Keywords: هیپرفورین; Hypericum perforatum; Hyperforin; Formulations; Stabilization; Pharmacological profile; In vitro cultures; Root cultures; Gene identification; Heterologous production; Hypericin;
مقالات ISI هیپرفورین (ترجمه نشده)
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Keywords: هیپرفورین; Early separation from parents; Anxiety; Depression; Hyperforin
Downstream processing of hyperforin from Hypericum perforatum root cultures
Keywords: هیپرفورین; Hyperforin; Hypericum perforatum; Root cultures; Extraction; Hyperforin (PubChem CID 441298);
Phytochemical profiles, phototoxic and antioxidant properties of eleven Hypericum species - A comparative study
Keywords: هیپرفورین; Hypericum species (Clusiaceae Lindl.); Phototoxicity; Polyphenols; Hypericin; Hyperforin; Antioxidants; SJW; St. John's wort; EMEA; European Medicine Agency; WHO; World Health Organization; PTFE; Polytetrafluoroethylene; DPPH; di(phenyl)-(2,4,6-trinitroph
Anti-proliferative and anti-migratory effects of hyperforin in 2D and 3D artificial constructs of human dermal fibroblasts - A new option for hypertrophic scar treatment?
Keywords: هیپرفورین; HYP; hyperforin; Il-8; interleukine 8; HDF; human dermal fibroblasts; DMSO; dimethyl sulfoxide; AD construct; artificial dermal construct; Hyperforin; Human dermal fibroblast; Migration; Contraction; Skin; Viability assay; Live-dead cell staining;
Stabilization of hyperforin dicyclohexylammonium salt with dissolved albumin and albumin nanoparticles for studying hyperforin effects on 2D cultivation of keratinocytes in vitro
Keywords: هیپرفورین; DMEM; Dulbecco's Modified Eagle Medium; KGM; keratinocyte growth medium; HYP; hyperforin; HYP-DCHA; hyperforin dicyclohexylammonium; FCS; fetal calf serum; BSA; bovine serum albumine; ANP; albumin nanoparticle; s.d.; standard deviation; w/o; without; PDI;
Hyperforin protects against acute cerebral ischemic injury through inhibition of interleukin-17A-mediated microglial activation
Keywords: هیپرفورین; Cerebral ischemia; Hyperforin; IL-17A; Microglia; Neuroprotection;
Comparison of chemical composition of Hypericum perforatum and H. maculatum in Estonia
Keywords: هیپرفورین; Hypericum perforatum; Hypericum maculatum; Metabolomics; Hypericin; Hyperforin; HPLCâMS/MS; PCA;
Hyperforin attenuates aluminum-induced Aβ production and Tau phosphorylation via regulating Akt/GSK-3β signaling pathway in PC12 cells
Keywords: هیپرفورین; Hyperforin; Aluminum maltolate; β-Amyloid; Tau; Akt/GSK-3β; Signaling pathway;
Modulation of anthraquinones and phloroglucinols biosynthesis in Hypericum spp. by cryogenic treatment
Keywords: هیپرفورین; Hypericins; Hyperforin; H. perforatum; H. rumeliacum; H. tetrapterum; Cold stress;
Review articleClinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Keywords: هیپرفورین; Depression; Complementary and alternative medicine; St John's wort; Hypericin; Hyperforin; Antidepressant;
Effects of Hypericum perforatum extract and its main bioactive compounds on the cytotoxicity and expression of CYP1A2 and CYP2D6 in hepatic cells
Keywords: هیپرفورین; Hypericum perforatum; Hypericin; Hyperforin; CYP1A2; CYP2D6; Hepatic cells; Herb-drug interactions
Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells
Keywords: هیپرفورین; Hypericin; Hyperforin; Aristoforin; Drug efflux; CYP3A4; Drug resistance
Research reportHyperforin promotes post-stroke functional recovery through interleukin (IL)â17A-mediated angiogenesis
Keywords: هیپرفورین; Angiogenesis; Hyperforin; Il-17a; Ischemic stroke; Vegf;
DNA-protective activities of hyperforin and aristoforin
Keywords: هیپرفورین; Hyperforin; Aristoforin; DNA-topology assay; DPPH/OH scavenging activity; Reducing power assay; DNA unwinding assay
The change of spatial cognition ability in depression rat model and the possible association with down-regulated protein expression of TRPC6
Keywords: هیپرفورین; TRPC6; Depression; Hyperforin; Synaptic plasticity; Dendrite; Spine
Lipid nanocapsules containing the non-ionic surfactant Solutol HS15 inhibit the transport of calcium through hyperforin-activated channels in neuronal cells
Keywords: هیپرفورین; Solutol HS15; Nanoparticles; Calcium channels; Store-operated channels; Hyperforin; Lipid nanocapsules;
Effets cellulaires et moléculaires de l'hyperforine, un antidépresseur végétal : revue de la littérature
Keywords: هیپرفورین; Antidépresseur; Cerveau; Hyperforine; Calcium; Zinc; Canaux TRPC6; Hyperforin; Antidepressant; Brain; Calcium; Zinc; TRPC6 channels;
St. John's Wort seed and feverfew flower extracts relieve painful diabetic neuropathy in a rat model of diabetes
Keywords: هیپرفورین; St. John's Wort; Feverfew; Painful diabetic neuropathy; Hypericin; Hyperforin; Parthenolide
Stereoselective total synthesis of (±)-hyperforin via intramolecular cyclopropanation
Keywords: هیپرفورین; Cyclopropanation; Hyperforin; Natural product; Stereoselectivity; Total synthesis;
Profile of antimicrobial potential of fifteen Hypericum species from Portugal
Keywords: هیپرفورین; Antibacterial activity; Antimycobacterial activity; Hypericaceae; Hypericum species; Agrobacterium tumefasciens; Multidrug-resistant Mycobacterium tuberculosis; Mycobacterium species; Hyperforin; Hypericin; Pseudohypericin; Staphylococcus aureus
St. John's Wort inhibits insulin signaling in murine and human adipocytes
Keywords: هیپرفورین; SJW, St. John's Wort; HI, hypericin; HF, hyperforin; T2DM, Type 2 diabetes mellitus; IRS-1, insulin receptor substrate 1; IRS-1 pY896, IRS-1 phosphorylated at tyrosine 896Fat cell; Insulin action; Botanicals; Hypericin; Hyperforin
The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells
Keywords: هیپرفورین; PDT; Hypericin; Hyperforin; Aristoforin
Hyperforin changes the zinc-storage capacities of brain cells
Keywords: هیپرفورین; Hyperforin; Calcium; Zinc; Neurones; Calcium channels; Calcium stores; Mice;
Isolation and purification of series bioactive components from Hypericum perforatum L. by counter-current chromatography
Keywords: هیپرفورین; Counter-current chromatography; Hypericum perforatum L.; Hyperforin; Hypericin; Rutin; Hyperoside
Synthetic efforts toward [3.3.1] bridged bicyclic phloroglucinol natural products
Keywords: هیپرفورین; Hyperforin; Garsubellin A; Clusianone; Nemorosone; Guttiferone;
Determination of hypericin and hyperforin content in selected Jordanian Hypericum species
Keywords: هیپرفورین; Hypericin; Hyperforin; Hypericum; Standardization; HPLC
Store-depletion and hyperforin activate distinct types of Ca2+-conducting channels in cortical neurons
Keywords: هیپرفورین; Mice; Brain; Cortex; Neurons; Calcium channels; Calcium stores; TRPC; Hyperforin; TRPC3; TRPC6;
A Prolonged Protein Kinase C-Mediated, Opioid-Related Antinociceptive Effect of St John's Wort in Mice
Keywords: هیپرفورین; Hypericum perforatum; St. John's Wort; analgesia; antinociception; hypericin; hyperforin
A review of the antibacterial activity of Hypericum perforatum L.
Keywords: هیپرفورین; Hypericum perforatum; Hypericaceae; Antimicrobial activity; Hyperforin; Hypericin
Hyperforin induces Ca2+-independent arachidonic acid release in human platelets by facilitating cytosolic phospholipase A2 activation through select phospholipid interactions
Keywords: هیپرفورین; Phospholipases A2; Arachidonic acid; Platelets; Hyperforin; Calcium; Phosphorylation
The PXR is a drug target for chronic inflammatory liver disease
Keywords: هیپرفورین; ALT; alanine aminotransferase; CsA; cyclosporin A; GT; gliotoxin; GAPDH; glyceradehyde 3 phosphate dehydrogenase; HYP; hyperforin; IKK2-In; IκB kinase 2 inhibitor; LPS; lipopolysaccharide; METYR; metyrapone; MTS; ([3-(4,5-dimethylthiazol-2-yl)-5-(3-carbo
Involvement of serotoninergic 5-HT1A/2A, alpha-adrenergic and dopaminergic D1 receptors in St. John's wort-induced prepulse inhibition deficit: A possible role of hyperforin
Keywords: هیپرفورین; St. John's wort; Prepulse inhibition (PPI); Serotonin; Noradrenaline; Dopamine; Hyperforin
Proapoptotic and prepulse inhibition (PPI) disrupting effects of Hypericum perforatum in rats
Keywords: هیپرفورین; St. John's wort; Prepulse inhibition (PPI); Antiamnestic; Hyperforin; Apoptosis;
Mechanisms of Hyperforin as an anti-angiogenic angioprevention agent
Keywords: هیپرفورین; Hyperforin; Angiogenesis; Inflammation; Neutrophils; Monocytes; Endothelial cells; Chemoprevention;
Extraction of hyperforin and adhyperforin from St. John's Wort (Hypericum perforatum L.) by supercritical carbon dioxide
Keywords: هیپرفورین; Hypericum perforatum L.; St. John's Wort; Supercritical fluid extraction; Hyperforin; Adhyperforin
Pseudohypericin and hyperforin in two Turkish Hypericum species: Variation among plant parts and phenological stages
Keywords: هیپرفورین; HPLC; Hyperforin; Hypericum origanifolium; Hypericum perfoliatum; Ontogenetic and morphogenetic variation; Pseudohypericin
Molecular cloning and tissue-specific expression of two cDNAs encoding polyketide synthases from Hypericum perforatum
Keywords: هیپرفورین; Biosynthesis; Hyperforin; Hypericin; Polyketide synthase; St. John's wort (Hypericum perforatum)BPS, benzophenone synthase; CHS, chalcone synthase; DAD, diode array detector; HPLC, high-performance liquid chromatography; ORF, open reading frame; PCR, poly
A new approach for the construction of a highly congested bicyclic system in polycyclic polyprenylated acylphloroglucinols (PPAPs)
Keywords: هیپرفورین; Polycyclic polyprenylated acylphloroglucinols (PPAPs); Garsubellin A; Hyperforin; Bicyclo[3.3.1]nonanone core; Claisen rearrangement; Intramolecular aldol reaction;
Differential accumulation of hyperforin and secohyperforin in Hypericum perforatum tissue cultures
Keywords: هیپرفورین; BAP; N6-benzylaminopurine; DAD; diode array detector; LC; liquid chromatography; MS; mass spectrometry; NAA; naphthalene-1-acetic acid; NMR; nuclear magnetic resonance; Hypericum perforatum; Clusiaceae; In vitro cultures; Hyperforin; Secohyperforin; HPLC-
Biosynthesis of hyperforin and adhyperforin from amino acid precursors in shoot cultures of Hypericum perforatum
Keywords: هیپرفورین; Hypericum perforatum; Biosynthesis; Shoot culture; Adhyperforin; Hyperforin; Isoleucine; Threonine; Valine;
Phytochemical and physiological changes in the leaves of St. John's wort plants under a water stress condition
Keywords: هیپرفورین; Controlled environment; Hypericin; Hyperforin; Photosynthetic efficiency; Pseudohypericin; Secondary metabolite; St. John's wort; Water stress
Matrix proteases, green tea, and St. John's wort: Biomedical research catches up with folk medicine
Keywords: هیپرفورین; Matrix-proteases; Green tea; EGCG; Hypericum sp; Hyperforin
Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS
Keywords: هیپرفورین; LC; liquid chromatography; NMR; nuclear magnetic resonance; SPE; solid-phase extraction; MS; mass spectrometry; ESI; electrospray ionization; DAD; diode array detector; Hypericum perforatum; LC/SPE/NMR; Dereplication; Hyperforin; Hyperfirin; Flavonoids;
Hyperforin
Keywords: هیپرفورین; Hyperforin; Hypericum perforatum; Clusiaceae; Structure; Pharmacology; Biosynthesis;
Variation in concentrations of major bioactive compounds of St. John's wort: Effects of harvesting time, temperature and germplasm
Keywords: هیپرفورین; Controlled environment; Hypericin; Pseudohypericin; Hyperforin; Hypericum perforatum L;
Hyperforin and its analogues inhibit CYP3A4 enzyme activity
Keywords: هیپرفورین; St. John's wort; Acylphloroglucinols; Hyperforin; Furohyperforin; Furoadhyperforin; NMR; MS and CYP3A4 enzyme;
High-performance liquid chromatography measurement of hyperforin and its reduced derivatives in rodent plasma
Keywords: هیپرفورین; Hyperforin; Octahydrohyperforin; Tetrahydrohyperforin; Pharmacokinetic; Rodents;
Temperature stress can alter the photosynthetic efficiency and secondary metabolite concentrations in St. John's wort
Keywords: هیپرفورین; Controlled environment; Hypericin; Hyperforin; Pseudohypericin; Secondary metabolite; St. John's wort; Temperature stress;
Relationships between net photosynthetic rate and secondary metabolite contents in St. John's wort
Keywords: هیپرفورین; Controlled environment; Hyperforin; Hypericin; Hypericum perforatum L.; Net photosynthetic rate; Pseudohypericin;