Second generation S1P pathway modulators: Research strategies and clinical developments
Keywords: ایمونومولاتور; Immunomodulator; S1P modulator; S1P1; Fingolimod
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Discovery of oxazole and triazole derivatives as potent and selective S1P1 agonists through pharmacophore-guided design
Keywords: ایمونومولاتور; S1P1 agonist; Immunomodulator; Prodrug; Pharmacophore; Lymphocyte
Anti-Tumor Necrosis Factor-α Monotherapy Versus Combination Therapy with an Immunomodulator in IBD
Keywords: ایمونومولاتور; Anti-TNF; Immunomodulator; Monotherapy; Combination therapy;
Immunomodulatory effects of silymarin in patients with β-thalassemia major
Keywords: ایمونومولاتور; Thalassemia; Cytokine; Silymarin; Immunomodulator; Cell-mediated immunity; Lymphocyte;
Antitumor and immunomodulatory effects of salvigenin on tumor bearing mice
Keywords: ایمونومولاتور; Salvigenin; Immunomodulator; Regulatory T cells; IFN-γ; IL-4
Modulation of inflammatory bowel disease in a mouse model following infection with Trichinella spiralis
Keywords: ایمونومولاتور; Trichinella spiralis; Inflammatory bowel disease; Colonic immunity; Immunomodulator
Synthesis of conformationally constrained γ-d-glutamyl-meso-diaminopimelic acid derivatives as ligands of nucleotide-binding oligomerization domain protein 1 (Nod1)
Keywords: ایمونومولاتور; Nod1; Immunomodulator; γ-d-Glutamyl-meso-diaminopimelic acid; NF-κB activation; Immunotoxicity; ImmunostimulantC12-iE-DAP, lauroyl-γ-d-glutamyl-meso-diaminopimelic; DBU, 1,8-diazabicyclo[5.4.0]undec-7-ene; iE-DAP, γ-d-glutamyl-meso-diaminopimelic acid; IL
Structure-activity relationship studies of S1P agonists with a dihydronaphthalene scaffold
Keywords: ایمونومولاتور; S1P agonist; Immunomodulator; Dihydronaphthalene;
Immunomodulatory properties of Beta-sitosterol in pig immune responses
Keywords: ایمونومولاتور; Phytosterols; Immunomodulator; PRRSV; Swine
Les avancées de l'immunothérapie dans les cancers bronchiques non à petites cellules
Keywords: ایمونومولاتور; Cancer bronchique; Immunothérapie; Immunomodulateur; Anticorps monoclonal; Vaccin; Lung cancer; Immunotherapy; Immunomodulator; Monoclonal antibody; Vaccine;
New conjugates of muramyl dipeptide and nor-muramyl dipeptide linked to tuftsin and retro-tuftsin derivatives significantly influence their biological activity
Keywords: ایمونومولاتور; muramyl dipeptide; nor-muramyl dipeptide; tuftsin derivatives; synthesis; immunomodulator
Macrophage immunomodulatory activity of extracellular polysaccharide (PEP) of Antarctic bacterium Pseudoaltermonas sp.S-5
Keywords: ایمونومولاتور; Antarctic bacteria; Pseudoaltermonas sp.S-5; Polysaccharide; Immunomodulator; Macrophages;
Recent research and developmental strategy of anti-asthma drugs
Keywords: ایمونومولاتور; Asthma; Allergic inflammation; Glucocorticoid; Controller; Reliever; Immunomodulator; Lipid mediator
G1-4 A, an arabinogalactan polysaccharide from Tinospora cordifolia increases dendritic cell immunogenicity in a murine lymphoma model
Keywords: ایمونومولاتور; iBMDC; immature bone marrow derived dendritic cells; mBMDC; mature bone marrow derived dendritic cells; LP; lysate pulsed; PP; peptide pulsed; Tinospora cordifolia; Dendritic cells; Immunomodulator; Adjuvant; Immunotherapy;
CsCXCe1: A novel Cynoglossus semilaevis CXC chemokine that functions as a chemoattractant and an immunomodulator for peripheral blood leukocytes
Keywords: ایمونومولاتور; CXC chemokine; Cynoglossus semilaevis; Chemotaxis; Immunoregulation; Immunomodulator;
Very small size proteoliposomes derived from Neisseria meningitidis: An effective adjuvant for antigen-specific cytotoxic T lymphocyte response stimulation under leukopenic conditions
Keywords: ایمونومولاتور; VSSP; Adjuvant; Immunosuppression; Immunomodulator; Leukopenia;
Adalimumab for the induction and maintenance of clinical remission in Japanese patients with Crohn's disease
Keywords: ایمونومولاتور; CD; Crohn's disease; PPD; purified protein derivative; TPN; total parenteral nutrition; CDAI; CD activity index; CR-70; decrease in CDAI score from Baseline â¥Â 70; CR-100; decrease in CDAI score from Baseline â¥Â 100; eow; every other week; 6-MP; 6-m
Structure–activity relationship studies of sphingosine-1-phosphate receptor agonists with N-cinnamyl-β-alanine moiety
Keywords: ایمونومولاتور; LPVUWRPVJHEUFU-QGOAFFKASA-N; MDNBHQVSBWFJLJ-UHFFFAOYSA-NS1P agonist; Immunomodulator
Discovery of S1P agonists with a dihydronaphthalene scaffold
Keywords: ایمونومولاتور; S1P agonist; Immunomodulator; Dihydronaphthalene
Interleukin-6 expression in response to innate immune regulatory factor stimulation
Keywords: ایمونومولاتور; Interleukin-6; Immunomodulator; Acute phase protein; Biological response modifier
Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator-Picroliv
Keywords: ایمونومولاتور; Therapeutic switching; Ketoconazole; Miltefosine; Picroliv; Immunomodulator; Leishmania donovani;
Effect of polysaccharide from cultured Cordyceps sinensis on immune function and anti-oxidation activity of mice exposed to 60Co
Keywords: ایمونومولاتور; Cordyceps sinensis; Immunomodulator; Anti-oxidation;
A phytoceramide analog stimulates the production of chemokines through CREB activation in human endothelial cells
Keywords: ایمونومولاتور; CREB; Drosophila; Immunomodulator; Innate immunity; NF-κB; Phytoceramide;
Oral laquinimod treatment in multiple sclerosis
Keywords: ایمونومولاتور; Multiple sclerosis; Immunomodulator; Laquinimod; Oral TreatmentsEsclerosis múltiple; Inmunomodulador; Laquinimod; Tratamientos orales
Antitumor and immunomodulatory properties of artemether and its ability to reduce CD4+ CD25+ FoxP3+ T reg cells in vivo
Keywords: ایمونومولاتور; Breast cancer; Antitumor; Immunomodulator; Regulatory T cells;
Effect of Alnus japonica extract on a model of atopic dermatitis in NC/Nga mice
Keywords: ایمونومولاتور; Alnus japonica; Immunomodulator; Th2; Atopic dermatitis
Evaluation of imiquimod for topical treatment of vaccinia virus cutaneous infections in immunosuppressed hairless mice
Keywords: ایمونومولاتور; Poxvirus; Imiquimod; Immunomodulator; Cidofovir; Antiviral; Cyclophosphamide
Design, synthesis and biological evaluation of novel desmuramyldipeptide analogs
Keywords: ایمونومولاتور; MDP; Immunomodulator; Desmuramyldipeptide; Immunotoxicity; Immunostimulant; Anti-inflammatory agentDAG, diacylglycerol; GMDP, glucosaminyl muramyl dipeptide; H4R, H4 receptor; IL, interleukin; LDH, lactate dehydrogenase; LPS, lipopolysaccharide; LTA, lipo
Future Forms of Immunotherapy and Immunomodulators in Allergic Disease
Keywords: ایمونومولاتور; Immunotherapy; Immunomodulator; Cytokine; Allergic rhinitis; Asthma;
Tehranolide molecule modulates the immune response, reduce regulatory T cell and inhibits tumor growth in vivo
Keywords: ایمونومولاتور; DTH, delayed type hypersensitivity, SMMTspontaneous mouse mammry tumor, FBSfetal bovine serum, sRBCsheep red blood cells, MNCsmononuclear cellsTehranolide; T regulatory cell; IFN-γ; IL-4; Immunomodulator
Effect of imiquimod on partial-thickness burns
Keywords: ایمونومولاتور; Imiquimod; Immunomodulator; Inflammation; Collagen; Burns; Rats
Safety Profile of IBD Therapeutics: Infectious Risks
Keywords: ایمونومولاتور; Inflammatory bowel disease; Infection; Corticosteroids; Immunomodulator; Anti-tumor necrosis factor;
The influence of traditional herbal formulas on cytokine activity
Keywords: ایمونومولاتور; Cytokine; Herbal formula; Immunomodulator; Traditional medicine; Interleukin (IL); Tumor necrosis factor (TNF)
A biotechnological product and its potential as a new immunomodulator for treatment of animal phlebovirus infection: Punta Toro virus
Keywords: ایمونومولاتور; Immunomodulator; Virus; Punta Toro virus; P-MAPA
First chemoenzymatic synthesis of immunomodulating macrolactam pimecrolimus
Keywords: ایمونومولاتور; Lipase; Immunomodulator; Macrolactam; Ascomycin; Regioselectivity;
Derivatives of human β-Casein fragments (54–59) exhibit highly potent immunosuppressant activity
Keywords: ایمونومولاتور; Human β-casein fragments; Immunosuppressant peptide; Immunomodulator; Lymphocytes proliferation
Glatiramer acetate positively influences spinal motoneuron survival and synaptic plasticity after ventral root avulsion
Keywords: ایمونومولاتور; Ventral root avulsion; Spinal cord; Synapse elimination; Motoneuron; Immunomodulator; Glatiramer acetate
c-di-GMP as a vaccine adjuvant enhances protection against systemic methicillin-resistant Staphylococcus aureus (MRSA) infection
Keywords: ایمونومولاتور; Staphylococcus aureus; c-di-GMP; MRSA; Adjuvant; Vaccine; Immunomodulator;
Enhanced endogenous type I interferon cell-driven survival and inhibition of spontaneous apoptosis by Riluzole
Keywords: ایمونومولاتور; Human; AIDS; Interferon; HIV; Cytokines; Immunomodulator; Apoptosis; Cell survival; Riluzole
Recombinant Mycobacterium bovis BCG
Keywords: ایمونومولاتور; Mycobacterium bovis BCG; Recombinant BCG; Heterologous expression; Immunomodulator
Safety Profile of IBD Therapeutics: Infectious Risks
Keywords: ایمونومولاتور; Inflammatory bowel disease; Infection; Corticosteroids; Immunomodulator; Anti-tumor necrosis factor;
The addition of a new immunomodulator with the adjuvant adaptation ADAD system using fatty acid binding proteins increases the protection against Fasciola hepatica
Keywords: ایمونومولاتور; Fasciola hepatica; FABP; Immunomodulator; Vaccine; Lipidic aminoalcohol; OA0012
Effect of oral immunomodulator Dzherelo in TB/HIV co-infected patients receiving anti-tuberculosis therapy under DOTS
Keywords: ایمونومولاتور; Mycobacterium tuberculosis; HIV; Herbal; Phytotherapy; Immunotherapy; Immunomodulator
Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720
Keywords: ایمونومولاتور; S1P, sphingosine 1-phosphate; FTY720-P, FTY720 phosphate; HDL, high-density lipoprotein; ABC, ATP-binding cassetteSphingosine 1-phosphate; FTY720; Erythrocyte; Platelet; Immunomodulator; Sphingolipid
Macrophage immunomodulatory activity of polysaccharides isolated from Glycyrrhiza uralensis fish
Keywords: ایمونومولاتور; Glycyrrhiza uralensis Fish; Polysaccharides; Immunomodulator; Macrophage; Cytokine
Immunomodulating and antiviral activities of Uncaria tomentosa on human monocytes infected with Dengue Virus-2
Keywords: ایمونومولاتور; Uncaria tomentosa; Dengue; Cytokines; Immunomodulator; Alkaloids; Antiviral
c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection
Keywords: ایمونومولاتور; Streptococcus pneumoniae; c-di-GMP; Immunomodulator; Adjuvant; Vaccine
Contribution of dectin-1 and granulocyte macrophage–colony stimulating factor (GM-CSF) to immunomodulating actions of β-glucan
Keywords: ایمونومولاتور; β-Glucans; Granulocyte macrophage–colony stimulating factor (GM-CSF); Immunomodulator
The beneficial effect of Rheum tanguticum polysaccharide on protecting against diarrhea, colonic inflammation and ulceration in rats with TNBS-induced colitis: The role of macrophage mannose receptor in inflammation and immune response
Keywords: ایمونومولاتور; Rheum tanguticum polysaccharide; Immunomodulator; Macrophage mannose receptor; Cytokine; Endocytosis; Colitis
Fractionation and characterization of biologically-active polysaccharides from Artemisia tripartita
Keywords: ایمونومولاتور; Artemisia tripartita Rydb; Asteraceae; Immunomodulator; Polysaccharide; Macrophage; Neutrophil; Complement-fixing activity; Reactive oxygen species; Cytokines;