دانلود مقالات ISI درباره Hsp90 + ترجمه فارسی

Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2

Keywords: Cisp; cisplatin; ΔΨm; mitochondrial transmembrane potential; Hsp90; heat shock protein 90; IM; inner membrane; IP3R; inositol 1,4,5-triphosphate receptor; MLP; melphalan; MMP; mitochondrial membrane permeabilization; OM; outer membrane; PI; propidium io

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Structural and functional studies of Leishmania braziliensis Hsp90

Keywords: AUC; analytical ultracentrifugation; CD; circular dichroism; ƒ/ƒ0; frictional ratio; MM; molecular mass; Rs; Stokes radius; R0; Stokes radius for a smooth and spherical particle; s; sedimentation coefficient; s20,w; sedimentation coefficient at standard

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of molecular chaperones through post-translational modifications: Decrypting the chaperone code

Keywords: Molecular chaperone; Post-translational modification; Hsp70; Hsp90; VCP;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions

Keywords: HSP90; HSP90 inhibitors; Molecular chaperone; Molecularly targeted therapy;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of the mitochondrial Hsp90 chaperone network: A novel, efficient treatment strategy for cancer?

Keywords: 17-AAG; 17-N-Allylamino-17-demethoxygeldanamycin; AMPK; AMP-activated kinase; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; CsA; Cyclosporin A; CyD; Cyclophilin-D; G-G4; Gamitrinib(s), Geldanamycin (GA), mitochondrial matrix inhibitors - Gamitrinib â€

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Hsp90-targeted miRNA-liposomal formulation for systemic antitumor effect

Keywords: Hsp90; Glucocorticoid receptor; Liposome; Akt; p53; Cancer;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Proteome of the insulin-secreting Min6 cell porosome complex: Involvement of Hsp90 in its assembly and function

Keywords: Min6 cell porosome proteome; Insulin secretion; Mass spectrometry; Hsp90;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Specificity in the actions of the UBR1 ubiquitin ligase in the degradation of nuclear receptors

Keywords: Ubiquitin ligase; Quality control; Degradation; Molecular chaperone; Hsp90; UBR1AR, androgen receptor; CHIP, C-terminal Hsp interacting protein; DMSO, dimethylsulfoxide; ER, estrogen receptor; GA, geldanamycin; GR, glucocorticoid receptor; HA, hemagglutin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

The small co-chaperone p23 overexpressing transgenic mouse

Keywords: ER, endoplasmic reticulum; pcd, programmed cell death; Tg, transgenicEndoplasmic reticulum; p23; HSP90; Caspase; Programmed cell death; Alzheimer's disease

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Biochemical characterization and cooperation with co-chaperones of heat shock protein 90 from Schizosaccharomyces pombe

Keywords: Chaperone; Hsp90; Co-chaperone; Conformational change; Schizosaccharomyces pombe

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Heat stress: A risk factor for skin carcinogenesis

Keywords: Skin cancer; Heat stress; Heat shock proteins; Heat shock response; HSP72; HSP90

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression

Keywords: PCa, prostate cancer; AR, androgen receptor; CRPC, castration-resistant prostate cancer; Hsp, heat shock proteins; DMSO, dimethyl sulfoxide; EtOH, ethanol; GA, geldanamycinAndrogen receptor (AR); Prostate cancer; Splice variants; Hsp90; FKBP52

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Conformational and functional studies of a cytosolic 90 kDa heat shock protein Hsp90 from sugarcane

Keywords: Hsp90; Sugarcane; Protein folding; Molecular chaperone; Heat shock protein; CD; circular dichroism; D; deuterium; DSS; disuccinimidyl suberate; DLS; dynamic light scattering; H; hydrogen; MS; mass spectrometry; SEC-MALS; size exclusion chromatography coup

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of atrazine and chlorpyrifos exposure on heat shock protein response in the brain of common carp (Cyprinus carpio L.)

Keywords: Common carp; HSP60; HSP70; HSP90; Atrazine; Chlorpyrifos;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Hsp90: Still a viable target in prostate cancer

Keywords: Hsp90; Inhibitors; Prostate cancer; Clinical trials

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Involvement of the 90 kDa heat shock protein during adaptation of Paracoccidioides brasiliensis to different environmental conditions

Keywords: HSP90, heat shock protein 90 kDa; aRNA, antisense RNA; ROS, reactive oxygen species; ATMT, Agrobacterium tumefaciens-mediated transformation; PCM, paracoccidioidomycosisParacoccidioides brasiliensis; Gene knock-down; HSP90; Growth rate; Viability; Oxidati

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Binding partners for curcumin in human schwannoma cells: Biologic Implications

Keywords: Hsp, Heat shock protein; PGDH, 3-phosphoglycerate dehydrogenaseCurcumin; hsp70; hsp90; D-3-phosphoglycerate dehydrogenase; Biotinylation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-tumor selectivity of a novel Tubulin and HSP90 dual-targeting inhibitor in non-small cell lung cancer models

Keywords: Anti-tumor selectivity; Promiscuous; Tubulin; HSP90; Non-small cell lung cancer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function

Keywords: Protein quality control; Sarcomere; Titin; Hsp90; Protein methylation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

An activated JAK/STAT3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma

Keywords: MM, Multiple myeloma; Hsp90, Heat shock protein 90 kD; Hsp90-Is, Hsp90 inhibitors; STAT3C, Constitutively active STAT3, 17DMAG, 17-Desmethoxy-17-N,N-dimethylaminoethylamino-geldanamycin, HClMultiple myeloma; Apoptosis; STAT3; Akt; 17DMAG; HSP90

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Leptin increases HER2 protein levels through a STAT3-mediated up-regulation of Hsp90 in breast cancer cells

Keywords: Leptin; Hsp90; HER2; Breast cancer; Tamoxifen resistance

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Gastrointestinal Stromal Tumors

Keywords: GIST; Tyrosine kinase inhibitors; SDH-deficient GIST; KIT; PDGFRA; IGF-1R; HSP90;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Dissecting the Heat Stress Response in Chlamydomonas by Pharmaceutical and RNAi Approaches Reveals Conserved and Novel Aspects

Keywords: heat shock factor; unfolded protein response; heat stress response; inhibitor feeding; Chlamydomonas reinhardtii; HSP90; HSP70; protein folding; calcium; geldanamycin; canavanine

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

An Hsp90 modulator that exhibits a unique mechanistic profile

Keywords: Hsp90; Sansalvamide A; Pull-down; Caspase 3; Heat shock proteins;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

The Hsp90 inhibitor 17-AAG represses calcium-induced cytokeratin 1 and 10 expression in HaCaT keratinocytes

Keywords: Cytokeratin 1 and 10; Involucrin; Hsp90; 17-AAG; Keratinocyte differentiation; HaCaT

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Heat shock protein 90 from neglected protozoan parasites

Keywords: Hsp90; Chaperone; Protozoan; Plasmodium; Giardia; Trans-splicing;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Methoxychalcone inhibitors of androgen receptor translocation and function

Keywords: Chalcone; Antiandrogen; Androgen receptor translocation; Prostate cancer; Hsp90;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Depression of mitochondrial metabolism by downregulation of cytoplasmic deacetylase, HDAC6

Keywords: HDAC6, histone deacetylase 6; MEF, mouse embryonic fibroblast; CS, citrate synthaseHistone deacetylase 6; Mitochondria; Succinate dehydrogenase; Respiratory complex II; Citrate synthase; Hsp90

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

Keywords: Hsp90; Chaperone; Inhibitors; Indolone; Aminoquinazoline; Quinazoline; Her2; Cancer

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Boron induced expression of some stress-related genes in tomato

Keywords: Glutathione reductase; Hsp90; Solanum lycopersicum; Boron stress; Metallothionein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Quality control and fate determination of Hsp90 client proteins

Keywords: Molecular chaperone; Ubiquitin/proteasome pathway; Quality control; Hsp90;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Expanding the cellular molecular chaperone network through the ubiquitous cochaperones

Keywords: Hsp90; p23; Cdc37; Large immunophilin; Cochaperone; Molecular chaperone;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: A necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site

Keywords: eIF3c; Hsp90; HCV IRES; 17-AAG; Translation initiation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population

Keywords: TAA, tumor-associated antigen; CSC, cancer stem-like cell; CIC, cancer-initiating cell; SP, side population; MP, main populationCancer immunotherapy; DNA vaccine; Tumor antigen; Cancer stem cell; HSP90

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor

Keywords: Hsp90; Hsp90 inhibitor; 17-DMAG; Gefitinib; EGFR mutation; EGFR-TKI; Acquired resistance

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivatives

Keywords: HSP90; Quadruplex; Promoter; Small molecule;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer

Keywords: NSCLC; Hsp90; AUY922; EGFR; EGFR-TKI; Mesothelioma;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Heat shock protein 90 is a putative therapeutic target in patients with recurrent advanced-stage ovarian carcinoma with serous effusions

Keywords: HSP90; Ovarian carcinoma; Serous effusion; Chemotherapy; Survival

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Evolution and function of diverse Hsp90 homologs and cochaperone proteins

Keywords: Hsp90; Cochaperones; Tetratricopeptide repeats; Evolution;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Hsp90 interacts with AMPK and mediates acetyl-CoA carboxylase phosphorylation

Keywords: AMPK; Hsp90; Interaction; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Conditional inactivation of replication proteins in fission yeast using hormone-binding domains

Keywords: β-estradiol; Conditional allele; GINS; Hsp90; Hormone-binding domain; Schizosaccharomyces pombe;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Destabilization of PDK1 by Hsp90 inactivation suppresses hepatitis C virus replication through inhibition of PRK2-mediated viral RNA polymerase phosphorylation

Keywords: Hsp90; heat shock protein 90; HCV; hepatitis C virus; RdRp; RNA-dependent RNA polymerase; 17-DMAG; 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin; PDK1; phosphoinositide-dependent kinase-1; PRK2; protein kinase C-related kinase 2; Hsp90 inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanisms of developmental robustness

Keywords: Systems biology; Development; Robustness; Canalization; Hsp90; miRNA; Gap genes

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and antikinetoplastid activities of 3-substituted quinolinones derivatives

Keywords: Antiprotozoal; Leishmania donovani; Trypanosoma brucei brucei; Quinolinone derivatives; HSP90

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Cloning, purification and characterization of a 90 kDa heat shock protein from Citrus sinensis (sweet orange)

Keywords: Molecular chaperones; Protein folding; Hsp90; Protein aggregation; Citrus sinensis; CD; circular dichroism; SEC-MALS; size exclusion chromatography coupled to multi-angle light scattering;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleCombination therapy for hepatocellular carcinoma: Additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib

Keywords: BCLC; Barcelona Clinic Liver Cancer; CI; confidence interval; FACS; fluorescent-activated cell sorting; HCC; hepatocellular carcinoma; HBV; hepatitis B virus; HCV; hepatitis C virus; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitor; HSP90;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Hsp90 Inhibition Overcomes HGF-Triggering Resistance to EGFR-TKIs in EGFR-Mutant Lung Cancer by Decreasing Client Protein Expression and Angiogenesis

Keywords: HGF; EGFR-TKI resistance; Hsp90; Lung cancer; EGFR mutation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A prescription for ‘stress’ – the role of Hsp90 in genome stability and cellular adaptation

Keywords: Hsp90; chaperone; cell stress; genome instability; adaptation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

UBR1 promotes protein kinase quality control and sensitizes cells to Hsp90 inhibition

Keywords: Molecular chaperone; Ubiquitin ligase; hsp90; UBR1; Quality control

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90

Keywords: Hsp90; TPR; Hybrid peptide; Molecular chaperone; Acute myeloid leukemia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه