Keywords: TSLP; thymic stromal lymphopoietin; TSLPR; TSLP receptor; iNKT; invariant natural killer T cell; TH; CD4+ T helper cell; ILC2; group 2 innate lymphoid cell; Ig; immunoglobulin; IFN; interferon; IL; interleukin; HMGB1; high-mobility group box 1 protein; PR
مقالات ISI (ترجمه نشده)
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Keywords: Alarmin; Bronchial asthma; IL-33; Innate immunity; Platelets; ADP; adenosine diphosphate; AERD; aspirin-exacerbated respiratory disease; cysLT; cysteinyl leukotriene; DAMPs; danger-associated molecular patterns; EETosis; eosinophil extracellular DNA trap
Keywords: Fungi; innate immunity; adaptive immunity; airway; ABPM; Allergic bronchopulmonary mycosis; AFRS; Allergic fungal rhinosinusitis; AHR; Airway hyperreactivity; CLR; C-type lectin receptor; CRS; Chronic rhinosinusitis; DC; Dendritic cell; DC-SIGN; Dendritic
Keywords: AA; Arachidonic acid; ALX/FPR2; Lipoxin A4/formyl peptide receptor 2; AnxA1; Annexin A1; ASA; Acetylsalicylic acid; AT; Aspirin-triggered; BHR; Bronchial hyper-reactivity; COX; Cyclooxygenase; DHA; Docosahexaenoic acid; Eos; Eosinophils; EPA; Eicosapentae
Keywords: Eosinophil; Eosinophil granule proteins; Eosinophil-related cutaneous disease; Eosinophil-related dermatoses; Eosinophilic cellulitis; Eosinophilic spongiosis; Skin disease; ALHE; Angiolymphoid hyperplasia with eosinophilia; CCL; C-C motif ligand; CCR3; C
Keywords: AhR; aryl hydrocarbon receptor; DMR; differentially methylated region; DNMT; DNA methyltransferases; HAT; histone acetyltransferase; HDAC; deacetylation occurs by histone deacetylase; HDM; house dust mite; ILC2; innate lymphoid cells; IM; interstitial mac
Keywords: Plasmacytoid dendritic cells; asthma; animal models of allergic airway disease; rhinovirus; asthma exacerbations; AAD; Allergic airway disease; BAL; Bronchoalveolar lavage; BDCA-2; Blood dendritic cell antigen 2; CRLF2; Cytokine receptor-like factor 2;
Keywords: Allergy; immunology; innate; inflammation; food allergy; asthma; mast cell; eosinophil; ozone; IL-33; extracellular vesicles; AERD; Aspirin-exacerbated respiratory disease; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; DP1;
Keywords: Aeroallergens; fungi; air pollutants; viral respiratory tract infections; climate change; occupational asthma; ABPA; Allergic bronchopulmonary aspergillosis; APIC; Asthma Phenotypes in the Inner City; BALF; Bronchoalveolar lavage fluid; BAT; Basophil acti
Keywords: hMab; humanized monoclonal antibody; ICS; inhaled corticosteroids; ILC2; innate type 2 lymphocytes; LABA; long-acting β2-agonist; Th2; T helper 2; TSLP; thymic stromal lymphopoietin;
Keywords: Group 2 innate lymphoid cells; aspirin-exacerbated respiratory disease; AERD; Aspirin-exacerbated respiratory disease; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; CysLT; Cysteinyl leukotriene; ILC2; Group 2 innate lymphoid
Keywords: Allergic rhinitis; Asthma; Spontaneous abortion; Preterm birth; Infant low birth weight; Allergy; CRS; Chronic rhinosinusitis; ILC2; Type 2 innate lymphoid cell; OR; Odds ratio; 1995 NSFG; 1995 National Survey of Family Growth; NHANES II or III; National
Keywords: Allergy; asthma; parasite infection; helminths; epidemiology; pathogenesis; AAMΦ; Alternatively activated macrophage; ES; Excretory-secretory; FOXP3; Forkhead box protein 3; GWAS; Genome-wide association study; ILC; Innate lymphoid cell; ILC2; Type 2 inn
Keywords: Virus; allergic inflammation; interferon; asthma; TH2; ACQ; Asthma Control Questionnaire; AE; Asthma exacerbation; AM; Alveolar macrophage; DC; Dendritic cell; GWAS; Genome-wide association study; HBEC; Primary bronchial epithelial cells; IFNAR; IFN-α re
Keywords: Immunotherapy; mechanisms; allergic rhinitis; allergic asthma; long-term tolerance; T cells; B cells; type 2 innate lymphoid cells; IgE-FAB; biomarkers; Breg; Regulatory B; C1Q; Component 1Q; CRTH2; Chemoattractant receptor-homologous molecule expressed
Keywords: Asthma; tight junction; innate immunity; cytokine; homeostasis; AhR; Aryl hydrocarbon receptor; AJ; Adherens junction; BHR; Bronchial hyperresponsiveness; CDHR3; Cadherin-related family member 3; DC; Dendritic cell; DUOX1; Dual oxidase 1; EGFR; Epidermal
Keywords: ILC2; iTr35; Tfh; Th1; Th2; Th22; CD; cluster of differentiation; CXCR5; CXC chemokine receptor 5; EBI3; Epstein-Barr virus-induced gene 3; FoxP3; forkhead box P3; IFN; interferon; ILC2; type 2 innate lymphoid cell; iTr35; IL-35-generated regulatory TÂ ce
Keywords: Type 2 inflammation; airway epithelium; mucociliary clearance; IL-13; IL-33; AAM; Alternatively activated macrophage; Actb; β-Actin gene; AHR; Airway hyperresponsiveness; ALI; Air-liquid interface; AM; Bronchoalveolar macrophage; APC; Allophycocyanin; BA
Keywords: aGVHD; acute GraftVSHost Disease; CR; Complete response; EGF; Epidermal growth factor; EGFR; The EGF receptor; FS; Follistatin; GI; Gastrointestinal; HCT; Hematopoietic Cell transplantation; IL; Interleukin; ILC2; Innante Lymphoid type 2 cells; ILCs; Inna
Keywords: Inflammation; macrophage; neutrophil; oxidative stress; cytokine; chemokine; autoantibody; nuclear factor κB; ASC; Apoptosis-associated speck-like protein containing a CARD; BAL; Bronchoalveolar lavage; COPD; Chronic obstructive pulmonary disease; EGFR;
Keywords: Atopic dermatitis; skin barrier; filaggrin; TH2; IL-4; IL-13; IL-31; IgE; innate; adaptive; skin; AD; Atopic dermatitis; AMP; Antimicrobial peptide; CNF; Cutaneous nerve fiber; DC; Dendritic cell; FLG; Filaggrin; HDM; House dust mite; ILC2; Type 2 innate
Keywords: Group 2 innate lymphoid cells; severe asthma; eosinophilic bronchitis; EoP; Eosinophilopoietic progenitor cell; HPC; Hematopoietic progenitor cell; ILC2; Group 2 innate lymphoid cell; IL-5R; IL-5 receptor; PE; Phycoerythrin; TSLP; Thymic stromal lymphopoi
Keywords: AA; arachidonic acid; AERD; aspirin exacerbated respiratory disease; BAL; bronchoalveolar lavage; CF; cystic fibrosis; CRSsNP; chronic rhinosinusitis without nasal polyps; CRSwNP; chronic rhinosinusitis with nasal polyps; ILC2; type 2 innate lymphocytes;
Keywords: asthma; COPD; pulmonary fibrosis; pulmonary hypertension; ADDS; antibody-dependent degranulatory synapse; ASM; airway smooth muscle; β2-AR; β2-adrenergic receptor; Ca2+; calcium ion; CADM1; cell adhesion molecule 1; CD; cluster of differentiation; CPA3;
Keywords: Innate lymphoid cells; mucosal immunity; inflammatory bowel disease; allergy; asthma; psoriasis; tumor immunity; graft-versus-host disease; AD; Atopic dermatitis; ART; Antiretroviral therapy; γc; Common γ chain; CLP; Common lymphoid progenitor; cNK; Con
Keywords: Asthma; Eosinophilic inflammation; Biomarker; ILC2; ILC2; type 2 innate lymphoid cell; %ILC2; the proportion of ILC2s of peripheral blood lymphocytes; IgE; total immunoglobulin E; FeNO; fractional exhaled nitric oxide; BMI; body mass index; ROC; receiver
Keywords: Childhood asthma phenotypes; immune-regulatory mechanisms; innate immunity; linear discriminant analysis; peripheral blood mononuclear cells; regulatory T cells; transcriptomics; AA; Allergic asthma; ATS; American Thoracic Society; CLIC4; Chloride intrace
Keywords: Corticosteroids; bronchodilator; cytokine; chemokine; IgE; kinase; p38 mitogen-activated protein kinase; bronchial thermoplasty; corticosteroid resistance; macrolide; ACOS; Asthma-chronic obstructive pulmonary disease overlap syndrome; COPD; Chronic obs
Keywords: NK cells; ILC2; ILC3; ILC development; NCR
Keywords: Asthma; epithelium; dendritic cells; TH2; AAM; Alternatively activated macrophage; BEC; Bronchial epithelial cell; cDC; Conventional dendritic cell; DC; Dendritic cell; FCP; Fibrinogen cleavage product; HDM; House dust mite; HM-GB1; High-mobility group bo
Keywords: IL-33; IL-25; IL-5; IL-13; ILC2; innate immunity; asthma; allergy; AA; Allergic asthma; AR; Allergic rhinitis; FITC; Fluorescein isothiocyanate; ILC2s; Group 2 innate lymphoid cells; HC; Healthy control; Linâ; Lineage-negative; Lin+; Lineage-positive; S
Keywords: APC; antigen presenting cell; BAL; bronchoalveolar lavage; CBM; chromatin-binding motiff; CAV; chronic allograft vasculopathy; DC; dendritic cells; DC-SIGN; DC-specific intercellular adhesion molecule-3-grabbing non-integrin; DSA; donor specific antibodie
Elimination of eosinophils using anti-IL-5 receptor alpha antibodies effectively suppresses IL-33-mediated pulmonary arterial hypertrophy
Keywords: ADCC; antibody dependent cell-mediated cytotoxicity; IL; IL-5; IL-5Rα; IL-5 receptor α chain; ILC2; group 2 innate lymphoid cell; Th2; T helper type 2; PAH; pulmonary arterial hypertension; CDR; complementary determining region; SMA; smooth muscle actin
Cyclosporin A indirectly attenuates activation of group 2 innate lymphoid cells in papain-induced lung inflammation
Keywords: BAL; bronchoalveolar lavage; CsA; cyclosporin A; ICOS; inducible T cell costimulator; ICOSL; inducible T cell costimulator ligand; ILC2s; group 2 innate lymphoid cells; NFAT; nuclear factor of activated T-cells; Th2; type 2 helper T; TSLP; thymic stromal
Dichotomous function of IL-33 in health and disease: From biology to clinical implications
Keywords: AREG; amphiregulin; Breg; regulatory B cells; CML-1; CMRF35-like molecule-1; CNS; central nervous system; COPD; chronic obstructive pulmonary disease; DAMP; damage-associated molecular pattern; DC; dendritic cells; DUOX1; dual oxidase 1; EAE; experimental
Antiapoptotic serine protease inhibitors contribute to survival of allergenic TH2 cells
Keywords: TH2 cells; apoptosis; memory; grass pollen allergy; AICD; Activation-induced cell death; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; CRTH2; Prostaglandin D2 receptor; FACS; Fluorescence-activated cell sorting; ICS; Intracellular staining; ILC1; Inn
The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D
Keywords: Allergy; asthma; Staphylococcus aureus; sensitization; serine protease; AECII; Airway epithelial cell type II; APC; Allophycocyanin; BALF; Bronchoalveolar lavage fluid; DC; Dendritic cells; DMEM; Dulbecco modified Eagle medium; FACS; Fluorescence-activate
Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations
Keywords: Asthma; type 2 innate lymphoid cells; IL-33 receptor; thymic stromal lymphopoietin; IL-9; mast cells; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; FITC; Fluorescein isothiocyanate; FoxP3; Forkhead box P3; ICOS; Inducible costimulator; ILC; Innate ly
Monocyte chemotactic protein-induced protein 1 controls allergic airway inflammation by suppressing IL-5-producing TH2 cells through the Notch/Gata3 pathway
Keywords: RNA-Binding protein; MCPIP1; mRNA decay; TH2 cells; IL-4; IL-5; IL-13; Gata3; Notch; asthma; BALF; Bronchoalveolar lavage fluid; CARMA1; Caspase recruitment domain-containing MAGUK protein 1; DLL; Delta-like; GSI; Gamma secretase inhibitor; HDM; House dus
Vitamin D in Asthma
Keywords: airway immunology; asthma; T-helper cells; vitamin D; 25(OH)D; 25-hydroxyvitamin D; DC; dendritic cell; IL; interleukin; ILC2; type 2 innate lymphoid cell; Treg; regulatory T lymphocytes;
MicroRNAs in type 2 immunity
Keywords: MicroRNA; IL-13; IL-4; IL-5; TH2; ILC2; Allergy; Parasite; Cancer;
Activated plasmacytoid dendritic cells regulate type 2 innate lymphoid cell-mediated airway hyperreactivity
Keywords: Type 2 innate lymphoid cells; asthma; plasmacytoid dendritic cells; eosinophilic airway inflammation; immune regulation; AHR; Airway hyperreactivity; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; DT; Diphtheria toxin; DTR; Diphtheria toxin receptor;
Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity
Keywords: IL-33; rhinovirus; asthma; exacerbation; antiviral; AEC; Airway epithelial cell; ASM; Airway smooth muscle; BALF; Bronchoalveolar lavage fluid; CRE; Cockroach extract; FITC; Fluorescein isothiocyanate; HMGB1; High-mobility group box 1; ILC2; Type 2 innate
Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses
Keywords: Neonatal hyperoxia; oxidative stress; asthma; IL-33; ILC2s; AHR; Airway hyperresponsiveness; BPD; Bronchopulmonary dysplasia; DC; Dendritic cell; HDM; House dust mite; ILC2; Group 2 innate lymphoid cell; PAS; Periodic acid-Schiff; PN; Postnatal; RA; Roo
Prostaglandin E2 suppresses human group 2 innate lymphoid cell function
Keywords: ILC2; allergy; prostaglandin E2; E-type prostanoid receptor 2; E-type prostanoid receptor 4; cAMP; Cyclic AMP; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; EP; E-type prostanoid receptor; ILC; Innate lymphoid cell; ILC2; Gro
Cytokines as therapeutic targets in primary Sjögren syndrome
Keywords: APC; antigen-presenting cells; APRIL; a proliferation-inducing ligand; Auto-Ab; autoantibodies; BAFF; B-cell activating factor; BCR; B-cell receptor; Bm; mature B cell; BR3; B-cell activating factor receptor 3; DC; dendritic cell; FDC; follicular dendriti
TH1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status
Keywords: Severe asthma; allergic; IgE; IFN-γ; IL-4; IL-5; IL-23; IL-33; IL-28A; TH1 cells; TH2 cells; TH17 cells; type 2 innate lymphoid cells; BAL; Bronchoalveolar lavage; GM; Geometric mean; ILC2; Type 2 innate lymphoid cell; Lin; Lineage; mDC; Myeloid dendrit
New Anti-Eosinophil Drugs for Asthma and COPD
Keywords: airway inflammation; asthma; COPD; eosinophils; pharmacotherapy; CRTH2; chemoattractant receptor-homologous molecules expressed on Th2 cells; FeNO; fraction of exhaled nitric oxide; ILC2; type 2 innate lymphoid cells; Rα; receptor alpha; Th2; T helper 2;
Increased frequencies of basophils, type 2 innate lymphoid cells and Th2 cells in skin of patients with atopic dermatitis but not psoriasis
Keywords: AD; atopic dermatitis; Pso; psoriasis; Th2 cells; type 2 CD4+ helper T cells; ILCs; innate lymphoid cells; ILC2; group 2 ILCs; ILC3; group 3 ILCs; mAb; monoclonal antibody; PBMC; peripheral blood mononuclear cells; PMA; phorbol myristate acetate; Basophil
IL-9 and Th9 cells in health and diseases-From tolerance to immunopathology
Keywords: TNFRSF; Tumor necrosis factor receptor super family; GITR; Glucocorticoid-induced tumor necrosis factor receptor; DR3; Death receptor 3; ILC2; Type II innate lymph cells; CNS; Conserved non-coding sequences; TSS; Transcription start site; TCR; T cell rece