دانلود مقالات ISI درباره Hsp90 + ترجمه فارسی

Sarcoplasmic/endoplasmic reticulum Ca2 + ATPase C674 promotes ischemia- and hypoxia-induced angiogenesis via coordinated endothelial cell and macrophage function

Keywords: BMDM; bone marrow derived macrophage; EC; endothelial cell; ELISA; enzyme linked immunosorbent assay; ER; endoplasmic reticulum; ERO1; endoplasmic reticulum oxidoreductin-1; GSH; glutathione; HAECs; human aortic endothelial cells; HLI; hind limb ischemia;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

SNX-25a, a novel Hsp90 inhibitor, inhibited human cancer growth more potently than 17-AAG

Keywords: Hsp90; SNX-25a; 17-AAG; Apoptosis; Cell growth; Client proteins;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular docking study, synthesis and biological evaluation of Schiff bases as Hsp90 inhibitors

Keywords: Hsp90; Schiff bases; Docking; Malachite green; MTT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation

Keywords: SMYD2; Human carcinogenesis; HSP90; Non-histone protein methylation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors

Keywords: Hsp90; Anti-cancer; Chaperone; Novobiocin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Genome-wide identification and analysis of FK506-binding protein gene family in peach (Prunus persica)

Keywords: FKBPs; FK506-binding proteins; FKBd; FK506-binding domain; PPIase; peptidyl-prolylcis-trans isomerase; TPR; tetratricopeptide repeat; CaM-BDs; calmodulin-binding domains; SD; single-domain; MD; multidomain; HSP90; heat streak protein 90; CDS; coding seque

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Drugging the HDAC6–HSP90 interplay in malignant cells

Keywords: Acetylation; cancer; HDAC6; HDAC6 inhibitor; HSP90; leukemia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Hsp90 inhibitor 17-AAG sensitizes Bcl-2 inhibitor (-)-gossypol by suppressing ERK-mediated protective autophagy and Mcl-1 accumulation in hepatocellular carcinoma cells

Keywords: HCC, hepatocellular carcinoma; Hsp90, heat shock protein 90; Bcl-2, B-cell lymphoma-2; LC3, microtubule-associated protein 1 light chain 3; CQ, chloroquine; ERK, extracellular regulated kinase(-)-Gossypol; Bcl-2; Hsp90; Autophagy; ERK

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis of potential allosteric modulators of Hsp90 by chemical glycosylation of Eupomatenoid-6

Keywords: Eupomatenoid; Phenol glycosylation; Hsp90; O-Benzoxazolyl imidate (OBox); Glycodiversification; Phase Transfer Catalysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular cloning, characterization and expression analysis of three heat shock responsive genes from Haliotis diversicolor

Keywords: Haliotis diversicolor; HSF1; HSBP1; HSP90; Stress

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and antiproliferative activity of novobiocin analogues as potential hsp90 inhibitors

Keywords: Hsp90; 4TCNA; 6BrCaQ; Cytotoxicity; Apoptosis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Saikosaponin D acts against corticosterone-induced apoptosis via regulation of mitochondrial GR translocation and a GR-dependent pathway

Keywords: MD; major depression; HPA axis; hypothalamic-pituitary-adrenal axis; CNS; central nervous system; GC; glucocorticoid; GR; glucocorticoid receptors; mPTP; mitochondrial permeability transition pore; MMP; mitochondrial membrane potential; GILZ; glucocor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Genome-wide identification and analysis of FK506-binding protein family gene family in strawberry (Fragaria Ã— ananassa)

Keywords: FKBPs; FK506-binding proteins; FKBd; FK506-binding domain; PPIase; peptidyl-prolylcis-trans isomerase; TPR; tetratricopeptide repeat; CaM-BDs; calmodulin-binding domains; SD; single-domain; MD; multidomain; TOR; target of rapamycin; HSP90; heat streak pro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The intricate interplay between RNA viruses and NF-κB

Keywords: ss; single-stranded; ds; double-stranded; HTLV; human T cell leukemia virus; SARS; severe acute respiratory syndrome; IAVs; influenza A viruses; IFN; interferon; IRF3; interferon regulatory factor 3; NF-κB; nuclear factor κB; TLRs; toll-like receptors;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular cloning, characterization and expression analysis of HSP60, HSP70 and HSP90 in the golden apple snail, Pomacea canaliculata

Keywords: Pomacea canaliculata; Heat shock protein; HSP60; HSP70; HSP90

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy

Keywords: BRCA1; breast cancer susceptibility gene 1; BRCT; Brca1 C-terminal; CHIP; chaperone-associated ubiquitin ligase; CYLD; cylindromatosis; DAPK; death-associated protein kinase; DUB; deubiquitinating enzyme); EGF; epidermal growth factor; FADD; fas-associate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression

Keywords: AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; CYP; cytochrome P450; ER; estrogen receptor; GR; glucocorticoid receptor; Hsp90; heat shock protein 90; Sp1; specificity protein; TCDD; 2,3,7,8-tetrachlorodibenzo-p-diox

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Anti-citrullinated heat shock protein 90 antibodies identified in bronchoalveolar lavage fluid are a marker of lung-specific immune responses

Keywords: Rheumatoid arthritis; Interstitial lung disease; Bronchoalveolar lavage fluid; Autoantibodies; HSP90; Citrullination;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Protein arginine methyltransferase 6 enhances ligand-dependent and -independent activity of estrogen receptor α via distinct mechanisms

Keywords: Steroid hormone receptor; Hsp90; Chaperone binding; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis and biological evaluation of 17-arylmethylamine-17-demethoxygeldanamycin derivatives as potent Hsp90 inhibitors

Keywords: Geldanamycin; Hsp90; Antitumor activities; Hepatotoxicity; Molecular dynamicsLYXIGHSXNFCRKO-FXUFJLTMSA-N

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction

Keywords: EphB6; EphB4; Hsp90; Internalisation; Receptor tyrosine kinase; Downregulation;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of minimum carbohydrate moiety in N-glycosylation sites of brain endothelial cell glycoprotein 96 for interaction with Escherichia coli K1 outer membrane protein A

Keywords: Escherichia coli K1; Invasion; Brain endothelium; Hsp90; Glycoprotein; Meningitis

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Hypoxia-inducible factor 1 contributes to N-acetylcysteine's protection in stroke

Keywords: HIF-1; Hsp90; NAC; Neuroprotection; Stroke; Free radicals;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis

Keywords: Docosahexaenoic acid (DHA); Lipid raft; Hsp90; EGFR; Akt; Cholesterol

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy

Keywords: Andrographolide; Hsp90; Src; Bcr-Abl; ROS; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Development of radamide analogs as Grp94 inhibitors

Keywords: Hsp90; Grp94

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Characterization of the Grp94/OS-9 Chaperone–Lectin Complex

Keywords: ER, endoplasmic reticulum; ERAD, ER-associated degradation; TMP, terminally misfolded protein; MRH, mannose recognition homology; ITC, isothermal titration calorimetry; CTE, C-terminal extension; BME, β-mercaptoethanolchaperone; Hsp90; Grp94; ER-associate

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression

Keywords: Hsp90; SmyD; HDAC6; Pih1; Tah1; Immunophilin;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

The level of heat shock protein 90 in pig Longissimus dorsi muscle and its relationship with meat pH and quality

Keywords: pH; HSP90; Water holding capacity;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2014 سفارش ترجمه

Human cytochrome P450 epoxygenases: Variability in expression and role in inflammation-related disorders

Keywords: Inflammation; Cytochrome P450; Epoxygenase; Epoxyeicosatrienoic acids; Variability; AA; arachidonic acid; AhR; aryl hydrocarbon receptor; AP-1; activator protein-1; bZIP; basic leucine zipper; CAR; constitutive androstane receptor; CCRP; cytoplasmic CAR r

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2014 سفارش ترجمه

FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance

Keywords: 11β-HSD; 11β-hydroxysteroid dehydrogenase; BSA; Bovine serum albumin; CNR1; Cannabinoid receptor 1; FBS; Fetal bovine serum; FKBP5; FK506-binding protein 5; FKBP51; 51 kDa FK506-binding protein 5; GEO; Gene Expression Omnibus; GR; Glucocorticoid recept

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors

Keywords: HSP90; Fragment-based drug discovery; Crystallography; CDI; 1,1′-carbonyldiimidazole; DCM; dichloromethane; DHP; 3,4-dihydro-2H-pyran; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; LHMDS; lithium hexamethyldisilazide;

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of diamine-linked 17-aroylamido-17-demethoxygeldanamycins as potent Hsp90 inhibitors

Keywords: Geldanamycin; Synthesis; Hsp90; Antitumor activities; Hepatotoxicity; Molecular dynamics; IQFIFIMIRUVGSQ-FIVLHBINSA-N;

دانلود رایگان متن کامل مقاله ISI 109 صفحه سال انتشار : 2014 سفارش ترجمه

Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice

Keywords: HSP90; HSP70; Type 2 diabetes; Pharmacology;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Aldehyde dehydrogenase and HSP90 co-localize in human glioblastoma biopsy cells

Keywords: Aldehyde dehydrogenase; Disulfiram; Glioblastoma; HSP90; Ritonavir; Stem cell; Temozolomide;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Radicicol, a heat shock protein 90 inhibitor, inhibits differentiation and adipogenesis in 3T3-L1 preadipocytes

Keywords: 17-AAG; 17-allylamino-17-demethoxygeldanamycin; BCS; bovine calf serum; C/EBPα; CCAAT element binding protein α; FABP4; fatty acid-binding protein 4; FACS; fluorescence-activated cell sorting; FAS; fatty acid synthase; FBS; fetal bovine serum; Hsp90; he

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Mutant γPKC that causes spinocerebellar ataxia type 14 upregulates Hsp70, which protects cells from the mutant's cytotoxicity

Keywords: γPKC; protein kinase Cγ; SCA14; spinocerebellar ataxia type 14; Hsp70; heat-shock protein 70; Hsp40; heat-shock protein 40; Hsp90; heat-shock protein 90; GFP; green fluorescent protein; PCs; Purkinje cells; WT; wild-type; LDH; lactate dehydrogenase; CHI

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Heat shock transcription factor 1 attenuates TNFα-induced cardiomyocyte death through suppression of NFκB pathway

Keywords: HSF1; Heat shock transcription factor 1; NFκB; Nuclear factor-κB; TNFα; tumor necrosis factor alpha; HSP70; heat shock proteins 70; HSP90; heat shock proteins 90; RelA; v-rel reticuloendotheliosis viral oncogene homolog A; RHD; Rel Homology Domain; NLS

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting the hydrophobic region of Hsp90's ATP binding pocket with novel 1,3,5-triazines

Keywords: Hsp90; Structure-based design; Cancer; Molecular docking; Triazines;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Factor XII-independent activation of the bradykinin-forming cascade: Implications for the pathogenesis of hereditary angioedema types I and II

Keywords: Bradykinin; factor XII; prekallikrein; kininogen; C1 inhibitor; APMSF; (p-Amidinophenyl)methanesulfonyl fluoride; C1-INH; C1 inhibitor; CTI; Corn trypsin inhibitor; HAE; Hereditary angioedema; HK; High-molecular-weight kininogen; Hsp90; Heat shock protein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

In silico investigations on HSP90 and its inhibition for the therapeutic prevention of breast cancer

Keywords: HSP90; Homology modeling; Protein-protein docking; Protein-ligand docking; 17-DMAG;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Loss of survivin in neural precursor cells results in impaired long-term potentiation in the dentate gyrus and CA1-region

Keywords: ACSF; artificial cerebrospinal fluid; αCaMKII; α-calmodulin-dependent kinase II; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ANOVA; analysis of variance; CA1; Cornu Ammonis area 1; Cre; cAMP response element; DG; dentate gyrus;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

β-Catenin signaling induces CYP1A1 expression by disrupting adherens junctions in Caco-2 human colon carcinoma cells

Keywords: ARNT; Ah receptor nuclear translocator; bHLH; basic helix-loop-helix; CTF2; E-cadherin carboxy terminal fragment 2; CYP1A1; cytochrome P-450 1A1; DAPT; N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester; EMT; epithelial-mesenchymal tr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of RNA interference by Hsp90 is an evolutionarily conserved process

Keywords: RNAi; RNA interference; GFP; green fluorescent protein; TRBP2; Tar (HIV)-RNA binding protein 2; Hsp90; RNAi; Argonaute; Dicer; Yeast;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Distinct profiles of oxidative stress-related and matrix proteins in adult bone and soft tissue osteosarcoma and desmoid tumors: A proteomics study

Keywords: Adult osteosarcoma; Desmoid tumor; EMILIN-1; HSP90; Periostin; Proteomics;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Cytoplasmic ribosomal protein S3 (rpS3) plays a pivotal role in mitochondrial DNA damage surveillance

Keywords: HSP70; HSP90; Mitochondria; Ribosomal protein S3; ROS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Construction and characterization of a forward subtracted library of blue mussels Mytilus edulis for the identification of gene transcription signatures and biomarkers of styrene exposure

Keywords: EST; expressed sequence tag; GO; gene ontology; GST; glutathione-S-transferase; Hsp90; heat shock protein 90; NR1DEF; nuclear receptor family 1 subfamily D, E or F; REF; means reference sequence; SO; styrene-7,8-oxide; SSH; suppression subtractive hybridi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization

Keywords: HIF-1; hypoxia inducible factor 1; ARNT; aryl hydrocarbon receptor nuclear translocator; MgcRacGAP; male germ cell Rac GTPase activating protein; bHLH; basic helix-loop-helix; PAS; Per-ARNT-Sim; ODD; oxygen dependent degradation; pVHL; von Hippel-Li

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways

Keywords: Hsp90; heat shock protein 90; MDR; multidrug resistance; MTT; 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide; 17-AAG; 17-(allylamino)-17-demethoxygeldanmycin; DMSO; dimethylsulfoxide; CML; chronic myeloid leukemia; FBS; fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2

Keywords: Cisp; cisplatin; ΔΨm; mitochondrial transmembrane potential; Hsp90; heat shock protein 90; IM; inner membrane; IP3R; inositol 1,4,5-triphosphate receptor; MLP; melphalan; MMP; mitochondrial membrane permeabilization; OM; outer membrane; PI; propidium io

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه