دانلود مقالات ISI درباره Igf-1R + ترجمه فارسی

Anaplastic lymphoma kinase (ALK) inhibitors in the treatment of ALK-driven lung cancers

Keywords: Alectinib: (PubMED CID: 49806720); Brigatinib: (PubMED CID: 68165256); Ceritinib: (PubMED CID: 57379345); Crizotinib (PubMED CID: 11626560); Entrectinib: (PubMED CID: 25141092); Lorlatinib: (PubMed CID: 71731823); ALK+-NSCLC; ALK-positive non-small cell l

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Hepatic IGF-1R overexpression combined with the activation of GSK-3β and FOXO3a in the development of liver cirrhosis

Keywords: Liver cirrhosis; IGF-1; IGF-1R; AKT; GSK-3β; FoxO3a

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Crk II silencing down-regulates IGF-IR and inhibits migration and invasion of prostate cancer cells

Keywords: Crk II; Prostate cancer; IGF-1R;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Mutation R273H confers p53 a stimulating effect on the IGF-1R-AKT pathway via miR-30a suppression in breast cancer

Keywords: p53R273H; miR-30a; IGF-1R; AKT

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of the Let-7 Family MicroRNAs Induces Cardioprotection Against Ischemia-Reperfusion Injury in Diabetic Rats

Keywords: AAR; area at risk; antimiR; antimicroRNA; C; control; DR; diabetic rat; GLUT4; glucose transporter type 4; IGF-1R; insulinlike growth factor-1 receptor; InsR; insulin receptor; IS; infarct size; L; lentivirus vectors with let-7 antimiR; LY; LY294002; miRN

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNAs: New regulators of IL-22

Keywords: IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The role of the IGF-1 Ec in myoskeletal system and osteosarcoma pathophysiology

Keywords: IGF-1; Osteosarcoma; IGF-1R; IGF-1Ec; Ec peptide; Bone; Muscle repair;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Ewing sarcoma: The clinical relevance of the insulin-like growth factor 1 and the poly-ADP-ribose-polymerase pathway

Keywords: Ewing sarcoma; IGF-1R; PARP pathway; Bone tumour; Soft tissue tumour; Sarcoma;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Insulin-like growth factor-1 receptor regulates repair of ultraviolet B-induced DNA damage in human keratinocytes in vivo

Keywords: IGF-1R; NER; Keratinocyte; UVB; Xenograft; IGF-1; insulin-like growth factor-1; IGF-1R; insulin-like growth factor-1 receptor; UVB; ultraviolet B; NMSC; non-melanoma skin cancer; SCC; squamous cell carcinoma; NER; nucleotide excision repair; TD; thymine d

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Connexin 30 downregulates Insulin-like growth factor receptor-1, abolishes Erk and potentiates effects of an IGF-R inhibitor in a glioma cell line

Keywords: Connexin30; Glioma; C6 cells; IGF-1R; Picropodophyllin; Cell migration

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways

Keywords: miR-122; IGF-1R; Sorafenib; Drug resistance; Hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleHepatitis B virus-human chimeric transcript HBx-LINE1 promotes hepatic injury via sequestering cellular microRNA-122

Keywords: EMT; epithelial-mesenchymal transition; GSK-3β; glycogen synthase kinase-3β; HBV; hepatitis B virus; HBx-LINE1; hybrid RNA transcript of the human LINE1 and the HBV-encoded X gene; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IGF-1R; insulin g

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNAs associated with the pathogenesis of multiple sclerosis

Keywords: BBB; blood-brain barrier; BMI1; B lymphoma Mo-MLV insertion region 1 homolog; CAPS-3; caspase-3; CEBPB; CCAAT/enhancer-binding protein beta; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; GA; Glatiramer acetate; HIF-1; hypo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Relative expression of the p75 neurotrophin receptor, tyrosine receptor kinase A, and insulin receptor in SH-SY5Y neuroblastoma cells and hippocampi from Alzheimer's disease patients

Keywords: Alzheimer disease; Insulin-like growth factor-1 receptor; Insulin receptor; PSD95; p75 neurotrophin receptor; tyrosine receptor kinase-A; AD; Alzheimer's disease; FBS; fetal bovine serum; HMW; high molecular weight; IGF-1R; insulin-like growth factor-1

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Unravelling exemestane: From biology to clinical prospects

Keywords: AI(s); aromatase inhibitor (s); AKT; protein kinase B; AREG; amphiregulin; BMD; bone mineral density; CYP; cytochrome P450; DHEAS; dehydroepiandrosterone sulfate; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EMA; European Medicine

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

miR-99b suppresses IGF-1R expression and contributes to inhibition of cell proliferation in human epidermal keratinocytes

Keywords: CA, condyloma acuminatum; HPV, human papillomavirus; miRNAs, microRNAs; IGF-1R, insulin-like growth factor-1 receptor; qRT-PCR, quantitative real-time PCR analysis; p-AKT, phosphorylated AKT1Condyloma acuminatum; miR-99b; IGF-1R; PI3K-AKT; Proliferation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

AKT inactivation causes persistent drug tolerance to EGFR inhibitors

Keywords: SCLC; small cell lung cancer; NSCLC; non-small-cell lung cancer; TKIs; tyrosine kinase inhibitors; RTK; receptor tyrosine kinase; EGFR; epidermal growth factor receptor; IGF-1R; insulin-like growth factor 1 receptor; FGFR1; fibroblast growth factor recept

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

NEDD4 ubiquitin ligase is a putative oncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signaling

Keywords: Nedd4; IGF-1R; Endometrial cancer; PI3K

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Expression of insulin-like growth factor 1 receptor (IGF-1R) predicts poor responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer patients harboring activating EGFR mutations

Keywords: IGF-1R; EGFR mutation; TKI; DM; Non-small cell lung cancer; Progression-free survival

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Expression and clinical significance of epidermal growth factor receptor and insulin-like growth factor receptor 1 in patients with ampullary adenocarcinoma

Keywords: Ampullary adenocarcinoma; EGFR; IGF-1R; Survival; Cyclin D1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of the insulin-like growth factor 1 receptor by CHM-1 blocks proliferation of glioblastoma multiforme cells

Keywords: EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor receptor; GBM; glioblastoma multiforme; IGF-1R; insulin-like growth factor-1 receptor; IR; insulin receptor; PDGFR; platelet-derived growth factor receptor; PI3K; phosphatidylinositol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

NEDD4: The founding member of a family of ubiquitin-protein ligases

Keywords: RING; Really Interesting New Gene; HECT; Homologous to E6-AP C-Terminus; Ndfip1; Nedd4 family interacting protein 1; AMPARs; alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptors; EGFR; epidermal growth factor receptor; FGFR1; Fibroblast gro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro

Keywords: Res; resveratrol; Mdr1; multidrug resistance 1; Pept1; peptide transporter 1; Mrp2; multidrug resistance-associated protein 2; IGF-1R; insulin-like growth factor 1 receptor; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; ABC; ATP-bindi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Dual treatments targeting IGF-1R, PI3K, mTORC or MEK synergize to inhibit cell growth, induce apoptosis, and arrest cell cycle at G1 phase in MDA-MB-231 cell line

Keywords: Triple-negative breast cancer; IGF-1R; PI3K; mTORC; MEK; Synergism

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Serum concentrations of insulin-like growth factor-1, members of the TGF-beta superfamily and follistatin do not reflect different stages of dynapenia and sarcopenia in elderly women

Keywords: BIA; bioelectric impedance analysis; BMI; body mass index; BMP; bone morphogenic protein; DXA; dual-energy X-ray absorptiometry; EWGSOP; European Working Group on Sarcopenia in Older People; FGF; fibroblast growth factor; GDF-8; growth and differentiation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?

Keywords: IGF-1R; RTK; GPCR; beta-Arrestin; GRK; Biased signalling; Cancer; Ubiquitination;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

β-Arrestin-1 protects against endoplasmic reticulum stress/p53-upregulated modulator of apoptosis-mediated apoptosis via repressing p-p65/inducible nitric oxide synthase in portal hypertensive gastropathy

Keywords: PHG; portal hypertensive gastropathy; PVL; partial portal vein ligation; SO; sham operation; PUMA; p53-upregulated modulator of apoptosis; ER; endoplasmic reticulum; GPCR; G-protein-coupled receptors; iNOS; inducible nitric oxide synthase; NF-κB; nuclear

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2015 سفارش ترجمه

Maternal exposure to bisphenol A may increase the risks of Parkinson's disease through down-regulation of fetal IGF-1 expression

Keywords: AMY; amygdala; AFP; alpha fetoglobulin; AKT; protein kinase B; BPA; bisphenol A; DA; dopamine; 6-OHDA; 6-OH-dopamine; DOPAC; dihydroxyphenylacetic acid; EB; embryoid body; EDC; environmental endocrine disruptors; ESCs; embryonic stem cells; FACS; fluoresc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Organelle communication: Signaling crossroads between homeostasis and disease

Keywords: Organelles; Endoplasmic reticulum; Mitochondria; Calcium signaling; BNIP1; BCL2/adenovirus E1B interacting protein 1; Ca2+; calcium; CERT; ceramide transfer protein; CMT2A; Charcot-Marie-Tooth type 2A; Δψmt; mitochondrial transmembrane potential; Dr

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleA phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma

Keywords: IgG1; Immunoglobulin 1; IGF-1R; Insulin growth factor 1 receptor; IGF-1; Insulin growth factor 1; MAP; Mitogen activated protein; ADCC; Antibody-dependent complement-mediated cytotoxicity; CDC; Complement-dependent cytotoxicity; IGF-2; Insulin growth fact

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Thorium induced cytoproliferative effect in human liver cell HepG2: Role of insulin-like growth factor 1 receptor and downstream signaling

Keywords: Cytoproliferative effect; Thorium; IGF-1R; Akt and MAPK; Cyclin-E

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Glargine metabolism over 24 h following its subcutaneous injection in patients with type 2 diabetes mellitus: A dose–response study

Keywords: Glargine; Pharmacokinetics and pharmacodynamics; Insulin glargine metabolites; IGF-1R; Cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

miR-223: An inflammatory oncomiR enters the cardiovascular field

Keywords: AAA; Abdominal Aortic Aneurysm; AML; Acute Myeloid Leukemia; Apo-E KO; Apolipoprotein-E Knock-Out; C/EBP; CCAAT-Enhancer-Binding Proteins; CKD; Chronic Kidney Disease; D-HF; Diabetic Heart-Failure; DMD; Duchenne Muscular Dystrophy; E2F1; E2F transcription

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer

Keywords: IGF-1R; VEGF-A; Hsp90 inhibition; Triple negative breast cancer; Biomarker; Zirconium-89; PET;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of SOD2 and β-arrestin1 by interleukin-6 contributes to the increase of IGF-1R expression in docetaxel resistant prostate cancer cells

Keywords: SOD2; Beta-arrestin1; IGF-1R; Drug resistance; Prostate cancer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Physiological cardiac hypertrophy: Critical role of AKT in the prevention of NHE-1 hyperactivity

Keywords: Sed; sedentary, not-trained rats; Swim; swim-trained rats; CH; cardiac hypertrophy; NHE-1; Na +/H + exchanger isoform 1; ERK1/2; extracellular signal-regulated kinase 1 and 2; PI3K; phosphatidylinositol 3-kinase; p90RSK; 90 kDa ribosomal S6 protein ki

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

New insights into IGF-1 signaling in the heart

Keywords: IGF-1R; inter-organelle communication; calcium; cardiac progenitor stem cells

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Prevention of BMS-777607-induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics

Keywords: Breast cancer; Receptor tyrosine kinase; Small molecule inhibitor; Senescence; Polyploidy; mTOR signaling; Chemosensitivity; AXL; Greek word anexelekto; BCR; breakpoint cluster region; BRAF; B-Rapidly Accelerated Fibrosarcoma; DAPI; 4′,6′-diamidino-2-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and in vitro evaluation of [18F]BMS-754807: A potential PET ligand for IGF-1R

Keywords: IGF-1R; Radiotracer; PET; Phosphor imaging;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

IGF-1R and ErbB3/HER3 contribute to enhanced proliferation and carcinogenesis in trastuzumab-resistant ovarian cancer model

Keywords: ErbB3/HER3; IGF-1R; Trastuzumab; Drug resistance; Ovarian cancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Resveratrol regulates the cell viability promoted by 17β-estradiol or bisphenol A via down-regulation of the cross-talk between estrogen receptor α and insulin growth factor-1 receptor in BG-1 ovarian cancer cells

Keywords: Resveratrol; IGF-1R; ERα; Cell proliferation; Endocrine disrupting chemicals;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; 4EBP1; eukaryotic translation initiation factor 4E (eIF-4E)-binding protein-1; FOXO; Forkhead box-O class transcription factors; FMRP; Fragile-X mental retardation protein; GSK3β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Combination of bendamustine and entinostat synergistically inhibits proliferation of multiple myeloma cells via induction of apoptosis and DNA damage response

Keywords: MM; Multiple myeloma; CLL; chronic lymphocytic leukemia; HDAC; histone deacetylase; HDACi; Inhibitor of HDAC; HAT; Histone acetyltransferase; PARP; poly(ADP-ribose) polymerase; ELISA; enzyme-linked immunosorbent assay; PAGE; polyacrylamide gel electrophor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Demonstration of dose dependent cytotoxic activity in SW480 colon cancer cells by 177Lu-labeled siRNA targeting IGF-1R

Keywords: IGF-1R; siRNA; 177Lu; Colon cancer; Cellular uptake; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A dose finding, safety and pharmacokinetic study of AVE1642, an anti-insulin-like growth factor-1 receptor (IGF-1R/CD221) monoclonal antibody, administered as a single agent and in combination with docetaxel in patients with advanced solid tumours

Keywords: IGF-1R; Monoclonal antibody; Sarcoma; Breast cancer; IGF-1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Lipid raft-regulated IGF-1R activation antagonizes TRAIL-induced apoptosis in gastric cancer cells

Keywords: TRAIL; IGF-1R; Lipid raft; Cbl-b;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Anticancer effect of genistein on BG-1 ovarian cancer growth induced by 17 β-estradiol or bisphenol A via the suppression of the crosstalk between estrogen receptor alpha and insulin-like growth factor-1 receptor signaling pathways

Keywords: Genistein; Bisphenol A; BG-1 ovarian cancer cells; IGF-1R; pIRS-1; pAkt;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular events on tooth socket healing in diabetic rabbits

Keywords: TGFβ-3; BMP-4; IGF-1R; VEGF

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8

Keywords: FOXO1; IGF-1R; SAMP8; Antioxidant enzyme; Longevity; Senescence

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The strength of small: Improved targeting of Insulin-like Growth Factor-1 Receptor (IGF-1R) with F(ab′)2-R1507 fragments in Ewing sarcomas

Keywords: IGF-1R; F(ab′)2; R1507; Ewing sarcoma; Immuno-SPECT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه