Keywords: کوتیزولاتور قابل انعطاف; Ectopic lymphoid tissue; immunoglobulin; lymphoid aggregate; lymphorganogenesis; AID; Activation-induced cytidine deaminase; BAFF; B cell-activating factor of the TNF family; Bcl; B-cell lymphoma; CD21L; CD21 ligand; CRSsNP; Chronic rhinosinusitis witho
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A novel mouse model for tracking the fate of CXCR5-expressing T cells
Keywords: کوتیزولاتور قابل انعطاف; Follicular helper T cells; CXCR5; Memory T cells; Humoral immunity; GC; Germinal center; Tfh; Follicular helper T; OVA; Ovalbumin; CXC-R5; C-X-C chemokine receptor type 5; CCR7; C-C chemokine receptor type 7; ICOS; Inducible costimulator; PD-1; Programmed
Pathogenic and protective roles of B cells and antibodies in patients with chronic rhinosinusitis
Keywords: کوتیزولاتور قابل انعطاف; Antibodies; antibody deficiency; autoimmunity; chronic rhinosinusitis; B cells; immunodeficiency; mucosal immunity; BAFF; B-cell activating factor of the TNF family; BAFF-R; B-cell activating factor of the TNF family receptor; CRS; Chronic rhinosinusitis;
Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations
Keywords: کوتیزولاتور قابل انعطاف; Asthma; type 2 innate lymphoid cells; IL-33 receptor; thymic stromal lymphopoietin; IL-9; mast cells; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; FITC; Fluorescein isothiocyanate; FoxP3; Forkhead box P3; ICOS; Inducible costimulator; ILC; Innate ly
Dendritic cells conditioned by activin A-induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma
Keywords: کوتیزولاتور قابل انعطاف; Activin-A; allergic asthma; regulatory T cells; tolerogenic dendritic cells; immune regulation; Act-A-Treg; Activin-A-induced regulatory T; alum; Aluminum hydroxide; BAL; Bronchoalveolar lavage; BM-DCs; Bone marrow-derived dendritic cell; cDC; Convent
Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice
Keywords: کوتیزولاتور قابل انعطاف; Costimulation; Inflammation; Intestine; Proinflammatory cytokine; Roquin; ICOS; inducible costimulator; IELs; intraepithelial lymphocytes; KLRG1; killer cell lectin-like receptor subfamily G member 1; LPLs; lamina propria lymphocytes; LCA; leukocyte commo
Depletion of regulatory T cells by anti-ICOS antibody enhances anti-tumor immunity of tumor cell vaccine in prostate cancer
Keywords: کوتیزولاتور قابل انعطاف; PC; prostate cancer; DC; dendritic cell; FITC; fluorescein isothiocyanate; mGM-CSF; mouse granulocyte macrophage colony-stimulating factor; PBS; PHOSPHATE buffered saline; SA; streptavidin; Tregs; regulatory T cells; ICOS; inducible costimulator; Foxp3; f
Modification of cytokine-induced killer cells with folate receptor alpha (FRα)-specific chimeric antigen receptors enhances their antitumor immunity toward FRα-positive ovarian cancers
Keywords: کوتیزولاتور قابل انعطاف; ACT; adoptive cellular immunotherapy; AICD; activation induced cell death; ALL; acute lymphocytic leukemia; AML; acute myeloid leukemia; BsAb; bispecific antibody; CA125; cancer antigen-125; CARs; chimeric antigen receptors; CBMCs; cord blood mononuclear
Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation
Keywords: کوتیزولاتور قابل انعطاف; STAT1 gain of function; IFN-γ; ruxolitinib; autoimmunity; TH1 cell; TH17 cell; follicular T helper cell; T helper cell polarization; ATG; Anti-thymocyte globulin; BSA; Body surface area; GOF; Gain of function; IC50; Half-maximal inhibitory concentration
Human regulatory B cells control the TFH cell response
Keywords: کوتیزولاتور قابل انعطاف; Regulatory B cells; follicular T helper cells; IL-12; IL-21; antibody production; humoral immune response; Bcl-6; B-cell lymphoma 6; Breg; Regulatory B; DC; Dendritic cell; Foxp3; Forkhead box P3; GC; Germinal center; ICAM; Intercellular adhesion molecule
Follicular helper T cells mediate IgE antibody response to airborne allergens
Keywords: کوتیزولاتور قابل انعطاف; Follicular T cells; IL-4; IgE; allergy; allergens; TH2 cells; APC; Antigen-presenting cell; BAL; Bronchoalveolar lavage; eGFP; Enhanced green fluorescent protein; FACS; Fluorescence-activated cell sorting; GC; Germinal center; HDM; House dust mite; ICOS;
Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice
Keywords: کوتیزولاتور قابل انعطاف; Allergic mechanisms; innate lymphoid cells; mouse models; CLP; Common lymphoid progenitor; DAPI; 4â²,6-Diamidino-2-phenylindole; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; ILC2; Type 2 innate lymphoid cell; IL-7Rα; IL-7 receptor α; iNKT;
Nasal IL-4+CXCR5+CD4+ T follicular helper cell counts correlate with local IgE production in eosinophilic nasal polyps
Keywords: کوتیزولاتور قابل انعطاف; B cell; ectopic lymphoid structure; eosinophil; IgE; IL-4; nasal polyp; T follicular helper cell; Bcl-6; Transcription factor B-cell lymphoma 6; Bm; B mature; CRSwNP; Chronic rhinosinusitis with nasal polyps; CSR; Class-switch recombination; FACS; Fluores
IL-25 and CD4+ TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy
Keywords: کوتیزولاتور قابل انعطاف; IL-25; type 2 innate lymphoid cells; CD4+ TH2 cells; IL-13; food allergy; APC; Allophycocyanin; BM; Bone marrow; CT; Cholera toxin; FITC; Fluorescein isothiocyanate; 4GET; Il4 expression-driven GFP reporter; GFP; Green fluorescent protein; ICOS; Inducib
Role of IL-4 receptor α-positive CD4+ T cells in chronic airway hyperresponsiveness
Keywords: کوتیزولاتور قابل انعطاف; TH2 cell; acute allergic airway disease; chronic asthma; cytokine receptors; IL-4; IL-13; gene-deficient mice; AHR; Airway hyperresponsiveness; BAL; Bronchoalveolar lavage; FITC; Fluorescein isothiocyanate; ICOS; Inducible costimulator; ILC2; Type 2 innat
A signaling-enhanced chimeric receptor to activate the ICOS pathway in T cells
Keywords: کوتیزولاتور قابل انعطاف; ADA; anti-drug antibody; CD3; cluster of differentiation 3; B7RP1; B7 related protein 1; ICOS; inducible costimulator; TCR; T cell receptor; ICOS-CD3; chimeric receptor consisting of full-length ICOS and the cytoplasmic region of CD3 zeta; ITAM; immune
ICOS promotes group 2 innate lymphoid cell activation in lungs
Keywords: کوتیزولاتور قابل انعطاف; Group 2 innate lymphoid cell; Inducible costimulator; Allergic lung inflammation;
Mechanisms of allergy and clinical immunologyHuman B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures
Keywords: کوتیزولاتور قابل انعطاف; B cell; T-cell plasticity; IL-21; IFN-γ; coexpression; T-bet; Bcl-6; antibody response; crosstalk; Bcl-6; B cell lymphoma 6; DC; Dendritic cell; DP; Double positive; ICOS; Inducible costimulator; LN; Lymph node; PD-1; Programmed cell death 1; PE; Phycoer
Atopic dermatitis and skin diseaseEarly pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)+ TH2/TH1 cell imbalance, whereas adults acquire CLA+ TH22/TC22 cell subsets
Keywords: کوتیزولاتور قابل انعطاف; Atopic dermatitis; T cell; cutaneous lymphocyte antigen; IL-13; IL-22; IFN-γ; inducible costimulator; CD69; HLA-DR; AD; Atopic dermatitis; CLA; Cutaneous lymphocyte antigen; ICOS; Inducible costimulator; PE; Phycoerythrin; PMA; Phorbol 12-myristate 13-ac
Asthma and lower airway diseasePediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33
Keywords: کوتیزولاتور قابل انعطاف; Severe asthma; fungal sensitization; pediatric; IL-33; innate immunity; steroid resistance; ABPA; Allergic bronchopulmonary aspergillosis; AHR; Airway hyperresponsiveness; BAL; Bronchoalveolar lavage; HDM; House dust mite; ICOS; Inducible costimulator; IL
IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice
Keywords: کوتیزولاتور قابل انعطاف; IL-33; lung fibrosis; alternatively activated macrophages; type 2 innate lymphoid cells; APC; Allophycocyanin; Arg1; Arginase 1; BAL; Bronchoalveolar lavage; BMDM; Bone marrow-derived macrophage; CT; Computed tomography; FITC; Fluorescein isothiocyanate
Differential induction of IL-17, IL-10, and IL-9 in human T helper cells by B7h and B7.1
Keywords: کوتیزولاتور قابل انعطاف; TH; T helper; APC; antigen-presenting cells; TCR; T cell receptor; mAbs; monoclonal antibody; PBMC; peripheral blood mononuclear cells; ICOS; inducible costimulator; TGF-β; transforming growth factor-β; IL-; interleukine-; INF-γ; interferon-γ; PB; per
Regulatory T cells in atherosclerosis and strategies to induce the endogenous atheroprotective immune response
Keywords: کوتیزولاتور قابل انعطاف; LDL; low density lipoprotein; Tregs; regulatory T cells; IL; interleukin; TGF-β; transforming growth factor beta; Foxp3; forkhead box 3; IL-2R; interleukin-2 receptor; CTLA-4; cytotoxic T-lymphocyte antigen 4; NK; natural killer; DCs; dendritic cells; TC
Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency
Keywords: کوتیزولاتور قابل انعطاف; Human; T cells; signal transducer and activator of transcription 3 deficiency; cell activation; naive B cells; Bcl6; B-cell lymphoma 6; CD40L; CD40 ligand; CD62L; L-selectin; CSR; Class-switch recombination; GC; Germinal center; ICOS; Inducible costimulat
Expansion of circulating counterparts of follicular helper T cells in patients with myasthenia gravis
Keywords: کوتیزولاتور قابل انعطاف; Myasthenia gravis; Follicular helper T cells; Inducible costimulator; CXC-chemokine ligand 13; Anti-acetylcholine receptor antibody
Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity
Keywords: کوتیزولاتور قابل انعطاف; Nuocytes; IL-13; asthma; IL-25; IL-33; AHR; Airways hyperreactivity; BAL; Bronchoalveolar lavage; ICOS; Inducible costimulator; IL-4eGFP; IL-4-enhanced green fluorescent protein; IL-13Tom; IL-13 tomato fluorescent protein; OVA; Ovalbumin; PE; Phycoeryth
IL-33 induces innate lymphoid cell-mediated airway inflammation by activating mammalian target of rapamycin
Keywords: کوتیزولاتور قابل انعطاف; IL-33; TH2; innate lymphoid cells; asthma; mammalian target of rapamycin; rapamycin; AHR; Airway hyperresponsiveness; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; Lin; Lineage-specific marker;
Dysregulated Generation of Follicular Helper T Cells in the Spleen Triggers Fatal Autoimmune Hepatitis in Mice
Keywords: کوتیزولاتور قابل انعطاف; Autoimmune Liver Disease; Pathogenesis; Follicular Helper T Cells; AIH; autoimmune hepatitis; ANA; antinuclear antibody; APC; allo-phycocyanin; CXCR; CXC chemokine receptor; EAE; experimental autoimmune encephalomyelitis; GC; germinal center; ICOS; induci
Asthma translational medicine: Report card
Keywords: کوتیزولاتور قابل انعطاف; ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AP-1; activator protein 1; APC; antigen-presenting cell; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; CTLA-4; cytotoxic T lymphocyte-associated antigen
Reviews and feature articleTH2 heterogeneity: Does function follow form?
Keywords: کوتیزولاتور قابل انعطاف; TH2; heterogeneity; T cell; IL-5; differentiation; lineage; DC; Dendritic cell; ICCS; Intracellular cytokine staining; ICOS; Inducible costimulator; PD-1; Programmed death 1; TFH; Follicular helper; TSLP; Thymic stromal lymphopoietin;
Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells
Keywords: کوتیزولاتور قابل انعطاف; Regulatory T cells; ICOS; antigen-specificity; TH17/TH1 features; skin inflammation; allergic contact dermatitis; haptens; CHS; Contact hypersensitivity; DC; Dendritic cell; dLN; Draining lymph node; DNBS; 2,4-Dinitrobenzene-sulfonic acid; DNFB; 2,4-Dinit
Blockade of inducible costimulator pathway to prevent acute rejection in rat liver transplantation
Keywords: کوتیزولاتور قابل انعطاف; Acute rejection; Inducible costimulator; Live transplantation; RNA interference; T lymphocyte
Defects of mitogen-activated protein kinase in ICOS signaling pathway lead to CD4+ and CD8+ T-cell dysfunction in patients with active SLE
Keywords: کوتیزولاتور قابل انعطاف; Systemic lupus erythematosus; MAP kinase; IL-2; Inducible costimulator
Regulatory dendritic cells protect against allergic airway inflammation in a murine asthmatic model
Keywords: کوتیزولاتور قابل انعطاف; Dendritic cells; TH2 cells; T regulatory cells; tolerance; IgE; airway hyperreactivity; APC; Antigen-presenting cell; BALF; Bronchoalveolar lavage fluid; DC; Dendritic cell; DCreg; Regulatory dendritic cell; DNP-OVA; 2,4-Dinitrophenol-conjugated ovalbum
A genetic library screen for signaling proteins that interact with phosphorylated T cell costimulatory receptors
Keywords: کوتیزولاتور قابل انعطاف; Functional genomics; Genetic screening; T lymphocytes; Costimulation; Phosphorylation; Inducible costimulator; Phosphatidylinositol 3-kinase;
Role of inducible costimulator in the development of lupus in MRL/lpr mice
Keywords: کوتیزولاتور قابل انعطاف; Lupus; MRL/lpr mice; Inducible costimulator; Glomerulonephritis
The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis
Keywords: کوتیزولاتور قابل انعطاف; Allergic conjunctivitis; B7 related protein-1; Eosinophil; Experimental immune-mediated blepharoconjunctivitis; Immunoglobulin; Inducible costimulator; Mouse; T cell; T helper 1; T helper 2;
Common Variable Immunodeficiency: Test Indications and Interpretations
Keywords: کوتیزولاتور قابل انعطاف; BAFF-R; B-cell activation factor of the tumor necrosis factor family receptor; CVID; common variable immunodeficiency; ICOS; inducible costimulator; MHC; major histocompatibility complex; TACI; trans-membrane activator, calcium modulator, and cyclophilin
Molecular regulation of Th2 immunity by dendritic cells
Keywords: کوتیزولاتور قابل انعطاف; Dendritic cells; Asthma; Allergies; Th2 immunity; CCL; CC chemokine receptor ligand; CCR; chemokine receptor that binds CC chemokines; CpG; specific unmethylated, immunostimulatory oligonucleotides; CTLA4; cytotoxic T lymphocyte antigen 4; CXCL; CXC chemo