دانلود مقالات ISI درباره Hsp90 + ترجمه فارسی

Isoform-Specific Phosphorylation in Human Hsp90β Affects Interaction with Clients and the Cochaperone Cdc37

Keywords: Hsp90; 90-kDa heat shock protein; GRLBD; glucocorticoid receptor ligand binding domain; FOA; 5-fluoroorotic acid; GFP; green fluorescent protein; PRE; pheromone response element; GRE; glucocorticoid response element; AMPPNP; adenosine 5′-(β,γ-imido)tr

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Ct shift: A novel and accurate real-time PCR quantification model for direct comparison of different nucleic acid sequences and its application for transposon quantifications

Keywords: qPCR; quantitative polymerase chain reaction; Ct; threshold cycle; ΔΔCt; comparative Ct; RT-PCR; reverse transcription PCR; PGBD3; PiggyBac derived transposon family member 3; CS; Cockayne syndrome; CSB; Cockayne syndrome B; SB; Sleeping Beauty; Rcor1;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

CTP synthase forms the cytoophidium in human hepatocellular carcinoma

Keywords: CTPS; cytidine triphosphate synthase; UTP; uridine triphosphate; ATP; adenine triphosphate; DON; 6-diazo-5-oxo-L-norleucine; DAU; deazauridine; HCC; hepatocellular carcinoma; HSP90; heatshock protein 90; MSOX; L-methionine sulfoximine; HIF1α; hypoxia-ind

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Calpain-1 resident in lipid raft/caveolin-1 membrane microdomains plays a protective role in endothelial cells

Keywords: Ca2+-dependent proteolysis; Calpain; eNOS; nNOS; HSP90; Diabetes; ZDR; Zucker Diabetic Rats; ZFR; Zucker Fatty Rats; ZLR; Zucker Lean Rats; HSP90; heat shock protein 90; nNOS; neuronal nitric oxide synthase; eNOS; endothelial nitric oxide synthase; NO; ni

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular characterization of the HSP70 and HSP90 genes in Asian clam (Corbicula fluminea) and their expression analysis during heavy metal exposure

Keywords: HSP70; heat shock protein 70; HSP90; heat shock protein 90; CfHSP70; heat shock protein 70 of Corbicula fluminea; CfHSP90; heat shock protein 90 of Corbicula fluminea; ORF; open reading frame; UTR; terminal untranslated region; MW; molecular weight; pI; i

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3

Keywords: ACK1; HSP90; Lung cancer; SIAH2; STAT1; STAT3;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

A norepinephrine-responsive miRNA directly promotes CgHSP90AA1 expression in oyster haemocytes during desiccation

Keywords: Desiccation; Norepinephrine; HSP90; miRNA-mediated gene promotion;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Single-walled carbon nanotubes (SWCNTs) inhibit heat shock protein 90 (HSP90) signaling in human lung fibroblasts and keratinocytes

Keywords: Carbon nanotube; Nanotoxicity; Single-walled; Nanomaterials; HSP90;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling

Keywords: Mitochondrial Uncoupler; Treatment; Liver Cancer; Big Data; AFP; α-fetoprotein; CDC37; cell division cycle 37; CCLE; Cancer Cell Line Encyclopedia; CMap; Connectivity Map; EGFR; epidermal growth factor receptor; FDA; Food and Drug Administration; GEO; Ge

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Nox4 regulates the eNOS uncoupling process in aging endothelial cells

Keywords: eNOS; endothelial nitric oxide synthase; HUVEC; human umbilical vein endothelial cells; NO; nitric oxide; Nox4; NADPH oxidase 4; ROS; reactive oxygen species; NAC; N-acetyl cysteine; TUDCA; tauroursodeoxycholic acid; 4-PBA; 4-phenylbutyric acid; ER; endop

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Src-family tyrosine kinases and the Ca2 + signal

Keywords: 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Different gene expression profiles between normal and thermally selected strains of rainbow trout, Oncorhynchus mykiss, as revealed by comprehensive transcriptome analysis

Keywords: AP-1; activator protein 1; BP; biological process; CC; cell component; DS; Donaldson; GO; gene ontology; HSE; heat shock element; HSP70; 70 kDa heat shock protein; HSP90; 90 kDa heat shock protein; HSPs; heat shock proteins; HT; high-temperature selecte

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Heavy ion radiobiologyThe purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining

Keywords: PU-H71; Hsp90; Heavy ion radiotherapy; Radiosensitization; DNA repair;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo

Keywords: Tyrosine kinase; HSP90; NVP-AUY922; Cytarabine; KG-1a leukemia;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperA comparative examination of cortisol effects on muscle myostatin and HSP90 gene expression in salmonids

Keywords: Stress; Growth; Myostatin; HSP90; Hormone;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of a heat shock protein 90 gene involved in resistance to temperature stress in two wing-morphs of Nilaparvata lugens (Stål)

Keywords: Nilaparvata lugens; Hsp90; RNAi; Thermotolerance; Gene expression

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNAs: New regulators of IL-22

Keywords: IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Heat shock protein 90 is essential for replication of porcine circovirus type 2 in PK-15 cells

Keywords: Porcine circovirus type 2; Hsp90; Replication; Antiviral

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Epidermolysis Bullosa Acquisita: From Pathophysiology to Novel Therapeutic Options

Keywords: Breg; immunoregulatory B cell; EBA; epidermolysis bullosa acquisita; Flii; Flightless I; Hsp90; heat shock protein 90; IVIG; intravenous immunoglobulins; MHC; major histocompatibility complex; MMP; matrix metalloproteinase; NC; noncollagenous; Th1; T help

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of pyrimidinyl acyl thioureas as novel Hsp90 inhibitors in invasive ductal breast cancer and its bone metastasis

Keywords: Pyrimidine; Thiourea; Breast cancer; Bone cancer; Hsp90; Client proteins

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The cooperative expression of Heat Shock Protein 70 KD and 90 KD gene in juvenile Larimichthys crocea under Vibrio alginolyticus stress

Keywords: Larimichthys crocea; HSP70; HSP90; Vibrio alginolyticus; Cooperative expression;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Low sequence identity but high structural and functional conservation: The case of Hsp70/Hsp90 organizing protein (Hop/Sti1) of Leishmania braziliensis

Keywords: Hop; Hsp90; TPR; Molecular chaperones; L. braziliensis; Protozoa; AUC; Analytical ultracentrifugation; CD; circular dichroism; ƒ/ƒ0; frictional ratio; MM; molecular mass; Rs; Stokes radius; R0; Stokes Radius for a smooth and spherical particle; Rg; Rad

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Subcellular localisation of Theiler's murine encephalomyelitis virus (TMEV) capsid subunit VP1 vis-á-vis host protein Hsp90

Keywords: Theiler's murine encephalomyelitis virus; VP1; Hsp90; Polyclonal antibody; Capsid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors

Keywords: Heat shock protein 90; HSP90; Hypoxia Inducible Factor-1; HIF-1; Antitumor; Deguelin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Hsp90 directly interacts, in vitro, with amyloid structures and modulates their assembly and disassembly

Keywords: Hsp90; heat shock protein 90 kDa; SEC; size-exclusion chromatography; ThT; Thioflavin T; CcN; critical concentration of nucleation; CcA; critical concentration of assembly; NTD; N-terminal domain; MD; middle domain; CTD; C-terminal domain; AUC; area unde

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5

Keywords: PRMT5; protein arginine methyltransferase 5; EGFR; epidermal growth factor receptor; TNF; tumor necrosis factor; NF-Y; nuclear factor Y; PKC; protein kinase C; Hsp90; heat shock protein 90; UPS; ubiquitin-proteasome system; CHIP; carboxyl terminus of he

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Cloning of heat shock protein genes (hsp70, hsc70 and hsp90) and their expression in response to larval diapause and thermal stress in the wheat blossom midge, Sitodiplosis mosellana

Keywords: Sitodiplosis mosellana; Hsp70; Hsc70; Hsp90; Diapause; Heat tolerance; Cold tolerance;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity

Keywords: Immunophilin; FKBP51; FKBP52; Hsp90; hTERT; Telomerase; FKBP51; FK506-binding protein of 51-kDa; FKBP52; FK506-binding protein of 52-kDa; CyP; cyclophilin; Hsp90; heat-shock protein of 90-kDa; Hsp70; heat-shock protein of 70-kDa; hTERT; human reverse tran

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90

Keywords: Hsp90; Heat shock protein 90; NTD; N-terminal domain; M-domain; middle domain; CTD; C-terminal domain; FRET; Förster resonance energy transfer; MD; molecular dynamics; LF; local flexibility; WT; wild type; GR; glucocorticoid receptor; GR-LBD; GR ligand b

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Neurobehavioral alterations plus transcriptional changes of the heat shock protein 90 and hypoxia inducible factor-1α in the crucian carp exposed to copper

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; ACS; amino cupric silver stain; Cu; copper; DIG; digoxigenin-11-dUTP; Dl; lateral part of the dorsal telencephalon; Dm; medial part of the dorsal telencephalon; HIF-1α; hypoxia inducible facto

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Hsp90: Friends, clients and natural foes

Keywords: Hsp90; Co-chaperones; Heat shock response; ATPase cycle;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor

Keywords: Antitumor peptides; Antibody CDRs; Melanoma; Cell migration; Metastasis; Hsp90; G-protein coupled receptor;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes

Keywords: ATGL; Adipose triglyceride lipase; CHOP; CCAAT-enhancer-binding protein homologous protein; CLEAR; coordinated lysosomal enhancement and regulation; CMA; chaperone mediated autophagy; CQ; chloroquine; eIF2α; eukaryotic translation initiation factor 2α;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain

Keywords: 17-AAG; 17-Allylamino-17-demethoxygeldanamycin; Cmpd; compound; CNS; central nervous system; fEPSP; evoked postsynaptic field potential; HSF1; heat-shock factor 1; HSP; heat-shock protein; Occ50; 50% occupancy; p.o.; peroral dosing; HSP70; HSP90; Occupanc

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells

Keywords: Novobiocin analog; Hsp90; Liposomes; Apoptosis; Cell cycle; Migration;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis, and anticancer activity of C8-substituted-4′-thionucleosides as potential HSP90 inhibitors

Keywords: HSP90; 4′-Thionucleosides; Structure-activity relationship; Anticancer;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) role in hematopoiesis and in hematologic diseases: A critical review

Keywords: TCCD; tetrachlorodibenzo-p-dioxin; PCDD; polychlorinated dibenzodioxins; AHR; aryl hydrocarbon receptor; Hsp90; heat shock protein 90; MAPK; mitogen-activated protein kinase; ARNT; aryl hydrocarbon receptor nuclear translocator; NF-kB; nuclear factor kB;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

HPOB, an HDAC6 inhibitor, attenuates corticosterone-induced injury in rat adrenal pheochromocytoma PC12 cells by inhibiting mitochondrial GR translocation and the intrinsic apoptosis pathway

Keywords: HDAC6; HPOB; Glucocorticoid receptor; Mitochondrial translocation; Hsp90; Cort; corticosterone; DRP1; dynamin-related protein 1; Fis1; mitochondrial fission molecule 1; GCs; glucocorticoids; GR; glucocorticoid receptor; HDACs; histone deacetylases; Hsps;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting the entry region of Hsp90's ATP binding pocket with a novel 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl amide

Keywords: Hsp90; Cancer; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

In silico identification and computational analysis of the nucleotide binding site in the C-terminal domain of Hsp90

Keywords: Hsp90; C-terminal domain; Nucleotide binding site; Molecular docking; Homology modeling;

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer TARGETases: DSB repair as a pharmacological target

Keywords: DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel

دانلود رایگان متن کامل مقاله ISI 110 صفحه سال انتشار : 2016 سفارش ترجمه

The dynamic interactome of human Aha1 upon Y223 phosphorylation

Keywords: Cancer; Hsp90; Interactome; Proteomics; Phosphorylation; Chaperones; Aha1; Co-chaperones

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy machinery in the context of mammalian mitophagy

Keywords: PINK1; PTEN-induced putative kinase 1; CCCP; carbonyl cyanide m-chlorophenylhydrazone; OMM; outer mitochondrial membrane; ATG; autophagy-related; ULK1; unc-51 like kinase 1; FIP200; focal adhesion kinase family interacting protein of 200 kDa; mTor; mecha

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of 3,5-disubstituted-4-alkynylisoxozales as a novel class of HSP90 inhibitors

Keywords: HSP90; 3,5-Disubstitute-4-alkynylisoxazole; HSP90 inhibitor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of eNOS in endothelial cells exposed to ionizing radiation involves components of the DNA damage response pathway

Keywords: Ionizing radiation; Endothelial nitric oxide synthase; ATM; HSP90; DNA damage response;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Combined inhibition of Hsp90 and heme oxygenase-1 induces apoptosis and endoplasmic reticulum stress in melanoma

Keywords: Heme oxygenase; Hsp90; ER stress; Melanoma; Apoptosis; Cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular docking study, synthesis and biological evaluation of Mannich bases as Hsp90 inhibitors

Keywords: Hsp90; Mannich base; Docking;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Genetic responses of the marine copepod Acartia tonsa (Dana) to heat shock and epibiont infestation

Keywords: Acartia tonsa; β-Actin; Efa-1α; Epibiont infestation; Ferritin; Heat shock; Hsp70; Hsp90; Gene expression

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

UNC45A localizes to centrosomes and regulates cancer cell proliferation through ChK1 activation

Keywords: Tumorigenesis; UNC45A; Hsp90; Chaperone; ChK1; Centrosome;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Association of heat shock protein 90 with the developmental competence of immature oocytes following Cryotop and solid surface vitrification in yaks (Bos grunniens)

Keywords: Yak; HSP90; Developmental competence; Immature oocytes; Vitrification;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه