دانلود مقالات ISI درباره Igf-1R + ترجمه فارسی

The long road to colorectal cancer therapy: Searching for the right signals

Keywords: Colorectal cancer; Signaling pathways; Biomarkers; Monoclonal antibodies; Tyrosine kinase inhibitors; IGF-1R; c-MET; Wnt signaling; Hedgehog signaling; Src family

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Tissue selectivity and potential clinical applications of trenbolone (17β-hydroxyestra-4,9,11-trien-3-one): A potent anabolic steroid with reduced androgenic and estrogenic activity

Keywords: 17 β-TBOH; trenbolone; 17 α-TBOH; epitrenbolone; 17β-E2; estradiol; AR; androgen receptor; Akt; serine/threonine-specific kinase family; ACTH; adrenocorticotropic hormone; BMD; bone mineral density; Ca2+; calcium; CSA; cross-sectional area; DHT; dihydr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Ciblage de la voie de l'IGF (Insulin-like Growth Factor) en cancérologie pulmonaire

Keywords: Cancers bronchiques non à petites cellules; IGF-1; IGF-1R; CP 751,871; Non small cell lung cancer; IGF-1; IGF-1R; CP 751,871;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase

Keywords: IGF-1R; IGF-IR; Pyrrolopyridine; Kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity

Keywords: IGF-1R; IGF-IR; JNK; Pyrrolopyrimidine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Optimization of a series of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine inhibitors of IGF-1R: Elimination of an acid-mediated decomposition pathway

Keywords: IGF-1R; Pyrrolopyrimidine; IGF-IR; Kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase

Keywords: Pyrrolopyrimidine; IGF-1R; Kinase inhibitor; IGF-IR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Targeting of the protein interaction site between FAK and IGF-1R

Keywords: FAK; Protein–protein interaction; IGF-1R; Small molecule inhibitor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptor

Keywords: FAK; IGF-1R; Phosphorylation; Signaling; Degradation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibitors of insulin-like growth factor-1 receptor tyrosine kinase are preferentially cytotoxic to nutrient-deprived pancreatic cancer cells

Keywords: IGF-1R; IGF-1R kinase inhibitor; AG1024; Nutrient starvation; Pancreatic cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Safety, Pharmacokinetics, and Pharmacodynamics of the Insulin-Like Growth Factor Type 1 Receptor Inhibitor Figitumumab (CP-751,871) in Combination with Paclitaxel and Carboplatin

Keywords: IGF-1R; Figitumumab; CP-751,871; NSCLC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Saccharomyces boulardii Inhibits EGF Receptor Signaling and Intestinal Tumor Growth in Apcmin Mice

Keywords: EGFR; epidermal growth factor receptor; Erk; extracellular signal-regulated kinase; IGF-1R; insulin-like growth factor-1 receptor; MAP; mitogen-activated protein; PCNA; proliferating cell nuclear antigen; PKC; protein kinase C; Sb; Saccharomyces boulardii

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Aberrant intracellular IGF-1R β-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation

Keywords: IGF-1R; R-; Transformation; Oncogene; H-RasV12; Polyoma middle T-antigen;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Bone marrow cell-induced protection of the human myocardium: Characterization and mechanism of action

Keywords: 17; 29; 31; BMC; bone marrow cell; CK; creatine kinase; DAPI; 4′6-diamidino-2-phenylindole; ELISA; enzyme-linked immunosorbent assay; IGF; insulin-like growth factor; IGF-1R; insulin-like growth factor-1 receptor; IP; ischemic preconditioning; I/R; isch

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Sensitivity of breast cancer cell lines to the novel insulin-like growth factor-1 receptor (IGF-1R) inhibitor NVP-AEW541 is dependent on the level of IRS-1 expression

Keywords: Breast cancer; IGF-1R; IRS-1; Tyrosine kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Novel therapeutics in breast cancer—Looking to the future

Keywords: Breast cancer; HER-2; Trastuzumab-DM1; HSP-90; Epothilones; mTOR; IGF-1R; PKC inhibitors and PARP1 inhibitors

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

MVP expression is related to IGF1-R in cervical carcinoma patients treated by radiochemotherapy

Keywords: MVP; IGF-1R; Cervix carcinoma; Radiochemotherapy

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924

Keywords: IGF-1R; Tyrosine kinases; Anticancer agent; Benzimidazole; Haloimidazole; Halopyrazole

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

A Review of the Role of Insulin-like Growth Factor 2 in Malignancy and its Potential as a Modifier of Radiation Sensitivity

Keywords: Clonogenic survival; IGF2; IGF1; IGF-1R; irradiation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

PI3K/PTEN signaling in tumorigenesis and angiogenesis

Keywords: PI3K, phosphatidylinositol 3-kinase; RTK, receptor tyrosine kinase; mTOR, mammalian target of rapamycin; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; FGFR, fibroblast growth factor receptor; IGF, insulin-like growth factor; IGF-1R

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Tetraspanin CD81-Regulated Cell Motility Plays a Critical Role in Intrahepatic Metastasis of Hepatocellular Carcinoma

Keywords: cDNA; complementary DNA; CEV; CD81-enriched vesicle; FACS; fluorescence-activated cell sorting; GFP; green fluorescent protein; HCC; hepatocellular carcinoma; IGF-1R; insulin-like growth factor type 1 receptor; PCR; polymerase chain reaction; PI4KII; type

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors

Keywords: Imidazopyrazines; Insulin-like growth factor-I receptor; IGF-IR; IGF-1R; Tyrosine kinase inhibitor; Tumor growth inhibition; Cancer

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

IGF-1R expression in localized cervical carcinoma patients treated by radiochemotherapy

Keywords: IGF-1R; Cervix carcinoma; Definitive radiotherapy; Concomitant chemotherapy; Local control;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase

Keywords: Insulin-like growth factor; IGF-1R; Inhibitor; Kinase; ATP competitive; Benzimidazole; 4-Aminopyridone; Substituted 2-hydroxy-2-phenyl-aminoethanol

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs

Keywords: Nordihydroguaiaretic acid; NDGA; Insulin-like growth factor 1 receptor; IGF-1R; 15-Lipoxygenase; 15-LOX

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to improve cytochrome P450 profile

Keywords: Insulin-like growth factor-1 receptor; IGF-1R; Tyrosine kinase; Benzimidazole; Imidazole; CYP450 inhibition; Imidazoline; Pyridone

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Adenovirus expressing shRNA to IGF-1R enhances the chemosensitivity of lung cancer cell lines by blocking IGF-1 pathway

Keywords: Adenovirus; shRNA; siRNA; IGF-1R; Lung cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1

Keywords: Lycopene; MMP-9; NF-κB; Sp1; IGF-1R

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Novel roles of the IGF-IGFBP axis in etiopathophysiology of diabetic nephropathy

Keywords: ACEi; angiotensin-converting enzyme inhibitor; CTGF; connective tissue growth factor; DN; diabetic nephropathy; 4E-BP1; eukaryotic initiation factor 4E-binding protein; ecNOS; endothelial constitutive nitric oxide synthase; EGF; epidermal growth factor; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Functional responses and in vivo anti-tumour activity of h7C10: A humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors

Keywords: Monoclonal antibody; IGF-1R; Hybrid receptor; Ligand binding; Phosphorylation; Mouse xenograft model

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development

Keywords: p190-B; ARHGAP5; IGF-1R; IRS-1; IRS-2; Mammary bud; Epithelial–mesenchymal

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Retinal and choroidal microangiopathies: Therapeutic opportunities

Keywords: Angiogenesis; Vascularization; IGF-1; IGF-1R; VEGF; VEGFR-1; VEGFR-2; SDF-1; γ-secretase; Delta-like ligand 4; PEDF; IGFBP-3; Protein kinase CK2; Endothelial progenitor cell; Hematopoietic stem cell; Proliferative retinopathy; CD34; CD14; CD133; Hypoxia;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

IGF-1R tyrosine kinase expression and dependency in clones of IGF-1R knockout cells (R−)

Keywords: IGF-1 receptor; IGF-1R; R−; Knockout; PPP; Transformation; Microtubule

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Cross-talk between the calcium-sensing receptor and the epidermal growth factor receptor in Rat-1 fibroblasts

Keywords: Cao2+; extracellular calcium; OSE; ovarian surface epithelial; GPCR; G-protein-coupled receptor; CaR; calcium-sensing receptor; IP3; inositol triphosphate; Cai2+; intracellular calcium; ERK; extracellular signal regulated cascade; MAP kinase; mitogen-acti

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Steroid receptor coactivator-3, a homolog of Taiman that controls cell migration in the Drosophila ovary, regulates migration of human ovarian cancer cells

Keywords: Ab; antibody; EGF-R; epidermal growth factor receptor; ER; estrogen receptor; FAK; focal adhesion kinase; IGF-1R; insulin-like growth factor-1 receptor; siRNA; short interfering RNA; SRC-3; steroid receptor coactivator-3; Ovarian cancer; Cell migration; S

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

IGF-1 produced by cone photoreceptors regulates rod progenitor proliferation in the teleost retina

Keywords: Teleost; Fish; Retina; Insulin-like growth factor 1; IGF-1; IGF-1R; Neurogenesis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer

Keywords: AG1024; 3-bromo-5-t-butyl-4-hydroxy-benzylidenemalonitrile; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; erlotinib; (N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine); HCC; hepatocellular carcinoma; HMG-CoA-reductase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Expression of insulin-like growth factor system genes in liver and brain tissue during embryonic and post-hatch development of the turkey

Keywords: Development; Gene expression; Growth; Insulin-like growth factor system; IGF-I; IGF-II; IGF-1R; IGFBP; Turkey;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Aging Is Associated With Decreased Pancreatic Acinar Cell Regeneration and Phosphatidylinositol 3-Kinase/Akt Activation

Keywords: BrdU; 5-bromo-2'-deoxyuridine; IGF-1; insulin-like growth factor-1; IGF-1R; type 1 insulin-like growth factor receptor; MAPK; mitogen-activated protein kinase; pAkt; phosphorylated Akt; pERK; phosphorylated ERK; PI3K; phosphatidylinositol 3-kinase; pIGF

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

C. elegans DAF-12, Nuclear Hormone Receptors and human longevity and disease at old age

Keywords: AR; Androgen Receptor; BLAST; Basic Local Alignment Search Tool; CAR; Constitutive Androstane Receptor; CETP; Cholesterol Ester Transfer Protein; COUP-TF1/COUP-TF2; Chicken Ovalbumin Upstream Promoter Transcription Factor 1/2; CYP7A1; cholesterol-7-alpha-

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2005 سفارش ترجمه