دانلود مقالات ISI درباره Irs + ترجمه فارسی

لپتین در بیماری کبدی چربی غیرالکلی: یک بررسی روایت

Leptin in nonalcoholic fatty liver disease: A narrative review

Keywords: AMPK; 5′-adenosine monophosphate-activated protein kinase; BMI; body mass index; CHB; chronic hepatitis B; CHC; chronic hepatitis C; ChREBP; carbohydrate response element binding protein; Fox; forkhead box protein; HCC; hepatocellular carcinoma; HSCs;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

دی هیدروتستوسترون باعث انتقال سیگنالینگ و انتقال گلوکز قلب در مدل موش سندرم تخمدان پلی کیستیک می شود

Dihydrotestosterone deteriorates cardiac insulin signaling and glucose transport in the rat model of polycystic ovary syndrome

Keywords: PCOS; polycystic ovary syndrome; DHT; dihydrotestosterone; GLUT; glucose transporter; IR; insulin receptor; IRS; insulin receptor substrate; MAPK; mitogen-activated protein kinase; Akt; protein kinase B; ERK1/2; extracellular signal regulated kinases 1/2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

کمبود اندام جنسی در شروع حساسیت حساس به بافت چربی سفید با سن همراه است

Sex dimorphism in the onset of the white adipose tissue insulin sensitivity impairment associated with age

Keywords: Age; White adipose tissue; Insulin sensitivity; Adiponectin; Sex dimorphism; AdipoR1; adiponectin receptor 1; Akt and p Akt; total and phosphorylated Ser/Thr kinase A; AMPK and pAMPK; total and phosphorylated adenosine monophosphate-activated protein kina

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

ریفلاکس عروق کرونر بعد از یکبار پس از یکبار پیوند مجدد: عوامل پیش بینی کننده و نتایج بالینی

New Contralateral Vesicoureteral Reflux after Unilateral Ureteral Reimplantation: Predictive Factors and Clinical Outcomes

Keywords: vesico-ureteral reflux; surgical procedures; operative; follow-up studies; BC; bladder capacity; C-VUR; contralateral vesicoureteral reflux; IRS; International Reflux Study; RNC; radionuclide cystogram; UTI; urinary tract infection; VCUG; voiding cystoure

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

کبد تابع میتوکندری را به حالت های مقاوم به انسولین و دیابتی در موش بستگی دارد

Liver adapts mitochondrial function to insulin resistant and diabetic states in mice

Keywords: HFD; high fat diet; STZ; streptozocin; IR; insulin receptor; IRS; insulin receptor substrate; RC; respiratory chain; TCC; tricarboxylic acid cycle; Type 2 diabetes mellitus; Mitochondrial biogenesis; Mitochondrial gene expression; Insulin receptor; Liver

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

خطرات سرطان از درمان های دیابت: ارزیابی شواهد

Cancer risks from diabetes therapies: Evaluating the evidence

Keywords: Diabetes; Cancer; Insulin; Anti-diabetics; Cannabinoid; Obesity; 2-AG; 2-arachidonoyl glycerol; ACC; acetyl-CoA carboxylase; AMPK; adenosine monophosphate-activated protein kinase; CB1R; cannabinoid 1 receptor; CB2R; cannabinoid 2 receptor; CPT-1; carniti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

تنظیم چاقی و مقاومت به انسولین توسط اکسید نیتریک

Regulation of obesity and insulin resistance by nitric oxide

Keywords: 3-NT; 3-nitrotyrosine; ADMA; asymmetric dimethyl arginine; Akt; protein kinase B; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; BH2; dihydrobiopterin; BH4; tetrahydrobiopterin; BMR; basal metabolic rate; Cav-1; caveolin-1; CCK; cholecysto

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

سلول و مولکولی در التهاب بافت چربی در ایجاد مقاومت به انسولین ناشی از چاقی

Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance

Keywords: ABCA; ATP-binding cassette transporter; AIM; Apoptosis inhibitor of macrophage; APC; antigen-presenting cell; ASC; apoptotic speck protein containing a caspase recruitment domain; AT; adipose tissue; ATM; AT macrophage; BLT; leukotriene B4 receptor; BM; b

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

بینش اخیر در پاتوفیزیولوژی مولکولی تشکیل قطرات چربی در سلولهای کبدی

Recent insights into the molecular pathophysiology of lipid droplet formation in hepatocytes

Keywords: ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2014 سفارش ترجمه

نقش استرس اکسیداتیو در نارسایی سیگنالینگ انسولین با آسیب عضلانی ناشی از ورزش

Role of oxidative stress in impaired insulin signaling associated with exercise-induced muscle damage

Keywords: 4-HNE; 4-hydroxy-2-nonenal; AMPK; AMP-activated kinase; CaMK; Ca2+/calmodulin-dependent protein kinase; CK; creatine kinase; GLUT4; glucose transporter 4; IKK; IκB kinase; IL; interleukin; IRS; insulin receptor substrate; MAPK; mitogen-activated protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

رنگ بنفش سیب زمینی شیرین باعث کاهش مقاومت به انسولین کبدی از طریق مسدود شدن استرس اکسیداتیو و استرس رتیکولوم اندوپلاسمی در موش های درمان شده با رژیم غذایی با چربی بالا

Purple sweet potato color attenuates hepatic insulin resistance via blocking oxidative stress and endoplasmic reticulum stress in high-fat-diet-treated mice

Keywords: PSPC; purple sweet potato color; HFD; high-fat diet; NAFLD; nonalcoholic fatty liver disease; T2D; type 2 diabetes; ER stress; endoplasmic reticulum stress; TG; triglyceride; TC; total cholesterol; ALT; alanine aminotransferase; AST; aspartate aminotransf

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

عضلانی که سرطان دارد

Muscle wasting in cancer

Keywords: ACTRIIB; activin receptor type-2B; APC; adenomatosis polyposis coli; APPR; acute phase protein response; ARC; arcuate nucleus; ATP; adenosine-5′-triphosphate; C-26; colon-26 adenocarcinoma mouse model; CHO; Chinese hamster ovary; COPD; chronic obstructi

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

نقش بالقوه و منافع درمانی مایوآنزیتول در بیماریهای متابولیکی

Potential role and therapeutic interests of myo-inositol in metabolic diseases

Keywords: Inositol; Insulin resistance; Diabetes; Polycystic ovary syndrome; Metabolic syndrome; Diabetic neuropathy; AC; adenylyl cyclase; ACC; acetyl-coenzyme A carboxylase; AGEs; advanced glycation end products; AMP; adenosine monophosphate; cAMP; cyclic AMP; AM

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

زیست شناسی رادیکال آزاد برای پزشکی: یادگیری از بیماری کبدی چربی غیرالکلی

Free radical biology for medicine: learning from nonalcoholic fatty liver disease

Keywords: ROS; reactive oxygen species; NR; nuclear receptor; FA; fatty acid; TAG; triacylglycerol; MCD; malonyl-CoA decarboxylase; ACC; acetyl-CoA carboxylase; FAS; fatty acid synthase; SCD1; stearoyl-CoA desaturase-1; G-3-P; glycerol 3-phosphate; CPT-1; carnitine

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Transurethral resection for botryoid bladder rhabdomyosarcoma

Keywords: Rhabdomyosarcoma; Transurethral resection; Conservative surgery; TUR-BT; Transurethral resection of a bladder tumor; CT; Computed tomography; IRS; Intergroup Rhabdomyosarcoma Study; SIOP; International Society of Pediatric Oncology; MMT; Malignant Mesench

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanism of insulin-like effect of chromium(III) ions on glucose uptake in C2C12 mouse myotubes involves ROS formation

Keywords: DCFH DA; dichorodihydrofluorescein diacetate; DCFH 2′,7′; dichorodihydrofluorescein; DCF 2′,7′; dichorofluorescein; DMEM; dulbecco modified eagle's medium; DOG; deoxyglucose; DPI; diphenyleneiodonium; GTF; glucose tolerance factor; GLUT4; glucos

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Exposure to DDT and hypertensive disorders of pregnancy among South African women from an indoor residual spraying region: The VHEMBE study

Keywords: BP; blood pressure; CI; confidence interval; GM; geometric mean; GSD; geometric standard deviation; HDP; hypertensive disorders of pregnancy; DDT; Dichlorodiphenyl trichloroethane; DDE; Dichlorodiphenyl dichloroethylene; DDT/E; DDT and DDE; IRS; Indoor Re

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Rho kinase, a potential target in the treatment of metabolic syndrome

Keywords: WHO; World Health Organization; NCEP-ATP III; the National Cholesterol Education Program Adult Treatment Panel III; IDF; the International Diabetes Federation; JIS; the Joint Interim Societies; NCEP; National Cholesterol Education Program; MetS; metabolic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Smad4/Fascin index is highly prognostic in patients with diffuse type EBV-associated gastric cancer

Keywords: EBV; Epstein-Barr virus; EBVaGC; EBV-associated gastric adenocarcinoma; AGC; advanced gastric cancer; IRS; immunoreactive score; ISH; In situ hybridization; DFS; Disease-free survival; OS; Overall survival; EGFR; epidermal growth factor receptor; Smad4 pr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Impairment of bisphenol F on the glucose metabolism of zebrafish larvae

Keywords: BPF; bisphenol F; BPA; bisphenol A; BPS; bisphenol S; IR; insulin receptor; IRS; insulin receptor substrate; PEPCK; phosphoenolpyruvate carboxykinase; DMSO; dimethyl sulfoxide; hpf; hour past fertilization; PCR; polymerase chain reaction; PEPCK-M; mitocho

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Alterations in male reproductive hormones in relation to environmental DDT exposure

Keywords: AR; Androgen receptor; BDL; Below detection limit; BFRs; Brominated flame retardants; BMI; Body mass index; b-T; Bioavailable testosterone; CYP19; Aromatase; DDE; 1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene; DDT; 1, 1, 1-trichloro-2,2-bis (p-chloropheny

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Bisphenol S exposure impairs glucose homeostasis in male zebrafish (Danio rerio)

Keywords: BPS; bisphenol S; BPA; bisphenol A; FBG; fasting blood glucose; IRs; insulin receptors; IRS/PI3K/Akt; insulin receptor substrates/phosphotidylinositol 3-kinase/Akt; GP; glycogen phosphorylase; PEPCK; phosphoenolpyruvate carboxykinase; G6Pase; glucose-6-ph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance

Keywords: Adipose tissue; Antipsychotics; Fatty acid; Fatty liver; Insulin resistance; Sulpiride; ACC; acetyl-CoA carboxylase; Adipo-IR; adipose tissue insulin resistance; AUC; area under the curve; ChREBP; carbohydrate-response element-binding protein; D2R; dopami

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Occurrence of sulfonated steroids and ovarian expression of steroid sulfatase and SULT1E1 in cyclic cows

Keywords: A4; androstenedione; AnDiolS; 5-androstene-3β,17β-diol sulfate; An; androsterone; AnS; androsterone sulfate; APCI; atmospheric pressure chemical ionization; CholS; cholesterol sulfate; CL; corpus luteum; COCs; cumulus-oocyte-complexes; DHEA; dehydroepia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Therapeutic effects of the allosteric protein tyrosine phosphatase 1B inhibitor KY-226 on experimental diabetes and obesity via enhancements in insulin and leptin signaling in mice

Keywords: PTP1B inhibitor; Diabetes; Obesity; Allosteric inhibitor; db/db mouse; EDTA; ethylenediaminetetraacetic acid; FBS; fetal bovine serum; GLUT4; glucose transporter type 4; GPDH; glycerol-3-phosphate dehydrogenase; HbA1c; hemoglobin A1c; HFD; high-fat diet;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effects of (-)-epicatechin and the colonic metabolite 3,4-dihydroxyphenylacetic acid against glucotoxicity-induced insulin signalling blockade and altered glucose uptake and production in renal tubular NRK-52E cells

Keywords: Colonic-derived flavonoid metabolites; Epicatechin; Glucose homeostasis; Glucotoxicity; Insulin signalling pathway; NRK-52E cells; AKT/PKB; protein kinase B; AMPK; 5′-AMP-activated protein kinase; DHBA; 2,3-dihydroxybenzoic acid; DHPAA; 3,4-dihydroxyphe

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway

Keywords: Ganoderic Acid A; SREBPs; Obesity; Insulin resistance; Lipid accumulation; ABCA1; ATP-binding cassette transporter 1; ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; BAT; brown adipose tissue; CPT1; carntine palmitoyltransferase 1; CYP7A1; cholesterol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Re-evaluating the role of FOXOs in cancer

Keywords: RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Association between Type I interferon and depletion and dysfunction of endothelial progenitor cells in C57BL/6 mice deficient in both apolipoprotein E and Fas ligand

Keywords: SLE; systemic lupus erythematosus; EPCs; endothelial progenitor cells; IFN-I; type I interferon; FACS; fluorescence-activated cell sorting; FITC-UEA-1; fluorescein isothiocyanate labeled Ulex europaeus agglutinin 1; DII-ac-LDL; 3′-tetramethylindocarbocy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Adiponectin AS lncRNA inhibits adipogenesis by transferring from nucleus to cytoplasm and attenuating Adiponectin mRNA translation

Keywords: AdipoQ; Adiponectin; AS lncRNA; antisense long noncoding RNA; FISH; fluorescence in situ hybridization; RPA; ribonuclease protection assay; iWAT; inguinal white adipose tissue; eWAT; epididymal white adipose tissue; BAT; brown adipose tissue; TG; triglyce

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNAs link chronic inflammation in childhood to growth impairment and insulin-resistance

Keywords: ALS; acid-labile subunit; APC; antigen-presenting cell; CXCL2; chemokine (C-X-C motif) ligand 2; ESR; erythrocyte sedimentation rate; FGFR1; fibroblast growth factor receptor 1; FOXO1; Forkhed box O1; FOXP3; forkhead box P3; GH; growth hormone; GHR; growt

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Helicobacter pylori induces direct activation of the lymphotoxin beta receptor and non-canonical nuclear factor-kappa B signaling

Keywords: CagA; cytotoxin-associated gene A; cagPAI; cytotoxin-associated gene pathogenicity island; cIAP; cellular inhibitor of apoptosis protein; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HBV; hepatitis B virus; HCV; hepatitis C virus; IκBα; NF-kappa-B i

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Folate receptor α is associated with poor clinicopathological perspectives in breast carcinoma

Keywords: FRα; folate receptor alpha; IDC; invasive duct carcinoma; NOS; not otherwise specified; AJCC; American Joint Committee of Cancer; ER; estrogen receptor; PR; progesterone receptor; Her-2 neu; human epidermal growth factor receptor- 2; EGFRs; epidermal gro

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

The molecular aspects of oxidative & nitrosative stress and the tryptophan catabolites pathway (TRYCATs) as potential causes of depression

Keywords: BDNF; brain-derived neurotrophic factor; CAT; catalase; CIRS; compensatory (anti)inflammatory reflex system; CoQ10; coenzyme Q10; DD; depressive disorders; GPx; glutathione peroxidise; GR; glutathione reductase; GSH; glutathione; HDL-c; high-density lipop

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study

Keywords: Diabetes mellitus; PTP1B inhibition; Flavonoids; Enzymatic inhibition type; DM; Diabetes mellitus; GLUT4; glucose transporter 4; IR; insulin receptor; IRS; insulin receptor substrates; Km; Michaelis constant; PKB; protein kinase B; pNPP; p-nitrophenyl pho

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

CAR-T cells and combination therapies: What's next in the immunotherapy revolution?

Keywords: CAR; chimeric antigen receptor; iRs; inhibitory receptors; mAbs; monoclonal antibodies; SMIs; Small molecule inhibitors; KIs; kinase inhibitors; CAR-T cells; Solid tumors; Targeted-therapies; Combination therapies; Synthetic biology; Systems biology;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Stimulation of liver IGF-1 expression promotes peak bone mass achievement in growing rats: a study with pomegranate seed oil

Keywords: PSO; pomegranate seed oil; PBM; peak bone mass; BMD; bone mineral density; HDAC; histones deacetylases; IGF-1; insulin growth factor-1; IRS; insulin receptor substrate; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; CH

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

The Crambe abyssinica plastome: Brassicaceae phylogenomic analysis, evolution of RNA editing sites, hotspot and microsatellite characterization of the tribe Brassiceae

Keywords: NCBI; National Center for Biotechnology Information; tRNA; transfer RNA; rRNA; ribosomal RNA; LSC; large single-copy; SSC; small single-copy; IRs; inverted repeats; bp; base pairs; RAPD; Random Amplified Polymorphism DNA; RFLP; Restriction Fragment Length

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

FGF2 and FAM201A affect the development of osteonecrosis of the femoral head after femoral neck fracture

Keywords: ONFH; osteonecrosis of the femoral head; FNF; femoral neck fracture; DEGs; differentially expressed genes; PPI; protein-protein interaction; VEGF; vascular endothelial growth factor; HIF-1α; hypoxia-inducible factor-1 alpha; OPG; osteoprotegerin; RANK; r

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes

Keywords: ACE; angiotensin-converting enzyme; AD; Alzheimer's disease; Aß; amyloid ß-protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECE; endothelin-converting enzyme; EDTA; ethylenediaminetetraacetic acid; EGCG; epigallocatechi

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1

Keywords: GSK3β; glycogen synthase kinase 3β; HFD; high-fat diet; HMGA1; high mobility group AT-hook 1; IR; insulin receptor; IRS; insulin receptor substrate; NAFLD; nonalcoholic fatty liver disease; G9a/EHMT2; Hepatic insulin signaling; Insulin receptor; HMGA1;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Astaxanthin: A mechanistic review on its biological activities and health benefits

Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3: The art of multi-tasking of metabolic and immune functions in obesity

Keywords: Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

Keywords: Nrf2; type 2 diabetes; natural products; hyperglycemia; cellular stress; insulin sensitivity; β-cell function; vascular complications; AGE; advanced glycation end products; AhR; arylhydrocarbon receptor; AMPK; AMP-activated kinase; ARE; antioxidant respo

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination

Keywords: Insulin-like growth factor (IGF); Insulin receptor substrate (IRS)-2; Ubiquitin-specific protease 15 (USP15); Nedd4; Ubiquitination; IGF; insulin-like growth factor; IRS; insulin receptor substrate; PI3K; phosphatidylinositol 3-kinase; USP; ubiquitin-spec

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Gln223Arg polymorphism in the Caucasian population and Pro1019Pro polymorphism in the Chinese population are risk factors for OSAS: An updated meta-analysis of 1159 subjects

Keywords: ACC; acetyl-CoA carboxylase; AMPK; 5′ adenosine monophosphate-activated protein kinase; CI; confidence intervals; CNKI; Chinese National Knowledge Infrastructure; Grb2; growth factor receptor-bound protein 2; HWE; Hardy-Weinberg equilibrium; IRS; insu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system

Keywords: AAF; L-alanyl-N-[(1S)−3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide, mono trifluoro-acetate; ALLN; N-acetyl-L-leucyl-N-[(1S)−1-formylpentyl]-L-leucinamide; Cal III; N-[(1S)−1-[[(1-formyl-2-phenylethyl)amino]carbonyl]−2-methylpropyl]-carbami

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleLFG-500, a novel synthetic flavonoid, suppresses epithelial-mesenchymal transition in human lung adenocarcinoma cells by inhibiting NLRP3 in inflammatory microenvironment

Keywords: Inflammatory microenvironment; Epithelial-mesenchymal transition; NLRP3; Human lung adenocarcinoma; LFG-500; CM; conditioned medium; H&E; hematoxylin and eosin; IRS; immunoreactivity score; IL-1β; interleukin-1β; IL-6; interleukin-6; MAPK; mitogen-act

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

The methanolic fraction of Centratherum anthelminticum seed downregulates pro-inflammatory cytokines, oxidative stress, and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats

Keywords: γ-GT; γ-glutamyl transpeptidase; ALP; alkaline phosphatase; ALT; alanine transaminase; ANOVA; analysis of variance; AST; aspartate transaminase; ATCC; American Type Culture Collection; bw; body weight; CA; Centratherum anthelminticum; CAMFs; crude metha

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1

Keywords: Insulin-like growth factor; Nitric oxide; S-Nitrosylation; Signal transduction; ERK; extracellular signal-regulated protein kinase; IGF-1; insulin-like growth factor-1; IGF-1R; insulin-like growth factor-1 receptor; IRS; insulin receptor substrate; MAPK;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه