دانلود مقالات ISI درباره HMG-CoA ردوکتاز + ترجمه فارسی

Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors

Keywords: HMG-CoA ردوکتاز; 3,3-Diphenylpentane; DPP skeleton; HMG-CoA reductase; Statin;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

IL-1 regulates the Cyp7a1 gene and serum total cholesterol level at steady state in mice

Keywords: HMG-CoA ردوکتاز; Constitutive expression; Cholesterol; Cyp7a1; HMG-CoA reductase; Inflammatory cytokine; Liver; IL-1; Mouse; Sex difference;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Mevalonate pathway modulation is associated with hepatitis C virus RNA presence in peripheral blood mononuclear cells

Keywords: HMG-CoA ردوکتاز; Cholesterol; Geranylgeranyl pyrophosphate; Hepatitis C virus; HMG-CoA reductase; LDL-C; Mevalonate pathway

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of dietary flaxseed oil on cholesterol metabolism of hamsters

Keywords: HMG-CoA ردوکتاز; Flaxseed oil; Serum lipids; Hepatic cholesterol/triacylglycerol contents; Faecal cholesterol/triacylglycerol excretion; HMG-CoA reductase; CYP7A1; LDL receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Cholesterol synthesis in the lactating cow: Induced expression of candidate genes

Keywords: HMG-CoA ردوکتاز; Cholesterol; HMG-CoA reductase; HMG-CoA synthase; SREBP; Scap;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients

Keywords: HMG-CoA ردوکتاز; Alzheimer disease; HMG-CoA reductase; Isoprenoids; Farnesylpyrophosphate; Geranylgeranylpyrophosphate; Prenylation; GTPases; Cholesterol; Statins;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Green and black tea extracts inhibit HMG-CoA reductase and activate AMP kinase to decrease cholesterol synthesis in hepatoma cells

Keywords: HMG-CoA ردوکتاز; Cholesterol; AMP kinase; HMG-CoA reductase; Hepatoma cells; Tea

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH

Keywords: HMG-CoA ردوکتاز; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; FFA; free fatty acids; TG; triglycerides; SREBP-2; sterol regulatory element-binding protein-2; SREBP-1c; sterol regulatory element-binding protein-1c; HMG-CoA reductase; hydro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones

Keywords: HMG-CoA ردوکتاز; HMG-CoA reductase; Quinoline; Mevalonolactone; Synthesis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target

Keywords: HMG-CoA ردوکتاز; Diallyldisulfide; HMG-CoA reductase; SREBP-2; CREB; NF-Y; NF-κB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Structure and synthesis of polyisoprenoids used in N-glycosylation across the three domains of life

Keywords: HMG-CoA ردوکتاز; LLO; lipid-linked oligosaccharide; OST; oligosaccharide transferase; IPP; isopentenyl pyrophosphate; DMAPP; dimethylallyl pyrophosphate; MVA; mevalonate; DOXP; 1-deoxy-D-xylulose-5-phosphate; HMG-CoA; 3-hydroxy-3methylglutaryl-CoA; HMGS; HMG-CoA synthase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Special relationship between sterols and oxygen: Were sterols an adaptation to aerobic life?

Keywords: HMG-CoA ردوکتاز; CHO; Chinese hamster ovary; DHCR24; 3β-hydroxysterol-Δ24-reductase; EPR; electron paramagnetic resonance; ESR; electron spin resonance; H2O2; hydrogen peroxide; HIF-1α; hypoxia-inducible factor 1α; HMG-CoA reductase; 3-hydroxy-3-methyl-glutaryl-coenzy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Quantification of statin effects on hepatic cholesterol synthesis by transient 13C-flux analysis

Keywords: HMG-CoA ردوکتاز; Metabolic flux analysis; Non-stationary 13C-labeling; Mammalian cells; Hepatic metabolism; HMG-CoA reductase; Atorvastatin; Intracellular metabolite concentrations; Metabolic control analysis

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Long-term effects of resveratrol supplementation on suppression of atherogenic lesion formation and cholesterol synthesis in apo E-deficient mice

Keywords: HMG-CoA ردوکتاز; Resveratrol; Apo E-deficient mice; LDL-cholesterol; Paraoxonase; HMG-CoA reductase; Anti-atherogenic property; Aortic fatty streak;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway

Keywords: HMG-CoA ردوکتاز; Simvastatin; Bortezomib; Apoptosis resistance; Geranylgeranyl pyrophosphate; HMG-CoA reductase; Proteasome; RhoA; Mcl-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

Keywords: HMG-CoA ردوکتاز; LDL-C; HMG-CoA reductase; Atorvastatin; Rosuvastatin; Organic anion transporting polypeptides; Hydrophilicity; Lipophilicity; C log P; L6-myocytes; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: A randomized trial in healthy men

Keywords: HMG-CoA ردوکتاز; Ezetimibe; Simvastatin; LDL receptor; HMG-CoA reductase; Gene expression; PCSK9; NPC1L1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Antioxidative and hypocholesterolemic activities of water-soluble puerarin glycosides in HepG2 cells and in C57 BL/6J mice

Keywords: HMG-CoA ردوکتاز; Puerarin glycoside; Low-density lipoprotein receptor; HMG-CoA reductase; Antioxidant

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol

Keywords: HMG-CoA ردوکتاز; ER; endoplasmic reticulum; HDL; high-density lipoprotein; HMG-CoA reductase; hydroxy-3-methylglutaryl coenzyme A reductase; SR-BI; scavenger receptor class B type I;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Pyrazole inhibitors of HMG-CoA reductase: An attempt to dramatically reduce synthetic complexity through minimal analog re-design

Keywords: HMG-CoA ردوکتاز; HMG-CoA reductase; Cholesterol; Atherosclerosis; Statin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytes

Keywords: HMG-CoA ردوکتاز; Cholesterol and lipids metabolism; HMG-CoA reductase; Bile acid synthesis; Acetyl CoA carboxylase-1; Fatty acid synthase; SREBPs; Mitochondria; 5-Cholesten-3β; 25-Diol 3-sulfate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Increased gene expression of liver SREBP-2 in experimental chronic renal failure

Keywords: HMG-CoA ردوکتاز; Chronic renal failure; Sterol regulatory element-binding protein-2 (SREBP-2); HMG-CoA reductase; LDL-receptor; Hypercholesterolemia; Cholesterol synthesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of reduced levels of the LDL receptor of Ehrlich ascites tumor cells on cholesterol uptake and cell proliferation: A coculture study with baby hamster kidney cells

Keywords: HMG-CoA ردوکتاز; Coculture; HMG-CoA reductase; Cholesterol transfer; Antisense cDNA; Transfection; Anti-LDLr antibody; Tumor cell proliferation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Inability to fully suppress sterol synthesis rates with exogenous sterol in embryonic and extraembyronic fetal tissues

Keywords: HMG-CoA ردوکتاز; SLOS; Smith-Lemli-Opitz syndrome; DHCR7; 3β-hydroxysterol Δ7-reductase; HMGR; HMG-CoA reductase; SREBP; sterol regulatory element binding protein; SCAP; SREBP cleavage-activating protein; DPS; digitonin-precipitable sterols; Shh; Sonic hedgehog; Cho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

The liver plays a key role in whole body sterol accretion of the neonatal Golden Syrian hamster

Keywords: HMG-CoA ردوکتاز; SLOS, Smith–Lemli–Opitz syndrome; DPS, digitonin-precipitable sterols; HMGR, HMG CoA Reductase; SREBP, sterol regulatory element binding proteinDevelopment; Cholesterol; Smith–Lemli–Opitz; Cholestasis; HMG-CoA reductase; Neonate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Hepatic cytochrome P450 reductase-null mice reveal a second microsomal reductase for squalene monooxygenase

Keywords: HMG-CoA ردوکتاز; Cholesterol synthesis; Lanosterol; Supernatant protein factor; HMG-CoA reductase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Neurodegeneration in autoimmune demyelination: Recent mechanistic insights reveal novel therapeutic targets

Keywords: HMG-CoA ردوکتاز; MS; EAE; Neuronal damage; HMG-CoA reductase; EGCG; TRAIL

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Antioxidant and antiplatelet effects of rosuvastatin in a hamster model of prediabetes

Keywords: HMG-CoA ردوکتاز; AEC; aortic endothelial cells; DPI; diphenyleneiodonium chloride; FF; fructose-fed; HMG-CoA reductase; 3-hydroxy-3-methylglutaryl coenzyme A reductase; HRP; horseradish peroxidase; Mn(III)TMPyP; Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin pentachloride;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of hyperhomocysteinemia on cardiovascular risk factors and initiation of atherosclerosis in Wistar rats

Keywords: HMG-CoA ردوکتاز; Hyperhomocysteinemia; Atherosclerosis; HMG-CoA reductase; P2 receptors; Caveolin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Comparison of biochemical effects of statins and fish oil in brain: The battle of the titans

Keywords: HMG-CoA ردوکتاز; HMG-CoA reductase; Statin; Fish oil; Eicosapentaenoic acid; Docosahexaenoic acid; Eicosanoids; Docosanoids; Oxidative stress; Inflammation; Neurological disorder

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2007 سفارش ترجمه

DnaJA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway

Keywords: HMG-CoA ردوکتاز; Cholesterol synthesis; SREBP; HMG-CoA reductase; Chaperone; Heat shock

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Lovastatin-induced RhoA modulation and its effect on senescence in prostate cancer cells

Keywords: HMG-CoA ردوکتاز; Lovastatin; Senescence; RhoA; Prostate carcinoma; HMG-CoA reductase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation

Keywords: HMG-CoA ردوکتاز; Hypercholesterolemia; Selenium; Apolipoprotein B; HMG-CoA reductase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Cryptic promoter activity in the coding region of the HMG-CoA reductase gene in Fusarium graminearum

Keywords: HMG-CoA ردوکتاز; Gibberella zeae; HMG-CoA reductase; Cryptic promoter

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Sensing cell stress and transformation through Vγ9Vδ2 T cell-mediated recognition of the isoprenoid pathway metabolites

Keywords: HMG-CoA ردوکتاز; Immunology; T lymphocytes; Gamma/delta T cell receptor; Isoprenoid biosynthesis; ABP; aminobiphosphonate; Ag; antigen; ApoA1; apolipoprotein A1; AS; ATP synthase; DC; dendritic cell; DMAPP; dimethylallyl pyrophosphate; DOXP; 1-deoxy-d-xylulose-5-phosphate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Supernatant protein factor stimulates HMG-CoA reductase in cell culture and in vitro

Keywords: HMG-CoA ردوکتاز; Squalene monooxygenase; Hepatoma cells; Cholesterol synthesis; HMG-CoA reductase; Supernatant protein factor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

SC-435, an ileal apical sodium-codependent bile acid transporter inhibitor alters mRNA levels and enzyme activities of selected genes involved in hepatic cholesterol and lipoprotein metabolism in guinea pigs

Keywords: HMG-CoA ردوکتاز; ASBT inhibitor; CETP; Cholesterol 7 alpha hydroxylase; HMG-CoA reductase; Guinea pigs;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Lovastatin alters the isoprenoid biosynthetic pathway in acute myelogenous leukemia cells in vivo

Keywords: HMG-CoA ردوکتاز; Lovastatin; Mevalonate pathway; Ras; HMG-CoA reductase; Isoprenylation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors

Keywords: HMG-CoA ردوکتاز; CAT; chloramphenicol acetyltransferase; CI#1; cyclase inhibitor #1; DMSO; dimethyl sulfoxide; ED50; effective dose for 50% growth inhibition; HMG-CoA reductase; hydroxymethylglutaryl-coenzyme A reductase; SBI; sterol biosynthesis inhibitor; TLC; thin laye

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix

Keywords: HMG-CoA ردوکتاز; Statins; HMG-CoA reductase; Squamous cell; Therapeutics; Phase I;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Regulation of HMG-CoA reductase in MCF-7 cells by genistein, EPA, and DHA, alone and in combination with mevastatin

Keywords: HMG-CoA ردوکتاز; HMG-CoA reductase; Breast cancer; Genistein; Docosahexaenoic acid; Eicosapentaenoic acids; Mevastatin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of dietary ratios of fatty acids on cholesterol metabolism in rats and on low-density lipoprotein uptake in hepatocytes

Keywords: HMG-CoA ردوکتاز; Acyl CoA:cholesterol acyltransferase; Cholesterol 7α-hydroxylase; HMG-CoA reductase; (PUFA+MUFA)/SFA ratio; Rat; Hepatocyte;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

150 kDa glycoprotein isolated from Solanum nigrum Linne enhances activities of detoxicant enzymes and lowers plasmic cholesterol in mouse

Keywords: HMG-CoA ردوکتاز; Solanum nigrum Linne; Glycoprotein; Hypolipidemic activity; Detoxicant enzymes; HMG-CoA reductase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Growth hormone promotes glomerular lipid accumulation in bGH mice

Keywords: HMG-CoA ردوکتاز; glomerulosclerosis; cholesterol; triglycerides; HMG-CoA reductase; low-density lipoprotein receptor; scavenger receptor; real time RT-PCR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه