Keywords: انیدراز کربن انسانی انسان; Human carbonic anhydrase; Enzyme inhibitors; Sulfonamides
مقالات ISI انیدراز کربن انسانی انسان (ترجمه نشده)
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Keywords: انیدراز کربن انسانی انسان; ADP; adenosine diphosphate; APH; aminoglycoside phosphotransferase (3â²)-IIIa; BSA; bovine serum albumin; Cc; iso-1-ferricytochrome c; CcP; ferricytochrome c peroxidase; CD; circular dichroism; ConA; concanavalin A; ÎCp; change in heat capacity; ÎG; Gi
Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors
Keywords: انیدراز کربن انسانی انسان; Carbonic anhydrase inhibitors; Isoforms I, II, IV, IX; Benzenesulfonamide; 1,2,3-Triazole; CA; Carbonic anhydrase; hCA; human carbonic anhydrase; CAIs; Carbonic anhydrase inhibitors; AAZ; Acetazolamide; Ki; Inhibition constant; nM; nanomolar; μM; micromo
Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide
Keywords: انیدراز کربن انسانی انسان; Human Carbonic Anhydrase; Acetazolamide; Recognition; Surface plasmon resonance; Tumor;
Synthesis and evaluation of new benzodioxole-based dithiocarbamate derivatives as potential anticancer agents and hCA-I and hCA-II inhibitors
Keywords: انیدراز کربن انسانی انسان; Dithiocarbamate; Benzodioxole; Cancer; Human carbonic anhydrase;
Immobilization and characterization of human carbonic anhydrase I on amine functionalized magnetic nanoparticles
Keywords: انیدراز کربن انسانی انسان; Human carbonic anhydrase; APTES; Magnetic nanoparticles; Immobilization; TEOS;
Molecular dynamics study of human carbonic anhydrase II in complex with Zn2+ and acetazolamide on the basis of all-atom force field simulations
Keywords: انیدراز کربن انسانی انسان; Metalloenzyme; Human carbonic anhydrase; Protein-ligand interaction; Protein-metal interaction; Free energy of binding;
Optimization of allosteric MEK inhibitors. Part 2: Taming the sulfamide group balances compound distribution properties
Keywords: انیدراز کربن انسانی انسان; Allosteric MEK inhibitor; Oncology; Structure-based drug design; Human carbonic anhydrase; Blood–plasma ratio
Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII
Keywords: انیدراز کربن انسانی انسان; CA; carbonic anhydrase; hCA; human carbonic anhydrase; Quinacrine; (RS)-Nâ²-(6-Chloro-2-methoxy-acridin-9-yl)-N,N-diethylpentane-1,4-diamine; Proflavine; acridine-3,6-di-amine; Amsacrine; N-(4-(acridin-9-ylamino)-3-methoxyphenyl)methanesulfonamide; IR; i
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms
Keywords: انیدراز کربن انسانی انسان; Human carbonic anhydrase; Isoquinoline; Quinoline; X-ray; Molecular docking; AAZ; acetazolamide; CAs; carbonic anhydrases; HBTU; N,N,Nâ²,Nâ²-tetramethyl-O-(1H-benzotriazol-1-yl)uranium hexafluorophosphate; TMP; topiramate;
Enhancement of thermal reversibility and stability of human carbonic anhydrase II by mesoporous nanoparticles
Keywords: انیدراز کربن انسانی انسان; Aminopropyl functionalized PEGylated mesoporous silica nanoparticles; Human carbonic anhydrase; Thermal reversibility and stability;
Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies
Keywords: انیدراز کربن انسانی انسان; Coumarins; Anticancer; Synthesis; Targets; SAR; IC50; ARI; aromatase inhibitor; CAM; choriallanotoic membrane; CDC; cell cycle division protein; CDK2; cyclin dependent kinase 2; CDKN1A; cyclin-dependent kinase inhibitor 1A; CYP; cytochromes P450; DDIT4; D
Design and synthesis of azobenzene template based sulfonamide for capture of HCAII: dependence of efficiency on E-Z geometry
Keywords: انیدراز کربن انسانی انسان; Azobenzene; Human Carbonic Anhydrase; Protein; Capture; MALDI; Photoisomerization;
Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties
Keywords: انیدراز کربن انسانی انسان; CA; carbonic anhydrase; hCA; human carbonic anhydrase; CAI; carbonic anhydrase inhibitor; SAR; structure-activity relationship; Zn; zinc; AZM; acetazolamide; MZA; methazolamide; EZA; ethoxzolamide; DCP; dibromophenamide; DZA; dorzolamide; BRZ; brinzolam
Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety
Keywords: انیدراز کربن انسانی انسان; CA; carbonic anhydrase; hCA; human carbonic anhydrase; CAI; carbonic anhydrase inhibitor; SAR; structure-activity relationship; Zn; zinc; AZM; acetazolamide; MZA; methazolamide; EZA; ethoxzolamide; DCP; dibromophenamide; DZA; dorzolamide; BRZ; brinzolam
Appraisal of sildenafil binding on the structure and promiscuous esterase activity of native and histidine-modified forms of carbonic anhydrase II
Keywords: انیدراز کربن انسانی انسان; hCA; human carbonic anhydrase; PDE5; phosphodiesterase-5; CD; circular dichroism; PSH; protein surface hydrophobicity; ANS; 1,8-anilinonaphtalene sulfonate; PDB; protein data bank; ED; erectile dysfunction; CAIs; CA inhibitors; DEPC; diethyl pyrocarbonate
QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII
Keywords: انیدراز کربن انسانی انسان; QSAR; Human carbonic anhydrase; Sulfamates; Sulfamides; PRECLAV
Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore
Keywords: انیدراز کربن انسانی انسان; Human carbonic anhydrase; CA inhibitors; Virtual screening
Theoretical improvement of the specific inhibitor of human carbonic anhydrase VII
Keywords: انیدراز کربن انسانی انسان; Human carbonic anhydrase; Isozyme-specific inhibitor; Arylsulfonamides; Homology modeling; Molecular docking
Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding
Keywords: انیدراز کربن انسانی انسان; Protein folding; Prion; Ribosome; Antiprion drugs; Carbonic anhydrase; RFM; Ribosomal folding modulator; 6AP; 6-aminophenanthridine; GA; Guanabenz; HCA; human carbonic anhydrase; rRNA; ribosomal RNA;
Reshaping the folding energy landscape of human carbonic anhydrase II by a single point genetic mutation Pro237His
Keywords: انیدراز کربن انسانی انسان; ANS; 8-anilino-1-naphthalene sulfonic acid; CA; carbonic anhydrase; GdnHCl; guanidine hydrochloride; HCA; human carbonic anhydrase; CD; circular dichroism; I320; intrinsic fluorescence intensity at 320Â nm; I365; intrinsic fluorescence intensity at 365Â n