species; C/EBPα; STAT-3; HIF-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor α/retinoid X receptor

Keywords: Hypoxia; HIF-1; PPARα; M-CPT I; Neural lipid accumulation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1α inhibitors

Keywords: Hypoxia; Hypoxia-inducible factor; HIF-inhibitor; HIF-1; Isonicotinic/nicotinic acid analogues

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Exploring the role of HIF-1 in early angiogenesis and response to radiotherapy

Keywords: Hypoxia; HIF-1; Angiogenesis; Radiotherapy response

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Mechanism of vascular endothelial growth factor expression mediated by cisplatin in human ovarian cancer cells

Keywords: CDDP, cisplatin; VEGF, vascular endothelial growth factor; HIF-1, hypoxia-inducible factor 1; KDR, VEGF receptor 2Cisplatin; Ovarian cancer; HIF-1; VEGF; Angiogenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Bucillamine mechanism inhibiting IL-1β-induced VEGF production from fibroblast-like synoviocytes

Keywords: Bucillamine; VEGF; Sinoviocyte; IL-1; HIF-1; Sp1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Hypoxia Modulates HLA-G Gene Expression in Tumor Cells

Keywords: HLA-G; cancer cells; hypoxia; HIF-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The yeast genome may harbor hypoxia response elements (HRE)

Keywords: ARNT, aryl-hydrocarbon receptor nuclear translocator; HBS, HIF-1 binding site; HIF-1, hypoxia-inducible factor-1; HRE, hypoxia response element; LORE, low oxygen responsive element.Anaerobic genes; Gene annotation; HIF-1; HRE; Hypoxia; LORE; Regulatory se

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه