دانلود مقالات ISI درباره Hif-1 + ترجمه فارسی

Inhibiting the phosphatidylinositide 3-kinase pathway blocks radiation-induced metastasis associated with Rho-GTPase and Hypoxia-inducible factor-1 activity

Keywords: Radiotherapy; Metastasis; PI3K; HIF-1; Rho-GTPases; GDC-0941;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

p53 activation by Ni(II) is a HIF-1α independent response causing caspases 9/3-mediated apoptosis in human lung cells

Keywords: Nickel; p53; Apoptosis; HIF-1; Hypoxia; Cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleKEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants

Keywords: ARE; anti-oxidant response element; HIF-1; hypoxia inducible factor-1; HKO; hepatocyte knockout; HO-1; heme-oxygenase-1; HRE; hypoxia response element; H2O2; hydrogen peroxide; IRI; ischemia/reperfusion injury; Keap1; Kelch-like ECH-associated protein 1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The alteration of hypoxia inducible factor-1 (HIF-1) and its target genes in mood disorder patients

Keywords: HIF-1; Hypoxia inducible factor-1; VEGF; vascular endothelial growth factor; MDD; major depressive disorder; BPD; bipolar disorder; BDNF; brain-derived neurotrophic factor; GDNF; glial cell line-derived neurotrophic factor; EPO; erythropoietin; GLUT1,3; g

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization

Keywords: HIF-1; hypoxia inducible factor 1; ARNT; aryl hydrocarbon receptor nuclear translocator; MgcRacGAP; male germ cell Rac GTPase activating protein; bHLH; basic helix-loop-helix; PAS; Per-ARNT-Sim; ODD; oxygen dependent degradation; pVHL; von Hippel-Li

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer

Keywords: Hippo pathway; Bone metastasis; HIF-1; Microenvironment; Hypoxia;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway

Keywords: ALT; alanine aminotransferase; AST; aminotransferase; BUN; blood urea nitrogen; CRE; creatinine; Ctsd; cathepsin D; FACS; flow cytometry analysis; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HCC; hepatocellular carcinoma; Hb; hemoglobins; HIF-1; hypo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors

Keywords: Bone metastasis; E-cadherin; Hippo pathway; HIF-1; PPARγ;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

A1 and A3 adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes

Keywords: ActD; actinomycin D; Ado; adenosine; ADA; adenosine deaminase; BAY 60-6583; 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; CHA; N(6)-cyclohexyladenosine; CGS 21680; 2-p-(2-carboxyethyl)phenethylamino-5′-N-ethylcarb

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Echinomycin in the prevention of heterotopic ossification – An experimental antibiotic agent shows promising results in a murine model

Keywords: Echinomycin; Heterotopic; Ossification; Murine; VEGF; HIF-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Exposure to hypoxia following irradiation increases radioresistance in prostate cancer cells

Keywords: Radiation; Hypoxia; Prostate cancer; HIF-1; Resistance

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors

Keywords: SENP1; Non-peptidic inhibitors; HIF-1; deSUMOylation; Selective inhibition

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular basis of polycythemic disorders due to aberrant hypoxia sensing and its relevance to acute leukemia

Keywords: acute leukemia forum; Beutler; cancer cell metabolism; glycolysis; hypoxia-inducible factor; HIF; HIF-1; HIF-2; HIF-3; IDH1; IDH2; isocitrate dehydrogenase; leukemia; polycythemia; tumorigenesis; von Hippel-Lindau; Warburg

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress

Keywords: CoCl2; cobalt chloride; DIC; differential interference contrast; DiI; 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; GSK-3; glycogen synthase kinase 3; HIF-1; hypoxia-inducible factor-1; LPS; lipopolysaccharide; Mal; MyD88 adapt

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma

Keywords: Head and neck squamous cell carcinoma; STAT3; HIF-1; Stattic; Radiation therapy; Radiosensitization

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research reportRepeated mild hypoxic exposures decrease anxiety-like behavior in the adult mouse together with an increased brain adrenomedullin gene expression

Keywords: AM; adrenomedullin; BDNF; brain derived neurotrophic factor; EPO; erythropoietin; HIF-1; hypoxia inducible factor 1; VEGF; vascular endothelial growth factor; Hypoxia; Anxiolytic; Adrenomedullin; VEGF; Hypoxia inducible factors; Memory;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

p53 Inhibits Vascular Endothelial Growth Factor Expression in Solid Tumor

Keywords: p53; VEGF; HIF-1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue

Keywords: Head and neck cancer; Tongue; CXCR4; SDF-1; CXCL12; CA9; HIF-1; Vimentin; E-cadherin; Oral cancer; Squamous cell carcinoma

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation of S100A4 expression via the JAK2-STAT3 pathway in rhomboid-phenotype pulmonary arterial smooth muscle cells exposure to hypoxia

Keywords: JAKs; Janus kinases; STATs; signal transducers and activators of transcription; HIF-1; hypoxia induced factor 1; PASMCs; pulmonary arterial smooth muscle cells; VSMCs; vascular smooth muscle cells; R-SMCs; rhomboid VSMCs; S-SMCs; spindle-shaped SMCs; PAH;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering

Keywords: Tissue engineering; Cartilage repair; Hypoxia; Mesenchymal stem cells; Chondrocytes; HIF-1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1α targeted gene expression

Keywords: TPZ; Tirapazamine; HIF-1; hypoxia inducible factor-1; VEGF; vascular endothelial growth factor; GLUT1; glucose transporter 1; ELISA; enzyme-linked immunosorbent; EPO; erythropoietin; GPI; glucose phosphate isomerase; GDEPT; gene-directed enzyme prodrug th

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Time-dependent changes in protein expression in rainbow trout muscle following hypoxia

Keywords: HIF-1; hypoxia inducible factor 1; Aquaculture; Hypoxia; Oxidative stress; Proteomics; Rainbow trout;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

Keywords: acriflavine; angiopoietin-like 4; collagen crosslinking; digoxin; extravasation; HIF-1; lysyl oxidase; metastatic niche formation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Down-regulation of MutS homolog 3 by hypoxia in human colorectal cancer

Keywords: hMSH3; Down-regulation; Hypoxia; HIF-1; p53; Colorectal cancer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Oxidative stress and metal carcinogenesis

Keywords: AP-1; activator protein-1; ARE; antioxidant response element; CAT; catalase; CBD; chronic beryllium disease; DFX; desferoxamine; EGF; epidermal growth factor; ERK; extracellular signal-regulated kinase; ESR; electron spin resonance; GF; growth factor; GPx

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors

Keywords: HIF-1; Angiogenesis; Anticancer drug; Small molecule inhibitors

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Impaired expression of hypoxia-inducible factor-1α in cystic fibrosis airway epithelial cells – A role for HIF-1 in the pathophysiology of CF?

Keywords: HIF-1; Cystic fibrosis; Hypoxia; Pseudomonas aeruginosa

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion

Keywords: MT1-MMP; Membrane-type-1 matrix metalloproteinase; APBA3; amyloid beta (A4) precursor protein-binding, family A, member 3; HIF-1; Hypoxia Inducible Factor-1; FIH-1; Factor of Inhibiting HIF-1; ECM; extracellular matrix; ATP; adenosine triphosphate; MEF; m

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Sensory plasticity of the carotid body: Role of reactive oxygen species and physiological significance

Keywords: Sensory plasticity; Recurrent apneas; Neurotransmitters; H2O2; Superoxide anion; HIF-1; HIF-2; Pet-1 transcription factor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway

Keywords: Acacetin; VEGF; Angiogenesis; HIF-1; AKT;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Research ReportSpatial-temporal expression of NDRG2 in rat brain after focal cerebral ischemia and reperfusion

Keywords: DAPI; diamidino-phenyl-indole; GFAP; glial fibrillary acidic protein; HIF-1; hypoxia-inducible factor-1; MCAO; middle cerebral artery occlusion; NDRG2; N-myc downstream regulated gene 2; TUNEL; terminal deoxynucleotidyl transferase nick-end labeling; NDRG

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Antidepressant hyperforin up-regulates VEGF in CNS tumour cells

Keywords: bp; base pairs; BrdU; 5-bromo-2-deoxyuridine; BSA; bovine serum albumin; CMV; cytomegalovirus; CNS; central nervous system; DMSO; dimethyl sulphoxide; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescence-activated cell sorting; FBS; foetal bovine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Cdk5 interacts with Hif-1α in neurons: A new hypoxic signalling mechanism?

Keywords: Cdk5/p35; Oxygen deprivation; Hif-1; Cell death;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Copper and homocysteine in cardiovascular diseases

Keywords: Copper; Homocysteine; Ceruloplasmin; Endothelium; Heart; Blood vessel; ADMA; Asymmetric dimethyl-arginine; BHMT; Betaine:homocysteine methyltransferase; CBS; Cystathionine β-synthase; CCO; Cytochrome c oxidase; CGL; Cystathionine γ-lyase; Cu; Copper; DR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Hypoxia-induced angiogenesis is delayed in aging mouse brain

Keywords: HIF-1; VEGF; Ang-2; COX-2; Brain capillary density

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Uncovering the role of hypoxia inducible factor-1α in skin carcinogenesis

Keywords: Bax; Bcl-2-associated X protein; BCC; Basal cell carcinoma; Bcl-2; B cell lymphoma; Bcl-xL; B-cell lymphoma-extra large; BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; CMM; Cutaneous malignant melanoma; CBP; cyclic-AMP response element

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Interactive effects of cadmium and hypoxia on metabolic responses and bacterial loads of eastern oysters Crassostrea virginica Gmelin

Keywords: AEC; adenylate energy charge; ADP; adenosine-5′-diphosphate; AMP; adenosine-5′-monophosphate; ATP; adenosine-5′-triphosphate; ASW; artificial seawater; Cd; cadmium; cDNA; complementary DNA; COX; complex IV (cytochrome c oxidase); CS; citrate synthas

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Nitric oxide: A short lived molecule stays alive

Keywords: Superoxide; Guanylyl cyclase; Mitochondria; HIF-1; Tumor; Nitrosation; Nitration; Lipid nitration;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

P70S6K 1 regulation of angiogenesis through VEGF and HIF-1α expression

Keywords: p70S6K1; VEGF; HIF-1; Tumor angiogenesis; siRNA

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Hypoxia and mitochondrial oxidative metabolism

Keywords: HIF-1; hypoxia-inducible factor 1; HIF; hypoxia-inducible factor; IF1; ATP synthase natural inhibitor protein; F1F0 ATPase; ATP synthase; COX; cytochrome c oxidase; ΔΨm; electrical membrane potential of mitochondria; mtDNA; mitochondrial DNA; AMPK; AMP-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: Roles in skeletal muscle growth and differentiation

Keywords: IGF; IGFBP; Myoblast; Proliferation; Hypoxia; HIF-1; MAPK; Akt; mTOR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Experimental Evaluation of Inhibitory Effect of 10-Hydroxycamptothecin on Hypoxia-inducible Factor-1α Expression and Angiogenesis in Liver Tumors after Transcatheter Arterial Embolization

Keywords: HCPT; 10-hydroxycamptothecin; HIF-1; hypoxia-inducible factor-1; VEGF; vascular endothelial growth factor;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Relationship among circulating hemoglobin, nitric oxide synthase activities and angiogenic poise in red- and white-blooded Antarctic notothenioid fishes

Keywords: Hb; hemoglobin; Hct; hematocrit; NO; nitric oxide; NOS; nitric oxide synthase; eNOS; endothelial nitric oxide synthase; iNOS; inducible nitric oxide synthase; nNOS; neuronal nitric oxide synthase; NOx; nitrite plus nitrate; VEGF; vascular endothelial grow

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Hypoxia-inducible factor-1 (HIF-1)-independent microvascular angiogenesis in the aged rat brain

Keywords: Aging; Angiogenesis; Brain; Hypoxia; HIF-1; Microvessel; PGC-1α; VEGF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Hypoxic preconditioning provides neuroprotection and increases vascular endothelial growth factor A, preserves the phosphorylation of Akt-Ser-473 and diminishes the increase in caspase-3 activity in neonatal rat hypoxic-ischemic model

Keywords: Akt; protein kinase B; HI; hypoxia-ischemia or hypoxic-ischemic; HIF-1; Hypoxia-inducible factor 1; LH; left hemisphere; PC; hypoxic preconditioning; RH; right hemisphere; VEGF; Vascular endothelial growth factor A; Neurotrophin; Neuroprotection; Apop

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Transcriptional regulation and functional implication of the grass carp CITED1 (gcCITED1) in the negative regulation of HIF-1

Keywords: Hypoxia; CITED; HIF-1; CBP/p300; Fish

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The effects of hypoxia on hemocyanin regulation in Cancer magister: Possible role of Hypoxia-Inducible Factor-1

Keywords: Cancer magister; Hemocyanin; HIF-1; Hypoxia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Gene Expression Profiles of Epidermal Growth Factor Receptor, Vascular Endothelial Growth Factor and Hypoxia-inducible Factor-1 with Special Reference to Local Responsiveness to Neoadjuvant Chemoradiotherapy and Disease Recurrence After Rectal Cancer Surg

Keywords: EGFR; HIF-1; preoperative chemoradiotherapy; rectal cancer; recurrence; tumour regression; VEGF;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

HIF-1α signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells

Keywords: HIF-1; Nrf2; Trx1; NOX1; Intermittent hypoxia; Reoxygenation; Free radicals

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells

Keywords: OXPHOS; oxidative phosphorylation; HIF-1; hypoxia-inducible factor-1; DNP; dinitrophenol; RH-123; Rhodamine-123; TMRM; tetramethylrhodamine methylester; MitoTracker Red; chloromethyl-X-rosamine (CMX-Ros); ΔΨm; mitochondrial electrical membrane potential

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه